Santa Clara Holidays from £835
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Your Santa Clara Holiday
Enjoy amazing adventures when you lock in a holiday package to Santa Clara. Whether you're a history buff, art enthusiast or just a traveller who loves discovering new places, there's something for everyone in this lively city. Every trip to Santa Clara needs a well-planned itinerary. Fill yours with big-name attractions like Farallon Island, La Casa de Lourdes Outdoor Spa and Parroquia Santiago Apóstol de Río Hato. Stop dreaming and start travelling. Explore the many options on Expedia today and put your Santa Clara holiday plans in motion!
Top Santa Clara Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
American Trade Hotel
Casco Viejo
£835
per person
2 Oct - 8 Oct
found 17 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
9.4/10 Exceptional! (796 reviews)
room was clean & comfortable. was facing herrara sq so a bit noisy at nite cos of all action incase that may may appeal to everyone. enjoyed my staty, food was delish
Reviewed on 25 Aug 2026
Central Hotel Panama Casco Viejo
Casco Viejo
£917
per person
6 Nov - 10 Nov
found 1 day ago
Return direct flight included
London (LON) to Panama City (PTY)
9.2/10 Wonderful! (1,005 reviews)
This was the most unpleasant check-in experience I’ve ever had. I arrived at 8:30 a.m. and understood that rooms might not be ready, but I was told I’d have to pay over $200 for early check-in. I decided to wait instead. When I finally checked in, I mentioned a message I had received from the hotel, and the front desk agent mocked me for it — incredibly rude. The room has no view and not clean. I don’t understand how come many visitors left decent reviews. I would never recommend or return to this hotel.
Reviewed on 29 Aug 2026
Santa Clara Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Population | 600 |
Max Temp Winter | 29ºC |
Max Temp Summer | 29ºC |
Top Sights | Parroquia Santiago Apóstol de Río Hato, Farallon Island and La Casa de Lourdes Outdoor Spa |
Top hotels in Santa Clara
Villa Botero By Casa Mojito B&B
Calle Central, 5 Rio Hato Cocle
£81
31 Aug - 1 Sept
includes taxes & fees
9.8/10 Exceptional! (69 reviews)
"Christophe and his family were amazing hosts. The breakfast was incredible and fit for a king. The grounds, room and pool were decorated beautifully and very well maintained. We would stay here again in a heartbeat. We highly recommend this place."
Reviewed on 17 Jun 2026
Chic 1-bedroom with WiFi and AC in enchanting Río Hato
Río Hato Provincia de Coclé
Gran Evenia Bijao - All Inclusive
Carretera Interamericana km 108, guias de Anton Rio Hato Coclé
Fully refundableReserve now, pay when you stay
£156
1 Sept - 2 Sept
includes taxes & fees
8.2/10 Very good! (1,001 reviews)
"Great place for families, close proximity to the beach, vast variety of food, helpful and polite staff."
Reviewed on 29 Aug 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in Santa Clara
Valle De Anton Rainfall Hot Springs and Nature Private Tour
£70
per adult
Frequently asked questions
How much does a Santa Clara travel package cost?
Customize your Santa Clara travel package from a low £835. Choose from any combination of rental cars, flights and hotels to put together the getaway you've been dreaming about. Don't forget to add on some tours and experiences!
If I'm not able to travel, can I cancel my Santa Clara travel package?
If your travel plans in Santa Clara have been upended, it's comforting to know that you can cancel your booking. If you made your booking less than 24 hours ago, you may be eligible to receive a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may charge a cancellation fee. To learn more, check our Customer Service Portal.
How do I get a cheap travel package to Santa Clara?
Bundle your bookings with Expedia to save big bucks on your next getaway. With more than 550 partner airlines and 1,000,000 hotel options across the globe, your Santa Clara travel package can be customized exactly to suit your travel style. With all that extra money, why not add one or two interesting tours and experiences? It's an easy way to unlock even more discounts. Your dream holiday in Santa Clara is much closer than you thought!
Does Expedia offer Book Now, Pay Later Santa Clara holidays?
Your bank balance shouldn't stop you from going on holiday, so Expedia has devised a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book a fabulous getaway without exhausting your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your trip. Consider one of these flexible payment options:
- Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's convenient monthly instalment plans. If paying a little each month works for you, choose this option at checkout.
- Pay in instalments holidays: If you'd prefer to pay off your getaway in multiple transactions, holidays paid in instalments might be right for your Book Now, Pay Later holiday through Klarna.
- Low deposit holidays: When you want to grab an awesome deal but your budget doesn't quite go that far, Klarna's low deposit holiday plan will help you lock in your escape.
Where should I stay in Santa Clara?
If you plan to check out Farallon Island, give commuting a miss and find a place to stay close by. It's one of the most popular attractions in the area.
What are the top hotels in Santa Clara?
Get your escape off to a fantastic start by booking a stay at Playa Blanca Beach Resort. It's one of most popular hotels in Santa Clara. Another comfortable option is Royal Decameron Panama.
How far in advance should I book my Santa Clara holiday?
Savvy travellers always book early. Air carriers typically release flights up to 12 months ahead of departure, and this is a fantastic opportunity to land some rock-bottom prices. Boss just told you to use up your holiday time next week? Don't fret. Expedia are never short of fantastic bargains to whisk you away on the getaway of your dreams, at a price you can afford.
What does an Expedia Santa Clara travel package include?
It depends on what type of trip you have in the works. Santa Clara holiday deals can include hotels, flights and car rentals. You can mix and match to find the package that fits your needs. You can also add on activities and experiences after you've booked to get even bigger discounts.
What should I know before booking a Santa Clara travel package?
Tailor deals that suit your budget with an Expedia package. Flights, hotels, rental cars — we've got everything you need to plan your getaway. You'll save loads just for combining your bookings. Whether you're embarking on a winter adventure or sipping cocktails on a beach, your ideal holiday is just a few clicks away.
Can I choose my airline with a Santa Clara Expedia travel package?
Yes — that's the beauty of an Expedia package. You're the boss! We have more than 550 airline partners all over the world, so you have lots of choice when creating your Santa Clara adventure.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
