Santa Clara Holidays from £838

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Your Santa Clara Holiday

Enjoy amazing adventures when you lock in a holiday package to Santa Clara. Whether you're a history buff, art enthusiast or just a traveller who loves discovering new places, there's something for everyone in this lively city. Every trip to Santa Clara needs a well-planned itinerary. Fill yours with big-name attractions like Farallon Island, La Casa de Lourdes Outdoor Spa and Parroquia Santiago Apóstol de Río Hato. Stop dreaming and start travelling. Explore the many options on Expedia today and put your Santa Clara holiday plans in motion!

Top Santa Clara Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Punta Paitilla
Price was £1,099, price is now £838 per person
£838
per person
11 Oct - 17 Oct
found 2 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
8.4/10 Very Good! (1,033 reviews)
Everything was good and convenient

Reviewed on 20 Aug 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was £1,587, price is now £1,054 per person
£1,054
per person
11 Oct - 17 Oct
found 2 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
9/10 Wonderful! (974 reviews)
Everyone was very friendly and super helpful. Location was super convenient. Will definitely stay again.

Reviewed on 20 Aug 2025

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5 out of 5
Bella Vista
Price was £1,272, price is now £957 per person
£957
per person
11 Oct - 17 Oct
found 2 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
9.2/10 Wonderful! (1,003 reviews)
A lovely hotel and excellent food and rooms and service.

Reviewed on 17 Aug 2025

Hotel La Compania, in the Unbound Collection by Hyatt

Hotel La Compania, in the Unbound Collection by Hyatt

4.5 out of 5
Casco Viejo
Price was £1,504, price is now £1,143 per person
£1,143
per person
11 Oct - 17 Oct
found 2 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
9.8/10 Exceptional! (227 reviews)
This place is perfect. Great rooftop bar.

Reviewed on 22 Aug 2025

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Punta Paitilla
Price was £1,096, price is now £855 per person
£855
per person
11 Oct - 17 Oct
found 2 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
8.8/10 Excellent! (1,003 reviews)
Great staff and accommodations

Reviewed on 21 Aug 2025

Santa Clara Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
600
Max Temp Winter
29ºC
Max Temp Summer
29ºC
Top Sights
Parroquia Santiago Apóstol de Río Hato, Farallon Island and La Casa de Lourdes Outdoor Spa

Top hotels in Santa Clara

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Calle Central, 5, Rio Hato, Cocle
9.6/10 Exceptional! (60 reviews)
"Wonderful little hotel. With only three"

Reviewed on 21 Apr 2025

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Villa Botero By Casa Mojito B&B
Loft Pres de la mer a 1 km de la mer Tres Calme Avec Beaucoup de Securite bbq ac

Loft Pres de la mer a 1 km de la mer Tres Calme Avec Beaucoup de Securite bbq ac

Río Hato
The price is £73 per night from 23 Aug to 24 Aug
£73
23 Aug - 24 Aug
includes taxes & fees
Loft Pres de la mer a 1 km de la mer Tres Calme Avec Beaucoup de Securite bbq ac
Las Sirenas de Santa Clara

Las Sirenas de Santa Clara

3 out of 5
Carretera Interamericana Km.113, Rio Hato, Cocle
Excelente lugar para Familia - Enfocarse en eso!!
"Todo estuvo perfecto, solo pienso que si deben controlar un poco las personas que se hospedan en las cabañas, ejemplo: todas las cabañas que estábamos eramos familias con niños solo una donde todos eran jóvenes, esa cabaña tenia música y bulla hasta altas horas de la noche y aunque varios de las ..."

Reviewed on 2 May 2017

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Las Sirenas de Santa Clara
See all 603 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Popular places to visit

Playa Blanca

Playa Blanca

Nothing says holiday like spending a lazy day at Playa Blanca, a popular beach in Rio Hato. Amble around this family-friendly area's seaside or experience its entertainment venues.

Playa Blanca
Farallón Beach

Farallón Beach

If a restful holiday is part of your travel plans, Farallón Beach might be the perfect place to visit during your trip to El Farallón del Chirú. While you're here, you can savour the top-notch restaurants.

Farallón Beach

Farallon Island

Commune with nature and explore the great outdoors at Farallon Island during your travels in Rio Hato. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants.

Farallon Island

What to do in Santa Clara

Jungle ATV Waterfall and Zipline Adventure from Panama City

Jungle ATV Waterfall and Zipline Adventure from Panama City

£140
per adult
Jungle ATV Waterfall and Zipline Adventure from Panama City
Picture 4 for Activity Panama City: Ultimate ATV Jungle & Volcano Adventure

Panama City: Ultimate ATV Jungle & Volcano Adventure

£121
per adult
Panama City: Ultimate ATV Jungle & Volcano Adventure
Experience the thrill of off-road adventure with our ATV Jungle Tour in Panama City. Navigate through lush forests and rugged terrain for an unforgettable ride.

Panama City: ATV Jungle Adventure Discover Volcano & Waterfall

£129
per adult
100% of travellers recommend
Panama City: ATV Jungle Adventure Discover Volcano & Waterfall
See all activities in Santa Clara

Frequently asked questions

How much does a Santa Clara travel package cost?
Customize your Santa Clara travel package from a low £838. Choose from any combination of rental cars, flights and hotels to put together the getaway you've been dreaming about. Don't forget to add on some tours and experiences!
If I'm not able to travel, can I cancel my Santa Clara travel package?
If your travel plans in Santa Clara have been upended, it's comforting to know that you can cancel your booking. If you made your booking less than 24 hours ago, you may be eligible to receive a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may charge a cancellation fee. To learn more, check our Customer Service Portal.
How do I get a cheap travel package to Santa Clara?
Bundle your bookings with Expedia to save big bucks on your next getaway. With more than 550 partner airlines and 1,000,000 hotel options across the globe, your Santa Clara travel package can be customized exactly to suit your travel style. With all that extra money, why not add one or two interesting tours and experiences? It's an easy way to unlock even more discounts. Your dream holiday in Santa Clara is much closer than you thought!
Does Expedia offer Book Now, Pay Later Santa Clara holidays?
Your bank balance shouldn't stop you from going on holiday, so Expedia has devised a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book a fabulous getaway without exhausting your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your trip. Consider one of these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's convenient monthly instalment plans. If paying a little each month works for you, choose this option at checkout.
  • Pay in instalments holidays: If you'd prefer to pay off your getaway in multiple transactions, holidays paid in instalments might be right for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: When you want to grab an awesome deal but your budget doesn't quite go that far, Klarna's low deposit holiday plan will help you lock in your escape.

Where should I stay in Santa Clara?
If you plan to check out Farallon Island, give commuting a miss and find a place to stay close by. It's one of the most popular attractions in the area.
What are the top hotels in Santa Clara?
Get your escape off to a fantastic start by booking a stay at Playa Blanca Beach Resort. It's one of most popular hotels in Santa Clara. Another comfortable option is Royal Decameron Panama.
How far in advance should I book my Santa Clara holiday?
Savvy travellers always book early. Air carriers typically release flights up to 12 months ahead of departure, and this is a fantastic opportunity to land some rock-bottom prices. Boss just told you to use up your holiday time next week? Don't fret. Expedia are never short of fantastic bargains to whisk you away on the getaway of your dreams, at a price you can afford.
What does an Expedia Santa Clara travel package include?
It depends on what type of trip you have in the works. Santa Clara holiday deals can include hotels, flights and car rentals. You can mix and match to find the package that fits your needs. You can also add on activities and experiences after you've booked to get even bigger discounts.
What should I know before booking a Santa Clara travel package?
Tailor deals that suit your budget with an Expedia package. Flights, hotels, rental cars — we've got everything you need to plan your getaway. You'll save loads just for combining your bookings. Whether you're embarking on a winter adventure or sipping cocktails on a beach, your ideal holiday is just a few clicks away.
Can I choose my airline with a Santa Clara Expedia travel package?
Yes — that's the beauty of an Expedia package. You're the boss! We have more than 550 airline partners all over the world, so you have lots of choice when creating your Santa Clara adventure.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.