Santa Clara Holidays from £816

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Your Santa Clara Holiday

Enjoy amazing adventures when you lock in a holiday package to Santa Clara. Whether you're a history buff, art enthusiast or just a traveller who loves discovering new places, there's something for everyone in this lively city. Every trip to Santa Clara needs a well-planned itinerary. Fill yours with big-name attractions like Farallon Island, La Casa de Lourdes Outdoor Spa and Parroquia Santiago Apóstol de Río Hato. Stop dreaming and start travelling. Explore the many options on Expedia today and put your Santa Clara holiday plans in motion!

Top Santa Clara Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Faranda Guayacanes, a member of Radisson Individuals

Hotel Faranda Guayacanes, a member of Radisson Individuals

3 out of 5
Price was £853, price is now £816 per person
£816
per person
26 Aug - 30 Aug
just found
Return direct flight included
London (LON) to Panama City (PTY)
8/10 Very good! (336 reviews)
El personal fue muy amable desde la recepcionista hasta los meseros en los restaurante

Reviewed on 14 Jul 2026

Villa Marina Hotel

Villa Marina Hotel

3.5 out of 5
Price was £1,298, price is now £1,131 per person
£1,131
per person
26 Aug - 30 Aug
just found
Return direct flight included
London (LON) to Panama City (PTY)
9/10 Wonderful! (163 reviews)
staff helpful and very friendly, rooms super clean.

Reviewed on 27 Jun 2026

Chitre Villa by Otium

Chitre Villa by Otium

2 out of 5
Price was £996, price is now £885 per person
£885
per person
26 Aug - 30 Aug
just found
Return direct flight included
London (LON) to Panama City (PTY)
No reviews

Alaya Yoga & Surf & Retreat

Alaya Yoga & Surf & Retreat

4 out of 5
Price was £1,928, price is now £1,761 per person
£1,761
per person
26 Aug - 30 Aug
just found
Return direct flight included
London (LON) to Panama City (PTY)
9.4/10 Exceptional! (18 reviews)
Fantastic place to stay. Everything was premium. Bed was spectacular left after two years feeling super replaced. Would recommend highly.

Reviewed on 10 Feb 2026

Sansara Surf and Yoga Resort - Retreat

Sansara Surf and Yoga Resort - Retreat

4.5 out of 5
Price was £1,214, price is now £1,143 per person
£1,143
per person
26 Aug - 30 Aug
just found
Return direct flight included
London (LON) to Panama City (PTY)
9.2/10 Wonderful! (10 reviews)

Santa Clara Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
600
Max Temp Winter
29ºC
Max Temp Summer
29ºC
Top Sights
Parroquia Santiago Apóstol de Río Hato, Farallon Island and La Casa de Lourdes Outdoor Spa

Top hotels in Santa Clara

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Calle Central, 5 Rio Hato Cocle
The price is £80 per night from 21 Jul to 22 Jul
£80
21 Jul - 22 Jul
includes taxes & fees
9.8/10 Exceptional! (69 reviews)
"Christophe and his family were amazing hosts. The breakfast was incredible and fit for a king. The grounds, room and pool were decorated beautifully and very well maintained. We would stay here again in a heartbeat. We highly recommend this place."

Reviewed on 17 Jun 2026

Villa Botero By Casa Mojito B&B
Chic 1-bedroom with WiFi and AC in enchanting Río Hato

Chic 1-bedroom with WiFi and AC in enchanting Río Hato

Río Hato Provincia de Coclé
Get rates
Chic 1-bedroom with WiFi and AC in enchanting Río Hato
Gran Evenia Bijao - All Inclusive

Gran Evenia Bijao - All Inclusive

3.5 out of 5
Carretera Interamericana km 108, guias de Anton Rio Hato Coclé
The price is £151 per night from 29 Jul to 30 Jul
£151
29 Jul - 30 Jul
includes taxes & fees
8.2/10 Very good! (1,012 reviews)
"We end up checking out early because of issues with the property; still waiting for a refund - the property idea of addressing issue was offering another room, which had the same issues as the others."

Reviewed on 14 Jul 2026

Gran Evenia Bijao - All Inclusive
See all 505 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in Santa Clara

Day Pass Hiking Tour – Antón Valley from Panama City

Anton Hiking Adventure from Panama City

£102
per adult
Anton Hiking Adventure from Panama City
Anton Valley

Valle De Anton Rainfall Hot Springs and Nature Private Tour

£72
per adult
Valle De Anton Rainfall Hot Springs and Nature Private Tour
See all activities in Santa Clara

Frequently asked questions

How much does a Santa Clara travel package cost?
Customize your Santa Clara travel package from a low £816. Choose from any combination of rental cars, flights and hotels to put together the getaway you've been dreaming about. Don't forget to add on some tours and experiences!
If I'm not able to travel, can I cancel my Santa Clara travel package?
If your travel plans in Santa Clara have been upended, it's comforting to know that you can cancel your booking. If you made your booking less than 24 hours ago, you may be eligible to receive a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may charge a cancellation fee. To learn more, check our Customer Service Portal.
How do I get a cheap travel package to Santa Clara?
Bundle your bookings with Expedia to save big bucks on your next getaway. With more than 550 partner airlines and 1,000,000 hotel options across the globe, your Santa Clara travel package can be customized exactly to suit your travel style. With all that extra money, why not add one or two interesting tours and experiences? It's an easy way to unlock even more discounts. Your dream holiday in Santa Clara is much closer than you thought!
Does Expedia offer Book Now, Pay Later Santa Clara holidays?
Your bank balance shouldn't stop you from going on holiday, so Expedia has devised a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book a fabulous getaway without exhausting your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your trip. Consider one of these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's convenient monthly instalment plans. If paying a little each month works for you, choose this option at checkout.
  • Pay in instalments holidays: If you'd prefer to pay off your getaway in multiple transactions, holidays paid in instalments might be right for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: When you want to grab an awesome deal but your budget doesn't quite go that far, Klarna's low deposit holiday plan will help you lock in your escape.

Where should I stay in Santa Clara?
If you plan to check out Farallon Island, give commuting a miss and find a place to stay close by. It's one of the most popular attractions in the area.
What are the top hotels in Santa Clara?
Get your escape off to a fantastic start by booking a stay at Playa Blanca Beach Resort. It's one of most popular hotels in Santa Clara. Another comfortable option is Royal Decameron Panama.
How far in advance should I book my Santa Clara holiday?
Savvy travellers always book early. Air carriers typically release flights up to 12 months ahead of departure, and this is a fantastic opportunity to land some rock-bottom prices. Boss just told you to use up your holiday time next week? Don't fret. Expedia are never short of fantastic bargains to whisk you away on the getaway of your dreams, at a price you can afford.
What does an Expedia Santa Clara travel package include?
It depends on what type of trip you have in the works. Santa Clara holiday deals can include hotels, flights and car rentals. You can mix and match to find the package that fits your needs. You can also add on activities and experiences after you've booked to get even bigger discounts.
What should I know before booking a Santa Clara travel package?
Tailor deals that suit your budget with an Expedia package. Flights, hotels, rental cars — we've got everything you need to plan your getaway. You'll save loads just for combining your bookings. Whether you're embarking on a winter adventure or sipping cocktails on a beach, your ideal holiday is just a few clicks away.
Can I choose my airline with a Santa Clara Expedia travel package?
Yes — that's the beauty of an Expedia package. You're the boss! We have more than 550 airline partners all over the world, so you have lots of choice when creating your Santa Clara adventure.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.