Title: Santa Ana Travel Guide: Best of Santa Ana, Antigua Guatemala Travel 2026 | Expedia.co.uk [Hotels in Santa Ana](https://expedia.co.uk/Santa-Ana-Hotels.d553248635975847775.Travel-Guide-Hotels)[Flights to Antigua Guatemala](https://expedia.co.uk/Cheap-Flights-To-Antigua-Guatemala.d180589.Travel-Guide-Flights)[Things to do in Antigua Guatemala](https://expedia.co.uk/Things-To-Do-In-Antigua-Guatemala.d180589.Travel-Guide-Activities)[Santa Ana Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Ana.d553248635975847775.Car-Hire-Guide)[Santa Ana Holidays](https://expedia.co.uk/Santa-Ana.d553248635975847775.Holidays-City-Breaks) # Santa Ana Travel Guide ## Antigua Guatemala ![Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.](https://images.trvl-media.com/place/553248635975847775/dbfc8e66-dcda-4ff9-9ea4-b39c7cec35ab.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.](https://images.trvl-media.com/place/553248635975847775/dbfc8e66-dcda-4ff9-9ea4-b39c7cec35ab.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santa Ana Things to do Hotels Where to stay [Antigua Guatemala travel guide](https://expedia.co.uk/Antigua-Guatemala.dx180589) --- ### Popular places to visit ![Panoramic inside the ruins of Antigua's Cathedral, one of the many buildings that collapsed after the earthquake that destroyed the city in 1773.](https://images.trvl-media.com/place/180589/1dda07b1-9d1c-4f3b-b652-12e488ea88b5.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Antigua Guatemala Cathedral 5/5(4 reviews) After visiting Antigua Guatemala Cathedral, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's volcano viewpoints or seek out its local tours. [](https://expedia.co.uk/Antigua-Guatemala-Cathedral-Historic-Center.d6266484.Attraction) ![Antigua, Guatemala, volcano](https://images.trvl-media.com/place/6105464/d466ff39-ee07-4e6d-baed-58b1a51c8314.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Central Park 4.5/5(3 reviews) Enjoy the volcano viewpoints and explore Central Park, a lovely green space in Antigua Guatemala. Discover the area's shops or seek out its local tours. [](https://expedia.co.uk/Central-Park-Antigua-Guatemala.d6105464.Attraction) ![Recent trip to Antigua, Guatemala.](https://images.trvl-media.com/place/180589/2b05b9ea-3f0a-4375-9661-84349dc65ef7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Catalina Arch 4.5/5(2 reviews) Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this romantic area. [](https://expedia.co.uk/Santa-Catalina-Arch-Antigua-Guatemala.d553248621532619480.Attraction) ![ Traditional vase and jar at market in Antigua, Guatemala.](https://images.trvl-media.com/place/553248621532963883/3ec95ff3-7959-4920-bfc4-dfcbe0674a2f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Antigua Market 5/5(2 reviews) During your trip to Antigua Guatemala, you can enjoy retail therapy at Antigua Market. Discover the volcano viewpoints in this family-friendly area or enjoy its local tours. [](https://expedia.co.uk/Antigua-Market-Antigua-Guatemala.d553248621532963883.Attraction) ![A one of a kind facade ](https://images.trvl-media.com/place/180589/12305006-65ce-4369-af37-4e05b1482005.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### La Merced Church 5/5(1 review) After visiting La Merced Church, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's shops or seek out its local tours. [](https://expedia.co.uk/La-Merced-Church-Antigua-Guatemala.d6105472.Attraction) ![Cerro de la Cruz Antigua Guatemala](https://images.trvl-media.com/place/553248635975478041/72941465-dbed-49b1-8a26-b0c021969c22.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Cerro de La Cruz You can find out about the history of Antigua Guatemala with a trip to Cerro de La Cruz. Discover the area's volcano viewpoints or seek out its local tours. [](https://expedia.co.uk/Cerro-De-La-Cruz-Antigua-Guatemala.d553248635975478041.Attraction) ### Things to do ![Lake Atitlan One Day Tour from Antigua ](https://mediaim.expedia.com/localexpert/5161783/fbc9ae19-a179-45fb-826d-e1f37c02aa03.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Lake Atitlan One Day Tour from Antigua £67 per adult **80%** of travellers recommend [](https://expedia.co.uk/things-to-do/lake-atitlan-one-day-tour-from-antigua.a5161783.activity-details) ![Antigua: ATV Guided Sunset Tour](https://mediaim.expedia.com/localexpert/48070707/8c6c8cbf-7de5-420d-9021-6857de969452.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Antigua: ATV Guided Sunset Tour £47 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/antigua-atv-guided-sunset-tour.a48070707.activity-details) ![Picture 5 for Activity From Antigua: Pacaya Volcano Trek](https://mediaim.expedia.com/localexpert/4752068/1c69856b-8dcc-4431-92dc-9f40f7df8804.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### From Antigua: Pacaya Volcano Trek £17 per adult **92%** of travellers recommend [](https://expedia.co.uk/things-to-do/from-antigua-pacaya-volcano-trek.a4752068.activity-details) ![Viewpoint](https://mediaim.expedia.com/localexpert/1353381/e7e07cdc-9932-487a-b2c2-c9429a7614fe.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Lake Atitlan Day Tour From Antigua £95 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/lake-atitlan-day-tour-from-antigua.a1353381.activity-details) ![Mold around 120g of chocolates](https://mediaim.expedia.com/localexpert/1349162/80885578-3970-4da0-85f9-47374a6580ca.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Bean-to-Bar Chocolate Workshop in ChocoMuseo Antigua £24 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/bean-to-bar-chocolate-workshop-in-chocomuseo-antigua.a1349162.activity-details) ![Overnight Adventure !!Hike Acatenango Volcano ](https://mediaim.expedia.com/localexpert/2879443/13771bb6-e4a8-43ea-b7b1-62cd435aaf4d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Overnight Adventure Hike Acatenango Volcano £62 per adult [](https://expedia.co.uk/things-to-do/overnight-adventure-hike-acatenango-volcano.a2879443.activity-details) [See all activities in Antigua Guatemala](https://expedia.co.uk/Things-To-Do-In-Antigua-Guatemala.d180589.Travel-Guide-Activities) --- ## Top hotels in Santa Ana ![Casa Buho B&B](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/2c2e8198_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Casa Buho B&B 77 Calle del Agua Antigua Guatemala Guatemala £59 3 Mar - 4 Mar includes taxes & fees Stay at this hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and daily housekeeping. Popular attractions Casa Santo Domingo Museum and Central Park ... 9/10 Wonderful! (48 reviews) Me encantó el lugar ! Es espectacular un jardín lindísimo, el desayuno excelente y la atención de igual manera definitivamente volvería Reviewed on 19 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=03%2F03%2F2026&endDate=04%2F03%2F2026&selected=91818768&PinnedHotelID=91818768&HadPinnedHotel=true®ionId=553248635975847775) ![Barceló Guatemala City](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/78fae458_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Barceló Guatemala City 7 Avenida 15-45, Zona 9 Guatemala City Guatemala £79 3 Mar - 4 Mar includes taxes & fees Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ... 9/10 Wonderful! (3,190 reviews) Nice hotel, centrico y buena comida Reviewed on 12 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=03%2F03%2F2026&endDate=04%2F03%2F2026&selected=2495&PinnedHotelID=2495&HadPinnedHotel=true®ionId=553248635975847775) ![Porta Hotel Antigua](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/b3d7f8e6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Porta Hotel Antigua 8va Calle Poniente No1 Antigua Guatemala Sacatepequez Fully refundableReserve now, pay when you stay £155 18 Feb - 19 Feb includes taxes & fees Stay at this luxury hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the clean rooms ... 9.2/10 Wonderful! (1,007 reviews) Lovely Reviewed on 9 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=18%2F02%2F2026&endDate=19%2F02%2F2026&selected=5545&PinnedHotelID=5545&HadPinnedHotel=true®ionId=553248635975847775) ![Hotel Museo Spa Casa Santo Domingo](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/20929971_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Museo Spa Casa Santo Domingo 3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez £247 24 Feb - 25 Feb includes taxes & fees Stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa and 2 restaurants. Our guests praise the helpful staff and the property ... 9.2/10 Wonderful! (1,040 reviews) Absolutely outstanding place. Loved it Reviewed on 8 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=24%2F02%2F2026&endDate=25%2F02%2F2026&selected=1246555&PinnedHotelID=1246555&HadPinnedHotel=true®ionId=553248635975847775) ![Wyndham Garden Guatemala City](https://images.trvl-media.com/lodging/1000000/30000/26600/26567/449c3cd0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Wyndham Garden Guatemala City 1a Avenida 12-46 Zona 10 Guatemala City Guatemala £93 8 Mar - 9 Mar includes taxes & fees Stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ... 9/10 Wonderful! (1,685 reviews) Excellent staff Reviewed on 5 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=08%2F03%2F2026&endDate=09%2F03%2F2026&selected=26567&PinnedHotelID=26567&HadPinnedHotel=true®ionId=553248635975847775) ![Hotel Camino Real Antigua](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/17346378_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Camino Real Antigua 7a Calle Poniente 33B Antigua Guatemala Sacatepequez £168 1 Mar - 2 Mar includes taxes & fees Stay at this spa hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ... 9.6/10 Exceptional! (1,003 reviews) Good Reviewed on 8 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=01%2F03%2F2026&endDate=02%2F03%2F2026&selected=3084914&PinnedHotelID=3084914&HadPinnedHotel=true®ionId=553248635975847775) [See all 1,186 properties in Santa Ana](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=13%2F02%2F2026&endDate=14%2F02%2F2026®ionId=553248635975847775) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=DX-NH_SPRING_PROMO_553248635975847775) ## Check Santa Ana hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=2026-02-12&endDate=2026-02-13)[12 Feb - 13 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=2026-02-12&endDate=2026-02-13) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=2026-02-13&endDate=2026-02-14)[13 Feb - 14 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=2026-02-13&endDate=2026-02-14) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[13 Feb - 15 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026)[20 Feb - 22 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975847775&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026) --- ### Other neighbourhoods around Santa Ana ![Cross and Volcan de Agua View From Cerro de la Cruz, Antigua, Sacatepequez Department, Guatemala](https://images.trvl-media.com/place/911356092010033152/29d5145e-703b-47ae-817d-6e4cfbcb485c.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Barrio de La Concepción While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum. [](https://expedia.co.uk/Antigua-Guatemala-Barrio-De-La-Concepcion.dx911356092010033152) ![Vue du volcan de Fuego](https://images.trvl-media.com/place/180589/dca320f5-d6f0-40d9-9f12-90c9c1ede687.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Historic Center If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing. [](https://expedia.co.uk/Antigua-Guatemala-Historic-Center.dx911355684795535360) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Santa Ana Travel Guide ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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