Sant'Antonio Holidays from £313

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Your SantAntonio Holiday

Reserve a SantAntonio holiday package and prepare to experience all this lively city has to offer. Consider staying in the neighbourhood of Vecchiano, which is great for bars and pubs, walking and nature. Fill your spare time with visits to Cathedral of Pisa, Knights Square and Pisa Baptistry, some of the things you should see during your trip to SantAntonio. A couple of clicks is all it takes to put together the perfect SantAntonio holiday on Expedia.

Top Sant'Antonio Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Ginori al DUOMO

Hotel Ginori al DUOMO

Historic Centre of Florence
Save 100% on your flight
£313
per person
29 Nov - 4 Dec
found 18 hours ago
Return direct flight included
Edinburgh (EDI) to Florence (FLR)
8.8/10 Excellent! (61 reviews)
Fantastic stay, thank you for the upgrade, spacious, cool rooms. Great location, walk to the station and across the road is a convenience store and great restaurants and gelato in the same street

Reviewed on 4 Sept 2026

The Moon Boutique Hotel & Spa

The Moon Boutique Hotel & Spa

Historic Centre of Florence
Save 100% on your flight
£407
per person
29 Nov - 4 Dec
found 18 hours ago
Return direct flight included
Edinburgh (EDI) to Florence (FLR)
9.6/10 Exceptional! (592 reviews)
Great location. We suggest taking the river down to the city center every day. The free breakfast and coffee is great way to start your day. Schedule a spa day at least once so you can relax before the walk to dinner! Reception was super nice and even helped us call a taxi.

Reviewed on 21 Sept 2026

Hotel La Scaletta Al Ponte Vecchio

Hotel La Scaletta Al Ponte Vecchio

Historic Centre of Florence
Save 100% on your flight
£432
per person
29 Nov - 4 Dec
found 18 hours ago
Return direct flight included
Edinburgh (EDI) to Florence (FLR)
9/10 Wonderful! (1,005 reviews)
L'Andana

L'Andana

Save 100% on your flight
£1,132
per person
24 Oct - 31 Oct
found 23 hours ago
Return flight included
London (LON) to Florence (FLR)
9.6/10 Exceptional! (94 reviews)
Excellent place

Reviewed on 9 Sept 2026

Grand Hotel Cavour

Grand Hotel Cavour

Historic Centre of Florence
Save 100% on your flight
£419
per person
29 Nov - 4 Dec
found 18 hours ago
Return direct flight included
Edinburgh (EDI) to Florence (FLR)
9.2/10 Wonderful! (1,004 reviews)

SantAntonio Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Galileo Galilei Airport (PSA)
Max Temp Winter
10ºC
Max Temp Summer
27ºC
Top Sights
Cathedral of Pisa, Calambrone Beach and Palazzo Blu

Top hotels in Sant'Antonio

Hotel Bologna

Hotel Bologna

Via Mazzini 57 Pisa PI
Fully refundableReserve now, pay when you stay
£99
25 Oct - 26 Oct
includes taxes & fees
Hotel Bologna
Max Hotel Livorno

Max Hotel Livorno

Via Giotto Ciardi, 28 Livorno LI
Fully refundableReserve now, pay when you stay
£67
18 Oct - 19 Oct
includes taxes & fees
8.6/10 Excellent! (1,001 reviews)
"Rooms were good. All television channels are in Italian if you are someone who doesn’t speak the language and wants to watch TV. There’s a nice big window that opens up so you can get fresh air however there’s no outdoor space so we personally felt trapped inside the hotel room, especially considering ..."

Reviewed on 7 Aug 2026

Max Hotel Livorno
Grand Hotel Duomo

Grand Hotel Duomo

Via Santa Maria 94 Pisa PI
£127
28 Sept - 29 Sept
includes taxes & fees
8.6/10 Excellent! (1,060 reviews)
"I’d describe the hotel as “no frills”, but in fairness you get what you pay for. Breakfast is also basic too- not even a toaster. Pastries are plentiful so if you’re sweet toothed - fill your boots. The location for the tower and duomo however could not be better. Staff are polite and helpful and ..."

Reviewed on 23 Sept 2026

Grand Hotel Duomo
See all 6,410 properties in Sant'Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Sant'Antonio attractions

A river with buildings along its banks, a prominent church with a spire, and a mountain in the background.

Church of Santa Maria della Spina

9.4/10 (6 reviews)
In a city of remarkable architecture, this Gothic church on the River Arno is considered to be one of Pisa’s most impressive structures despite its small size.
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A historic building with a sign reading "DOM ETSCHRISTINA VETM DICATUM" and a colorful banner for "WANDY WARHOL".

Palazzo Blu

8.8/10 (26 reviews)
Explore this time capsule of classic Pisan life and learn about the achievements of this fascinating town’s most creative sons and daughters.
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A historic building with arched walkways, palm trees, and a flag on top.

Giardino Scotto

9.4/10 (3 reviews)
Explore the great outdoors at Giardino Scotto, a lovely green space in Sant'Antonio. Stroll along the riverfront in this culturally rich area or visit its lively bars.
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Piazza Vittorio Emanuele II

You can learn about the history of Sant'Antonio with a visit to Piazza Vittorio Emanuele II. Stroll along the riverfront in this culturally rich area or visit its lively bars.
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Saint Cristina Church

Saint Cristina Church is just one of the places to see in Sant'Antonio, so why not enjoy the other things to explore during your travels? Visit the stunning cathedral and lively bars in this culturally rich area.
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Santo Sepolcro

Learn about the local history of Sant'Antonio with a stop at Santo Sepolcro. Visit the stunning cathedral and lively bars in this culturally rich area.
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Tuttomondo

Learn about the local history of Sant'Antonio with a stop at Tuttomondo. Amble around this culturally rich area's riverfront and enjoy its lively bars.
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San Martino Church

San Martino Church is just one of the places to see in Sant'Antonio, so why not enjoy the other things to explore during your travels? Visit the stunning cathedral and lively bars in this culturally rich area.
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What to do in Sant'Antonio

From Livorno: Bus Transfer to the Leaning Tower of Pisa

From Livorno: Bus Transfer to the Leaning Tower of Pisa

£18
per adult
84% of travellers recommend
From Livorno: Bus Transfer to the Leaning Tower of Pisa
From La Spezia: Shore Excursion to Pisa

From La Spezia: Shore Excursion to Pisa

£33
per adult
94% of travellers recommend
From La Spezia: Shore Excursion to Pisa
From Livorno: Shore Excursion to Florence and Pisa

From Livorno: Shore Excursion to Florence and Pisa

£30
per adult
84% of travellers recommend
From Livorno: Shore Excursion to Florence and Pisa
See all activities in Sant'Antonio

Frequently asked questions

Why should I book my SantAntonio holiday with Expedia?
Expedia has your back for every detail of your SantAntonio getaway. You'll always land the best deals, but when you bundle your accommodation, flights and/or hire car into a holiday package, you'll get even more savings. Want to really make the most of your stay? Add some activities and tours to your customised package. Expedia offers flexible cancellation policies on almost all bookings, so there's no need to worry if your plans change. Head over to our Customer Service Portal link to learn more.
When is the best time of year to holiday in SantAntonio?
If you enjoy the buzz of peak season, head to SantAntonio in April, May and August. If you'd like a calmer vibe, October, November and December will suit you better. To give you an idea of what type of weather to expect, the daytime average temperature in January, the coolest time of year in SantAntonio, is 7ºC. The warmest period here is July, when temperatures average 24ºC.
What is the top hotel for my holiday in SantAntonio?
Kick back and relax in SantAntonio by choosing Grand Hotel Duomo as your gateway to adventure and exploration.
How do I get a cheap holiday to SantAntonio?
Creating your own SantAntonio holiday with Expedia is a smart way to save. We offer access to over 400 partner airlines and 321,000 hotels around the world. With such an extensive range to select from, you'll have no difficulty creating your dream adventure. Learn more about how you can save money on your next holiday when you combine your hotel and flight bookings with Expedia.
What should I do on my SantAntonio holiday?
Make sure your holiday in SantAntonio is an unforgettable one by taking in its best attractions. Cathedral of Pisa, Pisa Baptistry, Church of Santa Maria della Spina and Knights Square are some of the things we recommend seeing while you're in this city.
What is the best area to stay in when on holiday in SantAntonio?
SantAntonio has plenty of interesting places to see, such as Santo Sepolcro. Stay somewhere close by and make sightseeing easier.
Do I need a visa for my SantAntonio holiday?
Official government websites will have all the information you need on visa requirements, application procedures and any supporting documentation. Your nationality and reason for travelling, whether it be for work or holidays, will determine if you need a visa for SantAntonio. Also be sure that your passport is up to date and has at least six months validity remaining beyond your return date. Finalise all your travel planning well in advance to avoid any last-minute surprises.
What should I wear on my SantAntonio holiday?
Do some research into the sorts of things people in SantAntonio wear, and maybe even check out style blogs for some fashion tips. Aim to create a versatile wardrobe filled with pieces that work for your destination and show off your unique sense of style. Be sure to check the local weather forecast so you can pack accordingly. The warmest time of year in SantAntonio is July, with average daytime temperatures of 24ºC. If you're on holiday in the coolest month of January, the mercury hovers around 7ºC during the day.
What does an Expedia SantAntonio holiday include?
Flights, hire cars and hotels — you'll find them all here. With Expedia, you can create your SantAntonio package the way you like it. All you have to do is work out what you need. Once you've made your booking, why not add extras like experiences and activities? The more you bundle, the bigger your savings! Apartments and villas are a couple of the most sought-after property types in SantAntonio. Whatever your group size or holiday style, you can rely on Expedia for the flexibility to customise your escape.
Does Expedia offer Book Now, Pay Later SantAntonio holidays?
Your bank balance shouldn't stop you from taking a holiday, so Expedia has come up with a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book a dream getaway without exhausting your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your break. Check out these flexible payment options:
  • Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's convenient payment plans. If paying across multiple transactions works for you, choose this option during the checkout process.
  • No-deposit holidays: Pressing the "book now" button is much easier with this option. With no deposit required for your escape, you can Book Now, Pay Later and start packing your bags.
Can I choose my airline with a SantAntonio Expedia holiday?
Yes — and it's simple too. Expedia has access to more than 400 partner airlines around the world. Our packages give you the flexibility to pick from available flight, hotel or activity options that suit you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.