Sant'Antonio Holidays from £314

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Your SantAntonio Holiday

Reserve a SantAntonio holiday package and prepare to experience all this lively city has to offer. Consider staying in the neighbourhood of Vecchiano, which is great for bars and pubs, walking and nature. Fill your spare time with visits to Cathedral of Pisa, Knights Square and Pisa Baptistry, some of the things you should see during your trip to SantAntonio. A couple of clicks is all it takes to put together the perfect SantAntonio holiday on Expedia.

Top Sant'Antonio Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
The Moon Boutique Hotel & Spa

The Moon Boutique Hotel & Spa

Historic Centre of Florence
Save 100% on your flight
£314
per person
30 Oct - 2 Nov
found 1 day ago
Return flight included
Birmingham (BHX) to Florence (FLR)
9.6/10 Exceptional! (580 reviews)
Stunning hotel and maintained to a spotless standard. Bit of a trek to the centre and parking not cheap but good services just outside (tram, bus) - just takes some working out. We probably didn't need to go for the suite considering the time of year (Sauna and jacuzzi not overly used after stomping streets in near 40deg heat!). Breakfast good and staff super friendly/informative.

Reviewed on 11 Aug 2026

Eden Rock Resort

Eden Rock Resort

£653
per person
5 Oct - 9 Oct
found 1 day ago
Return flight included
London (LCY) to Florence (FLR)
9.8/10 Exceptional! (109 reviews)
This was a beautiful property about 10 mins away from Florence. You get the beauty of Tuscany without having to go too far. The hotel only has 12 rooms and everyone knows you by name. We traveled with 2 kids and the rooms were very spacious. Staff are wonderful, Onsite restaurant was great. Views were breathtaking. We didn't have a car, and the hotel was able to help us with cabs easily. Service was excellent and we would highly recommend this hotel!

Reviewed on 18 Jul 2026

Aurum Uffizi

Aurum Uffizi

Historic Centre of Florence
Save 100% on your flight
£459
per person
26 Oct - 30 Oct
found 2 hours ago
Return direct flight included
Edinburgh (EDI) to Florence (FLR)
7.6/10 Good! (1,003 reviews)
Clean room, convenient location. has AC and lift. Breakfast was ok. Would stay again

Reviewed on 12 Aug 2026

Eurostars Florence Boutique

Eurostars Florence Boutique

Historic Centre of Florence
Save 100% on your flight
£602
per person
26 Oct - 30 Oct
found 2 hours ago
Return direct flight included
Edinburgh (EDI) to Florence (FLR)
8.6/10 Excellent! (497 reviews)
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Reviewed on 10 Aug 2026

Aurum Firenze

Aurum Firenze

Historic Centre of Florence
Save 100% on your flight
£458
per person
16 Oct - 19 Oct
found 1 day ago
Return direct flight included
Birmingham (BHX) to Florence (FLR)
7.4/10 Good! (1,008 reviews)
Room very small, no chairs inside, ants everywhere, including the breakfast area. Quadruple room has a double bed and a single bed, apparently this was the biggest room in the hotel. We book for 4 people ( 2 adults and 2 children 12 and 16 and they had to squeeze in a single bed.

Reviewed on 12 Aug 2026

SantAntonio Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Galileo Galilei Airport (PSA)
Max Temp Winter
10ºC
Max Temp Summer
27ºC
Top Sights
Cathedral of Pisa, Calambrone Beach and Palazzo Blu

Top hotels in Sant'Antonio

Hotel Bologna

Hotel Bologna

Via Mazzini 57 Pisa PI
Fully refundableReserve now, pay when you stay
£100
31 Aug - 1 Sept
includes taxes & fees
8.8/10 Excellent! (1,009 reviews)
"Hotel is quite old fashioned air con not great given the extreme temperatures."

Reviewed on 19 Aug 2026

Hotel Bologna
Max Hotel Livorno

Max Hotel Livorno

Via Giotto Ciardi, 28 Livorno LI
Fully refundableReserve now, pay when you stay
£62
20 Sept - 21 Sept
includes taxes & fees
8.6/10 Excellent! (1,002 reviews)
"Rooms were good. All television channels are in Italian if you are someone who doesn’t speak the language and wants to watch TV. There’s a nice big window that opens up so you can get fresh air however there’s no outdoor space so we personally felt trapped inside the hotel room, especially considering ..."

Reviewed on 7 Aug 2026

Max Hotel Livorno
Sina Astor

Sina Astor

Viale Giosue' Carducci, 54 Viareggio LU
Fully refundableReserve now, pay when you stay
£161
20 Sept - 21 Sept
includes taxes & fees
Sina Astor
See all 6,450 properties in Sant'Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Sant'Antonio attractions

A river with buildings along its banks, a prominent church with a spire, and a mountain in the background.

Church of Santa Maria della Spina

9.4/10 (6 reviews)
In a city of remarkable architecture, this Gothic church on the River Arno is considered to be one of Pisa’s most impressive structures despite its small size.
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A street with a church and a blue building with a Andy Warhol exhibit.

Palazzo Blu

8.8/10 (26 reviews)
Explore this time capsule of classic Pisan life and learn about the achievements of this fascinating town’s most creative sons and daughters.
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Piazza Vittorio Emanuele II

You can learn about the history of Sant'Antonio with a visit to Piazza Vittorio Emanuele II. Stroll along the riverfront in this culturally rich area or visit its lively bars.
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Santo Sepolcro

Learn about the local history of Sant'Antonio with a stop at Santo Sepolcro. Visit the stunning cathedral and lively bars in this culturally rich area.
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Saint Cristina Church

Saint Cristina Church is just one of the places to see in Sant'Antonio, so why not enjoy the other things to explore during your travels? Visit the stunning cathedral and lively bars in this culturally rich area.
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San Martino Church

San Martino Church is just one of the places to see in Sant'Antonio, so why not enjoy the other things to explore during your travels? Visit the stunning cathedral and lively bars in this culturally rich area.
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Arsenale Cinema

Get tickets for a show at Arsenale Cinema, a popular theatre in Sant'Antonio. Stroll along the riverfront in this culturally rich area or visit its lively bars.
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Tuttomondo

Learn about the local history of Sant'Antonio with a stop at Tuttomondo. Amble around this culturally rich area's riverfront and enjoy its lively bars.
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What to do in Sant'Antonio

From Livorno: Bus Transfer to the Leaning Tower of Pisa

From Livorno: Bus Transfer to the Leaning Tower of Pisa

£18
per adult
84% of travellers recommend
From Livorno: Bus Transfer to the Leaning Tower of Pisa
From La Spezia: Shore Excursion to Pisa

From La Spezia: Shore Excursion to Pisa

£33
per adult
94% of travellers recommend
From La Spezia: Shore Excursion to Pisa
From Livorno: Shore Excursion to Florence and Pisa

From Livorno: Shore Excursion to Florence and Pisa

£30
per adult
82% of travellers recommend
From Livorno: Shore Excursion to Florence and Pisa
See all activities in Sant'Antonio

Frequently asked questions

Why should I book my SantAntonio holiday with Expedia?
Expedia has your back for every detail of your SantAntonio getaway. You'll always land the best deals, but when you bundle your accommodation, flights and/or hire car into a holiday package, you'll get even more savings. Want to really make the most of your stay? Add some activities and tours to your customised package. Expedia offers flexible cancellation policies on almost all bookings, so there's no need to worry if your plans change. Head over to our Customer Service Portal link to learn more.
When is the best time of year to holiday in SantAntonio?
If you enjoy the buzz of peak season, head to SantAntonio in April, May and August. If you'd like a calmer vibe, October, November and December will suit you better. To give you an idea of what type of weather to expect, the daytime average temperature in January, the coolest time of year in SantAntonio, is 7ºC. The warmest period here is July, when temperatures average 24ºC.
What is the top hotel for my holiday in SantAntonio?
Kick back and relax in SantAntonio by choosing Grand Hotel Duomo as your gateway to adventure and exploration.
How do I get a cheap holiday to SantAntonio?
Creating your own SantAntonio holiday with Expedia is a smart way to save. We offer access to over 400 partner airlines and 321,000 hotels around the world. With such an extensive range to select from, you'll have no difficulty creating your dream adventure. Learn more about how you can save money on your next holiday when you combine your hotel and flight bookings with Expedia.
What should I do on my SantAntonio holiday?
Make sure your holiday in SantAntonio is an unforgettable one by taking in its best attractions. Cathedral of Pisa, Pisa Baptistry, Church of Santa Maria della Spina and Knights Square are some of the things we recommend seeing while you're in this city.
What is the best area to stay in when on holiday in SantAntonio?
SantAntonio has plenty of interesting places to see, such as Santo Sepolcro. Stay somewhere close by and make sightseeing easier.
Do I need a visa for my SantAntonio holiday?
Official government websites will have all the information you need on visa requirements, application procedures and any supporting documentation. Your nationality and reason for travelling, whether it be for work or holidays, will determine if you need a visa for SantAntonio. Also be sure that your passport is up to date and has at least six months validity remaining beyond your return date. Finalise all your travel planning well in advance to avoid any last-minute surprises.
What should I wear on my SantAntonio holiday?
Do some research into the sorts of things people in SantAntonio wear, and maybe even check out style blogs for some fashion tips. Aim to create a versatile wardrobe filled with pieces that work for your destination and show off your unique sense of style. Be sure to check the local weather forecast so you can pack accordingly. The warmest time of year in SantAntonio is July, with average daytime temperatures of 24ºC. If you're on holiday in the coolest month of January, the mercury hovers around 7ºC during the day.
What does an Expedia SantAntonio holiday include?
Flights, hire cars and hotels — you'll find them all here. With Expedia, you can create your SantAntonio package the way you like it. All you have to do is work out what you need. Once you've made your booking, why not add extras like experiences and activities? The more you bundle, the bigger your savings! Apartments and villas are a couple of the most sought-after property types in SantAntonio. Whatever your group size or holiday style, you can rely on Expedia for the flexibility to customise your escape.
Does Expedia offer Book Now, Pay Later SantAntonio holidays?
Your bank balance shouldn't stop you from taking a holiday, so Expedia has come up with a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book a dream getaway without exhausting your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your break. Check out these flexible payment options:
  • Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's convenient payment plans. If paying across multiple transactions works for you, choose this option during the checkout process.
  • No-deposit holidays: Pressing the "book now" button is much easier with this option. With no deposit required for your escape, you can Book Now, Pay Later and start packing your bags.
Can I choose my airline with a SantAntonio Expedia holiday?
Yes — and it's simple too. Expedia has access to more than 400 partner airlines around the world. Our packages give you the flexibility to pick from available flight, hotel or activity options that suit you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.