Title: TOP Business Hotels in Sant'Antioco Island for 2026 | Expedia.co.uk [Sant'Antioco Island Travel Guide](https://expedia.co.uk/SantAntioco-Island.dx6182342)[Hotels in Sant'Antioco Island](https://expedia.co.uk/SantAntioco-Island-Hotels.d6182342.Travel-Guide-Hotels)[Holiday Rentals in Sant'Antioco Island](https://expedia.co.uk/SantAntioco-Island-Holiday-Rentals.d6182342.Travel-Guide-HolidayRentals)[Flights to Sant'Antioco Island](https://expedia.co.uk/Cheap-Flights-To-SantAntioco-Island.d6182342.Travel-Guide-Flights)[Sant'Antioco Island Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-SantAntioco-Island.d6182342.Car-Hire-Guide)[Sant'Antioco Island Holidays](https://expedia.co.uk/SantAntioco-Island.d6182342.Holidays-City-Breaks) ![An island Sant’Antioco where already beauty reigns Sardegna will always be full of beautiful nature to discover and am discovering it.](https://images.trvl-media.com/place/6345589/73b0c4d0-d6f7-4bf0-8ccd-48933700a363.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Pamela Ekundayo ![](https://images.trvl-media.com/place/6345589/73b0c4d0-d6f7-4bf0-8ccd-48933700a363.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sant'Antioco Island Business Hotels Tonight [16 Jan - 17 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6182342&startDate=2026-01-16&endDate=2026-01-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [17 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6182342&startDate=2026-01-17&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6182342&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6182342&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Sant'Antioco Island business-friendly hotels ![Property entrance](https://images.trvl-media.com/lodging/22000000/21490000/21487900/21487805/8f018da4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/22000000/21490000/21487900/21487805/be418b05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/22000000/21490000/21487900/21487805/9e15c0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/22000000/21490000/21487900/21487805/7468c8ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel I Colori [](https://www.expedia.co.uk/SantAntioco-Hotels-Hotel-I-Colori.h21487805.Hotel-Information) Sant'Antioco 8.8/10 Excellent (25 reviews) "Questa è una piccola struttura a conduzione familiare. La colazione era piuttosto buona. C'era un grazioso cortile antistante. Sì, hanno un piccolo parcheggio, ma ho dovuto parcheggiare in strada. Per entrare nella struttura e nella camera servivano tre chiavi separate, e ho avuto difficoltà a far funzionare la chiave della mia camera, quindi non sono uscita per cena per paura di rimanere chiusa fuori, dato che ero una donna che viaggiava da sola." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa £55 includes taxes & fees 17 Jan - 18 Jan [](https://www.expedia.co.uk/SantAntioco-Hotels-Hotel-I-Colori.h21487805.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/6000000/5620000/5616800/5616764/7ce31cd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/6000000/5620000/5616800/5616764/6a6d3090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/6000000/5620000/5616800/5616764/99b7ce99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/6000000/5620000/5616800/5616764/ce998fe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lu' Hotel [](https://www.expedia.co.uk/Carbonia-Hotels-Lu-Hotel.h5616764.Hotel-Information) Carbonia 8.8/10 Excellent (280 reviews) "Lovely stay" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Pheobe [](https://www.expedia.co.uk/Carbonia-Hotels-Lu-Hotel.h5616764.Hotel-Information) ![Double Room | Beach/ocean view](https://images.trvl-media.com/lodging/13000000/12100000/12091400/12091393/ab1f01e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/13000000/12100000/12091400/12091393/41d777bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12100000/12091400/12091393/bf86cab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/13000000/12100000/12091400/12091393/f967bc8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### B&B Sa Cruxitta [](https://www.expedia.co.uk/Portoscuso-Hotels-BB-Sa-Cruxitta.h12091393.Hotel-Information) Portoscuso 9.0/10 Wonderful (17 reviews) "This was the worse hotel/bnb experience of our lives and we've stayed in 100s of places. No one was there to greet us. We called and over the phone they told us to go in the house and find a room. The doors were open for anyone on the street to walk in. It was raining and water was coming in thru the open doors which we spent 15 minutes cleaning up. Then these unfriendly rough-looking guys showed up, day-laborers using this is a boarding house/squat. None of them were wearing masks and they were... ![Ireland](https://a.travel-assets.com/egds/marks/flags/ie.svg) Derek £57 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Portoscuso-Hotels-BB-Sa-Cruxitta.h12091393.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/43000000/42490000/42484100/42484001/8d6ae468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/43000000/42490000/42484100/42484001/edb90e22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, Non Smoking, Garden View (The Suite) | Individually decorated, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/43000000/42490000/42484100/42484001/c65602c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/43000000/42490000/42484100/42484001/b2972be5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Le Calle [](https://www.expedia.co.uk/Iglesias-Hotels-Le-Calle.h42484001.Hotel-Information) Iglesias 8.4/10 Very good (7 reviews) "Leider ist die Unterkunft unauffinbar wir standen in der Pampa vor einem geschlossenen Eisentor. Der Garten sah verwahrlost aus und Haus haben wir keines gesehen. So sind wir wieder abgefahren, da wir auch keine Telefonnummer gefunden haben. Schade ums Geld." ![Switzerland](https://a.travel-assets.com/egds/marks/flags/ch.svg) Jacqueline £56 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Iglesias-Hotels-Le-Calle.h42484001.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/4000000/3390000/3385900/3385828/d3c31c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3390000/3385900/3385828/6894b8d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/4000000/3390000/3385900/3385828/79098d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/4000000/3390000/3385900/3385828/ef8a8c2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Don Pedro [](https://www.expedia.co.uk/Portoscuso-Hotels-Hotel-Don-Pedro.h3385828.Hotel-Information) Portoscuso 8.2/10 Very good (56 reviews) "Very kind staff, however the hotel is pretty old and needs to be updated. " ![Italy](https://a.travel-assets.com/egds/marks/flags/it.svg) Laura [](https://www.expedia.co.uk/Portoscuso-Hotels-Hotel-Don-Pedro.h3385828.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39210000/39203100/39203025/e4f7a3a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast (EUR 5 per person)](https://images.trvl-media.com/lodging/40000000/39210000/39203100/39203025/82c314bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room | Down duvets, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/40000000/39210000/39203100/39203025/5110b8bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down duvets, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/40000000/39210000/39203100/39203025/3448e828.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Agriturismo Sogno Latino [](https://www.expedia.co.uk/Iglesias-Hotels-Agriturismo-Sogno-Latino.h39203025.Hotel-Information) Iglesias 8.0/10 Very good (1 review) "Gestore accogliente e professionale ottima colazione silenzio adatto a grandi dormite " ![Italy](https://a.travel-assets.com/egds/marks/flags/it.svg) sergio [](https://www.expedia.co.uk/Iglesias-Hotels-Agriturismo-Sogno-Latino.h39203025.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-30&endDate=2026-01-31®ionId=6182342&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Sant'Antioco Island Hotel Reviews ![Lu' Hotel](https://images.trvl-media.com/lodging/6000000/5620000/5616800/5616764/7ce31cd4_y.jpg) ### Lu' Hotel 10/10 Excellent "Everything about the hotel was excellent - room was clean, all the staff were friendly, polite and very helpful, the food in the restaurant was superb and the breakfast was great." 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[Portopaglietto Beach ](https://www.expedia.co.uk/Portopaglietto-Beach-Sardinia.d6267772.Attraction) - [Portoscuso Spanish Tower ](https://www.expedia.co.uk/Portoscuso-Spanish-Tower-Portoscuso.d6270281.Attraction) - [Portoscuso Holidays ](https://www.expedia.co.uk/Portoscuso.d182144.Holidays-City-Breaks) - [Visit Portoscuso ](https://www.expedia.co.uk/Portoscuso.dx182144) - [Visit San Giovanni Suergiu ](https://www.expedia.co.uk/San-Giovanni-Suergiu.dx6345598) - [San Pietro Island Holidays ](https://www.expedia.co.uk/San-Pietro-Island.d6182344.Holidays-City-Breaks) - [Visit San Pietro Island ](https://www.expedia.co.uk/San-Pietro-Island.dx6182344) - [Sant'antioco Tourist Port ](https://www.expedia.co.uk/SantAntioco-Tourist-Port-SantAntioco.d6274614.Attraction) - [Sant'antioco Holidays ](https://www.expedia.co.uk/SantAntioco.d6035186.Holidays-City-Breaks) - [Spiaggia Grande Holidays ](https://www.expedia.co.uk/Spiaggia-Grande.d6343003.Holidays-City-Breaks) - [Sulcis Iglesiente Holidays ](https://www.expedia.co.uk/Sulcis-Iglesiente.d3000655262.Holidays-City-Breaks) - [Visit Sulcis Iglesiente ](https://www.expedia.co.uk/Sulcis-Iglesiente.dx3000655262) - [Tonnara Su Pranu ](https://www.expedia.co.uk/Tonnara-Su-Pranu-Portoscuso.d756459833267425280.Attraction) - [Visit Tratalias ](https://www.expedia.co.uk/Tratalias.dx6345599) - [Car hire Calasetta ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Calasetta.d6084584.Car-Hire-Guide) - [Car hire Carloforte ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Carloforte.d6049006.Car-Hire-Guide) - [Car hire Portoscuso ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Portoscuso.d182144.Car-Hire-Guide) - [Car hire near San Pietro Island ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Pietro-Island.d6182344.Car-Hire-Guide) - [Car hire Sant'Antioco ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-SantAntioco.d6035186.Car-Hire-Guide) - [Surprice Car Rentals Rental Cars in Sulcis Iglesiente ](https://www.expedia.co.uk/SurPrice-Car-Rentals-Car-Rentals-In-Sulcis-Iglesiente.d3000655262-c1034.Car-Rental-Guide-Suppliers) - 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