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Check prices for these dates

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13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for Sanford USD Medical Center hotels

A spacious bar area with a large TV screen, a fireplace, and a wine rack.

1. Highpoint Hotel

Highpoint Hotel
3.0 star property
University Heights, 0.2 mi from Sanford USD Medical Center
9.6 out of 10, Exceptional, (420 reviews)
"Great place to stay."
United States
Lee
The price is £95
includes taxes & fees
13 Dec - 14 Dec
Highpoint Hotel
A large, two-story building with a stone facade and multiple windows, illuminated by warm lighting.

2. Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls
3.0 star property
Mall District, 1.8 mi from Sanford USD Medical Center
9.6 out of 10, Exceptional, (1,266 reviews)
"Absolutely love staying here.. alway pleasant experience.. we've stayed here at least 10 times"
United States
Nicholas
The price is £152
includes taxes & fees
11 Dec - 12 Dec
Clubhouse Hotel Suites Sioux Falls
A lobby with a large safe, a checkered floor, and a sofa with cushions.

3. Hotel On Phillips

Hotel On Phillips
2.5 star property
Downtown Sioux Falls, 1.1 mi from Sanford USD Medical Center
9.6 out of 10, Exceptional, (1,642 reviews)
"Staff was friendly and the property was clean"
United States
Victoria
The price is £138
includes taxes & fees
24 Nov - 25 Nov
Hotel On Phillips
A patio with wicker chairs and a round table with a fire pit.

4. Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
University Heights, < 0.1 mi from Sanford USD Medical Center
9.4 out of 10, Exceptional, (682 reviews)
"The property was very clean and the staff was great."
United States
Ross
The price is £89
includes taxes & fees
23 Nov - 24 Nov
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
A modern lobby with a glass fireplace, seating areas, and indoor plants.

5. Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown
4.0 star property
Downtown Sioux Falls, 1.5 mi from Sanford USD Medical Center
9.4 out of 10, Exceptional, (294 reviews)
"Great stay super cute location"
United States
Marnie
The price is £129
includes taxes & fees
23 Nov - 24 Nov
Canopy By Hilton Sioux Falls Downtown
A long dining table with chairs, a bar area with bottles, and a brick wall with a chandelier.

6. Hilton Garden Inn Sioux Falls Downtown

Hilton Garden Inn Sioux Falls Downtown
3.0 star property
Downtown Sioux Falls, 1.2 mi from Sanford USD Medical Center
8.8 out of 10, Excellent, (1,000 reviews)
"Great hotel amazing access to the main strip"
United States
Samuel
The price is £101
includes taxes & fees
22 Nov - 23 Nov
Hilton Garden Inn Sioux Falls Downtown
A multi-level hotel lobby with a central seating area, multiple floors, and a variety of amenities including a bar and dining space.

7. Sheraton Sioux Falls Hotel & Convention Center

Sheraton Sioux Falls Hotel & Convention Center
4.0 star property
Northwest Sioux Falls, 1.8 mi from Sanford USD Medical Center
8.6 out of 10, Excellent, (1,000 reviews)
"Clean room friendly staff"
United States
Charmaine
The price is £82
includes taxes & fees
22 Nov - 23 Nov
Sheraton Sioux Falls Hotel & Convention Center
A restaurant interior with a bar area, seating, and a decorative ceiling.

8. Country Inn & Suites by Radisson, Sioux Falls

Country Inn & Suites by Radisson, Sioux Falls
3.0 star property
Downtown Sioux Falls, 1.2 mi from Sanford USD Medical Center
8.4 out of 10, Very good, (1,426 reviews)
"Great stay!"
United States
Hayley
The price is £73
includes taxes & fees
13 Dec - 14 Dec
Country Inn & Suites by Radisson, Sioux Falls
A spacious lobby with multiple seating areas, a bar, and a staircase leading to an upper level.

9. Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG
3.0 star property
Downtown Sioux Falls, 1.1 mi from Sanford USD Medical Center
8.6 out of 10, Excellent, (1,000 reviews)
"Very clean hotel with very helpful and friendly staff."
United States
Chad
The price is £107
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Sioux Falls-City Centre by IHG
A hotel room with two beds, a desk with a computer, a television, and a couch.

10. The Center Inn

The Center Inn
2.5 star property
All Saints, 1.4 mi from Sanford USD Medical Center
8.4 out of 10, Very good, (939 reviews)
"Very nice, basic hotel with great location on the Avera hospital campus."
United States
thomas
The price is £85
includes taxes & fees
13 Dec - 14 Dec
The Center Inn
An indoor pool area with a slide, seating, and tropical decor.

11. Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
3.0 star property
Northwest Sioux Falls, 1.8 mi from Sanford USD Medical Center
7.8 out of 10, Good, (1,659 reviews)
"It was great place to take kids for a mini vacation. They had so much fun . The elevator could’ve been cleaner but overall was a fantastic place to stay"
United States
Peggy
The price is £53
includes taxes & fees
13 Dec - 14 Dec
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
A hotel room with a bed, two bedside lamps, a nightstand, a mirror, and a small desk with a telephone.

12. Valley Inn

Valley Inn
2.5 star property
University Heights, < 0.1 mi from Sanford USD Medical Center
8.0 out of 10, Very good, (1,000 reviews)
"It was close to the airport and lots of places to eat. The rooms were spacious and comfortable."
United States
Doreen
The price is £78
includes taxes & fees
13 Dec - 14 Dec
Valley Inn
A reception area with a marble counter, a black office chair, and a potted plant.

13. Sioux Falls Inn

Sioux Falls Inn
2.0 star property
Northwest Sioux Falls, 1.9 mi from Sanford USD Medical Center
5.8 out of 10, (10 reviews)
"A lot of remodeling going on throughout the place, so yes. A lot of debris and new furniture waiting ro be put in."
United States
Maria
The price is £37
includes taxes & fees
16 Nov - 17 Nov
Sioux Falls Inn
A reception area with a counter, a food mart sign, and a security camera.

14. Ramada by Wyndham Sioux Falls

Ramada by Wyndham Sioux Falls
2.0 star property
1.7 mi from Sanford USD Medical Center
5.8 out of 10, (1,000 reviews)
"Great hotel!! Great customer service and my room was cleaned each day! Enjoy breakfast too!"
United States
Jonathan Robert
The price is £47
includes taxes & fees
23 Nov - 24 Nov
Ramada by Wyndham Sioux Falls
A spacious lobby with a central seating area, a reception desk, and a large window providing natural light.

15. Staybridge Suites Sioux Falls Southwest by IHG

Staybridge Suites Sioux Falls Southwest by IHG
3.0 star property
South Sioux Falls, 3.3 mi from Sanford USD Medical Center
9.6 out of 10, Exceptional, (558 reviews)
"Good clean rooms with comfortable beds and a good breakfast spread."
United States
Bailey
The price is £88
includes taxes & fees
22 Nov - 23 Nov
Staybridge Suites Sioux Falls Southwest by IHG
A swimming pool with clear blue water, surrounded by a tiled deck and a seating area with chairs and tables.

16. Comfort Inn & Suites at Sanford Sports Complex

Comfort Inn & Suites at Sanford Sports Complex
2.5 star property
Northwest Sioux Falls, 3.7 mi from Sanford USD Medical Center
9.6 out of 10, Exceptional, (1,240 reviews)
"Great place, with friendly staff."
United States
Kristine
The price is £84
includes taxes & fees
22 Nov - 23 Nov
Comfort Inn & Suites at Sanford Sports Complex
A modern hotel lobby with seating areas, a bar, and a kitchen visible in the background.

17. Hampton Inn & Suites Southwest/Sioux Falls

Hampton Inn & Suites Southwest/Sioux Falls
2.5 star property
South Sioux Falls, 3.5 mi from Sanford USD Medical Center
9.4 out of 10, Exceptional, (1,000 reviews)
"The bed was extremely comfortable, the room very clean and staff were very helpful!"
United States
Elizabeth
The price is £94
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites Southwest/Sioux Falls
An outdoor patio with a round table and wicker chairs, a fire pit, and a brick wall.

18. Fairfield Inn & Suites Sioux Falls Airport

Fairfield Inn & Suites Sioux Falls Airport
3.0 star property
Northwest Sioux Falls, 3.7 mi from Sanford USD Medical Center
9.4 out of 10, Exceptional, (822 reviews)
"Nice place, safe area. Comfortable beds, cool air, clean rooms. Definitely would stay again"
United States
Penny
The price is £91
includes taxes & fees
6 Dec - 7 Dec
Fairfield Inn & Suites Sioux Falls Airport
A La Quinta Inn & Suites building with a covered entrance and multiple windows.

19. La Quinta Inn & Suites by Wyndham Sioux Falls

La Quinta Inn & Suites by Wyndham Sioux Falls
3.0 star property
Mall District, 2.6 mi from Sanford USD Medical Center
9.2 out of 10, Wonderful, (1,538 reviews)
"Very nice place to stay☺️"
United States
Rickey
The price is £78
includes taxes & fees
15 Nov - 16 Nov
La Quinta Inn & Suites by Wyndham Sioux Falls
A Hampton Inn hotel with a modern design, featuring a prominent red sign, a covered entrance, and stone pillars.

20. Hampton Inn Sioux Falls

Hampton Inn Sioux Falls
2.5 star property
Mall District, 2 mi from Sanford USD Medical Center
9.4 out of 10, Exceptional, (1,005 reviews)
"Very friendly staff, good choices at breakfast and comfortable room."
United States
Mary
The price is £90
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn Sioux Falls
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Sanford USD Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious bar area with a large TV screen, a fireplace, and a wine rack.
Highpoint Hotel
3.0 star property
9.6
Exceptional
420 reviews
View
A large, two-story building with a stone facade and multiple windows, illuminated by warm lighting.
Clubhouse Hotel Suites Sioux Falls
3.0 star property
9.6
Exceptional
1,266 reviews
View
A lobby with a large safe, a checkered floor, and a sofa with cushions.
Hotel On Phillips
2.5 star property
9.6
Exceptional
1,642 reviews
View
A patio with wicker chairs and a round table with a fire pit.
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
9.4
Exceptional
682 reviews
View
A modern lobby with a glass fireplace, seating areas, and indoor plants.
Canopy By Hilton Sioux Falls Downtown
4.0 star property
9.4
Exceptional
294 reviews
View

Hotels recommended for families near Sanford USD Medical Center

A spacious bar area with a large TV screen, a fireplace, and a wine rack.

Highpoint Hotel

Highpoint Hotel
3.0 star property
University Heights
9.6 out of 10, Exceptional, (420)
The price is £95
includes taxes & fees
13 Dec - 14 Dec
Highpoint Hotel

Top Sanford USD Medical Center Hotel Reviews

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

10/10 Excellent
"they can use more lighting for their parking lots, due to alot of break in vehicles, no one would be caught as to lighting sucks...... but it was a great hotel.... great service family friendly."
Vanessa 1-night trip
Posted 3 hours ago
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Frequently asked questions

What's the area like around Sanford USD Medical Center?
Sanford USD Medical Center is located in a welcoming area of Sioux Falls known for its beautiful waterfalls and sporting events. If you're looking for a convenient place to stay, take a look at the 138 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Sanford USD Medical Center?
Adjacent to Sanford USD Medical Center, Highpoint Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and free parking. Other good choices close by include Valley Inn and Home2 Suites By Hilton Sioux Falls/Sanford Medical Center.
How many hotels should I expect to find close to Sanford USD Medical Center?
Expedia has 138 hotels and other accommodation options within a mile from Sanford USD Medical Center.
If I need to cancel the hotel reservation for my stay near Sanford USD Medical Center, will I receive a refund?
Yes! Most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to get the best deals near Sanford USD Medical Center.
What can I see and do near Sanford USD Medical Center?
Study the collections at Washington Pavilion of Arts and Science, Old Courthouse Museum or Sioux Empire Medical Museum. Learn about local history at St. Joseph Cathedral and Pettigrew Home and Museum. You can enjoy live performances at Edith Mortenson Theatre Center and Orpheum Theatre Center.