Title: San Sisto Holidays 2026 from £175 | Expedia.co.uk [San Sisto Travel Guide](https://expedia.co.uk/San-Sisto.dx3000377291)[Hotels in San Sisto](https://expedia.co.uk/San-Sisto-Hotels.d3000377291.Travel-Guide-Hotels)[Holiday Rentals in San Sisto](https://expedia.co.uk/San-Sisto-Holiday-Rentals.d3000377291.Travel-Guide-HolidayRentals)[San Sisto Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Sisto.d3000377291.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # San Sisto Holidays from £175 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected #### Your San Sisto Holiday An easy way to experience this interesting city is with a customised San Sisto holiday package. Stay in the neighbourhood of San Biagio della Valle, which is good for views, nature and history or go someplace else — our package deals are all about you. Make your trip to San Sisto even more fun by including some sightseeing. [Piazza IV Novembre](https://www.expedia.co.uk/Piazza-IV-Novembre-Old-Town-Perugia.d6073770.Attraction), [Rocca Paolina](https://www.expedia.co.uk/Rocca-Paolina-Old-Town-Perugia.d6073792.Attraction) and [Basilica San Pietro](https://www.expedia.co.uk/Basilica-San-Pietro-Old-Town-Perugia.d6077838.Attraction) are some of the major attractions worth exploring. Expedia is here to help you escape your daily routine. Tailor your holiday to San Sisto to suit your style of travel, whatever that may be. ## Top San Sisto Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Grand Hotel Elite](https://images.trvl-media.com/lodging/5000000/4330000/4320500/4320466/650ca655_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Grand Hotel Elite £175 per person 8 Jun - 12 Jun found 3 hours ago Return flight included Manchester (MAN) to Perugia San Francesco d'Assisi – Umbria Intl. Airport (PEG) 9/10 Wonderful! (19 reviews) Very beautiful place, large rooms and nice people Reviewed on 19 Sept 2023 ![Sina Brufani](https://images.trvl-media.com/lodging/1000000/30000/27300/27255/d1aec88a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Sina Brufani Old Town Perugia £273 per person 19 Jun - 21 Jun found 4 hours ago Return flight included Manchester (MAN) to Perugia San Francesco d'Assisi – Umbria Intl. Airport (PEG) 9.2/10 Wonderful! (629 reviews) This is a wonderful hotel with friendly, helpful staff. Great location, great breakfast, great rooms. Reviewed on 23 Feb 2026 ![City Hotel & Suites Foligno](https://images.trvl-media.com/lodging/1000000/590000/580800/580794/2b6f2865_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### City Hotel & Suites Foligno £217 per person 8 Jun - 12 Jun found 4 hours ago Return flight included Manchester (MAN) to Perugia San Francesco d'Assisi – Umbria Intl. Airport (PEG) 9.2/10 Wonderful! (413 reviews) The hotel is excellent. The staff are very helpful and welcoming. The a/c was not cool enough for August. The desk clerk arranged a taxi for us to dinner and the taxi returned exactly on time. The breakfast was very good and abundant. Comfortable bed and very nice clean bathroom. The city #1 bus leaves the train station and takes you to Agora bus stop directly in front of the hotel in a few minutes. Buy tickets in the train station bar. The bus does not run at night. The Old Town was further away than we anticipated, and the walk there is longer than expected. Reviewed on 28 Aug 2024 ![International Hotel & Suite](https://images.trvl-media.com/lodging/4000000/3290000/3281400/3281391/355bec8a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### International Hotel & Suite £235 per person 8 Jun - 12 Jun found 4 hours ago Return flight included Manchester (MAN) to Ancona (AOI) 8.6/10 Excellent! (243 reviews) Rooms were tiny. We paid extra for a larger room. I would hate to have seen the smaller one. Staff were excellent. Lots of building work going on so very noisy. Restaurant not open. Very few restaurants nearby were open. Would have been nice to be warned Reviewed on 23 May 2025 ![Grand Hotel Palace](https://images.trvl-media.com/lodging/1000000/50000/45800/45710/b98d449e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Grand Hotel Palace £228 per person 12 May - 15 May found 5 hours ago Return flight included London (LON) to Ancona (AOI) 9.6/10 Exceptional! (356 reviews) Nice hotel, near the port. Enjoyed it for a one night stay. Reviewed on 20 Feb 2026 ## San Sisto Essential Information | Language | Italian | | --------------- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Euros | | Local Welcome | Ciao | | Local Goodbye | Ciao | | Closest Airport | Sant Egidio Airport (PEG) | | Max Temp Winter | 10ºC | | Max Temp Summer | 29ºC | | Top Sights | [Cathedral of Saint Lorenzo](https://www.expedia.co.uk/Cathedral-Of-Saint-Lorenzo-Old-Town-Perugia.d6077846.Attraction), [Citta della Domenica](https://www.expedia.co.uk/Citta-Della-Domenica-Perugia.d553248621532500659.Attraction) and [Castello di Ramazzano](https://www.expedia.co.uk/Castello-Di-Ramazzano-Perugia.d553248621532500519.Attraction) | ## Top hotels in San Sisto ![Villa di Piazzano - Small Luxury Hotel of the World](https://images.trvl-media.com/lodging/1000000/980000/972000/971985/c358cc6c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Villa di Piazzano - Small Luxury Hotel of the World Localita Piazzano, C.P. 6 Cortona AR £581 29 Apr - 30 Apr includes taxes & fees 9.8/10 Exceptional! (228 reviews) Room was wonderful, bathroom spacious and well appointed. Staff amazing and so friendly Reviewed on 6 Nov 2025 [](https://expedia.co.uk/Hotel-Search?startDate=29%2F04%2F2026&endDate=30%2F04%2F2026&selected=971985&PinnedHotelID=971985&HadPinnedHotel=true®ionId=3000377291) ![Hotel Sangallo Palace](https://images.trvl-media.com/lodging/1000000/790000/787200/787189/859da195_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Sangallo Palace Via L Masi 9 Perugia PG Fully refundableReserve now, pay when you stay £131 20 Apr - 21 Apr includes taxes & fees 8.8/10 Excellent! (627 reviews) This is a very nice full service hotel in good location for taking escalators up to the old city. Clean room. Great breakfast. Reviewed on 10 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=20%2F04%2F2026&endDate=21%2F04%2F2026&selected=787189&PinnedHotelID=787189&HadPinnedHotel=true®ionId=3000377291) ![Giotto Hotel & Spa](https://images.trvl-media.com/lodging/3000000/2550000/2544400/2544317/c322aa7a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Giotto Hotel & Spa Via Fontebella 41 Assisi PG Fully refundableReserve now, pay when you stay £107 14 Apr - 15 Apr includes taxes & fees 8.8/10 Excellent! (783 reviews) Lots of shops nearby. And easy access to everything. Our room has a nice view Reviewed on 20 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=14%2F04%2F2026&endDate=15%2F04%2F2026&selected=2544317&PinnedHotelID=2544317&HadPinnedHotel=true®ionId=3000377291) [See all 3,457 properties in San Sisto](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=09%2F04%2F2026&endDate=10%2F04%2F2026®ionId=3000377291) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### Popular places to visit ![Piazza IV Novembre](https://images.trvl-media.com/place/6073770/669c7920-c2b1-448d-9d04-9f55e1a88733.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Piazza IV Novembre Located in the heart of Perugia, this small square is surrounded by some of the town’s most impressive landmarks. [](https://expedia.co.uk/Piazza-IV-Novembre-Old-Town-Perugia.d6073770.Attraction) ![National Gallery of Umbria](https://images.trvl-media.com/place/6077890/4f97d384-2820-43e2-9cc0-3c5012386678.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### National Gallery of Umbria Discover Umbria’s cultural treasures at its most comprehensive art gallery, where centuries-old works of art bring the past to life. [](https://expedia.co.uk/National-Gallery-Of-Umbria-Old-Town-Perugia.d6077890.Attraction) ![Rocca Paolina](https://images.trvl-media.com/place/6073792/c68828bf-3744-4046-a425-1438278e264a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Rocca Paolina Explore a maze of tunnels and alleys, and visit markets, events and exhibitions in the foundations of a 16th-century fortress. [](https://expedia.co.uk/Rocca-Paolina-Old-Town-Perugia.d6073792.Attraction) ### What to do in San Sisto ![Picture 3 for Activity Perugia: San Lorenzo Cathedral Audioguide Tour](https://mediaim.expedia.com/localexpert/48846732/67356f97-7201-4f6b-9b6f-922373854131.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Perugia: San Lorenzo Cathedral Audioguide Tour £3 per adult [](https://expedia.co.uk/things-to-do/perugia-san-lorenzo-cathedral-audioguide-tour.a48846732.activity-details) ![Perugia: Old Town Walking Tour, Piazza IV Novembre](https://mediaim.expedia.com/localexpert/44633641/00be2add-8f9a-4821-bf24-fede78faf06f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Perugia: Old Town Walking Tour, Piazza IV Novembre £26 per adult [](https://expedia.co.uk/things-to-do/perugia-old-town-walking-tour.a44633641.activity-details) ![Assisi Seraphic Beauty Eco Tour](https://mediaim.expedia.com/localexpert/51013393/5c09dea1-ceb0-495f-bd23-64da9c4c08eb.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Assisi Seraphic Beauty Eco Tour £13 per adult [](https://expedia.co.uk/things-to-do/assisi-seraphic-beauty-eco-tour.a51013393.activity-details) [See all activities in San Sisto](https://expedia.co.uk/things-to-do/search?rid=3000377291) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app