San Sisto Holidays from £141
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- Better togetherSave up to £750 when you book a flight and hotel together*
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- Rest easyPackages with flights are ATOL protected
Your San Sisto Holiday
An easy way to experience this interesting city is with a customised San Sisto holiday package. Stay in the neighbourhood of San Biagio della Valle, which is good for views, nature and history or go someplace else — our package deals are all about you. Make your trip to San Sisto even more fun by including some sightseeing. Piazza IV Novembre, Rocca Paolina and Basilica San Pietro are some of the major attractions worth exploring. Expedia is here to help you escape your daily routine. Tailor your holiday to San Sisto to suit your style of travel, whatever that may be.
Top San Sisto Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
Hotel Internazionale
£217
per person
10 Oct - 14 Oct
found 17 hours ago
Return flight included
London (LON) to Ancona (AOI)
8.8/10 Excellent! (83 reviews)
Very nice hotel - busy week and the restaurant was completely full each night. Food pretty good and service find but you can feel its top of peak season.
Reviewed on 21 Aug 2025
Hotel Fortuna
£190
per person
10 Oct - 14 Oct
found 17 hours ago
Return flight included
London (LON) to Ancona (AOI)
8/10 Very good! (304 reviews)
Great location to the train station. The staff was wonderful. However the area is sketchy at night. The hotel is dirty and not a good stay.
Reviewed on 28 Jul 2026
San Sisto Essential Information
Language | Italian |
|---|---|
Currency | Euros |
Local Welcome | Ciao |
Local Goodbye | Ciao |
Closest Airport | Sant Egidio Airport (PEG) |
Max Temp Winter | 10ºC |
Max Temp Summer | 29ºC |
Top Sights | Cathedral of Saint Lorenzo, Citta della Domenica and Castello di Ramazzano |
Top hotels in San Sisto
Villa di Piazzano - Small Luxury Hotel of the World
Localita Piazzano, C.P. 6 Cortona AR
£581
1 Oct - 2 Oct
includes taxes & fees
9.8/10 Exceptional! (247 reviews)
"Such a fantastic property, the most amazing food and great surroundings. Just a thoroughly lovely experience."
Reviewed on 3 Sept 2026
Giotto Hotel & Spa
Via Fontebella 41 Assisi PG
£78
10 Sept - 11 Sept
includes taxes & fees
9/10 Wonderful! (829 reviews)
"Our bathroom especially the tub area was full of mold and the door on the tub didn’t seal properly so every time we showed there was water all over the floor. There was a ceiling leak in two areas in the bathroom. There was mold around the countertop also. They sent a maintenance man who did not ..."
Reviewed on 7 Sept 2026
TH Assisi - Hotel Cenacolo
Viale Patrono d'Italia 70 Assisi PG
£104
10 Sept - 11 Sept
includes taxes & fees
9.2/10 Wonderful! (691 reviews)
"Good place"
Reviewed on 15 Aug 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular San Sisto attractions
Perugina Chocolate Factory
8.6/10 (58 reviews)
Enjoy an outing to Perugina Chocolate Factory during your stay in San Sisto. Discover the area's jazz scene and cathedral.
What to do in San Sisto
Perugia: Old Town Walking Tour, Piazza IV Novembre
£26
per adult
Frequently asked questions
How much does a San Sisto travel package cost?
Tailor make your San Sisto package from only £141. Pick from any combination of flights, hotels and rental cars to pull together the escape of your dreams. Be sure to add on some activities and experiences!
If I'm not able to travel, can I cancel my San Sisto travel package?
Yes, you can. We get that even the best-laid plans can go awry, so we're happy to help if you have to make changes to your San Sisto travel package. You may be able to change or cancel your itinerary for free if you've booked in the last 24 hours. Your hotel, airline or car rental company may impose a fee if your booking was made more than 24 hours ago. Look up our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.
How do I get a cheap travel package to San Sisto?
Browse and book everything in the one place with our San Sisto travel packages. We have deals on flights, hotels and more that'll keep your pocket happy and your adventurous spirit alive. And, with more than 550 air carriers and 1,000,000 properties worldwide to select from, you have countless opportunities to mix and match all you want.
Does Expedia offer Book Now, Pay Later San Sisto holidays?
Your bank balance shouldn't prevent you from going on holiday, so Expedia has worked out a solution to help. Thanks to our partnership with online lender Klarna, it's easier than ever to book a dream getaway without exhausting your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your trip. Consider one of these flexible payment options:
- Pay monthly holidays: Jet off on that dream holiday sooner with Klarna's manageable monthly instalment plans. If making small repayments each month sounds right for you, pick this option at checkout.
- Pay in instalments holidays: If you want to pay off your escape in multiple transactions, holidays paid in instalments might be the right option for your Book Now, Pay Later holiday through Klarna.
- Low deposit holidays: When you want to jump on an amazing deal but don't have the full amount yet, Klarna's low deposit holiday plan will help you lock in your escape.
Where should I stay in San Sisto?
With so much to discover in San Sisto, we suggest you secure a room in a hotel near its attractions. Piazza IV Novembre, Rocca Paolina and Fontana Maggiore are some top ones to put on your itinerary.
What are the top hotels in San Sisto?
If it's your first time in San Sisto, make a reservation at Chocohotel or Sina Brufani. Both hotels have good amenities and are popular options with lots of travellers.
How far in advance should I book my San Sisto holiday?
While prices change frequently, we generally recommend booking your holiday as early as possible. Many international airfares can be compared on Expedia up to a year in advance. If you're booking late, you might still get lucky. Low prices to San Sisto sometimes appear just weeks before departure.
What does an Expedia San Sisto travel package include?
Hotels, flights and a shiny set of wheels for all your fun road trip adventures. Simply mix and match your preferred bundle and get access to great discounts. Once you've made your booking, add on a few tours and experiences and watch your savings pile up. When it comes to crafting your San Sisto break, you're the one in control!
What should I know before booking a San Sisto travel package?
A travel package can be tailored to your budget and is a fantastic way to make your money go further. How much you include is your call. Rental cars, hotels and flights — come up with a combination that suits your style.
Can I choose my airline with a San Sisto Expedia travel package?
You can, and with more than 550 airlines to choose from around the world, you're not short on choice. Take a look at the available options and see which airline suits your needs and budget.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
