Title: San Francisco Travel Guide: Best of San Francisco, Panama City Travel 2026 | Expedia.co.uk [Hotels in San Francisco](https://expedia.co.uk/San-Francisco-Panama-City-Hotels.0-n553248623199112076-0.Travel-Guide-Filter-Hotels)[Flights to Panama City](https://expedia.co.uk/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.co.uk/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[San Francisco Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Francisco.d553248623199112076.Car-Hire-Guide)[San Francisco Holidays](https://expedia.co.uk/San-Francisco.d553248623199112076.Holidays-City-Breaks) # San Francisco Travel Guide ## Panama City ![The Bridge of the Americas in summer, Panama City](https://images.trvl-media.com/place/553248623199112076/b14d4c65-cc25-49b4-aad3-c708d5b994fc.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![San Francisco](https://images.trvl-media.com/place/2897/00acfc2e-f9b8-4097-adcd-b9e8f47bebc2.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![San Francisco](https://images.trvl-media.com/place/2897/df27e517-e0be-4550-bc06-92be5954aac5.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![San Francisco](https://images.trvl-media.com/place/2897/dfeccf0e-b0de-491d-8fdc-2835a33f8a96.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![San Francisco](https://images.trvl-media.com/place/2897/ad002056-eab0-46bc-8398-21350ee7da55.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit San Francisco Things to do Hotels Where to stay [Panama City travel guide](https://expedia.co.uk/Panama-City.dx2897) --- ### Popular places to visit ![Multiplaza Pacific Mall](https://images.trvl-media.com/place/2897/ad002056-eab0-46bc-8398-21350ee7da55.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Multiplaza Pacific Mall 4.5/5(8 reviews) During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area. [](https://expedia.co.uk/Multiplaza-Pacific-Mall-Panama-City.d6158227.Attraction) #### ATLAPA Conventions Center Learn about the events happening in ATLAPA Conventions Center during your trip to Panama City. Stroll along the seaside in this vibrant area or visit its lively bars. [](https://expedia.co.uk/ATLAPA-Conventions-Center-Panama-City.d6286123.Attraction) #### Pacific Center You can browse for the perfect souvenirs at Pacific Center during your visit to Panama City. You can enjoy the restaurants while in the area. [](https://expedia.co.uk/Pacific-Center-San-Francisco.d633625826652135424.Attraction) #### Multicentro Panama 4/5(1 review) During your trip to Panama City, you can find the perfect gifts to bring home at Multicentro Panama. Stroll along the seaside or visit the casinos in this vibrant area. [](https://expedia.co.uk/Multicentro-Panama-Panama-City.d6158230.Attraction) #### Panama Canal Murals 4/5(1 review) You can learn about the history of Panama City with a stop at Panama Canal Murals. Stroll along the seaside in this vibrant area or visit its top-notch restaurants. [](https://expedia.co.uk/Panama-Canal-Murals-Panama-City.d553248621532965255.Attraction) #### Hospital Punta Pacífica If Hospital Punta Pacífica is what brings you to town, hopefully you'll have a chance to explore more of Panama City. [](https://expedia.co.uk/Hospital-Punta-Pacifica-Panama-City.d553248635976653100.Attraction) ### Things to do ![Panama Canal Half Transit Experience](https://mediaim.expedia.com/localexpert/321774/aaedf0da-89a0-4d89-83d3-75c160e0c523.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Panama Canal Partial Transit £112 per adult **86%** of travellers recommend [](https://expedia.co.uk/things-to-do/panama-canal-partial-transit.a321774.activity-details) ![The OG Crawl by The Panama Barcrawl -](https://mediaim.expedia.com/localexpert/2838239/969272dc-90dd-4b87-ad93-e2bb55d5c032.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### The OG Crawl by The Panama Barcrawl - (Panama City, Panama) £49 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/the-og-crawl-by-the-panama-barcrawl-panama-city.a2838239.activity-details) ![Panama City: POIN Swing Experience](https://mediaim.expedia.com/localexpert/48230798/4a92e11f-d198-4ca4-9014-2aa4dbadaa4f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Panama City: POIN Swing Experience £24 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/panama-city-poin-swing-experience.a48230798.activity-details) ![Panama City Visit an Indian town Embera and waterfall with lunch ](https://mediaim.expedia.com/localexpert/47641779/3731f090-a8bd-4aa7-acd1-3526e60e6d25.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Panama City Visit an Indian town Embera and waterfall with lunch £37 per adult **98%** of travellers recommend [](https://expedia.co.uk/things-to-do/panama-city-visit-an-indian-town-embera-and-waterfall-with-lunch.a47641779.activity-details) ![From Panama City: San Blas Island Hopping Day Tour](https://mediaim.expedia.com/localexpert/47693531/d1fbb899-90d5-48cf-849f-3f9982f6a532.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### From Panama City: San Blas Island Hopping Day Tour £109 per adult **98%** of travellers recommend [](https://expedia.co.uk/things-to-do/from-panama-city-san-blas-island-hopping-day-tour.a47693531.activity-details) ![Slingshot Tour Panama ](https://mediaim.expedia.com/localexpert/690667/a7a71fcc-c587-4df6-b28d-f5596cc92f54.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Slingshot Tour Panama £90 per adult **90%** of travellers recommend [](https://expedia.co.uk/things-to-do/slingshot-tour-panama.a690667.activity-details) [See all activities in Panama City](https://expedia.co.uk/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities) --- ## Top hotels in San Francisco ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sheraton Grand Panama Via Israel And 77th Street Panama City Panama £122 8 Apr - 9 Apr includes taxes & fees Stay at this spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ... 8.6/10 Excellent! (1,002 reviews) Not really Reviewed on 26 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=08%2F04%2F2026&endDate=09%2F04%2F2026&selected=1161&PinnedHotelID=1161&HadPinnedHotel=true®ionId=553248623199112076) ![Ramada Plaza by Wyndham Panama Punta Pacifica](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ramada Plaza by Wyndham Panama Punta Pacifica Via Israel y Calle 71, San Francisco Panama City Panama £76 1 Apr - 2 Apr includes taxes & fees Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ... 9.6/10 Exceptional! (1,158 reviews) Friendly and helpful staff, solid location, rooms were a bit small but quite comfortable and the pool was nice! Overall, would recommend. Reviewed on 25 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=01%2F04%2F2026&endDate=02%2F04%2F2026&selected=8216939&PinnedHotelID=8216939&HadPinnedHotel=true®ionId=553248623199112076) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### JW Marriott Panama Calle Punta Colon, Punta Pacifica Panama City Panama £222 5 Apr - 6 Apr includes taxes & fees Stay at this luxury hotel in Panama City. Enjoy free Wi-Fi, 4 outdoor pools and 3 restaurants. Our guests praise the helpful staff in their reviews. Popular ... 9/10 Wonderful! (1,000 reviews) Fantastic pool. Great food, I'd recommend the fish and chips. Best I've ever had. Great bar. Friendly staff. Reviewed on 19 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=4109123&PinnedHotelID=4109123&HadPinnedHotel=true®ionId=553248623199112076) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Courtyard by Marriott Panama Multiplaza Mall Via Israel Multiplaza Pacific Mall Panama City Panama £97 13 Apr - 14 Apr includes taxes & fees Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. ... 9/10 Wonderful! (1,007 reviews) Breakfast was excellent - tasty, healthy with variety Reviewed on 25 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=13%2F04%2F2026&endDate=14%2F04%2F2026&selected=1145666&PinnedHotelID=1145666&HadPinnedHotel=true®ionId=553248623199112076) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Las Americas Golden Tower Panama Av. Balboa con Calle 53 Panama City Panama £130 24 Apr - 25 Apr includes taxes & fees Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the helpful staff in their ... 9/10 Wonderful! (1,005 reviews) Excelente precio -calidad Reviewed on 25 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=24%2F04%2F2026&endDate=25%2F04%2F2026&selected=9675263&PinnedHotelID=9675263&HadPinnedHotel=true®ionId=553248623199112076) ![Aloft Panama](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/75c7ddd0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Aloft Panama Via Israel & Calle 76 Panama City Panama £98 4 Apr - 5 Apr includes taxes & fees Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and a nightclub. Our guests praise the helpful staff in their reviews. Popular ... 8.6/10 Excellent! (1,000 reviews) Everything was amazing. Staff very friendly and food was delicious at their restaurant. Reviewed on 25 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=04%2F04%2F2026&endDate=05%2F04%2F2026&selected=6577427&PinnedHotelID=6577427&HadPinnedHotel=true®ionId=553248623199112076) [See all 1,552 properties in San Francisco](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=28%2F03%2F2026&endDate=29%2F03%2F2026®ionId=553248623199112076) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check San Francisco hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623199112076&startDate=2026-03-27&endDate=2026-03-28)[27 Mar - 28 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623199112076&startDate=2026-03-27&endDate=2026-03-28) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623199112076&startDate=2026-03-28&endDate=2026-03-29)[28 Mar - 29 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623199112076&startDate=2026-03-28&endDate=2026-03-29) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623199112076&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026)[27 Mar - 29 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623199112076&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026) --- ### Other neighbourhoods around San Francisco ![Aerial cityscape skyline of Panama City ](https://images.trvl-media.com/place/3000663487/91568072-3933-42ec-883a-8d61d004b098.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Obarrio Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area. [](https://expedia.co.uk/Panama-City-Obarrio.dx3000663487) ![Panama, Panama City](https://images.trvl-media.com/place/3000663482/75ea33c8-9ded-4810-b9d9-148b475df4c0.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Punta Pacifica Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Pacific Center or Avenida Balboa. [](https://expedia.co.uk/Panama-City-Punta-Pacifica.dx3000663482) ![ sunset sky above Panama City - cityscape panorama view](https://images.trvl-media.com/place/6285983/edf9080c-62d9-428e-9f0b-1c4fbc3905d3.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Punta Paitilla Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town. [](https://expedia.co.uk/Panama-City-Punta-Paitilla.dx6285983) ![Bella Vista](https://images.trvl-media.com/place/2897/62672ebb-ab68-4df6-9850-2c73cf428908.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Bella Vista Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen. [](https://expedia.co.uk/Panama-City-Bella-Vista.dx3000663485) ![Aerial view of the city skyline of Panama City business district](https://images.trvl-media.com/place/553248635976397615/b2492ae9-32cc-4d8a-be68-800dbeb4944e.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Campo Alegre 3.5/5(5 area reviews) If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing. [](https://expedia.co.uk/Panama-City-Campo-Alegre.dx553248635976397615) ![Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.](https://images.trvl-media.com/place/6245970/dcde0ea1-f452-4e6e-a661-261f8d2489db.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Marbella You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera. [](https://expedia.co.uk/Panama-City-Marbella.dx3000663483) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # San Francisco Travel Guide ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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