San Francesco Holidays from £463

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Your San Francesco Holiday

When a fun city getaway is calling, answer it with a holiday package to San Francesco. The neighbourhood of Vecchiano, which is great for bars and pubs, walking and nature, makes a terrific base for your adventures. Like to explore your new surroundings? Cathedral of Pisa, Knights Square and Pisa Baptistry are among the best places to visit during a trip to San Francesco. Don't put off your visit to this city any longer. The ultimate San Francesco holiday is a few quick clicks away with Expedia.

Top San Francesco Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Aurum Uffizi

Aurum Uffizi

Historic Centre of Florence
Save 100% on your flight
£463
per person
26 Oct - 30 Oct
found 1 day ago
Return flight included
London (LCY) to Florence (FLR)
7.6/10 Good! (1,001 reviews)
Aurum Firenze

Aurum Firenze

Historic Centre of Florence
Save 100% on your flight
£482
per person
26 Oct - 30 Oct
found 1 day ago
Return flight included
London (LCY) to Florence (FLR)
7.6/10 Good! (1,003 reviews)
Brilliant location, no more than 15-20 maximum minutes to walk to all the main sites. The staff worked hard and were very friendly and helpful.

Reviewed on 17 Sept 2026

Hotel degli Orafi

Hotel degli Orafi

Historic Centre of Florence
Save 100% on your flight
£711
per person
26 Oct - 30 Oct
found 1 day ago
Return flight included
London (LCY) to Florence (FLR)
9.6/10 Exceptional! (1,002 reviews)
The hotel was right beside the Uffizzi museum and steps from the Ponte Vecchio. The front desk staff were extremely friendly and helpful, providing a map with walking distances to major attractions and recommending less busy sights to see. They will also recommend some excellent local restaurants for you to try authentic Florentine cuisine and make the reservation for you. Rooms were comfortable and clean with little touches like chocolates every night in your room. The included breakfast was amazing with many choices for both European and North American guests. Highly recommend this hotel

Reviewed on 18 Sept 2026

The Moon Boutique Hotel & Spa

The Moon Boutique Hotel & Spa

Historic Centre of Florence
Save 100% on your flight
£722
per person
26 Oct - 30 Oct
found 1 day ago
Return flight included
London (LCY) to Florence (FLR)
9.6/10 Exceptional! (592 reviews)
Excellent staff. Extremely helpful. Booked reservations for us and always happy to help. Hotel is nice and well maintained. Room was spacious for Italy. Shower was only tight squeeze

Reviewed on 18 Sept 2026

Hotel La Scaletta Al Ponte Vecchio

Hotel La Scaletta Al Ponte Vecchio

Historic Centre of Florence
Save 100% on your flight
£624
per person
26 Oct - 30 Oct
found 1 day ago
Return flight included
London (LCY) to Florence (FLR)
9/10 Wonderful! (1,005 reviews)

San Francesco Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Galileo Galilei Airport (PSA)
Max Temp Winter
10ºC
Max Temp Summer
27ºC
Top Sights
Cathedral of Pisa, Calambrone Beach and Palazzo Blu

Top hotels in San Francesco

Hotel Verdi Pisa

Hotel Verdi Pisa

Piazza della Repubblica, 5 Pisa PI
£106
27 Sept - 28 Sept
includes taxes & fees
8.8/10 Excellent! (225 reviews)
"I LOVED the availability of the staff--someone was always there."

Reviewed on 12 Sept 2026

Hotel Verdi Pisa
Hotel Di Stefano

Hotel Di Stefano

Via Sant Apollonia, 35 Pisa PI
Fully refundableReserve now, pay when you stay
£147
11 Oct - 12 Oct
includes taxes & fees
8.8/10 Excellent! (455 reviews)
"Good value for money and close to the tower!"

Reviewed on 14 Sept 2026

Hotel Di Stefano
You & Me

You & Me

Lungarno Mediceo 40 Pisa PI
£68
7 Oct - 8 Oct
includes taxes & fees
8.6/10 Excellent! (436 reviews)
"lovely little b&b on the river ideal for solo travellers had air con fridge & coffee outside the room. About 15 minute walk to the tower & the train station. Take a 20 minute train trip to Lucca for 4 euros each way, you don’t need a whole day in Pisa"

Reviewed on 15 Sept 2026

You & Me
See all 6,475 properties in San Francesco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular San Francesco attractions

National Museum of San Matteo

8.4/10 (18 reviews)
You can study the exhibits at National Museum of San Matteo, a museum with a story of its own, during your holiday in San Francesco. Amble around this culturally rich area's riverfront and enjoy its lively bars.
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Teatro Verdi

8.0/10 (55 reviews)
Get tickets for a show at Teatro Verdi, a theatre with a story to tell in San Francesco. Stroll along the riverfront in this culturally rich area or visit its lively bars.
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Piazza Garibaldi

8.6/10 (10 reviews)
Find out about the history of Pisa when you spend time at Piazza Garibaldi. Stroll along the riverfront or visit the stunning cathedral in this culturally rich area.
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Church of Santa Caterina d'Alessandria

After visiting Church of Santa Caterina d'Alessandria, make a plan to see the other sights and activities in San Francesco. Stroll along the riverfront or visit the stunning cathedral in this culturally rich area.
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Medici Palace

9.0/10 (2 reviews)
Learn about the local history of San Francesco when you spend time at Medici Palace. Visit the stunning cathedral and lively bars in this culturally rich area.
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Cinema Teatro Lux

Enjoy a performance at Cinema Teatro Lux, a popular theatre in San Francesco. Visit the stunning cathedral and lively bars in this culturally rich area.
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Church of San Michele in Borgo

Church of San Michele in Borgo is just one of the places to see in San Francesco, so why not enjoy the other things to explore during your travels? Stroll along the riverfront in this culturally rich area or visit its lively bars.
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St. Francis Church

After visiting St. Francis Church, make a plan to see the other sights and activities in San Francesco. Amble around this culturally rich area's riverfront and enjoy its lively bars.
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What to do in San Francesco

From Livorno: Bus Transfer to the Leaning Tower of Pisa

From Livorno: Bus Transfer to the Leaning Tower of Pisa

£18
per adult
84% of travellers recommend
From Livorno: Bus Transfer to the Leaning Tower of Pisa
From La Spezia: Shore Excursion to Pisa

From La Spezia: Shore Excursion to Pisa

£33
per adult
94% of travellers recommend
From La Spezia: Shore Excursion to Pisa
From Livorno: Shore Excursion to Florence and Pisa

From Livorno: Shore Excursion to Florence and Pisa

£30
per adult
84% of travellers recommend
From Livorno: Shore Excursion to Florence and Pisa
See all activities in San Francesco

Frequently asked questions

Why should I book my San Francesco holiday with Expedia?
Choose Expedia to arrange your next escape with ease, all in one convenient place. Our insider tip for bagging a terrific deal on a San Francesco getaway? Bundle your hotel, flights and/or car hire into a package holiday. Then throw in some exciting tours and activities. Many bookings also come with flexible cancellation policies, so there's no need to worry if you have to switch up your travel itinerary. Round-the-clock help with changing and cancelling your trip is on-hand via our Customer Service Portal link.
When is the best time of year to holiday in San Francesco?
Peak season falls in May, June and September and is an exciting time to visit — if you don't mind rubbing elbows with the crowds. August, November and December are typically quieter times of the year. With average daytime temperatures of 7ºC, January is the coolest month in San Francesco. The warmest month is July, when you can experience average temperatures of 24ºC during the day. Whatever the temperature, you'll discover plenty to keep you occupied here.
What is the top hotel for my holiday in San Francesco?
Grand Hotel Duomo is an ideal base for an unforgettable getaway in San Francesco, offering all the conveniences you need and more.
How do I get a cheap holiday to San Francesco?
Book everything all in one place with our San Francesco holidays. You'll discover deals on hotels, flights, tours and more that'll keep your hip pocket happy and adventurous side satisfied. And, with more than 400 airlines and 321,000 hotels all over the world to pick from, you'll have endless opportunities to mix and match as you please. Learn more about how you can save money on your holiday when you book a flight and hotel together with Expedia.
What should I do on my San Francesco holiday?
Offering major attractions such as Cathedral of Pisa and Pisa Baptistry, a holiday in San Francesco is filled with fun places to visit. Church of Santa Maria della Spina and Knights Square are a couple of other sights worth discovering.
What is the best area to stay in when on holiday in San Francesco?
There's plenty to do in San Francesco, so spend your nights close to its best sights and spend more time sightseeing. National Museum of San Matteo is one place that should be on your itinerary.
Do I need a visa for my San Francesco holiday?
Visa requirements for San Francesco vary based on your nationality and purpose of your visit. Make sure you check official government websites to determine if you need a visa for your holiday. They'll give you the most up-to-date information, including details about application procedures or any supporting documentation that might be necessary. Research your visa requirements well in advance to ensure a smooth travel experience. Also check to see that your passport has at least six months validity from your return date.
What should I wear on my San Francesco holiday?
Do a little research into the types of clothing people in San Francesco wear, and consider browsing style blogs for some fashion inspiration. You'll want to create a versatile travel wardrobe filled with pieces that work for your destination and show off your unique style. Pack with confidence by monitoring the weather forecast in San Francesco. July brings the warmest temperatures, with daily averages of 24ºC, while January days average 7ºC, making it the coolest time of the year.
What does an Expedia San Francesco holiday include?
Expedia has everything you need to arrange your San Francesco getaway, but what goes into your package is your choice. Select from any combination of flights, hotels and hire cars. Looking for some activities to keep you busy? Once you've made your booking, you can add them on too. Whatever your style or budget, there's a package to match your needs. Expedia features all types of properties, with the most popular in San Francesco including apartments and private holiday homes. With Expedia, you'll always enjoy the flexibility and freedom to tailor your holiday any way you want.
Does Expedia offer Book Now, Pay Later San Francesco holidays?
Your bank balance shouldn't stop you from taking a holiday, so Expedia has come up with a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book a dream getaway without using up all your savings. Klarna offers flexible payment options at checkout that take the worry out of budgeting for your escape. Consider one of these flexible payment options:
  • Pay monthly holidays: Klarna offers the ability to pay in multiple transactions that work for all types of budgets, so you can take that well-deserved holiday now.
  • No-deposit holidays: If not paying ahead of time for your getaway makes clicking that "book now" button easier, go for a no-deposit holiday plan with Klarna so that you can Book Now, Pay Later!
Can I choose my airline with a San Francesco Expedia holiday?
Yes — that's the beauty of an Expedia holiday package. You get to choose. We have access to more than 400 airline partners globally, so you have loads of choice when organising your San Francesco getaway.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.