San Antonio Holidays from £490

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Your San Antonio Holiday

From its rich history to its cultural experiences and beyond, there's a whole lot to love about San Antonio. Discover the wonders of this exciting city with a San Antonio holiday package that's tailor-made for you. Metromall Panama is just one of the must-see attractions to add to your sightseeing agenda during a trip to San Antonio. A few clicks is all it takes to craft the ideal San Antonio holiday on Expedia.

Price found within the past 48 hours. Click for updated prices.
Summit Rainforest & Golf Resort

Summit Rainforest & Golf Resort

4 out of 5
Price was £690, price is now £490 per person
£490
per person
20 Oct - 25 Oct
found 13 hours ago
Return flight included
Montego Bay (MBJ) to Panama City (PTY)
8.4/10 Very Good! (1,006 reviews)
An excellent hotel if you want to be away from the busy city and malls. Clean , safe and amazing if you want to connect with nature. If you are coming Panama to shop I would not recommend staying here because it’s not close to the malls and the old city, it is out of the way . 10 mins away from the Panama Canal and hotel offers free shuttle to some places. Breakfast was great and staff was friendly and rooms were great , I would definitely recommend.

Reviewed on 14 Aug 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was £1,410, price is now £874 per person
£874
per person
20 Oct - 25 Oct
found 13 hours ago
Return flight included
Montego Bay (MBJ) to Panama City (PTY)
9/10 Wonderful! (974 reviews)
clean and functional with excellent staff

Reviewed on 23 Aug 2025

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Punta Paitilla
Price was £810, price is now £581 per person
£581
per person
20 Oct - 25 Oct
found 13 hours ago
Return flight included
Montego Bay (MBJ) to Panama City (PTY)
8.4/10 Very Good! (1,033 reviews)
We had a balcony that overlooked the ocean. Air conditioning system that worked great. Food from room service was very good. Negative situation unable to get a hold of the front desk right away off shifts only one person working the front desk and also incoming calls from room. In a emergency you may have a bad outcome.

Reviewed on 25 Aug 2025

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Punta Paitilla
Price was £856, price is now £620 per person
£620
per person
20 Oct - 25 Oct
found 13 hours ago
Return flight included
Montego Bay (MBJ) to Panama City (PTY)
8.8/10 Excellent! (1,003 reviews)
This is my 3rd time staying at the hotel. Its ina good location. Plenty of options to eat at the Union Market. The staff are super nice and nearly all speak english.

Reviewed on 25 Aug 2025

Hotel La Compania, in the Unbound Collection by Hyatt

Hotel La Compania, in the Unbound Collection by Hyatt

4.5 out of 5
Casco Viejo
Price was £1,133, price is now £833 per person
£833
per person
20 Oct - 25 Oct
found 13 hours ago
Return flight included
Montego Bay (MBJ) to Panama City (PTY)
9.8/10 Exceptional! (227 reviews)
This place is perfect. Great rooftop bar.

Reviewed on 22 Aug 2025

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about San Antonio
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Cerro Viento

1 out of top 10 points of interest in this area

Shopping and restaurants are notable features of Cerro Viento. You might consider stopping by Metromall Panama while you're exploring the neighbourhood.

Find hotels in Cerro Viento

Top hotels in San Antonio

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is £89 per night from 26 Aug to 27 Aug
£89
26 Aug - 27 Aug
includes taxes & fees
9/10 Wonderful! (4,193 reviews)
Great stay
"This hotel gave me one of the most luxurious hotel experiences I’ve ever had. It is centrally located with easy access to all your daily social and business needs. The room was brilliantly designed to ensure for the customer luxury feel, comfort, convenience, and ample space. The staff were very ..."

Reviewed on 23 Aug 2025

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
The price is £160 per night from 7 Sept to 8 Sept
£160
7 Sept - 8 Sept
includes taxes & fees
7.2/10 Good! (1,008 reviews)
"The resort was amazing!!"

Reviewed on 24 Aug 2025

Dreams Playa Bonita Panama - All Inclusive
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is £66 per night from 26 Aug to 27 Aug
£66
26 Aug - 27 Aug
includes taxes & fees
9/10 Wonderful! (430 reviews)
"Definitely an amazing hotel !! I will be back !!!"

Reviewed on 23 Aug 2025

Waymore Hotel Spa & Casino
See all 1,507 properties in San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a San Antonio travel package cost?
We make it easy to travel somewhere new, with San Antonio packages starting from as little as £490. You'll have the flexibility to combine your favourite hotels, airlines and car rental. For the ultimate escape, why not add a couple of activities and tours to your itinerary?
If I'm not able to travel, can I cancel my San Antonio travel package?
Yes you can, and we'll help you every step of the way. You may be able to cancel or amend your San Antonio travel package at no cost within 24 hours of booking. However, you may be charged a fee by your airline, hotel or car rental company for older bookings. If life throws you a curveball, browse our Customer Service Portal for further information.
How do I get a cheap travel package to San Antonio?
Just think of all the amazing things you could do in San Antonio with extra cash in your wallet. Watch your savings stack up when you bundle your airfare and hotel bookings into a San Antonio travel package. You have loads of choice when you book with Expedia too. In fact, you can pick from more than 550 airlines and 1,000,000 hotel options throughout the world. Whether you're heading off with the entire family or adventuring alone, planning a trip to San Antonio is better with a package.
Does Expedia offer Book Now, Pay Later San Antonio holidays?
Expedia has partnered with online lender Klarna to make booking your next trip a bit easier on the wallet. Paying in instalments means you can spread the costs of your dream holiday, leaving you with more cash to splash while you're travelling. Klarna has several payment plans to pick from, so you're sure to find something that falls within your budget. Browse these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams come true sooner with Klarna's easy monthly instalment plans. If paying just a small amount each month works for you, pick this option at checkout.
  • Pay in instalments holidays: Into the idea of paying for your holiday in multiple transactions? Then go for this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the total upfront) makes it easier to click that "book now" button, consider a low deposit holiday payment plan with Klarna.

Where should I stay in San Antonio?
There's loads to explore in San Antonio, so stay near its best sights and allow yourself more time sightseeing. Metromall Panama is one spot to put on your must-see list.
What are the top hotels in San Antonio?
Courtyard by Marriott Panama Metromall and Los Panas Hostel are two of the most sought-after properties in San Antonio. Why not look up the rates and amenities at each and then make a decision?
How far in advance should I book my San Antonio holiday?
Travellers are usually able to browse international flights on Expedia within 12 months of the departure date. Booking at the last minute? With a stroke of luck, it's still possible to purchase a cheap ticket just weeks before your journey.
What does an Expedia San Antonio travel package include?
It depends on what type of trip you're planning. San Antonio travel deals can include car rentals, flights and hotels. You can mix and match to find the package that suits your needs. You can also add on activities and experiences after you've booked to pick up even bigger discounts.
What should I know before booking a San Antonio travel package?
When you book your flights, hotels and car rentals together, you'll enjoy incredible discounts. Whether you're organising an island getaway in a villa or would rather stay in a convenient hotel in the city, Expedia will help make it happen.
Can I choose my airline with a San Antonio Expedia travel package?
With a travel package, the choice is in your hands. Whether you'd like to fly to San Antonio in coach or first class, simply select from the available airline options. Expedia has access to over 550 partner airlines all over the world.

Things to do

Panama city and canal tour's unforgettable.

Panama city and canal tour's unforgettable.

£52
per adult
100% of travellers recommend
Panama city and canal tour's unforgettable.
Slingshot Tour Panama

Slingshot Tour Panama

£88
per adult
80% of travellers recommend
Slingshot Tour Panama
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

£110
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
See all activities in San Miguelito

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.