Title: Reserva Natural Punta Patiño Holidays 2026 from £428 | Expedia.co.uk [Reserva Natural Punta Patiño Travel Guide](https://expedia.co.uk/Reserva-Natural-Punta-Patino.dx553248621532964869)[Hotels in Reserva Natural Punta Patiño](https://expedia.co.uk/Reserva-Natural-Punta-Patino-Hotels.d553248621532964869.Travel-Guide-Hotels)[Holiday Rentals in Reserva Natural Punta Patiño](https://expedia.co.uk/Reserva-Natural-Punta-Patino-Holiday-Rentals.d553248621532964869.Travel-Guide-HolidayRentals)[Flights to Reserva Natural Punta Patiño](https://expedia.co.uk/Cheap-Flights-To-Reserva-Natural-Punta-Patino.d553248621532964869.Travel-Guide-Flights)[Reserva Natural Punta Patiño Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Reserva-Natural-Punta-Patino.d553248621532964869.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Reserva Natural Punta Patiño Holidays from £428 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ## Top Reserva Natural Punta Patiño Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista £428 per person 19 Feb - 22 Feb found 16 hours ago Return flight included Nassau (NAS) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) The staff was very courteous Reviewed on 19 Dec 2025 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo Save 100% on your flight £1,282 per person 7 Feb - 13 Feb found 1 day ago Return direct flight included London (LHR) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Beautiful, centrally located hotel in Casco Viejo. Friendly staff, clean rooms and good breakfast Reviewed on 15 Dec 2025 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco £542 per person 19 Feb - 22 Feb found 16 hours ago Return flight included Nassau (NAS) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) Clean room, comfortable, spacious. The breakfast was really good! Reviewed on 18 Dec 2025 ![MARINN PLACE Financial District](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/c11e781a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### MARINN PLACE Financial District Bella Vista £548 per person 19 Feb - 22 Feb found 16 hours ago Return flight included Nassau (NAS) to Panama City (PTY) 9.2/10 Wonderful! (299 reviews) Second stay, very nice Reviewed on 7 Nov 2025 ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Dreams Playa Bonita Panama - All Inclusive £793 per person 19 Feb - 22 Feb found 16 hours ago Return flight included Nassau (NAS) to Panama City (PTY) 7.4/10 Good! (1,002 reviews) Food is limited choices, There are dress codes for the men so make sure you pack close toe shoes and pants or they will not let you eat. Not all restaurants are open every day. Weddings made restaurants busy long waits and they ran out of some food one of the nights so our choices were limited. Activities you can not just do they are planned at certain times and have to do them with a bunch of others. Reviewed on 15 Dec 2025 ## Top hotels in Reserva Natural Punta Patiño ![Hospedaje casa cultural wounaan](https://images.trvl-media.com/lodging/45000000/44970000/44968200/44968162/54c12b87_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hospedaje casa cultural wounaan Panama canal, Puerto lara Darien Santa Fe Darien 7.6/10 Good! (4 reviews) Good but they need better communicatiy We had a great time during our visit. Apart from walking the village there isn’t much to do. We still made the most of our time and made friends with many locals. We did feel a little uncomfortable at the end of our trip as the president was complaining that we had paid in advance and he expected ... Reviewed on 22 Aug 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=02%2F01%2F2026&endDate=03%2F01%2F2026&selected=44968162&PinnedHotelID=44968162&HadPinnedHotel=true®ionId=553248621532964869) [](https://expedia.co.uk/Hotel-Search?startDate=02%2F01%2F2026&endDate=03%2F01%2F2026&selected=44968162&PinnedHotelID=44968162&HadPinnedHotel=true®ionId=553248621532964869) ![All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/0b910251_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama Guna Yala Comarca Guna Yala Comarca £837 15 Jan - 16 Jan 2026 includes taxes & fees [](https://expedia.co.uk/Hotel-Search?startDate=15%2F01%2F2026&endDate=16%2F01%2F2026&selected=120034445&PinnedHotelID=120034445&HadPinnedHotel=true®ionId=553248621532964869) ![San Blas Big Orange Island "Narasgandub Dummad"](https://images.trvl-media.com/lodging/27000000/26600000/26596500/26596401/2f590283_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### San Blas Big Orange Island "Narasgandub Dummad" Guna Yala Guna Yala Comarca [Get rates](https://expedia.co.uk/Hotel-Search?startDate=02%2F01%2F2026&endDate=03%2F01%2F2026&selected=26596401&PinnedHotelID=26596401&HadPinnedHotel=true®ionId=553248621532964869) [](https://expedia.co.uk/Hotel-Search?startDate=02%2F01%2F2026&endDate=03%2F01%2F2026&selected=26596401&PinnedHotelID=26596401&HadPinnedHotel=true®ionId=553248621532964869) [See all 10 properties in Darién Province](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=642836248323325952) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. 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