Title: TOP Adults Only Resorts & Hotels in Pythagorio for 2026 | Expedia.co.uk [Pythagorio Travel Guide](https://expedia.co.uk/Pythagorio.dx6143006)[Hotels in Pythagorio](https://expedia.co.uk/Pythagorio-Hotels.d6143006.Travel-Guide-Hotels)[Holiday Rentals in Pythagorio](https://expedia.co.uk/Pythagorio-Holiday-Rentals.d6143006.Travel-Guide-HolidayRentals)[Pythagorio Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Pythagorio.d6143006.Car-Hire-Guide)[Pythagorio Holidays](https://expedia.co.uk/Pythagorio.d6143006.Holidays-City-Breaks) ![Traditional colorful Greece - travel in beautiful Samos Island, scenic Pythagoion town. view with traditional boats](https://images.trvl-media.com/place/6143006/f8aa132f-5a28-464d-865f-c7c97ddb45c9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6143006/f8aa132f-5a28-464d-865f-c7c97ddb45c9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Pythagorio Adults Only Resorts & Hotels Tonight [24 Mar - 25 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6143006&startDate=2026-03-24&endDate=2026-03-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [25 Mar - 26 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6143006&startDate=2026-03-25&endDate=2026-03-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) This weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6143006&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6143006&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Our top choices for Pythagorio adults-only hotels ![Exterior](https://images.trvl-media.com/lodging/16000000/15470000/15465700/15465639/7ae5ad7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | 1 bedroom, premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/16000000/15470000/15465700/15465639/dab621df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Private kitchenette | Full-sized fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/16000000/15470000/15465700/15465639/5d434515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15470000/15465700/15465639/c49c3e4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nafsika Sea View Apartments [](https://www.expedia.co.uk/Samos-Hotels-Nafsika-Villas.h15465639.Hotel-Information) Samos 9.8/10 Exceptional (22 reviews) "Excellent place for holidays. I will back next year. " ![Ireland](https://a.travel-assets.com/egds/marks/flags/ie.svg) Przemyslaw £113 includes taxes & fees 28 Mar - 29 Mar [](https://www.expedia.co.uk/Samos-Hotels-Nafsika-Villas.h15465639.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-06&endDate=2026-04-07®ionId=6143006&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ## Top Pythagorio Hotel Reviews ![Proteas Blu Resort - Adults Only](https://images.trvl-media.com/lodging/4000000/3580000/3579900/3579852/04fcce4a_y.jpg) ### Proteas Blu Resort - Adults Only 10/10 Excellent "Perfect" [](https://expedia.co.uk/Samos-Hotels-Proteas-Blu-Resort.h3579852.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - [Hotels with Pool in Kokkari ](https://www.expedia.co.uk/Kokkari-Hotels-Hotels-With-Pool.0-0-d6052055-tHotelswithPool.Travel-Guide-Filter-Hotels) - [Yoga Hotels in Kokkari ](https://www.expedia.co.uk/Kokkari-Hotels-Yoga-Hotels.0-0-d6052055-tYogaHotels.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Paleokastro ](https://www.expedia.co.uk/Paleokastro-Hotels-Adults-Only-Resorts.0-0-d3000468678-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - 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