The Best Hotels Closest to Oxbow Nature Center in Byron - 2026 Updated Prices

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Our top choices for Oxbow Nature Center hotels

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

1. Econo Lodge Mayo Clinic Area

11.2 mi from Oxbow Nature Center

Ashley

£57

includes taxes & fees

15 Nov - 16 Nov

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern restaurant with a counter, seating area, and a TV screen.

A modern lounge area with a sofa, chairs, and tables.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

2. Home2 Suites by Hilton Rochester Mayo Clinic Area

10.4 mi from Oxbow Nature Center

howard

£94

includes taxes & fees

6 Nov - 7 Nov

A modern dining area with high tables, chairs, and pendant lighting.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a parking lot in front.

A reception desk with a large digital screen displaying a cityscape and the word "happy."

A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.

3. Hampton Inn & Suites Rochester-North

7.1 mi from Oxbow Nature Center

Mark

£88

includes taxes & fees

6 Nov - 7 Nov

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

4. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

8.9 mi from Oxbow Nature Center

Brien

£104

includes taxes & fees

6 Nov - 7 Nov

A modern indoor patio with a fire feature, seating, and large windows.

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

5. EVEN Hotel Rochester - Mayo Clinic Area by IHG

9.5 mi from Oxbow Nature Center

James

£105

includes taxes & fees

6 Nov - 7 Nov

A spacious lobby with a reception desk, sofas, and a coffee table.

A lobby with a brown sofa, yellow armchairs, a coffee table, and a clock on the wall.

A hotel room with a large bed, a sofa, a TV, and a desk.

A Sleep Inn hotel with a covered entrance, stone pillars, and a clear blue sky.

6. Sleep Inn & Suites West-Near Medical Center

7 mi from Oxbow Nature Center

Jacqueline

£68

includes taxes & fees

15 Nov - 16 Nov

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A hotel room with a sofa, armchairs, a small kitchenette, a flat-screen TV, and a large window.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

A hotel room with a bed, a sofa, a desk, a TV, and a wall art piece.

7. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

9.3 mi from Oxbow Nature Center

MATTHEW

£89

includes taxes & fees

6 Nov - 7 Nov

A Comfort Inn hotel with a stone facade, a covered entrance, and a parking area.

A spacious living room with a stone fireplace, blue sofas, and a flat-screen TV.

A modern dining area with wooden tables and chairs, a kitchen with granite countertops, and a view of the outdoors through large windows.

A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a TV, and a large mirror.

8. Comfort Inn & Suites West - Medical Center

7.1 mi from Oxbow Nature Center

Tammy

£75

includes taxes & fees

15 Nov - 16 Nov

An indoor swimming pool with a dolphin sculpture, wooden ceiling, and clear windows.

A hotel reception area with a red 'Hello' sign, a reception desk, a coffee station, and a fireplace.

A hotel room with a large bed, two bedside tables with lamps, a telephone, and a window with sheer curtains.

A hotel room with a flat-screen TV, a sofa with a red pillow, a small table, and a lamp.

9. TownePlace Suites by Marriott Rochester

7.2 mi from Oxbow Nature Center

Kari

£84

includes taxes & fees

6 Nov - 7 Nov

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

A compact kitchen with a microwave, refrigerator, and coffee maker. A small bar stool is near the counter.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

10. Quality Inn & Suites Mayo Clinic Area

11 mi from Oxbow Nature Center

Jessica

£59

includes taxes & fees

13 Nov - 14 Nov

A modern hotel room with a large window, a sofa set, a dining table, and a lamp.

A rooftop terrace with outdoor seating and a city skyline in the background.

A hotel room with a large bed, a sofa, a desk with a TV, and a view of the city.

A modern indoor swimming pool with clear water, surrounded by lounge chairs and a seating area with a patterned wall.

11. Hilton Rochester Mayo Clinic Area

10.2 mi from Oxbow Nature Center

Jennifer

£153

includes taxes & fees

7 Nov - 8 Nov

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.

A modern kitchen with a built-in microwave, a coffee machine, and a sink.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

12. Staybridge Suites Rochester - Mayo Clinic Area by IHG

9.5 mi from Oxbow Nature Center

Amanda

£100

includes taxes & fees

1 Nov - 2 Nov

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

13. Hampton Inn Rochester-South

11 mi from Oxbow Nature Center

dennis

£77

includes taxes & fees

8 Nov - 9 Nov

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

A modern kitchen with wooden cabinets, a microwave, an oven, and a dishwasher.

A hotel room with two beds, a desk, a chair, and a mirror.

A bar with wooden stools and a neon sign.

14. AmericInn by Wyndham Rochester Near Mayo Clinic

10.9 mi from Oxbow Nature Center

blake

£63

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with a dark countertop, black cabinets, a microwave, and a refrigerator. There are two pendant lights above the counter.

A hotel room with a large round table, two sofas, a TV, and a bed.

A hotel gym with treadmills, elliptical machines, and free weights.

A reception area with a clock, a counter, and a nameplate.

15. Candlewood Suites Rochester Mayo Clinic Area by IHG

11 mi from Oxbow Nature Center

Kevin

£92

includes taxes & fees

15 Nov - 16 Nov

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

A conference room with multiple tables and chairs, ceiling fans, and artwork on the walls.

A modern hotel lobby with a stone wall fireplace, comfortable seating, and a chandelier.

An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.

16. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

9.3 mi from Oxbow Nature Center

Lin

£96

includes taxes & fees

23 Nov - 24 Nov

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

A garden with a water feature, rocks, and yellow umbrellas.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

17. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10.1 mi from Oxbow Nature Center

Deanna

£98

includes taxes & fees

4 Nov - 5 Nov

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a modern building with a brick facade.

A modern interior with a large dining table, sofas, and a kitchen area.

A modern pool table in a spacious, well-lit room with large windows and a bar area.

18. The Berkman

9.3 mi from Oxbow Nature Center

Suzette

£144

includes taxes & fees

24 Oct - 25 Oct

A coffee shop interior with a wooden counter, menu boards, and seating area.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

A hotel room with a bed, bedside table, and a window with curtains.

19. TownePlace Suites by Marriott Rochester Mayo Clinic Area

9.9 mi from Oxbow Nature Center

Cory

£118

includes taxes & fees

6 Nov - 7 Nov

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern bar area with seating and a counter.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

A modern indoor pool area with lounge chairs and a pool.

20. Hyatt House Rochester/Mayo Clinic Area

10 mi from Oxbow Nature Center

Kimberley

£109

includes taxes & fees

30 Oct - 31 Oct

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Compare popular hotels close to Oxbow Nature Center

Property	Property class	Guest rating
Econo Lodge Mayo Clinic Area	9.0 Wonderful 1,008 reviews	View
Home2 Suites by Hilton Rochester Mayo Clinic Area	9.6 Exceptional 1,001 reviews	View
Hampton Inn & Suites Rochester-North	9.2 Wonderful 1,000 reviews	View
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	9.6 Exceptional 748 reviews	View
EVEN Hotel Rochester - Mayo Clinic Area by IHG	9.4 Exceptional 1,000 reviews	View

Top Oxbow Nature Center Hotel Reviews

Sleep Inn & Suites West-Near Medical Center

8/10 Good

"We always stay here on trips to Mayo Clinic. The breakfast is always good. It's a dependable hotel and we've never been disappointed."

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good

"It is an older motel, but it has been updated, For the most part, it was clean. My only complaint is, I know this is a minor thing, but the silverware at breakfast is absolutely worthless. Better, stronger silverware does not cost that much more."

Kahler Inn and Suites - Mayo Clinic Area

8/10 Good

"This hotel was very convenient to Mayo, just a five minute walk. It was especially nice to stay so close to mayo and yet avoid dealing with the construction. Parking was easy to get to if you use the ramp across the street from the hotel. Overall the hotel is a bit dated but very clean. The beds could use replacing as the mattress was saggy. We liked having the extra room of a suite as well as the mini kitchen."

Comfort Inn & Suites West - Medical Center

8/10 Good

"The room was very clean and the beds were comfortable. Breakfast was good with lots of options."

Kahler Grand Hotel

8/10 Good

"Can’t go to a Kahler Grand restaurant and get breakfast. They only have room service for breakfast!"

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"Very nice place, convient, clean"

Extended Stay America Suites Rochester North

10/10 Excellent

"Me gustó que todo está muy limpio y la recepción fueron muy amables . Lo que no me gustó fue el desayuno , lo único que tenía fue café , pan y avena"

Hampton Inn & Suites Rochester-North

10/10 Excellent

"Excelente servició gracias"

TownePlace Suites by Marriott Rochester

10/10 Excellent

"It was a great place! The staff was very helpful!"

Other attractions near Oxbow Nature Center

Zollman Zoo

Visit the native and exotic animals who call Zollman Zoo home during your travels in Byron. Amble around the area's parks or experience its art scene.

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Oxbow Park

8.8/10 (5 reviews)

Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Visit the cosy cafes or top-notch restaurants in this walkable area.

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Kalmar Town Hall

Kalmar Town Hall is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

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Putting Green

Enjoy a round of golf in Byron at Putting Green. Amble around the area's parks or experience its art scene.

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Somerby Golf Club

Enjoy a round of golf in Byron at Somerby Golf Club. Amble around the area's parks or experience its art scene.

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East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Somerby Park

Somerby Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

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Brook Lawn Park

After visiting Brook Lawn Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Frequently asked questions

What's the area like around Oxbow Nature Center?

Oxbow Nature Center is located in Byron. You'll find 7 hotels and other accommodations within a few miles for a convenient home base.

What's the best place to stay close to Oxbow Nature Center?

Kahler Grand Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and an indoor pool. You'll find it 10.1 mi (16.2 km) from Oxbow Nature Center. Other good choices around the area include AmericInn by Wyndham Rochester Near Mayo Clinic and Quality Inn near Medical Center.

How many hotels will I find near Oxbow Nature Center?

Expedia has 7 hotels and other accommodation options a few miles from Oxbow Nature Center.

If I need to cancel the hotel reservation for my stay near Oxbow Nature Center, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available near Oxbow Nature Center.

What can I see and do near Oxbow Nature Center?

If you're looking forward to a day of shopping, consider Byron Town Square, Cheery Meadows Center and High Point Shopping Center and pick out the perfect souvenir. Putting Green, Somerby Golf Club and Links of Byron Mini Golf are worth a stop while you're in the area. Oxbow Park, Zollman Zoo and Kalmar Town Hall are a few additional nearby sights.

Search Hotels Near Oxbow Nature Center, Byron

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Our top choices for Oxbow Nature Center hotels

1. Econo Lodge Mayo Clinic Area

2. Home2 Suites by Hilton Rochester Mayo Clinic Area

3. Hampton Inn & Suites Rochester-North

4. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

5. EVEN Hotel Rochester - Mayo Clinic Area by IHG

6. Sleep Inn & Suites West-Near Medical Center

7. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

8. Comfort Inn & Suites West - Medical Center

9. TownePlace Suites by Marriott Rochester

10. Quality Inn & Suites Mayo Clinic Area

11. Hilton Rochester Mayo Clinic Area

12. Staybridge Suites Rochester - Mayo Clinic Area by IHG

13. Hampton Inn Rochester-South

14. AmericInn by Wyndham Rochester Near Mayo Clinic

15. Candlewood Suites Rochester Mayo Clinic Area by IHG

16. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

17. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

18. The Berkman

19. TownePlace Suites by Marriott Rochester Mayo Clinic Area

20. Hyatt House Rochester/Mayo Clinic Area

Compare popular hotels close to Oxbow Nature Center

Top Oxbow Nature Center Hotel Reviews

Sleep Inn & Suites West-Near Medical Center

AmericInn by Wyndham Rochester Near Mayo Clinic

Kahler Inn and Suites - Mayo Clinic Area

Comfort Inn & Suites West - Medical Center

Kahler Grand Hotel

Hyatt House Rochester/Mayo Clinic Area

Extended Stay America Suites Rochester North

Hampton Inn & Suites Rochester-North

TownePlace Suites by Marriott Rochester

Other attractions near Oxbow Nature Center

Zollman Zoo

Oxbow Park

Kalmar Town Hall

Putting Green

Somerby Golf Club

East Brookfield Park

Somerby Park

Brook Lawn Park

Frequently asked questions