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27 Sept - 28 Sept
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28 Sept - 29 Sept
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2 Oct - 4 Oct
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9 Oct - 11 Oct

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Our top choices for Odessa Regional Medical Center hotels

A modern interior with a high ceiling, exposed beams, and a central staircase. There are seating areas with tables and chairs, and a bar area with a counter.
A modern lobby with a central staircase, seating areas, and a reception desk.
A modern outdoor seating area with a wooden bar, multiple chairs, and potted plants.
A modern interior with a bar area, seating, and a fireplace.

1. Odessa Marriott Hotel & Conference Center

Odessa Marriott Hotel & Conference Center
0.1 mi from Odessa Regional Medical Center
United States
John
£158
includes taxes & fees
2 Oct - 3 Oct
Odessa Marriott Hotel & Conference Center
An outdoor patio area with stone flooring, tables, and chairs.
A hotel room with a large bed, a desk, a chair, a TV, and a window.
A room with two desks, each with a laptop and a chair. There is a bookshelf with colorful books and a door in the background.
A modern hotel lobby with a bar area, seating, and a large screen.

2. Holiday Inn Express & Suites Odessa I-20 by IHG

Holiday Inn Express & Suites Odessa I-20 by IHG
1.9 mi from Odessa Regional Medical Center
United States
Corina I.
£82
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites Odessa I-20 by IHG
A modern kitchen with a central island, bar stools, and a flat-screen TV mounted on the wall.
A MainStay Suites hotel with a modern facade, multiple floors, and a covered entrance.
A gym with cardio machines, a mirror, and a painting on the wall.
A modern lobby with a red sofa, black chairs, a coffee table, and a patterned carpet.

3. MainStay Suites Odessa I-20

MainStay Suites Odessa I-20
1.8 mi from Odessa Regional Medical Center
United States
Alfredo
£65
includes taxes & fees
4 Oct - 5 Oct
MainStay Suites Odessa I-20
A hotel room with a coffee machine, a trash bin, a small table with a potted plant, and a view of a staircase leading to an outdoor area.
A room with a washing machine, a dryer, and a Coca-Cola refrigerator.
A modern hotel lobby with a reception desk, a coffee machine, and a staircase leading to an upper floor.
A hotel room with two beds, a desk with chairs, a flat-screen TV mounted on the wall, and a window with curtains.

4. Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street
1.2 mi from Odessa Regional Medical Center
United States
Susan
£52
includes taxes & fees
29 Sept - 30 Sept
Motel 6 Odessa, TX - 2nd Street
An indoor swimming pool with a clear blue water, surrounded by a tiled deck and a black metal fence.
A reception area with a marble counter, a potted plant, and artwork on the walls.
A restaurant with marble-tiled floors, wooden chairs, and a counter with coffee machines.
A hotel room with two beds, a desk, a chair, a lamp, a TV, and an air conditioning unit.

5. SureStay Plus Hotel by Best Western Odessa

SureStay Plus Hotel by Best Western Odessa
1.6 mi from Odessa Regional Medical Center
United States
Laura
£69
includes taxes & fees
29 Sept - 30 Sept
SureStay Plus Hotel by Best Western Odessa
A hotel room with two beds, a desk, a chair, a heater, and two framed pictures on the walls.
A living room with a sofa, a coffee table, and a vase of flowers.
A corridor with fire extinguishers on the wall, windows, and a covered walkway.
A covered corridor with doors, a parking area, and a clear sky.

6. Villa West Inn

Villa West Inn
1.6 mi from Odessa Regional Medical Center
United States
Armando
£54
includes taxes & fees
29 Sept - 30 Sept
Villa West Inn
A motel with a covered parking area, multiple rooms, and a small commercial space.
A room with a wooden floor, a round table with a vase of flowers, a sofa, and a window with a view of a building outside.
A corridor with a brick wall, a covered walkway, and a view of parked cars.
A compact kitchen with a microwave, coffee maker, and a trash bin. A window offers a view of the outside.

7. Deluxe Inn By Capital O Odessa I-20

Deluxe Inn By Capital O Odessa I-20
1.6 mi from Odessa Regional Medical Center
United States
Alan
£47
includes taxes & fees
29 Oct - 30 Oct
Deluxe Inn By Capital O Odessa I-20
A hotel room with two single beds, each with a patterned bedspread and white pillows. There is a nightstand with a lamp between the beds.
A reception desk with a wooden counter, a computer monitor, and a plant. There are signs for human trafficking and a fire extinguisher.
A compact kitchenette with a microwave, refrigerator, and a small sink. A flat-screen TV is mounted on the wall above a wooden desk with a chair.
A compact hotel room with a washing machine, dryer, and a vending machine.

8. Motel 6 Odessa, TX

Motel 6 Odessa, TX
1.8 mi from Odessa Regional Medical Center
United States
Veronica
£54
includes taxes & fees
29 Sept - 30 Sept
Motel 6 Odessa, TX
A hotel room with a large sliding glass door leading to a balcony, a bed with a blue and white patterned rug, a small table with a potted plant, and a brick wall.
A modern hotel room with a large bed, a desk, a chair, and a view of the outdoors.
A lobby with a large aquarium, red and green seating, and a red carpeted floor.
A hot tub with a brick surround, a swimming pool, lounge chairs, and umbrellas.

9. MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa
3.8 mi from Odessa Regional Medical Center
United States
Jill
£89
includes taxes & fees
4 Oct - 5 Oct
MCM Elegante Hotel and Conference Center Odessa
A covered outdoor seating area with tables and chairs, wooden beams, and a view of the building in the background.
An indoor swimming pool with clear glass walls, surrounded by white chairs and tables, and a wooden ceiling.

10. MCM Grande Hotel FunDome Odessa

MCM Grande Hotel FunDome Odessa
4 mi from Odessa Regional Medical Center
United States
Justin
£63
includes taxes & fees
4 Oct - 5 Oct
MCM Grande Hotel FunDome Odessa
A Courtyard Marriott hotel with a stone facade, multiple windows, and a flagpole.
A hotel lobby with a reception desk, seating area, and artwork on the walls.
An outdoor patio area with a stone fireplace, seating, and a view of the sky.
A hotel lobby with a bar area, seating arrangements, and a large screen displaying information.

11. Courtyard Odessa

Courtyard Odessa
5.3 mi from Odessa Regional Medical Center
United States
alan
£93
includes taxes & fees
18 Oct - 19 Oct
Courtyard Odessa
An outdoor patio with stone flooring, a fire pit, and wicker chairs.
A spacious living area with a fireplace, comfortable seating, and a television mounted on the wall.
A hotel room with a bed, a desk with a chair, a television, and a sofa.
A swimming pool with lounge chairs and a covered seating area.

12. Residence Inn Odessa

Residence Inn Odessa
5.9 mi from Odessa Regional Medical Center
United States
Donna
£84
includes taxes & fees
16 Oct - 17 Oct
Residence Inn Odessa
A spacious living area with a sofa, chairs, and a coffee table. There is a kitchen area with a counter and appliances in the background.
A hotel lobby with multiple seating areas, a coffee station, and a reception desk.
A reception area with a counter, two pendant lights, a decorative wall, and a floor with a patterned rug.
A hotel room with a bed, a sofa, a desk with a chair, a TV, and a lamp.

13. Best Western Plus North Odessa Inn & Suites

Best Western Plus North Odessa Inn & Suites
5.4 mi from Odessa Regional Medical Center
United States
Michael
£76
includes taxes & fees
4 Oct - 5 Oct
Best Western Plus North Odessa Inn & Suites
A hotel pool with lounge chairs and a sign warning against diving.
A hotel lobby with a sofa, two bar stools, a fireplace, a television, and a coffee station.
A modern hotel with a yellow facade, multiple windows, and a covered entrance with flags.
A hotel kitchen with a buffet counter, wooden cabinets, and various kitchen appliances.

14. Homewood Suites by Hilton Odessa

Homewood Suites by Hilton Odessa
5.3 mi from Odessa Regional Medical Center
United States
Melisa
£71
includes taxes & fees
10 Oct - 11 Oct
Homewood Suites by Hilton Odessa
An outdoor seating area with colorful striped sofas and chairs, a central fire feature, and a covered patio with wooden ceiling and glass doors.
A pool area with lounge chairs, a diving board, and a brick wall.
A modern hotel with a covered entrance, a fire lane, and a landscaped area with shrubs.
A hotel room with a sofa, a bedside table with a lamp, a bed, and a wall-mounted telephone.

15. Home2 Suites by Hilton Odessa

Home2 Suites by Hilton Odessa
5.2 mi from Odessa Regional Medical Center
United States
Emilio
£95
includes taxes & fees
4 Oct - 5 Oct
Home2 Suites by Hilton Odessa
An outdoor barbecue area with a grill, seating, and string lights.
A pool area with lounge chairs and a building with multiple windows and a red roof.
A spacious lobby with modern seating, a fireplace, and decorative wall art.
A hotel room with a large bed, a desk, a chair, a sofa, and a TV.

16. TownePlace Suites by Marriott Odessa

TownePlace Suites by Marriott Odessa
3.5 mi from Odessa Regional Medical Center
United States
Issac
£81
includes taxes & fees
17 Oct - 18 Oct
TownePlace Suites by Marriott Odessa
A hotel entrance with a covered walkway, multiple windows, and a brick facade.
A hotel room with a bed, a desk with a computer, a chair, a TV, a coffee maker, and a microwave.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A swimming pool with lounge chairs and a sign indicating no lifeguard on duty.

17. Holiday Inn Odessa by IHG

Holiday Inn Odessa by IHG
4 mi from Odessa Regional Medical Center
United Kingdom
Julian
£73
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Odessa by IHG
An outdoor patio with stone flooring, two wooden benches, a central fire feature, and a gazebo in the background.
A modern kitchen with a central island, wooden cabinetry, and pendant lighting.
A swimming pool with lounge chairs and a poolside bar.
A man working at a desk with a computer, a woman in a red dress seated at a table in the background, and a framed picture on the wall.

18. Staybridge Suites Odessa - Interstate HWY 20 by IHG

Staybridge Suites Odessa - Interstate HWY 20 by IHG
2.8 mi from Odessa Regional Medical Center
United States
Miguel
£86
includes taxes & fees
3 Oct - 4 Oct
Staybridge Suites Odessa - Interstate HWY 20 by IHG
A modern dining area with a long table and chairs, a coffee station, and a large window providing a view of the outdoors.
A modern reception area with a counter, a 'Market' sign, and a refrigerated display case with beverages.
A modern hotel lobby with a reception desk, seating area, and a kitchen in the background.
A modern hotel building with a prominent 'avid' sign, large windows, and a covered outdoor seating area.

19. avid hotel Odessa Northwest by IHG

avid hotel Odessa Northwest by IHG
6.9 mi from Odessa Regional Medical Center
United States
Cecilia
£78
includes taxes & fees
29 Oct - 30 Oct
avid hotel Odessa Northwest by IHG
A reception area with a wooden reception desk, two glass-fronted refrigerators stocked with beverages, and a wall with a decorative light fixture.
A reception desk with a Lenovo monitor, a desktop computer, and a printer. There is a potted plant on the counter and a wall-mounted shelf with decorative items.
A conference room with a round table, green chairs, a potted plant, and a blue carpet.
A swimming pool with lounge chairs and a small building in the background.

20. Fairfield Inn & Suites Odessa

Fairfield Inn & Suites Odessa
3.3 mi from Odessa Regional Medical Center
Canada
Brian
£82
includes taxes & fees
4 Oct - 5 Oct
Fairfield Inn & Suites Odessa
View all properties

Compare popular hotels close to Odessa Regional Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern interior with a high ceiling, exposed beams, and a central staircase. There are seating areas with tables and chairs, and a bar area with a counter.
Odessa Marriott Hotel & Conference Center
9.2
Wonderful
550 reviews
View
An outdoor patio area with stone flooring, tables, and chairs.
Holiday Inn Express & Suites Odessa I-20 by IHG
8.8
Excellent
561 reviews
View
A modern kitchen with a central island, bar stools, and a flat-screen TV mounted on the wall.
MainStay Suites Odessa I-20
8.4
Very good
340 reviews
View
A hotel room with a coffee machine, a trash bin, a small table with a potted plant, and a view of a staircase leading to an outdoor area.
Motel 6 Odessa, TX - 2nd Street
7.8
Good
568 reviews
View
An indoor swimming pool with a clear blue water, surrounded by a tiled deck and a black metal fence.
SureStay Plus Hotel by Best Western Odessa
7.6
Good
103 reviews
View

Top Odessa Regional Medical Center Hotel Reviews

MCM Grande Hotel FunDome Odessa

MCM Grande Hotel FunDome Odessa

10/10 Excellent
"Nice place. I always come here"
Cheryl 1-night trip
Posted less than an hour ago
MCM Grande Hotel FunDome Odessa
MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa

8/10 Good
"This hotel is beautiful. The rooms are great and the staff is fantastic.My only complaint is the road noise that you get if your room is located on the front of the hotel. Sometimes, it sounded as if the cars were in the room with us! And it went on all night long. They really need soundproof windows on the front."
Margie 3-night trip
Posted 4 hours ago
MCM Elegante Hotel and Conference Center Odessa
La Quinta Inn by Wyndham Odessa

La Quinta Inn by Wyndham Odessa

10/10 Excellent
"No issues with checking in. Room was clean, A/c worked great!"
Hayley 1-night trip
Posted 5 hours ago
La Quinta Inn by Wyndham Odessa
Comfort Inn & Suites, Odessa I-20

Comfort Inn & Suites, Odessa I-20

10/10 Excellent
"ok"
Robert 1-night trip
Posted 1 day ago
Comfort Inn & Suites, Odessa I-20
Holiday Inn Express & Suites Odessa I-20 by IHG

Holiday Inn Express & Suites Odessa I-20 by IHG

10/10 Excellent
"Great room at a great price. Best free hotel breakfast ever!"
Arlena 1-night trip
Posted 6 days ago
Holiday Inn Express & Suites Odessa I-20 by IHG
SureStay Plus Hotel by Best Western Odessa

SureStay Plus Hotel by Best Western Odessa

10/10 Excellent
"I was/am very happy with my stay . Management was fabulous and I appreciated thier understanding my needs. This hotel is a oasis. Go to."
Basil 1-night trip
Posted 3 weeks ago
SureStay Plus Hotel by Best Western Odessa
Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street

10/10 Excellent
"This motel was the fastest check in ever. Clean comfortable and quiet. Would totally recommend"
Susan 1-night trip
Posted 1 month ago
Motel 6 Odessa, TX - 2nd Street

Frequently asked questions

What's the area like around Odessa Regional Medical Center?
Odessa Regional Medical Center is located in Odessa. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 9 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Odessa Regional Medical Center?
Adjacent to Odessa Regional Medical Center, Odessa Marriott Hotel & Conference Center is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a few miles include MCM Grande Hotel FunDome Odessa and Motel 6 Odessa, TX - 2nd Street.
How many hotels can I expect to find near Odessa Regional Medical Center?
Expedia has 9 hotels and other accommodation options within a mile from Odessa Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Odessa Regional Medical Center, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best deals near Odessa Regional Medical Center.
What can I see and do near Odessa Regional Medical Center?
Study the collections at White-Pool House, Ellen Noel Art Museum or Presidential Museum and Leadership Library. Create some family memories at Altitude Trampoline Park and Fun City. Attractions like Parker House Museum and Globe of the Great Southwest highlight the local culture.