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Top Hotels Close to Odessa Regional Medical Center

Odessa Marriott Hotel & Conference Center
Outdoor pool, open 10:00 AM to 10:00 PM, pool cabanas (surcharge)

Odessa Marriott Hotel & Conference Center

4.0 star property
9.0 out of 10, Wonderful, (416)
"everything was great, food & drinks we're fantastic "
The price is £137
includes taxes & fees
25 Jul - 26 Jul
Odessa Marriott Hotel & Conference Center
Holiday Inn Express & Suites Odessa I-20 by IHG
Free breakfast

Holiday Inn Express & Suites Odessa I-20 by IHG

2.5 star property
8.8 out of 10, Excellent, (423)
"I loved the friendly staff…how easy it was to check in and out!!! The rooms were spotless and the beds were very comfortable!!"
The price is £68
includes taxes & fees
26 Jul - 27 Jul
Holiday Inn Express & Suites Odessa I-20 by IHG
MainStay Suites Odessa I-20
Desk, laptop workspace, blackout curtains, iron/ironing board

MainStay Suites Odessa I-20

2.5 star property
8.2 out of 10, Very good, (259)
"Was very clean! "
The price is £64
includes taxes & fees
18 Jul - 19 Jul
MainStay Suites Odessa I-20
Motel 6 Odessa, TX - 2nd Street
Lobby

Motel 6 Odessa, TX - 2nd Street

2.0 star property
7.8 out of 10, Good, (479)
"It was nice"
The price is £46
includes taxes & fees
13 Jul - 14 Jul
Motel 6 Odessa, TX - 2nd Street
Villa West Inn
Room, Non Smoking | Rollaway beds, free WiFi

Villa West Inn

2.0 star property
7.6 out of 10, Good, (167)
"Very friendly staff "
The price is £55
includes taxes & fees
13 Jul - 14 Jul
Villa West Inn
SureStay Plus Hotel by Best Western Odessa
Suite, 1 King Bed, Jetted Tub, Pool View (with Sofabed) | View from room

SureStay Plus Hotel by Best Western Odessa

3.0 star property
7.4 out of 10, Good, (62)
"Very nice place to stay "
The price is £76
includes taxes & fees
26 Jul - 27 Jul
SureStay Plus Hotel by Best Western Odessa
DELUX INN
Living area

DELUX INN

2.5 star property
7.2 out of 10, Good, (19)
"Best hotel "
The price is £59
includes taxes & fees
13 Jul - 14 Jul
DELUX INN
Motel 6 Odessa, TX
Blackout curtains, free WiFi, bed sheets

Motel 6 Odessa, TX

2.0 star property
6.8 out of 10, (508)
"Rooms are clean and area is quite "
The price is £53
includes taxes & fees
19 Jul - 20 Jul
Motel 6 Odessa, TX
Staybridge Suites Odessa - Interstate HWY 20 by IHG
Children’s area

Staybridge Suites Odessa - Interstate HWY 20 by IHG

3.0 star property
8.8 out of 10, Excellent, (129)
"Nice and clean property. Friendly staff."
The price is £84
includes taxes & fees
19 Jul - 20 Jul
Staybridge Suites Odessa - Interstate HWY 20 by IHG
TownePlace Suites by Marriott Odessa
Lobby

TownePlace Suites by Marriott Odessa

3.0 star property
9.0 out of 10, Wonderful, (502)
"Great service and breakfast was very good."
The price is £80
includes taxes & fees
18 Jul - 19 Jul
TownePlace Suites by Marriott Odessa
Hawthorn Extended Stay by Wyndham Odessa
Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool loungers

Hawthorn Extended Stay by Wyndham Odessa

3.5 star property
8.6 out of 10, Excellent, (249)
"Will definitely book again!"
The price is £76
includes taxes & fees
19 Jul - 20 Jul
Hawthorn Extended Stay by Wyndham Odessa
Candlewood Suites Odessa by IHG
Property amenity

Candlewood Suites Odessa by IHG

2.5 star property
8.6 out of 10, Excellent, (188)
"Very conveniently located to my ultimate destination. Very friendly and helpful staff. Very quiet and restful."
The price is £81
includes taxes & fees
18 Jul - 19 Jul
Candlewood Suites Odessa by IHG
Fairfield Inn & Suites Odessa
Exterior

Fairfield Inn & Suites Odessa

2.5 star property
8.8 out of 10, Excellent, (392)
"Great staff"
The price is £72
includes taxes & fees
20 Jul - 21 Jul
Fairfield Inn & Suites Odessa
Sleep Inn & Suites Odessa
Desk, laptop workspace, blackout curtains, iron/ironing board

Sleep Inn & Suites Odessa

2.5 star property
8.6 out of 10, Excellent, (454)
"great spot."
The price is £72
includes taxes & fees
19 Jul - 20 Jul
Sleep Inn & Suites Odessa
Hampton Inn by Hilton Odessa
Outdoor pool

Hampton Inn by Hilton Odessa

2.5 star property
8.6 out of 10, Excellent, (341)
"Under renovation as of early July 2025. (1) It needs a renovation, so good for them. (2) Staying at a hotel while its being renovated has some issues naturally."
The price is £72
includes taxes & fees
19 Jul - 20 Jul
Hampton Inn by Hilton Odessa
MCM Elegante Hotel and Conference Center Odessa
View from room

MCM Elegante Hotel and Conference Center Odessa

3.5 star property
8.8 out of 10, Excellent, (1010)
"The Eleganté is a really nicely newly renovated hotel. "
The price is £85
includes taxes & fees
13 Jul - 14 Jul
MCM Elegante Hotel and Conference Center Odessa
Executive Inn Odessa
Property entrance

Executive Inn Odessa

2.5 star property
7.4 out of 10, Good, (162)
"Beds are so comfortable "
The price is £34
includes taxes & fees
13 Jul - 14 Jul
Executive Inn Odessa
Holiday Inn Express Hotel & Suites Odessa by IHG
Breakfast meal

Holiday Inn Express Hotel & Suites Odessa by IHG

2.5 star property
8.8 out of 10, Excellent, (387)
"Great stay"
The price is £76
includes taxes & fees
18 Jul - 19 Jul
Holiday Inn Express Hotel & Suites Odessa by IHG
Studio 6 Odessa, TX
Full-sized fridge, microwave, stovetop, coffee/tea maker

Studio 6 Odessa, TX

2.5 star property
8.0 out of 10, Very good, (213)
"Small kitchen was convenient "
The price is £77
includes taxes & fees
13 Jul - 14 Jul
Studio 6 Odessa, TX
Super 8 by Wyndham Odessa TX
Lobby

Super 8 by Wyndham Odessa TX

2.0 star property
7.8 out of 10, Good, (688)
"Great place "
The price is £58
includes taxes & fees
27 Jul - 28 Jul
Super 8 by Wyndham Odessa TX
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's the area like around Odessa Regional Medical Center?

Odessa Regional Medical Center is located in Odessa. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 11 hotels and other accommodation options you'll find within a mile.

What's the best place to stay close to Odessa Regional Medical Center?

Adjacent to Odessa Regional Medical Center, Odessa Marriott Hotel & Conference Center is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a few miles include MCM Grande Hotel FunDome Odessa and Motel 6 Odessa, TX - 2nd Street.

How many hotels can I expect to find near Odessa Regional Medical Center?

Expedia has 11 hotels and other accommodation options within a mile from Odessa Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Odessa Regional Medical Center, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable if you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best deals near Odessa Regional Medical Center.

What can I see and do near Odessa Regional Medical Center?

Study the collections at White-Pool House, Ellen Noel Art Museum or Parker House Museum. Create some family memories at Altitude Trampoline Park and Fun City. Attractions like Globe of the Great Southwest and Presidential Museum and Leadership Library highlight the local culture.