Default HTG hotel image

Search Hotels Near Odessa Regional Medical Center, Odessa

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
28 Sept - 29 Sept
Tomorrow
29 Sept - 30 Sept
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Filter by

Star rating

Guest rating

Our top choices for Odessa Regional Medical Center hotels

A modern interior with a high ceiling, exposed beams, and a central staircase. There are seating areas with tables and chairs, and a bar area with a counter.
A modern lobby with a central staircase, seating areas, and a reception desk.
A modern outdoor seating area with a wooden bar, multiple chairs, and potted plants.
A modern interior with a bar area, seating, and a fireplace.

1. Odessa Marriott Hotel & Conference Center

Odessa Marriott Hotel & Conference Center
0.1 mi from Odessa Regional Medical Center
United States
John
£158
includes taxes & fees
2 Oct - 3 Oct
Odessa Marriott Hotel & Conference Center
An outdoor patio area with stone flooring, tables, and chairs.
A room with two desks, each with a laptop and a chair. There is a bookshelf with colorful books and a door in the background.
A hotel room with a large bed, a desk, a chair, a TV, and a window.
A modern hotel lobby with seating areas, a bar, and a television screen.

2. Holiday Inn Express & Suites Odessa I-20 by IHG

Holiday Inn Express & Suites Odessa I-20 by IHG
1.9 mi from Odessa Regional Medical Center
United States
Corina I.
£82
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites Odessa I-20 by IHG
A modern kitchen with a central island, bar stools, and a flat-screen TV mounted on the wall.
A gym with cardio machines, a mirror, and a painting on the wall.
A hotel room with two beds, a desk, a chair, and a small table.
A modern lobby with a red sofa, black chairs, a coffee table, and a patterned carpet.

3. MainStay Suites Odessa I-20

MainStay Suites Odessa I-20
1.8 mi from Odessa Regional Medical Center
United States
Alfredo
£65
includes taxes & fees
4 Oct - 5 Oct
MainStay Suites Odessa I-20
A hotel room with a coffee machine, a trash bin, a small table with a potted plant, and a view of a staircase leading to an outdoor area.
A modern hotel room with a kitchenette, a large window with a view of the outside, and a small seating area.
A hotel room with two beds, a desk with chairs, a flat-screen TV mounted on the wall, and a window with curtains.
A room with a washing machine, a dryer, and a Coca-Cola refrigerator.

4. Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street
1.2 mi from Odessa Regional Medical Center
United States
Susan
£52
includes taxes & fees
29 Sept - 30 Sept
Motel 6 Odessa, TX - 2nd Street
An indoor swimming pool with a clear blue water, surrounded by a tiled deck and a black metal fence.
A reception area with a marble counter, a potted plant, and artwork on the walls.
A room with two red sofas, a coffee table, a TV, and large windows.
A restaurant with marble-tiled floors, wooden chairs, and a counter with coffee machines.

5. SureStay Plus Hotel by Best Western Odessa

SureStay Plus Hotel by Best Western Odessa
1.6 mi from Odessa Regional Medical Center
United States
Laura
£69
includes taxes & fees
29 Sept - 30 Sept
SureStay Plus Hotel by Best Western Odessa
A hotel room with two beds, a desk, a chair, a heater, and two framed pictures on the walls.
A corridor with fire extinguishers on the wall, windows, and a covered walkway.
A building facade with a large glass door entrance, a neon 'OPEN' sign, and a yellow curb.
A living room with a sofa, a coffee table, and a vase of flowers.

6. Villa West Inn

Villa West Inn
1.6 mi from Odessa Regional Medical Center
United States
Armando
£54
includes taxes & fees
29 Sept - 30 Sept
Villa West Inn
A motel with a covered parking area, multiple rooms, and a small commercial space.
A compact kitchen with a microwave, coffee maker, and a trash bin. A window offers a view of the outside.
A hotel room with two beds, a desk, a television, and a microwave.
A corridor with a brick wall, a covered walkway, and a view of parked cars.

7. Deluxe Inn By Capital O Odessa I-20

Deluxe Inn By Capital O Odessa I-20
1.6 mi from Odessa Regional Medical Center
United States
Alan
£47
includes taxes & fees
29 Oct - 30 Oct
Deluxe Inn By Capital O Odessa I-20
A hotel room with two single beds, each with a patterned bedspread and white pillows. There is a nightstand with a lamp between the beds.
A compact kitchenette with a microwave, refrigerator, and a small sink. A flat-screen TV is mounted on the wall above a wooden desk with a chair.
A room with a coffee machine, a sign about morning charge, and a poster on the wall.
A compact hotel room with a washing machine, dryer, and a vending machine.

8. Motel 6 Odessa, TX

Motel 6 Odessa, TX
1.8 mi from Odessa Regional Medical Center
United States
Veronica
£54
includes taxes & fees
29 Sept - 30 Sept
Motel 6 Odessa, TX
A hotel room with a large sliding glass door leading to a balcony, a bed with a blue and white patterned rug, a small table with a potted plant, and a brick wall.
A hot tub with a brick surround, a swimming pool, lounge chairs, and umbrellas.
A lobby with a large aquarium, red and green seating, and a red carpeted floor.
A hotel with a prominent 'Eleganté' sign, a parking lot, and a well-maintained lawn.

9. MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa
3.8 mi from Odessa Regional Medical Center
United States
Jill
£89
includes taxes & fees
4 Oct - 5 Oct
MCM Elegante Hotel and Conference Center Odessa
A covered outdoor seating area with tables and chairs, wooden beams, and a view of the building in the background.

10. MCM Grande Hotel FunDome Odessa

MCM Grande Hotel FunDome Odessa
4 mi from Odessa Regional Medical Center
United States
Justin
£63
includes taxes & fees
4 Oct - 5 Oct
MCM Grande Hotel FunDome Odessa
An outdoor barbecue area with a grill, seating, and string lights.
A spacious lobby with modern seating, a fireplace, and decorative wall art.
A spacious lobby with a fireplace, blue seating, a wooden reception desk, and a bookshelf.
A pool area with lounge chairs and a building with multiple windows and a red roof.

11. TownePlace Suites by Marriott Odessa

TownePlace Suites by Marriott Odessa
3.5 mi from Odessa Regional Medical Center
United States
Issac
£81
includes taxes & fees
17 Oct - 18 Oct
TownePlace Suites by Marriott Odessa
A Courtyard Marriott hotel with a stone facade, multiple windows, and a flagpole.
A hotel lobby with a bar area, seating, and a digital screen displaying news.
An outdoor patio area with a stone fireplace, seating, and a view of the sky.
A hotel lobby with a reception desk, seating area, and artwork on the walls.

12. Courtyard Odessa

Courtyard Odessa
5.3 mi from Odessa Regional Medical Center
United States
alan
£93
includes taxes & fees
18 Oct - 19 Oct
Courtyard Odessa
A spacious living area with a sofa, chairs, and a coffee table. There is a kitchen area with a counter and appliances in the background.
A multi-story hotel with a modern design, featuring a prominent 'Best Western PLUS' sign.
A hotel room with a bed, a sofa, a desk with a chair, a TV, and a lamp.
A hotel lobby with multiple seating areas, a coffee station, and a reception desk.

13. Best Western Plus North Odessa Inn & Suites

Best Western Plus North Odessa Inn & Suites
5.4 mi from Odessa Regional Medical Center
United States
Michael
£76
includes taxes & fees
4 Oct - 5 Oct
Best Western Plus North Odessa Inn & Suites
An outdoor patio with stone flooring, a fire pit, and wicker chairs.
A hotel with a covered entrance, multiple flags, and a well-lit facade.
A spacious living area with a fireplace, comfortable seating, and a television mounted on the wall.
A swimming pool with lounge chairs and a covered seating area.

14. Residence Inn Odessa

Residence Inn Odessa
5.9 mi from Odessa Regional Medical Center
United States
Donna
£84
includes taxes & fees
16 Oct - 17 Oct
Residence Inn Odessa
A hotel entrance with a covered walkway, multiple windows, and a brick facade.
A hotel room with a bed, a desk with a computer, a chair, a TV, a coffee maker, and a microwave.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A swimming pool with lounge chairs and a sign indicating no lifeguard on duty.

15. Holiday Inn Odessa by IHG

Holiday Inn Odessa by IHG
4 mi from Odessa Regional Medical Center
United Kingdom
Julian
£73
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Odessa by IHG
A reception area with a wooden reception desk, two glass-fronted refrigerators stocked with beverages, and a wall with a decorative light fixture.
A reception desk with a Lenovo monitor, a desktop computer, and a printer. There is a potted plant on the counter and a wall-mounted shelf with decorative items.
A swimming pool with lounge chairs and a small building in the background.
A Fairfield Inn & Suites Marriott hotel with a covered entrance, multiple floors, and a well-lit facade.

16. Fairfield Inn & Suites Odessa

Fairfield Inn & Suites Odessa
3.3 mi from Odessa Regional Medical Center
Canada
Brian
£82
includes taxes & fees
4 Oct - 5 Oct
Fairfield Inn & Suites Odessa
An outdoor seating area with colorful striped sofas and chairs, a central fire feature, and a covered patio with wooden ceiling and glass doors.
A hotel reception area with a modern design, featuring a reception desk, a digital kiosk, a minibar, and a self-service beverage station.
A hotel room with a sofa, a bedside table with a lamp, a bed, and a wall-mounted telephone.
A modern hotel with a covered entrance, a fire lane, and a landscaped area with shrubs.

17. Home2 Suites by Hilton Odessa

Home2 Suites by Hilton Odessa
5.2 mi from Odessa Regional Medical Center
United States
Emilio
£95
includes taxes & fees
4 Oct - 5 Oct
Home2 Suites by Hilton Odessa
A hotel pool with lounge chairs and a sign warning against diving.
A hotel lobby with a sofa, two bar stools, a fireplace, a television, and a coffee station.
A compact hotel room with a kitchenette, a flat-screen TV, a sofa, and a dining area.
A hotel kitchen with a buffet counter, wooden cabinets, and various kitchen appliances.

18. Homewood Suites by Hilton Odessa

Homewood Suites by Hilton Odessa
5.3 mi from Odessa Regional Medical Center
United States
Melisa
£71
includes taxes & fees
10 Oct - 11 Oct
Homewood Suites by Hilton Odessa
A Holiday Inn Express hotel with a covered entrance, multiple floors, and a stone facade.
A reception area with a wooden reception desk, a blue geometric wall art, and a shelf with snacks.
A bar area with a central island, bar stools, and hanging pendant lights.
A gym with rowing machines, dumbbells, exercise balls, treadmills, and benches.

19. Holiday Inn Express Hotel & Suites Odessa by IHG

Holiday Inn Express Hotel & Suites Odessa by IHG
4.1 mi from Odessa Regional Medical Center
United States
Manuel
£85
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express Hotel & Suites Odessa by IHG
An outdoor patio with stone flooring, two wooden benches, a central fire feature, and a gazebo in the background.
A modern kitchen with dark wooden cabinets, stainless steel appliances, and a central island with seating.
A modern kitchen with a central island, wooden cabinetry, and pendant lighting.
A swimming pool with lounge chairs and a poolside bar.

20. Staybridge Suites Odessa - Interstate HWY 20 by IHG

Staybridge Suites Odessa - Interstate HWY 20 by IHG
2.8 mi from Odessa Regional Medical Center
United States
Miguel
£86
includes taxes & fees
3 Oct - 4 Oct
Staybridge Suites Odessa - Interstate HWY 20 by IHG
View all properties

Compare popular hotels close to Odessa Regional Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern interior with a high ceiling, exposed beams, and a central staircase. There are seating areas with tables and chairs, and a bar area with a counter.
Odessa Marriott Hotel & Conference Center
9.2
Wonderful
550 reviews
View
An outdoor patio area with stone flooring, tables, and chairs.
Holiday Inn Express & Suites Odessa I-20 by IHG
8.8
Excellent
561 reviews
View
A modern kitchen with a central island, bar stools, and a flat-screen TV mounted on the wall.
MainStay Suites Odessa I-20
8.4
Very good
340 reviews
View
A hotel room with a coffee machine, a trash bin, a small table with a potted plant, and a view of a staircase leading to an outdoor area.
Motel 6 Odessa, TX - 2nd Street
7.8
Good
568 reviews
View
An indoor swimming pool with a clear blue water, surrounded by a tiled deck and a black metal fence.
SureStay Plus Hotel by Best Western Odessa
7.6
Good
103 reviews
View

Top Odessa Regional Medical Center Hotel Reviews

La Quinta Inn by Wyndham Odessa

La Quinta Inn by Wyndham Odessa

10/10 Excellent
"Thanks La Quinta"
Marvel 3-night trip
Posted less than an hour ago
La Quinta Inn by Wyndham Odessa
Comfort Inn & Suites, Odessa I-20

Comfort Inn & Suites, Odessa I-20

10/10 Excellent
"ok"
Robert 1-night trip
Posted 2 days ago
Comfort Inn & Suites, Odessa I-20
Holiday Inn Express & Suites Odessa I-20 by IHG

Holiday Inn Express & Suites Odessa I-20 by IHG

10/10 Excellent
"Great room at a great price. Best free hotel breakfast ever!"
Arlena 1-night trip
Posted 6 days ago
Holiday Inn Express & Suites Odessa I-20 by IHG
SureStay Plus Hotel by Best Western Odessa

SureStay Plus Hotel by Best Western Odessa

10/10 Excellent
"I was/am very happy with my stay . Management was fabulous and I appreciated thier understanding my needs. This hotel is a oasis. Go to."
Basil 1-night trip
Posted 3 weeks ago
SureStay Plus Hotel by Best Western Odessa
Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street

10/10 Excellent
"This motel was the fastest check in ever. Clean comfortable and quiet. Would totally recommend"
Susan 1-night trip
Posted 1 month ago
Motel 6 Odessa, TX - 2nd Street

Frequently asked questions

What's the area like around Odessa Regional Medical Center?
Odessa Regional Medical Center is located in Odessa. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 9 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Odessa Regional Medical Center?
Adjacent to Odessa Regional Medical Center, Odessa Marriott Hotel & Conference Center is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a few miles include MCM Grande Hotel FunDome Odessa and Motel 6 Odessa, TX - 2nd Street.
How many hotels can I expect to find near Odessa Regional Medical Center?
Expedia has 9 hotels and other accommodation options within a mile from Odessa Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Odessa Regional Medical Center, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best deals near Odessa Regional Medical Center.
What can I see and do near Odessa Regional Medical Center?
Study the collections at White-Pool House, Ellen Noel Art Museum or Presidential Museum and Leadership Library. Create some family memories at Altitude Trampoline Park and Fun City. Attractions like Parker House Museum and Globe of the Great Southwest highlight the local culture.