Title: O Brien Travel Guide: Best of O Brien, Florida Travel 2026 | Expedia.co.uk [Hotels in O Brien](https://expedia.co.uk/O-Brien-Hotels.d3000431472.Travel-Guide-Hotels)[Holiday Rentals in O Brien](https://expedia.co.uk/O-Brien-Holiday-Rentals.d3000431472.Travel-Guide-HolidayRentals)[O Brien Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-O-Brien.d3000431472.Car-Hire-Guide)[O Brien Holidays](https://expedia.co.uk/O-Brien.d3000431472.Holidays-City-Breaks) # O Brien Travel Guide ## Tourist Guide ![An amazing state Park 2 hours drive from Orlando. Swimming and snorkeling in this crystal clear water is allowed and i really recommend to do it! 🐟🐢](https://images.trvl-media.com/place/6286968/6ef14131-623c-497c-b3f3-edb4a56b8714.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![An amazing state Park 2 hours drive from Orlando. Swimming and snorkeling in this crystal clear water is allowed and i really recommend to do it! 🐟🐢](https://images.trvl-media.com/place/6286968/6ef14131-623c-497c-b3f3-edb4a56b8714.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Suwannee River, Gilchrist County, Florida](https://images.trvl-media.com/place/553248635976197691/0625f9f9-c0ed-4617-a8d6-79a83ac2a33c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Images from the Lower Suwannee River Wildlife Management Area in Florida](https://images.trvl-media.com/place/553248635976197691/5d30ca04-f793-4a65-b5fb-9c2eaed9d3f1.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit O Brien ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=DX_SPRING_PROMO_3000431472) - Top hotels in O Brien - Top Holiday Rentals in O Brien ![Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!](https://images.trvl-media.com/lodging/92000000/91440000/91435900/91435872/c7d330d9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! obrien FL Stay at this beach holiday home in O Brien. Enjoy free Wi-Fi, a beach locale and a fitness centre. Popular attractions Wes Skiles Peacock Springs State Park ... 9.8/10 Exceptional! (33 reviews) Very welcoming and personable hosts. They came over to relatives house and had dinner with us. Very relaxed environment with family and friends. Reviewed on 11 Jan 2026 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=26%2F02%2F2026&endDate=27%2F02%2F2026&selected=91435872&PinnedHotelID=91435872&HadPinnedHotel=true®ionId=3000431472) [](https://expedia.co.uk/Hotel-Search?startDate=26%2F02%2F2026&endDate=27%2F02%2F2026&selected=91435872&PinnedHotelID=91435872&HadPinnedHotel=true®ionId=3000431472) ![Holiday Inn Express & Suites Alachua - Gainesville Area by IHG](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/e851cfaf_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express & Suites Alachua - Gainesville Area by IHG 16367 NW 167TH BLVD Alachua FL £89 22 Feb - 23 Feb includes taxes & fees Stay at this business-friendly hotel in Alachua. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ... 9.4/10 Exceptional! (1,003 reviews) Room was spotless and staff was great. Reviewed on 2 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=22858269&PinnedHotelID=22858269&HadPinnedHotel=true®ionId=3000431472) ![La Quinta Inn & Suite by Wyndham Lake City](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/2886b571_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Quinta Inn & Suite by Wyndham Lake City 165NW CALI DRIVE Lake City FL £85 1 Mar - 2 Mar includes taxes & fees Stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ... 8.6/10 Excellent! (1,070 reviews) Love this hotel. The rooms were clean, the staff was friendly. Will stay there again. Reviewed on 8 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=01%2F03%2F2026&endDate=02%2F03%2F2026&selected=48281488&PinnedHotelID=48281488&HadPinnedHotel=true®ionId=3000431472) [See all 356 properties in O Brien](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=13%2F02%2F2026&endDate=14%2F02%2F2026®ionId=3000431472) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!](https://images.trvl-media.com/lodging/92000000/91440000/91435900/91435872/c7d330d9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! obrien FL Stay at this beach holiday home in O Brien. Enjoy free Wi-Fi, a beach locale and a fitness centre. Popular attractions Wes Skiles Peacock Springs State Park ... 9.8/10 Exceptional! (33 reviews) Very welcoming and personable hosts. They came over to relatives house and had dinner with us. Very relaxed environment with family and friends. Reviewed on 11 Jan 2026 [](https://expedia.co.uk/O-Brien-Hotels-Royal-Springs-Riverfront-Retreat.h91435872.Hotel-Information) ![Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/fce767a1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy 1699 NE Co Rd 337 High Springs FL Stay at this cabin in High Springs. Enjoy free parking, patios and climate control. Popular attractions Ruth B. Kirby Gilchrist Blue Springs State Park and Poe ... 9.8/10 Exceptional! (174 reviews) An amazing experience. They thought of the little things. Boxes of s’mores by the fire. Reviewed on 8 Feb 2026 [](https://expedia.co.uk/High-Springs-Hotels-Postcard-Cabins-Gilchrist-Springs.h110494372.Hotel-Information) ![Peaceful Cabin Getaway • Live Oak, FL](https://images.trvl-media.com/lodging/102000000/101880000/101870900/101870897/66c7d8d5_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Peaceful Cabin Getaway • Live Oak, FL Live Oak FL Stay at this cottage in Live Oak. Enjoy free Wi-Fi, patios and an in-room coffee maker. Popular attractions Suwannee County Historical Museum and First Federal ... 10/10 Exceptional! (25 reviews) Fantastic place, super clean and dreamy! We had an amazing stay Reviewed on 30 Jan 2026 [](https://expedia.co.uk/Live-Oak-Hotels-The-Loft-In-Live-Oak.h101870897.Hotel-Information) [See all properties in O Brien](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=3000431472&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check O Brien hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431472&startDate=2026-02-12&endDate=2026-02-13)[12 Feb - 13 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431472&startDate=2026-02-12&endDate=2026-02-13) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431472&startDate=2026-02-13&endDate=2026-02-14)[13 Feb - 14 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431472&startDate=2026-02-13&endDate=2026-02-14) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431472&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[13 Feb - 15 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431472&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431472&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026)[20 Feb - 22 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000431472&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026) - Cities near O Brien - Places of interest - [Suwannee River State Park ](https://expedia.co.uk/Suwannee-River-State-Park-Florida.d6128386.Attraction) - [North Florida Speedway ](https://expedia.co.uk/North-Florida-Speedway-Lake-City.d6128427.Attraction) - [Epiphany Catholic Church ](https://expedia.co.uk/Epiphany-Catholic-Church-Lake-City.d6285971.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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