Title: TOP Business Hotels in North Central Florida, FL for 2026 | Expedia.co.uk [North Central Florida Travel Guide](https://expedia.co.uk/North-Central-Florida.dx6233773)[Hotels in North Central Florida](https://expedia.co.uk/North-Central-Florida-Hotels.d6233773.Travel-Guide-Hotels)[Holiday Rentals in North Central Florida](https://expedia.co.uk/North-Central-Florida-Holiday-Rentals.d6233773.Travel-Guide-HolidayRentals)[Flights to North Central Florida](https://expedia.co.uk/Cheap-Flights-To-North-Central-Florida.d6233773.Travel-Guide-Flights)[Things to do in North Central Florida](https://expedia.co.uk/Things-To-Do-In-North-Central-Florida.d6233773.Travel-Guide-Activities)[North Central Florida Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-North-Central-Florida.d6233773.Car-Hire-Guide)[North Central Florida Holidays](https://expedia.co.uk/North-Central-Florida.d6233773.Holidays-City-Breaks) ![One of the famous glass bottom boats in Silver Springs State Park (Ocala, FL) floats by on the crystal clear water of the Silver River. If you visit Silver Springs, you must take one of these boat rides. In addition to seeing the underwater springs, we also saw manatees, alligators, turtles, monkeys, and birds on our 90 minute tour. #silversprings #florida](https://images.trvl-media.com/place/10102/70ef890d-5a7e-4d7c-ac71-04c7a28a93cd.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Jen - Nealys On Wheels # Search Business Hotels in North Central Florida - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on North Central Florida Business Hotels Tonight [10 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233773&startDate=2026-01-10&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233773&startDate=2026-01-11&endDate=2026-01-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233773&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233773&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for North Central Florida business-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/13000000/12710000/12704500/12704476/9ec8c850.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/13000000/12710000/12704500/12704476/b0d77cfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/13000000/12710000/12704500/12704476/3c4354df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12710000/12704500/12704476/87e50709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Dunnellon near Rainbow Springs [](https://www.expedia.co.uk/Crystal-River-Hotels-Comfort-Suites-Near-Rainbow-Springs.h12704476.Hotel-Information) Dunnellon 9.0/10 Wonderful (1,000 reviews) "Great location and comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sirbrina £72 includes taxes & fees 21 Jan - 22 Jan [](https://www.expedia.co.uk/Crystal-River-Hotels-Comfort-Suites-Near-Rainbow-Springs.h12704476.Hotel-Information) ![Outdoor pool, open 9:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/w5753h3835x0y5-8b760fc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/45cc4db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/0124d3bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1510000/1505900/1505814/5bb0fbdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Lake City [](https://www.expedia.co.uk/Lake-City-Hotels-Hampton-Inn-Suites-Lake-City.h1505814.Hotel-Information) Lake City 9.4/10 Exceptional (1,002 reviews) "Clean room, staff, everyone super helpful ." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Devang £96 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Lake-City-Hotels-Hampton-Inn-Suites-Lake-City.h1505814.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/2886b571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free on-the-go breakfast on weekdays ](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/9112bbc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/8e94b4a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48290000/48281500/48281488/c38f0eff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suite by Wyndham Lake City [](https://www.expedia.co.uk/Lake-City-Hotels-La-Quinta-Inn-Suite-By-Wyndham-Lake-City.h48281488.Hotel-Information) Lake City 8.8/10 Excellent (1,032 reviews) "Comfortable room and great breakfast / public space. Also, very pet frindly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard £79 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Lake-City-Hotels-La-Quinta-Inn-Suite-By-Wyndham-Lake-City.h48281488.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/430000/429400/429339/fbb41ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/429400/429339/e5855067.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/430000/429400/429339/6e8846d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/430000/429400/429339/c030ccfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Ocala Park Centre [](https://www.expedia.co.uk/Ocala-Hotels-Best-Western-Ocala-Park-Centre.h429339.Hotel-Information) Ocala 8.4/10 Very good (1,224 reviews) "Immaculately Clean room…HELPFUL receptionist… wonderful hot breakfast…comfortable bed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Jeane £59 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Ocala-Hotels-Best-Western-Ocala-Park-Centre.h429339.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/1d4a6615.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/2dd8879c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/847fac5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/35661d50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Alachua I-75 [](https://www.expedia.co.uk/Gainesville-Hotels-Hampton-Inn-Suites-Alachua-I-75.h64474824.Hotel-Information) Alachua 9.4/10 Exceptional (479 reviews) "Good overnight experience on a car trip. Nice staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis £87 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Hampton-Inn-Suites-Alachua-I-75.h64474824.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/800000/798800/798756/ddd17ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/800000/798800/798756/4fd57c66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/798800/798756/09328f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/800000/798800/798756/893e3583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Live Oak by IHG [](https://www.expedia.co.uk/Lake-City-Hotels-Holiday-Inn-Express-Hotel-Suites-LIVE-OAK.h798756.Hotel-Information) Live Oak 8.4/10 Very good (782 reviews) "Property was very clean and no smell of smoke at all soft beds nice tv and desk center walked in shower the pressure could be way batter the the shower and toilet and you have no place to put your trash you have to wait or sit it in the hallway so I advise be mindful of what you eat because the trash might have to sit in your room for a day or so not much to look at on tv so have some movies tittles on hand that you can look for " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Milton £88 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Lake-City-Hotels-Holiday-Inn-Express-Hotel-Suites-LIVE-OAK.h798756.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/8a6fa57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/4e0d3764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/4d594d6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking (Larger Room) | Premium bedding, desk, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/f246ff96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOM Hotel Gainesville, SureStay Collection by Best Western [](https://www.expedia.co.uk/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) Gainesville 8.4/10 Very good (1,808 reviews) "Awesome place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aristeo £64 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1380000/1378800/1378708/0ead3b62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1380000/1378800/1378708/82bfa53d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1380000/1378800/1378708/f498da18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1380000/1378800/1378708/2cdf35a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn White Springs Suwanee [](https://www.expedia.co.uk/Lake-City-Hotels-Quality-Inn.h1378708.Hotel-Information) Live Oak 7.2/10 Good (626 reviews) "Clean rooms, very friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristin L £52 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Lake-City-Hotels-Quality-Inn.h1378708.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/0d00e88d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/efa545ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/33d3a427.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/a3709b54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Gainesville Downtown [](https://www.expedia.co.uk/Gainesville-Hotels-Hyatt-Place-Gainesville-Downtown.h78547624.Hotel-Information) Downtown Gainesville 9.2/10 Wonderful (1,102 reviews) "Loved the location and value " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria £84 includes taxes & fees 13 Jan - 14 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-Hyatt-Place-Gainesville-Downtown.h78547624.Hotel-Information) ![Suite, Multiple Beds, Accessible, Non Smoking | Pillow-top beds, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/2b2698df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/695b0a91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/bb1585dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2480000/2479600/2479520/1d6290c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Lake City [](https://www.expedia.co.uk/Lake-City-Hotels-Comfort-Suites-Lake-City.h2479520.Hotel-Information) Lake City 9.6/10 Exceptional (1,000 reviews) "Clean room, great breakfast and staff super friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary £90 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Lake-City-Hotels-Comfort-Suites-Lake-City.h2479520.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-24&endDate=2026-01-25®ionId=6233773&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top North Central Florida Hotel Reviews ![Comfort Inn University](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/78ca2e85_y.jpg) ### Comfort Inn University 10/10 Excellent "Friendly and informative front desk with complimentary cookie and popcorn!" [](https://expedia.co.uk/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information) ![Sleep Inn & Suites University/Shands](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/3c8617a9_y.jpg) ### Sleep Inn & Suites University/Shands 10/10 Excellent "Everything met our expectations " [](https://expedia.co.uk/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![Equus Inn Ocala](https://images.trvl-media.com/lodging/1000000/30000/27200/27152/8ea1560b_y.jpg) ### Equus Inn Ocala 10/10 Excellent "Clean room, very good breakfast and closer I-75." [](https://expedia.co.uk/Ocala-Hotels-Equus-Inn-Ocala.h27152.Hotel-Information) ![Howard Johnson by Wyndham Ocala FL I-75](https://images.trvl-media.com/lodging/1000000/50000/41500/41471/40bf238e_y.jpg) ### Howard Johnson by Wyndham Ocala FL I-75 10/10 Excellent " good stay for good price hot tub was nice " [](https://expedia.co.uk/Ocala-Hotels-Howard-Johnson-By-Wyndham-Ocala-FL.h41471.Hotel-Information) ![DoubleTree by Hilton Gainesville](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/ff7eaa86_y.jpg) ### DoubleTree by Hilton Gainesville 10/10 Excellent "Amazing staff. 5th time staying here and will continue to stay whenever traveling " [](https://expedia.co.uk/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) ![Hilton University of Florida Conference Center Gainesville](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/7dbdcf15_y.jpg) ### Hilton University of Florida Conference Center Gainesville 10/10 Excellent "Better than expected " [](https://expedia.co.uk/Gainesville-Hotels-Hilton-University-Of-Florida-Conference-Center-Gainesville.h475205.Hotel-Information) ![Days Inn by Wyndham Ocala North](https://images.trvl-media.com/lodging/1000000/10000/900/818/ffb5d22e_y.jpg) ### Days Inn by Wyndham Ocala North 10/10 Excellent "Easy check in clean and nice remodeled room " [](https://expedia.co.uk/Ocala-Hotels-Days-Inn-By-Wyndham-Ocala-North.h818.Hotel-Information) ![Motel 6 Ocala, FL - Conference Center](https://images.trvl-media.com/lodging/1000000/20000/10300/10293/bfb950d1_y.jpg) ### Motel 6 Ocala, FL - Conference Center 8/10 Good "no towels,only 1 for 2 people and not available until morning" [](https://expedia.co.uk/Ocala-Hotels-Motel-6-Ocala.h10293.Hotel-Information) ## Frequently asked questions ### How much do business hotels in North Central Florida cost? ### How many business hotels are there in North Central Florida? ### Why book your business hotel in North Central Florida with Expedia? ### How can I find cheap business hotels in North Central Florida? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Anthony Hotels ](https://www.expedia.co.uk/Anthony-Hotels.d3000420718.Travel-Guide-Hotels) - [Citra Hotels ](https://www.expedia.co.uk/Citra-Hotels.d6317344.Travel-Guide-Hotels) - [Cross Creek Hotels ](https://www.expedia.co.uk/Cross-Creek-Hotels.d553248635975848431.Travel-Guide-Hotels) - 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