Title: TOP Mississippi Delta Spa Hotels for 2026 - Spas in Mississippi Delta, MS | Expedia.co.uk [Mississippi Delta Travel Guide](https://expedia.co.uk/Mississippi-Delta.dx6058692)[Hotels in Mississippi Delta](https://expedia.co.uk/Mississippi-Delta-Hotels.d6058692.Travel-Guide-Hotels)[Holiday Rentals in Mississippi Delta](https://expedia.co.uk/Mississippi-Delta-Holiday-Rentals.d6058692.Travel-Guide-HolidayRentals)[Flights to Mississippi Delta](https://expedia.co.uk/Cheap-Flights-To-Mississippi-Delta.d6058692.Travel-Guide-Flights)[Things to do in Mississippi Delta](https://expedia.co.uk/Things-To-Do-In-Mississippi-Delta.d6058692.Travel-Guide-Activities)[Mississippi Delta Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mississippi-Delta.d6058692.Car-Hire-Guide)[Mississippi Delta Holidays](https://expedia.co.uk/Mississippi-Delta.d6058692.Holidays-City-Breaks) ![Tunica featuring a coastal town and a ferry](https://images.trvl-media.com/place/55209/bfc3ba50-2c50-4588-93f5-11345d258dcc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Tunica Convention and Visitor's Bureau ![](https://images.trvl-media.com/place/55209/bfc3ba50-2c50-4588-93f5-11345d258dcc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mississippi Delta Spa Hotels Tonight [21 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6058692&startDate=2026-03-21&endDate=2026-03-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [22 Mar - 23 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6058692&startDate=2026-03-22&endDate=2026-03-23&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6058692&startDate=2026-03-27&endDate=2026-03-29&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6058692&startDate=2026-04-03&endDate=2026-04-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mississippi Delta hotels with a spa ![Deep-tissue massages, Swedish massages, prenatal massages, Thai massages](https://images.trvl-media.com/lodging/1000000/80000/77900/77838/w5503h3835x0y5-097abf4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, sports bar](https://images.trvl-media.com/lodging/1000000/80000/77900/77838/w5760h3837x0y3-eaab46c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/80000/77900/77838/55e890a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/80000/77900/77838/602ab043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gold Strike Casino Resort [](https://www.expedia.co.uk/Robinsonville-Hotels-Gold-Strike-Casino-Resort.h77838.Hotel-Information) Robinsonville 8.2/10 Very good (1,004 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenneth £96 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Robinsonville-Hotels-Gold-Strike-Casino-Resort.h77838.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/90000000/89200000/89199200/89199107/123f5879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/90000000/89200000/89199200/89199107/04124124.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/90000000/89200000/89199200/89199107/a5a6a8d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89200000/89199200/89199107/fd581289.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at Cedar Grove [](https://www.expedia.co.uk/Vicksburg-Hotels-The-Inn-At-Cedar-Grove.h89199107.Hotel-Information) Vicksburg 9.2/10 Wonderful (163 reviews) "Great historic stay. On-site bar and restaurant. Safe, convenient parking, friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KELLY £107 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Vicksburg-Hotels-The-Inn-At-Cedar-Grove.h89199107.Hotel-Information) ![Body treatments, aromatherapy, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/6524e5a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/bf5689fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 7:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/20dd5b22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/5af47dc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harlow's Casino Resort & Spa [](https://www.expedia.co.uk/Greenville-Hotels-Harlows-Casino-Resort-Spa.h3455562.Hotel-Information) Greenville 7.8/10 Good (1,002 reviews) "relaxing and comfortable rooms after a long drive. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tami £96 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Greenville-Hotels-Harlows-Casino-Resort-Spa.h3455562.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-05&endDate=2026-04-06®ionId=6058692&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Choose what matters most at spa hotels in Mississippi Delta Pool Breakfast included Hot tub 4 stars 5 stars ## Find out more about Mississippi Delta ### Top Mississippi Delta attractions for a relaxing vacation In the heart of the Mississippi Delta, travellers seeking a luxurious spa experience will find the perfect blend of relaxation and cultural richness. Start your journey at the historic town of Clarksdale, known for its vibrant blues music scene; after a day of exploring local juke joints, unwind with a soothing massage at one of the nearby spa hotels. Just a short drive away, the scenic landscapes of the Delta National Forest offer opportunities for tranquil nature walks, where you can immerse yourself in the serene surroundings before retreating to a plush hotel with spa amenities. For a taste of local culture, visit the Delta Blues Museum and then indulge in a rejuvenating facial treatment, inspired by the region's natural ingredients. Don't miss the chance to savour the flavours of Southern cuisine; many hotels offer gourmet dining experiences that complement your spa retreat. The area around Greenville is particularly inviting, with several high-end hotels featuring full-service spas, where attentive staff ensure every need is catered to, providing a pampered experience that aligns with your high expectations. ## Top Mississippi Delta Hotel Reviews ![Hollywood Casino Tunica](https://images.trvl-media.com/lodging/1000000/50000/42400/42301/06298d26_y.jpg) ### Hollywood Casino Tunica 8/10 Good "Clean rooms " [](https://expedia.co.uk/Robinsonville-Hotels-Hollywood-Casino-Tunica.h42301.Hotel-Information) ![Harlow's Casino Resort & Spa](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/20dd5b22_y.jpg) ### Harlow's Casino Resort & Spa 6/10 Okay "Room was nice " [](https://expedia.co.uk/Greenville-Hotels-Harlows-Casino-Resort-Spa.h3455562.Hotel-Information) ![Drury Inn & Suites Memphis Southaven](https://images.trvl-media.com/lodging/1000000/670000/662100/662004/6d8bd337_y.jpg) ### Drury Inn & Suites Memphis Southaven 10/10 Excellent "Excellent stay. Would not hesitate to stay here again. " [](https://expedia.co.uk/Memphis-Hotels-Drury-Inn-Suites-Memphis-Southaven.h662004.Hotel-Information) ![Fitz Tunica Casino & Hotel, Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509765/w419h278x1y1-d0434fb3_y.jpg) ### Fitz Tunica Casino & Hotel, Trademark Collection by Wyndham 2/10 Terrible "Weed! Everywhere weed! The casino was dirty. Machines dirty. When I went to my room, it was reeking with weed. Bathroom floors were dirty. Pillows were awful. Left theroom. Came back later- weed! Called downstairs about the weed. They came and sprayed my room. But allllll night, I smelled weed. Woke up with a headache. Couldn’t sleep for the weed. The pictures on the web looked good. WAS NOT GOOD! Do not stay here unless you like filth. " [](https://expedia.co.uk/Robinsonville-Hotels-Fitz-Casino-Hotel-Tunica.h1509765.Hotel-Information) ![Gold Strike Casino Resort](https://images.trvl-media.com/lodging/1000000/80000/77900/77838/602ab043_y.jpg) ### Gold Strike Casino Resort 8/10 Good "The selections throughout the hotel were great. Even though hot food is available, it would be great to have a microwave to warm leftovers. The friendliness of the staff made my stay quite welcoming. I also enjoyed the on-site gym." 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