Title: TOP Mississippi Delta Spa Hotels for 2025 - Spas in Mississippi Delta, MS | Expedia.co.uk [Mississippi Delta Travel Guide](https://expedia.co.uk/Mississippi-Delta.dx6058692)[Hotels in Mississippi Delta](https://expedia.co.uk/Mississippi-Delta-Hotels.d6058692.Travel-Guide-Hotels)[Holiday Rentals in Mississippi Delta](https://expedia.co.uk/Mississippi-Delta-Holiday-Rentals.d6058692.Travel-Guide-HolidayRentals)[Flights to Mississippi Delta](https://expedia.co.uk/Cheap-Flights-To-Mississippi-Delta.d6058692.Travel-Guide-Flights)[Things to do in Mississippi Delta](https://expedia.co.uk/Things-To-Do-In-Mississippi-Delta.d6058692.Travel-Guide-Activities)[Mississippi Delta Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mississippi-Delta.d6058692.Car-Hire-Guide)[Mississippi Delta Holidays](https://expedia.co.uk/Mississippi-Delta.d6058692.Holidays-City-Breaks) ![Tunica featuring a coastal town and a ferry](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/35000/35087-Tunica.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Mississippi Delta, MS ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mississippi Delta Spa Hotels Tonight [17 Sept - 18 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058692&startDate=2025-09-17&endDate=2025-09-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [18 Sept - 19 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058692&startDate=2025-09-18&endDate=2025-09-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058692&startDate=2025-09-19&endDate=2025-09-21&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058692&startDate=2025-09-26&endDate=2025-09-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mississippi Delta Spa Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20445/w3837h2560x3y3-4647240b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Balcony, Pool View (Four Poster Bed) | 1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/30000/20500/20445/85654b42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20500/20445/w3837h2560x3y3-32afac94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/30000/20500/20445/w3837h2563x3y0-08d8d004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Plus Hotel by Best Western Greenwood Greenwood 8.2/10 Very good (661) "The staffs were very professional and friendly. I truly enjoyed my stay." £106 includes taxes & fees 25 Sept - 26 Sept [](https://www.expedia.co.uk/Grenada-Hotels-SureStay-Plus-Hotel-By-Best-Western-Greenwood.h20445.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/36000000/35040000/35030700/35030665/bdc5610b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/36000000/35040000/35030700/35030665/05883c1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/36000000/35040000/35030700/35030665/b7d5eec3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/36000000/35040000/35030700/35030665/5f8be024.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cotton House, Cleveland, a Tribute Portfolio Hotel Cleveland 9.0/10 Wonderful (589) "Awesome hotel" £125 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Greenville-Hotels-Cotton-House.h35030665.Hotel-Information) ![Body treatments, aromatherapy, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/6524e5a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/e609eec1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 7:00 PM, pool loungers](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/20dd5b22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Egyptian cotton sheets, premium bedding, down duvets, desk](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/5c8ca0d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harlow's Casino Resort & Spa Greenville 7.8/10 Good (1002) "Great stay" £135 includes taxes & fees 10 Oct - 11 Oct [](https://www.expedia.co.uk/Greenville-Hotels-Harlows-Casino-Resort-Spa.h3455562.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/2000000/1190000/1184100/1184076/4145f3a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1190000/1184100/1184076/6ac9f2a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | Iron/ironing board, free cots/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1190000/1184100/1184076/fa3d767b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1190000/1184100/1184076/01cdc9af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Greenwood Greenwood 8.2/10 Very good (494) "The breakfast was great." £122 includes taxes & fees 1 Oct - 2 Oct [](https://www.expedia.co.uk/Grenada-Hotels-Hampton-Inn-Greenwood.h1184076.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/42400/42301/06298d26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/50000/42400/42301/9b4b6540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/50000/42400/42301/acb01c58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/42400/42301/38c3f9a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hollywood Casino Tunica Robinsonville 8.0/10 Very good (1012) "Nice place to stay." £58 includes taxes & fees 18 Sept - 19 Sept [](https://www.expedia.co.uk/Robinsonville-Hotels-Hollywood-Casino-Tunica.h42301.Hotel-Information) ![Deep-tissue massages, Swedish massages, prenatal massages, Thai massages](https://images.trvl-media.com/lodging/1000000/80000/77900/77838/dfc241b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Non Smoking | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/80000/77900/77838/53b374c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/80000/77900/77838/0a8b46cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/80000/77900/77838/602ab043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gold Strike Casino Resort Robinsonville 8.2/10 Very good (1014) "I enjoyed my stay! Will definitely visit again. " £93 includes taxes & fees 18 Sept - 19 Sept [](https://www.expedia.co.uk/Robinsonville-Hotels-Gold-Strike-Casino-Resort.h77838.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/38000000/37290000/37282200/37282158/90499bd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/38000000/37290000/37282200/37282158/340eafc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37290000/37282200/37282158/90b65a8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/38000000/37290000/37282200/37282158/6fc34744.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Greenville Greenville 8.0/10 Very good (500) "Beds comfortable. " £108 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Greenville-Hotels-Tru-By-Hilton-Greenville.h37282158.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/40000/34400/34352/474413e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/40000/34400/34352/d3afcb2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/40000/34400/34352/56fd39a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually furnished, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/40000/34400/34352/c24e0dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Tunica Resort Robinsonville 4.4/10 (31) "It was dirty as hell" [](https://www.expedia.co.uk/Robinsonville-Hotels-Americas-Best-Value-Inn-Tunica-Resort.h34352.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/4000000/3770000/3762500/3762451/4f3cced9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/4000000/3770000/3762500/3762451/02de240c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/4000000/3770000/3762500/3762451/aceb74df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3770000/3762500/3762451/ceb07255.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Yazoo City Yazoo City 8.4/10 Very good (487) "My stay was great, I will be back!" £108 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Yazoo-City-Hotels-Hampton-Inn-Yazoo-City.h3762451.Hotel-Information) ![Desk, blackout curtains, bed sheets](https://images.trvl-media.com/lodging/10000000/9790000/9780700/9780613/50ed5c63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9780700/9780613/6712ff59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9780700/9780613/f93ae836.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9780700/9780613/7272a4e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isle of Capri Casino Hotel Lula – A Caesars Rewards Destination Lula 6.4/10 (1003) "Wonderful experience " £64 includes taxes & fees 23 Sept - 24 Sept [](https://www.expedia.co.uk/Lula-Hotels-Isle-Of-Capri-Casino-Hotel.h9780613.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-01&endDate=2025-10-02®ionId=6058692&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Spa hotels with pools in Mississippi Delta ![Lobby](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/e609eec1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 7:00 PM, pool loungers](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/20dd5b22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/3daa3f5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/f22d92ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harlow's Casino Resort & Spa Greenville 7.8/10 Good (1002) £135 includes taxes & fees 10 Oct - 11 Oct [](https://www.expedia.co.uk/Greenville-Hotels-Harlows-Casino-Resort-Spa.h3455562.Hotel-Information) [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-01&endDate=2025-10-02®ionId=6058692&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&amenities=POOL&openPlayBack=true) ## Spa hotels with gyms in Mississippi Delta ![Lobby](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/e609eec1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 7:00 PM, pool loungers](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/20dd5b22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/3daa3f5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/4000000/3460000/3455600/3455562/f22d92ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harlow's Casino Resort & Spa Greenville 7.8/10 Good (1002) £135 includes taxes & fees 10 Oct - 11 Oct [](https://www.expedia.co.uk/Greenville-Hotels-Harlows-Casino-Resort-Spa.h3455562.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-01&endDate=2025-10-02®ionId=6058692&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&amenities=GYM&openPlayBack=true) ## Find out more about Mississippi Delta ### Top Mississippi Delta attractions for a relaxing vacation In the heart of the Mississippi Delta, travellers seeking a luxurious spa experience will find the perfect blend of relaxation and cultural richness. Start your journey at the historic town of Clarksdale, known for its vibrant blues music scene; after a day of exploring local juke joints, unwind with a soothing massage at one of the nearby spa hotels. Just a short drive away, the scenic landscapes of the Delta National Forest offer opportunities for tranquil nature walks, where you can immerse yourself in the serene surroundings before retreating to a plush hotel with spa amenities. For a taste of local culture, visit the Delta Blues Museum and then indulge in a rejuvenating facial treatment, inspired by the region's natural ingredients. Don't miss the chance to savour the flavours of Southern cuisine; many hotels offer gourmet dining experiences that complement your spa retreat. The area around Greenville is particularly inviting, with several high-end hotels featuring full-service spas, where attentive staff ensure every need is catered to, providing a pampered experience that aligns with your high expectations. ## Top Mississippi Delta Hotel Reviews ![The Guest House at Graceland](//images.trvl-media.com/lodging/15000000/14880000/14873700/14873603/3626d3a4_y.jpg) ### The Guest House at Graceland 10/10 Excellent "The only negative about the Guesthouse is that it's too far from everything. Have to take an Uber/Lyft for some excitement elsewhere. Of course there's Graceland, but seen that already, nothing new about it." [](https://expedia.co.uk/Memphis-Hotels-The-Guest-House-At-Graceland.h14873603.Hotel-Information) ![Fitz Tunica Casino & Hotel, Trademark Collection by Wyndham](//images.trvl-media.com/lodging/2000000/1510000/1509800/1509765/febb6531_y.jpg) ### Fitz Tunica Casino & Hotel, Trademark Collection by Wyndham 10/10 Excellent "Rooms were quiet." [](https://expedia.co.uk/Robinsonville-Hotels-Fitz-Casino-Hotel-Tunica.h1509765.Hotel-Information) ![Hollywood Casino Tunica](//images.trvl-media.com/lodging/1000000/50000/42400/42301/06298d26_y.jpg) ### Hollywood Casino Tunica 10/10 Excellent "Friendly staff, clean and fun!! We will. Definitely be back! " [](https://expedia.co.uk/Robinsonville-Hotels-Hollywood-Casino-Tunica.h42301.Hotel-Information) ![Gold Strike Casino Resort](//images.trvl-media.com/lodging/1000000/80000/77900/77838/602ab043_y.jpg) ### Gold Strike Casino Resort 10/10 Excellent "Very nice" [](https://expedia.co.uk/Robinsonville-Hotels-Gold-Strike-Casino-Resort.h77838.Hotel-Information) ![Ameristar Casino Hotel Vicksburg](//images.trvl-media.com/lodging/3000000/2520000/2516400/2516319/46e018b6_y.jpg) ### Ameristar Casino Hotel Vicksburg 10/10 Excellent "There was no disappointments at this hotel. Good shower pressure, thick towels, generous bottles of shampoo, conditioner and body wash. All my resturant meals were very good. Great chili." [](https://expedia.co.uk/Vicksburg-Hotels-Ameristar-Casino-Hotel-Vicksburg.h2516319.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Anguilla Hotels](https://www.expedia.co.uk/Anguilla-Hotels.d553248635125972568.Travel-Guide-Hotels) - [Belzoni Hotels](https://www.expedia.co.uk/Belzoni-Hotels.d3000444033.Travel-Guide-Hotels) - [Choctaw Hotels](https://www.expedia.co.uk/Choctaw-Hotels.d6060582.Travel-Guide-Hotels) - [Cheap Hotels in Clarksdale](https://www.expedia.co.uk/Clarksdale-Hotels-Budget-Hotels.0-0-d6640-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Clarksdale](https://www.expedia.co.uk/Clarksdale-Hotels-Gay-Friendly-Hotel.0-0-d6640-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Clarksdale Hotels](https://www.expedia.co.uk/Clarksdale-Hotels.d6640.Travel-Guide-Hotels) - [Pet-Friendly Hotels in Cleveland](https://www.expedia.co.uk/Cleveland-Hotels-Pet-Friendly-Hotel.0-0-d7485-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - 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