Title: Mississippi Spa Hotels, United States of America: Mississippi Hotel Guide | Expedia.co.uk [Mississippi Travel Guide](https://expedia.co.uk/Mississippi.dx226)[Mississippi Hotels](https://expedia.co.uk/Destinations-In-Mississippi.d226.Hotel-Destinations)[Holiday Rentals in Mississippi](https://expedia.co.uk/Destinations-In-Mississippi.d226.Holiday-Rental-Destinations)[Mississippi Flights](https://expedia.co.uk/Destinations-In-Mississippi.d226.Flight-Destinations)[Mississippi Car Hire](https://expedia.co.uk/Destinations-In-Mississippi.d226.Car-Hire-Destinations)[Mississippi Holidays](https://expedia.co.uk/Mississippi.d226.Holidays-City-Breaks) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/483000/483399-biloxi.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Spa Hotels in Mississippi - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mississippi Spa Hotels Tonight [4 Nov - 5 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=226&startDate=2025-11-04&endDate=2025-11-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [5 Nov - 6 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=226&startDate=2025-11-05&endDate=2025-11-06&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=226&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=226&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mississippi Spa Hotels ![Reception](https://images.trvl-media.com/lodging/19000000/18420000/18411100/18411003/7c3027e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18420000/18411100/18411003/f28c478e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/19000000/18420000/18411100/18411003/54467fc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18420000/18411100/18411003/6cab3dab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Jackson Downtown Jackson 9.2/10 Wonderful (808) "Great hotel. Enjoyed my stay. Staff very friendly and great room in a good location. Used valet parking which was efficient and reasonable. Easy to walk to various sites." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) George £137 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Jackson-Hotels-The-Westin-Jackson.h18411003.Hotel-Information) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/e7ff60a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/364a95a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 7:30 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/b66654c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 bars/lounges, sports bar](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/fb7837f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beau Rivage Downtown Biloxi 9.2/10 Wonderful (1412) "Nice Hotel! Staff very friendly!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra £128 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Biloxi-Hotels-Beau-Rivage.h199634.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/8419c524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/ceef32e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/5cecdcbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/b0ef1168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Tupelo Tupelo 9.2/10 Wonderful (604) "Great location and clean, comfortable hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) richard £84 includes taxes & fees 19 Nov - 20 Nov [](https://www.expedia.co.uk/Tupelo-Hotels-Tru-By-Hilton-Tupelo.h72278514.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598927/abb81802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598927/7cef7a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598927/6266d921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598927/4e43e467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Memphis/Southaven, MS Southaven 8.6/10 Excellent (1001) "Parking , shopping and food near" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Whitney £77 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Memphis-Hotels-Hilton-Garden-Inn-MemphisSouthaven.h1598927.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/3000000/2960000/2958800/2958793/969f44da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2960000/2958800/2958793/bca898d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/3000000/2960000/2958800/2958793/f9830ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2960000/2958800/2958793/f3830c25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Jackson/Flowood (Airport Area) MS Flowood 9.0/10 Wonderful (1005) "We stayed here last year for band competition and it was awesome as well. Very helpful front desk and it’s in the middle of good food and shopping. It was already in great shape last year but it looks like they just renovated the rooms and they were so very nice. Bed was very comfortable too. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lauren £87 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Jackson-Hotels-Hampton-Inn-JacksonFlowood.h2958793.Hotel-Information) ![3 restaurants, breakfast, lunch, dinner served; seafood ](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/86740aab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/0d77dc8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/3923ebb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/5c21d6dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Silver Slipper Casino & Hotel - Adults Only Bay St Louis 8.6/10 Excellent (1002) "Clean room & friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marilyn £65 includes taxes & fees 3 Dec - 4 Dec [](https://www.expedia.co.uk/Biloxi-Hotels-Silver-Slipper-Casino-Hotel.h12685296.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/46000000/45770000/45764800/45764716/783375ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free on-the-go breakfast ](https://images.trvl-media.com/lodging/46000000/45770000/45764800/45764716/9485a76d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45770000/45764800/45764716/d71c754f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/46000000/45770000/45764800/45764716/86aa793b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Jackson/Pearl, MS Pearl 8.8/10 Excellent (846) "Safe area, very clean rooms and staff was friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alyssa £88 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Jackson-Hotels-Home2-Suites-By-Hilton-JacksonPearl.h45764716.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/58000000/57790000/57787800/57787752/d13387bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/58000000/57790000/57787800/57787752/82cc7f29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/58000000/57790000/57787800/57787752/74bb001a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/58000000/57790000/57787800/57787752/5d17839d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel DeSoto Olive Branch 9.0/10 Wonderful (1156) "Pretty Good hotel and great location " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Pablo A £58 includes taxes & fees 12 Nov - 13 Nov [](https://www.expedia.co.uk/Olive-Branch-Hotels-Hotel-DeSoto.h57787752.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/46d9ec38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/ef67498d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/5c34c1ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/d46b15da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Oxford Oxford 9.2/10 Wonderful (885) "Nice place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lee £79 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Oxford-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Oxford.h39577074.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557655/bff72e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557655/9df85b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557655/4ca21e3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557655/435a39d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express and Suites Winona North by IHG Winona 8.2/10 Very good (667) "Staff were friendly and helpful. Beds were comfortable. Only complaint was shower head, only center holes gave water and pressure was low. We will stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia Mahoney £99 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Grenada-Hotels-Holiday-Inn-Express-And-Suites-Winona-North.h3557655.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19®ionId=226&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Mississippi-Spa-Hotels.0-0-d226-tSpaHotels.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Mississippi-Spa-Hotels.0-0-d226-tSpaHotels.Hotel-Filter-Destinations) ## Top Mississippi Hotel Reviews ![The Hotel Legends](//images.trvl-media.com/lodging/45000000/44560000/44550300/44550296/4393bc4f_y.jpg) ### The Hotel Legends 10/10 Excellent "Always a wonderful stay" [](https://expedia.co.uk/Biloxi-Hotels-The-Hotel-Legends.h44550296.Hotel-Information) ![Hard Rock Hotel & Casino Biloxi](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731566/7e1bb110_y.jpg) ### Hard Rock Hotel & Casino Biloxi 10/10 Excellent "Easy to get to, staff helpful and friendly, room clean and spacious, and won at the casino." [](https://expedia.co.uk/Biloxi-Hotels-Hard-Rock-Hotel-Casino-Biloxi.h1731566.Hotel-Information) ![Imperial Suites - Adults Only](//images.trvl-media.com/lodging/88000000/87900000/87891700/87891649/0f6c03ad_y.jpg) ### Imperial Suites - Adults Only 10/10 Excellent "Fireplace I couldn't find the switch to turn it on. " [](https://expedia.co.uk/Jackson-Hotels-Imperial-Suites.h87891649.Hotel-Information) ![IP Casino Resort Spa - Biloxi](//images.trvl-media.com/lodging/1000000/90000/85100/85080/e0a1ead8_y.jpg) ### IP Casino Resort Spa - Biloxi 10/10 Excellent "clean room friendly staff and a great experience!!" [](https://expedia.co.uk/Biloxi-Hotels-IP-Casino-Resort-Spa-Biloxi.h85080.Hotel-Information) ![Margaritaville Resort Biloxi](//images.trvl-media.com/lodging/16000000/15610000/15602500/15602500/b9c2b2c6_y.jpg) ### Margaritaville Resort Biloxi 10/10 Excellent "Beautiful rooms. Breakfast is not free, but it is delicious and worth it. The arcade was a blast. Too cool outside for the pool during our 3 day stay. " [](https://expedia.co.uk/Biloxi-Hotels-Margaritaville-Resort-Biloxi.h15602500.Hotel-Information) ![Palace Casino Resort](//images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/6049152a_y.jpg) ### Palace Casino Resort 10/10 Excellent "Very nice hotel great foid" [](https://expedia.co.uk/Biloxi-Hotels-Palace-Casino-Resort.h1652862.Hotel-Information) ![avid hotel Memphis - Southaven by IHG](//images.trvl-media.com/lodging/69000000/68690000/68688800/68688725/ea72589d_y.jpg) ### avid hotel Memphis - Southaven by IHG 10/10 Excellent "Great " [](https://expedia.co.uk/Memphis-Hotels-Avid-Hotels-Memphis-Southaven.h68688725.Hotel-Information) ![Motel 6 Biloxi, MS - Beach](//images.trvl-media.com/lodging/1000000/1000000/996200/996160/c051e826_y.jpg) ### Motel 6 Biloxi, MS - Beach 10/10 Excellent "Everything was good " [](https://expedia.co.uk/Biloxi-Hotels-Motel-6-Biloxi.h996160.Hotel-Information) ![Golden Nugget Biloxi](//images.trvl-media.com/lodging/1000000/30000/22300/22267/0e82f306_y.jpg) ### Golden Nugget Biloxi 10/10 Excellent "The room was great! We loved the decor and the nice view! 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