Title: Misiliscemi Holidays 2026 from £261 | Expedia.co.uk [Hotels in Misiliscemi](https://expedia.co.uk/Misiliscemi-Hotels.d919192130721861632.Travel-Guide-Hotels)[Holiday Rentals in Misiliscemi](https://expedia.co.uk/Misiliscemi-Holiday-Rentals.d919192130721861632.Travel-Guide-HolidayRentals)[Misiliscemi Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Misiliscemi.d919192130721861632.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Misiliscemi Holidays from £261 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ## Top Misiliscemi Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![I vicini della cattedrale](https://images.trvl-media.com/lodging/23000000/22470000/22466800/22466722/7e4a44c8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### I vicini della cattedrale Palermo Historical Center Save 100% on your flight £261 per person 24 Jun - 29 Jun just found Return flight included London (LON) to Palermo (PMO) 8.4/10 Very Good! (72 reviews) Property was in an excellent location but it doesn’t have elevators and it was on a very uncomfortable second level with narrow stairs, so going up and down was uncomfortable Reviewed on 22 Jun 2025 ![The Signature Level at Grand Palladium Sicilia Resort & Spa](https://images.trvl-media.com/lodging/43000000/42030000/42025800/42025780/de48ab7f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Signature Level at Grand Palladium Sicilia Resort & Spa Save 100% on your flight £1,379 per person 12 Jun - 19 Jun found 20 hours ago Return flight included Manchester (MAN) to Palermo (PMO) 9.4/10 Exceptional! (17 reviews) The drinking glasses were dirty most of the time. That was disappointing. The staff were lovely and pleasant. Dinner timings and options were limited. We were signature level and would have expected options for sea view, but those seemed to only be for the main building Food was okay. Reviewed on 7 Oct 2025 ![Agriturismo Al Poggetto](https://images.trvl-media.com/lodging/3000000/2530000/2528700/2528611/86961382_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Agriturismo Al Poggetto Save 100% on your flight £262 per person 24 Jun - 29 Jun just found Return flight included London (LON) to Palermo (PMO) 7.2/10 Good! (15 reviews) ![Baia dei Mulini Resort & Spa](https://images.trvl-media.com/lodging/2000000/1170000/1169400/1169328/903b198b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Baia dei Mulini Resort & Spa Save 100% on your flight £586 per person 7 Jun - 14 Jun found 22 hours ago Return flight included London (LON) to Palermo (PMO) 7.8/10 Good! (20 reviews) Only there one night. Everything was fine Reviewed on 1 Sept 2025 ![MClub Cala Regina](https://images.trvl-media.com/lodging/2000000/1620000/1619900/1619805/2339e12a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### MClub Cala Regina Save 100% on your flight £686 per person 25 Jun - 30 Jun found 1 hour ago Return direct flight included London (LON) to Palermo (PMO) 8/10 Very Good! (16 reviews) The property was dated and room smelled of smoke. Reviewed on 9 Sept 2021 ## Top hotels in Misiliscemi ![Agriturismo Vultaggio](https://images.trvl-media.com/lodging/6000000/5370000/5361300/5361288/7c8f3551_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Agriturismo Vultaggio Contrada Misiliscemi, 4 Guarrato Misiliscemi TP Fully refundableReserve now, pay when you stay £128 16 Apr - 17 Apr includes taxes & fees 8.6/10 Excellent! (49 reviews) Comfortable rooms, friendly and professional staff, wonderful breakfast. Impressive pool. Reviewed on 24 Sept 2025 [](https://expedia.co.uk/Hotel-Search?startDate=16%2F04%2F2026&endDate=17%2F04%2F2026&selected=5361288&PinnedHotelID=5361288&HadPinnedHotel=true®ionId=919192130721861632) ![Hotel Mira Spiaggia](https://images.trvl-media.com/lodging/2000000/1090000/1089300/1089281/1f4724be_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Mira Spiaggia Via Lungomare 6 San Vito Lo Capo TP £55 20 Apr - 21 Apr includes taxes & fees 8.2/10 Very Good! (217 reviews) Proximity to beach and great breakfast!! Reviewed on 1 Nov 2025 [](https://expedia.co.uk/Hotel-Search?startDate=20%2F04%2F2026&endDate=21%2F04%2F2026&selected=1089281&PinnedHotelID=1089281&HadPinnedHotel=true®ionId=919192130721861632) ![Residence La Gancia](https://images.trvl-media.com/lodging/4000000/3820000/3811200/3811156/bf38e02d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Residence La Gancia Piazza Mercato del Pesce Trapani TP £91 11 Apr - 12 Apr includes taxes & fees 9.4/10 Exceptional! (359 reviews) 바다 바로 옆. 전자레인지 있음. 객실 깨끗. Reviewed on 13 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=11%2F04%2F2026&endDate=12%2F04%2F2026&selected=3811156&PinnedHotelID=3811156&HadPinnedHotel=true®ionId=919192130721861632) [See all 3,814 properties in Misiliscemi](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=03%2F04%2F2026&endDate=04%2F04%2F2026®ionId=919192130721861632) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### What to do in Misiliscemi ![Guided tour of the salt pans of Trapani and the Salt Museum](https://mediaim.expedia.com/localexpert/46336714/21ca33d2-b8d7-4378-9ad7-d67a11d04f70.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Guided tour of the salt pans of Trapani and the Salt Museum £16 per adult [](https://expedia.co.uk/things-to-do/guided-tour-of-the-salt-pans-of-trapani-and-the-salt-museum.a46336714.activity-details) ![Marsala: Winery Tour with Wine Tasting and Local Products](https://mediaim.expedia.com/localexpert/45946886/b61ec7f0-74de-4c2e-882d-e224e586fff7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Marsala: Winery Tour with Wine Tasting and Local Products £17 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/marsala-winery-tour-with-wine-tasting-and-local-products.a45946886.activity-details) ![Egadi Islands Excursion by Inflatable Boat](https://mediaim.expedia.com/localexpert/46463470/ed110365-8c49-4b2a-a5b0-730d2759cbcb.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Egadi Islands Excursion by Inflatable Boat £52 per adult [](https://expedia.co.uk/things-to-do/egadi-islands-excursion-by-inflatable-boat.a46463470.activity-details) [See all activities in Misiliscemi](https://expedia.co.uk/things-to-do/search?rid=919192130721861632) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app