
Misiliscemi Holidays from £160
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Top Misiliscemi Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.

Hotel Vecchio Borgo
Politeama
£160
per person
11 Dec - 15 Dec
found 21 hours ago
Return flight included
London (LON) to Palermo (PMO)
8/10 Very good! (363 reviews)
This is not a 4 star hotel. I had a nice room and the staff is helpful. Breakfast is mostly sweets, no fruit. The elevator near my room makes loud groaning noises when in use. But the location is poor, some distance from the tourist area down twisted poorly maintained streets. I got lost twice trying to find it again. Taxis charge 20 euros to take you less than a mile to the main tourist area. Nearby restaurants are for locals with nothing in English. I just can't recommend it because of the location. Otherwise OK.
Reviewed on 18 May 2026


Eurostars Centrale Palace
Palermo Historical Center
£455
per person
11 Nov - 15 Nov
found 1 day ago
Return flight included
Manchester (MAN) to Palermo (PMO)
8.4/10 Very good! (1,003 reviews)
A very nice hotel. Perfectly situated for attractions of the city and certainly for restaurants day and night. The building is actually a centuries old palace and many of the common rooms reflect this with nice decor and antique furnishings. A rooftop bar and restaurant compliment the high standards of the establishment. Service at reception, breakfast and staff in general was similarly always very good.
Our standard room was a good size with a/c, fridge, TV, safe and tea and coffee facilities, very comfortable.Buffet breakfast was extensive, some hot choices, bacon, sausage, eggs, a considerable variety of cold meats, cheeses, yogurts and breads and cakes. Fresh fruit, tea, variety of coffees and cold juices completed and excellent start to the day.
Reviewed on 30 Sept 2026

La Serenissima Hotel
Palermo Historical Center
£236
per person
11 Dec - 15 Dec
found 21 hours ago
Return flight included
London (LON) to Palermo (PMO)
8.6/10 Excellent! (159 reviews)
⭐️ Beautiful hotel in the heart of Palermo — but think twice about driving!
The hotel itself is beautiful and perfectly located in Palermo’s historic centre, with easy access to the nightlife, sights and cruise port. Our room was huge, with a separate bedroom and living/family-room area, and had everything we needed. We would absolutely stay here again.
My biggest caution is arriving with a rental car. The hotel is within the ZTL, and Google Maps struggled to navigate us through the extremely narrow and restricted streets. Make sure you carefully read the hotel’s instructions and provide your licence plate and driver information in advance.
We were given contact information for several garages, but had difficulty getting responses and initially received very little assistance from the hotel. After I expressed my frustration through Expedia, the hotel stepped in and arranged the parking for us, which I appreciated. I do think the arrival, ZTL and parking process could be explained more clearly and proactively.
The area is lively and noisy at night, but that’s also part of the charm of staying right in historic Palermo. Bring earplugs if you’re a light sleeper, then step outside and enjoy the nightlife!
Overall, a wonderful hotel in a fantastic location. I would happily stay again—but next time I’d arrive by taxi rather than rental car! 🇮🇹
Reviewed on 29 Sept 2026

Bellaroto Suite & Spa - Charming Boutique Rooms
Palermo Historical Center
£377
per person
13 Nov - 16 Nov
found 1 day ago
Return direct flight included
London (LON) to Palermo (PMO)
9.6/10 Exceptional! (117 reviews)
Uniquely charming old Palazzo ideally located within a few minutes walk of many Palermo attractions. Small common area is just outside the rooms, a good place to enjoy tea, coffee, fruit and biscuits, and to meet other guests. Good restaurant suggestions. Room quiet despite busy neighborhood. Older or less able guests need to know that access is possible only via outside staircase, expect no help with bags.
Reviewed on 21 Sept 2026
Top hotels in Misiliscemi

Albergo Vittoria
Via Francesco Crispi 4 Trapani TP
£87
2 Oct - 3 Oct
includes taxes & fees

SEAWATER HOTEL BIO & BEAUTY SPA
Via Trapani 330 Marsala TP
£51
1 Nov - 2 Nov
includes taxes & fees
9/10 Wonderful! (71 reviews)
"Great place. Clean, friendly staff and great pool. Would definitely go back. Thanks for the great experience."
Reviewed on 30 Jun 2026

Almar Giardino di Costanza Mazara del Vallo Resort & Spa
Via Salemi 100, Km 7 Mazara del Vallo TP
Fully refundableReserve now, pay when you stay
£187
18 Oct - 19 Oct
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Misiliscemi attractions
Promoter Kinisia
You can take time to visit Promoter Kinisia during your travels to Misiliscemi.
What to do in Misiliscemi

Mini Cruise to Favignana and Levanzo with lunch on board
£34
per adult

Guided tour of the salt pans of Trapani and the Salt Museum
£24
per adult

Egadi Islands Boat Tour: Favignana & Levanzo from Trapani
£77
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.










