Title: Midsize Isla Santa Maria Car Hire | Expedia.co.uk ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Midsize Car Hire Companies in Isla Santa Maria [Become a member for free](https://expedia.co.uk/member-price?rfrr=TG.CM) and get more than just a booking discount. Members also earn points towards their next trip. Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more. Enjoy maximum flexibility with penalty-free cancellation on most car rentals. ## Find Cheap Midsize Car Deals for Isla Santa Maria \* Price found within the past 6 days. Click for updated prices. ### Don't see what you're looking for? See all car hire in Isla Santa Maria [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Isla%20Santa%20Maria,%20Biob%C3%ADo,%20Chile&dpln=6101241&date1=23/09/2025&date2=25/09/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ## Midsize Car Hire Information | Car type: | Midsize | | --- | --- | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | - Experience new places with Expedia ### Find Other Car Classes in Isla Santa Maria - [Mini car hire in Isla Santa Maria](https://expedia.co.uk/Mini-Car-Rentals-In-Isla-Santa-Maria.d6101241-tMini.Car-Rental-Guide-Class) - [Economy car hire in Isla Santa Maria](https://expedia.co.uk/Economy-Car-Rentals-In-Isla-Santa-Maria.d6101241-tEconomy.Car-Rental-Guide-Class) - [Compact car hire in Isla Santa Maria](https://expedia.co.uk/Compact-Car-Rentals-In-Isla-Santa-Maria.d6101241-tCompact.Car-Rental-Guide-Class) - [Standard car hire in Isla Santa Maria](https://expedia.co.uk/Standard-Car-Rentals-In-Isla-Santa-Maria.d6101241-tStandard.Car-Rental-Guide-Class) - [Fullsize car hire in Isla Santa Maria](https://expedia.co.uk/Fullsize-Car-Rentals-In-Isla-Santa-Maria.d6101241-tFullsize.Car-Rental-Guide-Class) - [Premium car hire in Isla Santa Maria](https://expedia.co.uk/Premium-Car-Rentals-In-Isla-Santa-Maria.d6101241-tPremium.Car-Rental-Guide-Class) - [Luxury car hire in Isla Santa Maria](https://expedia.co.uk/Luxury-Car-Rentals-In-Isla-Santa-Maria.d6101241-tLuxury.Car-Rental-Guide-Class) - [Convertible car hire in Isla Santa Maria](https://expedia.co.uk/Convertible-Car-Rentals-In-Isla-Santa-Maria.d6101241-tConvertible.Car-Rental-Guide-Class) - [Minivan car hire in Isla Santa Maria](https://expedia.co.uk/Minivan-Car-Rentals-In-Isla-Santa-Maria.d6101241-tMinivan.Car-Rental-Guide-Class) - [Van car hire in Isla Santa Maria](https://expedia.co.uk/Van-Car-Rentals-In-Isla-Santa-Maria.d6101241-tVan.Car-Rental-Guide-Class) - 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