Title: Isla Santa Maria Travel Guide: Best of Isla Santa Maria, Biobío Travel 2026 | Expedia.co.uk [Hotels in Isla Santa Maria](https://expedia.co.uk/Isla-Santa-Maria-Hotels.d6101241.Travel-Guide-Hotels)[Holiday Rentals in Isla Santa Maria](https://expedia.co.uk/Isla-Santa-Maria-Holiday-Rentals.d6101241.Travel-Guide-HolidayRentals)[Flights to Isla Santa Maria](https://expedia.co.uk/Cheap-Flights-To-Isla-Santa-Maria.d6101241.Travel-Guide-Flights)[Isla Santa Maria Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Isla-Santa-Maria.d6101241.Car-Hire-Guide)[Isla Santa Maria Holidays](https://expedia.co.uk/Isla-Santa-Maria.d6101241.Holidays-City-Breaks) # Isla Santa Maria Travel Guide ## Tourist Guide ## Visit Isla Santa Maria - Top hotels in Isla Santa Maria - Top Holiday Rentals in Isla Santa Maria ![Hotel Arauco](https://images.trvl-media.com/lodging/34000000/33820000/33810700/33810611/7207a990_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Arauco Ruta 160, Km. 65 Carampangue - Arauco Arauco Arauco Stay at this hotel in Arauco. Enjoy a 24-hour front desk. [Get rates](https://expedia.co.uk/Hotel-Search?startDate=06%2F01%2F2026&endDate=07%2F01%2F2026&selected=33810611&PinnedHotelID=33810611&HadPinnedHotel=true®ionId=6101241) [](https://expedia.co.uk/Hotel-Search?startDate=06%2F01%2F2026&endDate=07%2F01%2F2026&selected=33810611&PinnedHotelID=33810611&HadPinnedHotel=true®ionId=6101241) ![Hotel Piedra Cruz](https://images.trvl-media.com/lodging/124000000/123390000/123389700/123389606/1a8bd5ba_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Piedra Cruz C. Gabriela Mistral Arauco Bío Bío Fully refundableReserve now, pay when you stay £36 29 Dec - 30 Dec Stay at this hotel in Arauco. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Parque Isidora Cousiño and Museo Histórico de Lota ... [](https://expedia.co.uk/Hotel-Search?startDate=29%2F12%2F2025&endDate=30%2F12%2F2025&selected=123389606&PinnedHotelID=123389606&HadPinnedHotel=true®ionId=6101241) [See all 2 properties in Isla Santa Maria](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=24%2F12%2F2025&endDate=25%2F12%2F2025®ionId=6101241) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![HOTEL EL DORADO](https://images.trvl-media.com/lodging/85000000/84160000/84154400/84154323/w2996h1688x4y0-e714372f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### HOTEL EL DORADO Barros Arana Concepción Bío Bío Stay at this business-friendly aparthotel in Concepción. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Plaza de la Independencia and ... 8.2/10 Very Good! (54 reviews) The room was clean. The staff was very friendly and helpful. Good location. Good WiFi connection. Good breakfast. Overall, a pleasant experience. Reviewed on 20 Nov 2025 [](https://expedia.co.uk/Concepcion-Hotels-HOTEL-EL-DORADO.h84154323.Hotel-Information) ![Beautiful house Villa Cocholgue](https://images.trvl-media.com/lodging/20000000/19490000/19487600/19487522/beaa340c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Beautiful house Villa Cocholgue Cocholgüe Tomé, Región del Bío Bío Stay at this beach holiday home in Tome. Enjoy private pools, breakfast (surcharge) and a pool table. Popular attractions Cochologue Beach and El Morro Beach ... 2/10 (1 review) Glenn Totally fraudulent Reviewed on 29 Nov 2023 [](https://expedia.co.uk/Tome-Hotels-Beautiful-House-Villa-Cocholgue.h19487522.Hotel-Information) ![NM Apart Tucapel](https://images.trvl-media.com/lodging/115000000/114950000/114940700/114940637/81935b46_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### NM Apart Tucapel Tucapel 664 Concepción Bío Bío Stay at this apartment in Concepción. Enjoy free Wi-Fi and a 24-hour front desk. Popular attractions Plaza de la Independencia and Catedral de la Santisima Concepcion ... [](https://expedia.co.uk/Concepcion-Hotels-NM-Apart-Tucapel.h114940637.Hotel-Information) [See all 185 properties in Biobío](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248635997965342&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Isla Santa Maria hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6101241&startDate=2025-12-23&endDate=2025-12-24)[23 Dec - 24 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6101241&startDate=2025-12-23&endDate=2025-12-24) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6101241&startDate=2025-12-24&endDate=2025-12-25)[24 Dec - 25 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6101241&startDate=2025-12-24&endDate=2025-12-25) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6101241&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025)[26 Dec - 28 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6101241&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6101241&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026)[2 Jan - 4 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6101241&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - [5 Star Hotels in Concepción ](https://www.expedia.co.uk/5Star-Concepcion-Hotels.s50-0-d790.Travel-Guide-Filter-Hotels) - [Arauco Hotels ](https://www.expedia.co.uk/Arauco-Hotels.d3000374698.Travel-Guide-Hotels) - [Cabrero Hotels ](https://www.expedia.co.uk/Cabrero-Hotels.d6359030.Travel-Guide-Hotels) - [Cañete Hotels ](https://www.expedia.co.uk/Canete-Hotels.d3000445543.Travel-Guide-Hotels) - [Concepción Hotels ](https://www.expedia.co.uk/Concepcion-Hotels.d790.Travel-Guide-Hotels) - [Contulmo Hotels ](https://www.expedia.co.uk/Contulmo-Hotels.d3000400358.Travel-Guide-Hotels) - [Coronel Hotels ](https://www.expedia.co.uk/Coronel-Hotels.d3000006421.Travel-Guide-Hotels) - [Curanilahue Hotels ](https://www.expedia.co.uk/Curanilahue-Hotels.d3000006418.Travel-Guide-Hotels) - [Biobío Hotels ](https://www.expedia.co.uk/Destinations-In-Biobio.d553248635997965342.Hotel-Destinations) - [Dichato Hotels ](https://www.expedia.co.uk/Dichato-Hotels.d553248635964996671.Travel-Guide-Hotels) - [La Florida Hotels ](https://www.expedia.co.uk/La-Florida-Hotels.d178528.Travel-Guide-Hotels) - [Laja Hotels ](https://www.expedia.co.uk/Laja-Hotels.d3000006374.Travel-Guide-Hotels) - [Laraquete Hotels ](https://www.expedia.co.uk/Laraquete-Hotels.d3000006373.Travel-Guide-Hotels) - [Lebu Hotels ](https://www.expedia.co.uk/Lebu-Hotels.d6252686.Travel-Guide-Hotels) - [Los Angeles Hotels ](https://www.expedia.co.uk/Los-Angeles-Hotels.d500226.Travel-Guide-Hotels) - [Lota Hotels ](https://www.expedia.co.uk/Lota-Hotels.d3000374705.Travel-Guide-Hotels) - [Negrete Hotels ](https://www.expedia.co.uk/Negrete-Hotels.d3000006337.Travel-Guide-Hotels) - [San Pedro de la Paz Hotels ](https://www.expedia.co.uk/San-Pedro-De-La-Paz-Hotels.d3000006271.Travel-Guide-Hotels) - [Tome Hotels ](https://www.expedia.co.uk/Tome-Hotels.d6353212.Travel-Guide-Hotels) - [Yumbel Hotels ](https://www.expedia.co.uk/Yumbel-Hotels.d3000006256.Travel-Guide-Hotels) - [Flights to Los Angeles ](https://www.expedia.co.uk/Cheap-Flights-To-Los-Angeles.d500226.Travel-Guide-Flights) - [Flights to Lota ](https://www.expedia.co.uk/Cheap-Flights-To-Lota.d3000374705.Travel-Guide-Flights) - [Flights from London (LHR) to Concepcion (CCP) ](https://www.expedia.co.uk/lp/flights/lhr/ccp/london-to-concepcion) - [Flights from London (LON) to Concepcion (CCP) ](https://www.expedia.co.uk/lp/flights/lon/ccp/london-to-concepcion) - [Flights from Santiago (SCL) to Concepcion (CCP) ](https://www.expedia.co.uk/lp/flights/scl/ccp/santiago-to-concepcion) - [Visit Cabrero ](https://www.expedia.co.uk/Cabrero.dx6359030) - [Visit Concepción ](https://www.expedia.co.uk/Concepcion.dx790) - [Visit Curanilahue ](https://www.expedia.co.uk/Curanilahue.dx3000006418) - [Estadio Municipal de Concepcion ](https://www.expedia.co.uk/Estadio-Municipal-De-Concepcion-Concepcion.d6101214.Attraction) - [Visit Hualpén ](https://www.expedia.co.uk/Hualpen.dx553248635943692184) - [La Florida Holidays ](https://www.expedia.co.uk/La-Florida.d178528.Holidays-City-Breaks) - [Visit Lebu ](https://www.expedia.co.uk/Lebu.dx6252686) - [Lota Holidays ](https://www.expedia.co.uk/Lota.d3000374705.Holidays-City-Breaks) - [Visit Lota ](https://www.expedia.co.uk/Lota.dx3000374705) - [Visit San Pedro de la Paz ](https://www.expedia.co.uk/San-Pedro-De-La-Paz.dx3000006271) - [Visit Tome ](https://www.expedia.co.uk/Tome.dx6353212) - [Apex Car Rentals Rental Cars in Los Álamos ](https://www.expedia.co.uk/Apex-Car-Rentals-Car-Rentals-In-Los-Alamos.d553248635943692183-c1064.Car-Rental-Guide-Suppliers) - [Car hire Concepción ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Concepcion.d790.Car-Hire-Guide) - [Car hire Lota ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Lota.d3000374705.Car-Hire-Guide) - [Guerin Rental Cars in Los Álamos ](https://www.expedia.co.uk/Guerin-Car-Rentals-In-Los-Alamos.d553248635943692183-c1129.Car-Rental-Guide-Suppliers) - [Sr Rent A Car Rental Cars in Los Álamos ](https://www.expedia.co.uk/SR-Rent-A-Car-Car-Rentals-In-Los-Alamos.d553248635943692183-c1077.Car-Rental-Guide-Suppliers) - [Sicily By Car Rental Cars in Los Álamos ](https://www.expedia.co.uk/Sicily-By-Car-Car-Rentals-In-Los-Alamos.d553248635943692183-c1048.Car-Rental-Guide-Suppliers) - [Thai Cars Rental Cars in Los Álamos ](https://www.expedia.co.uk/Thai-Cars-Car-Rentals-In-Los-Alamos.d553248635943692183-c1027.Car-Rental-Guide-Suppliers) - [La Florida Holiday Rentals ](https://www.expedia.co.uk/La-Florida-Holiday-Rentals.d178528.Travel-Guide-HolidayRentals) - [Los Angeles Holiday Rentals ](https://www.expedia.co.uk/Los-Angeles-Holiday-Rentals.d500226.Travel-Guide-HolidayRentals) - Cities near Isla Santa Maria ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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