Messias Targino is a small, quiet town, and the best area to stay is generally in the central part, close to the main square and municipal buildings.
This central area offers the most convenience, as it's where you'll find the limited selection of guesthouses and local eateries. The main square, often called Praça Central, is a focal point for local life, especially in the evenings, and it's typically surrounded by the town's key amenities.
For travellers seeking a tranquil escape, the central area provides easy access to the town's simple charm.