Mesi Holidays from £352

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Your Mesi Holiday

Lock in a Mesi holiday package and get set to experience this exciting city the stress-free way. Consider staying in the neighbourhood of Myli, which is great for views and hiking. If your trip to Mesi includes a little sightseeing, check out renowned attractions like Rethymnon Town Hall, Rethymnon Lighthouse and Arkadi Monastery. Check out Expedia's wide range of travel options and begin planning your dream holiday to Mesi today.

Top Mesi Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Infinity City Boutique Hotel

Infinity City Boutique Hotel

4 out of 5
Price was £526, price is now £352 per person
£352
per person
28 Nov - 5 Dec
found 23 hours ago
Return direct flight included
Manchester (MAN) to Heraklion (HER)
8.8/10 Excellent! (356 reviews)
Excellent hotel within walking distance of the port for our short stop over in Heraklion . Staff very helpful and allowed us to have early breakfast before our ferry .

Reviewed on 6 Sept 2026

Lagon Life Spirit Design Villas - Adults Only

Lagon Life Spirit Design Villas - Adults Only

4 out of 5
Price was £1,144, price is now £443 per person
£443
per person
28 Nov - 5 Dec
found 23 hours ago
Return direct flight included
Manchester (MAN) to Chania (CHQ)
9.8/10 Exceptional! (15 reviews)
Excellent accommodation, close to Chania if you have a car, and close to the hotel that operates the villas. Very spacious villas, pool, very good views from the balcony. The mini-kitchen and the big fridge were very welcome - enough to cook a quick meal and store whatever you bring from the city and surrounding areas. The cleaning staff are very attentive, and seem to always be in a good mood - adds positively to the atmosphere. You can make use of the hotel services like spa/massage. You may want to bring earplugs with you if you are a sensitive sleeper - the cocks from the nearby farm were loud from ~06:00.

Reviewed on 25 Oct 2026

Vespera City Hotel

Vespera City Hotel

3 out of 5
Save 100% on your flight
Price was £706, price is now £387 per person
£387
per person
28 Nov - 5 Dec
found 23 hours ago
Return direct flight included
Manchester (MAN) to Heraklion (HER)
9.2/10 Wonderful! (44 reviews)

Dimargio Luxury Hotel & Spa

Dimargio Luxury Hotel & Spa

5 out of 5
Save 100% on your flight
Price was £715, price is now £481 per person
£481
per person
28 Nov - 5 Dec
found 23 hours ago
Return direct flight included
Manchester (MAN) to Heraklion (HER)
9.8/10 Exceptional! (61 reviews)
Wonderful front desk staff and beautiful place

Reviewed on 20 Oct 2026

Domus Renier Boutique Hotel, Member of Domus Elegance Collection

Domus Renier Boutique Hotel, Member of Domus Elegance Collection

4 out of 5
Old Town Chania
Save 100% on your flight
Price was £701, price is now £493 per person
£493
per person
28 Nov - 5 Dec
found 23 hours ago
Return direct flight included
Manchester (MAN) to Chania (CHQ)
10/10 Exceptional! (249 reviews)

Mesi Essential Information

Language
Greek
Currency
Euros
Local Welcome
Ya su
Local Goodbye
Yiá sou
Closest Airport
Ioannis Daskalogiannis Airport (CHQ)
Max Temp Winter
16ºC
Max Temp Summer
29ºC
Top Sights
Fortezza Castle, Rethymnon Cathedral and Erofili Theatre

Top hotels in Mesi

Nautilux Rethymno by Mage Hotels

Nautilux Rethymno by Mage Hotels

5 out of 5
Australon Polemiston 23 Rethymno Crete
Fully refundableReserve now, pay when you stay
The price is £179 per night from 31 Oct to 1 Nov
£179
31 Oct - 1 Nov
includes taxes & fees
9.6/10 Exceptional! (426 reviews)
"Over all hotel is nice , Everyone working here was nice and kind . Anyhow for 5 star hotel shower enclosure is only 2 stars…. It is no door from living area to the bathroom,so it is crazy cold when you get out from the shower,and enclosure itself is ridiculously uncomfortable, Other thing -guests ..."

Reviewed on 26 Oct 2026

Nautilux Rethymno by Mage Hotels
Grecotel Marine Palace & Aqua Park

Grecotel Marine Palace & Aqua Park

4 out of 5
Panormo Mylopotamos Crete Island
Fully refundableReserve now, pay when you stay
The price is £121 per night from 5 Nov to 6 Nov
£121
5 Nov - 6 Nov
includes taxes & fees
9/10 Wonderful! (119 reviews)
"We had an amazing time everything from the transfers to and from the airport to the hotel, to the hotel itself just couldn’t fault anything. The staff couldn’t do enough for you and they were so friendly. This was the first time going all inclusive we couldn’t have chosen a better place the food ..."

Reviewed on 13 Oct 2026

Grecotel Marine Palace & Aqua Park
The Royal Senses Resort & Spa Crete, Curio Collection Hilton

The Royal Senses Resort & Spa Crete, Curio Collection Hilton

5 out of 5
58 Km Herakliou Mylopotamos Crete
The price is £213 per night from 4 Nov to 5 Nov
£213
4 Nov - 5 Nov
includes taxes & fees
9.4/10 Exceptional! (153 reviews)
"A fantastic hotel with an outstanding team who truly go above and beyond to make you feel welcome. The attention to detail is exceptional, and every aspect of the experience is thoughtfully taken care of. From arrival to checkout, the staff make every effort to ensure you have a memorable and enjoyable ..."

Reviewed on 28 Oct 2026

The Royal Senses Resort & Spa Crete, Curio Collection Hilton
See all 4,645 properties in Mesi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in Mesi

Rethymno: Melidoni Cave and Arkadi Monastery Half-Day Trip

From Rethymno: Arkadi Monastery, Melidoni Cave and Margarites

£21
per adult
From Rethymno: Arkadi Monastery, Melidoni Cave and Margarites
Arkadi, Melidoni, Margarites Half day

Arkadi, Melidoni, Margarites, olive oil factory

£21
per adult
Arkadi, Melidoni, Margarites, olive oil factory
Elafonisi Beach Trip from Rethymno

Elafonisi Beach Trip from Rethymno

£42
per adult
Elafonisi Beach Trip from Rethymno
See all activities in Mesi

Frequently asked questions

How much does a Mesi travel package cost?
Our Mesi travel packages, which start at just £352, are an awesome way to save precious money. Pick and choose your favourite hotels, flights and rental car to create your dream itinerary.
If I'm not able to travel, can I cancel my Mesi travel package?
You can cancel your Mesi booking if your plans have been upended. Whether you'll incur a penalty or not depends on your hotel, airline or car rental company. It may be possible to change or cancel for free if you booked in the last 24 hours. Head to our Customer Service Portal to learn more.
How do I get a cheap travel package to Mesi?
Our Mesi travel packages promise plenty of savings for the savvy explorer. For the best deals, simply combine your hotel, flights and rental cars into a budget-friendly package. But low prices are only the start of your next unforgettable adventure. Book with Expedia and you'll have more than 550 airlines and 1,000,000 hotel options around the globe to choose from. Whatever your style or budget, there's a travel package with your name on it.
Does Expedia offer Book Now, Pay Later Mesi holidays?
Expedia has teamed up with online lender Klarna to make your next break a bit easier on the wallet. Paying in instalments means you can spread the costs of your dream holiday, leaving you with more money to spend while you're away. Klarna has several payment plans to choose from, so you're sure to find something that fits into your budget. Check out these flexible payment options:

  • Pay monthly holidays: Klarna has convenient monthly payment plans that suit all budgets, so you can take that well-deserved holiday now.
  • Pay in instalments holidays: If you'd like to pay off your escape in multiple transactions, holidays paid in instalments might be the best option for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than all of it upfront) makes it easier to click that "book now" button, choose a low deposit holiday payment plan with Klarna.

Where should I stay in Mesi?
A holiday in Mesi wouldn't be complete without stopping by Rethimno Kart. Why not book a hotel close to this much-loved tourist attraction?
What are the top hotels in Mesi?
Casa Vitae and Theartemis Palace are among the most popular hotels in Mesi. Why not check out the facilities and rates at each and then make a decision?
How far in advance should I book my Mesi holiday?
It all depends on the air carrier, but it's usually possible to look up international airfares on Expedia up to 12 months in advance. While it's a good idea to book ahead of time, lucky travellers occasionally find a cheaper ticket just weeks before departure dates.
What does an Expedia Mesi travel package include?
Expedia has everything you need to book your Mesi getaway, but how your package is structured is entirely up to you. Pick from a combination of rental cars, flights and hotels. Chasing some tours or experiences to keep you busy? Once you've made your booking, you can add them too. Whatever your budget or style, there's a travel package to match your needs.
What should I know before booking a Mesi travel package?
You can save a tidy sum by bundling your airfares, hotels and rental cars. Once you've created your package, add on fun stuff like day tours or experiences. Your next awesome adventure is only a couple of clicks away.
Can I choose my airline with a Mesi Expedia travel package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines globally. Our packages give you the freedom to take your pick of available flight, hotel or activity options that fit your needs.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.