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16 Oct - 17 Oct
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Our top choices for Mayo Clinic Scottsdale hotels

A cluster of modern, multi-story buildings with a river in the foreground.
A dining area with a glass table, wooden chairs, and potted plants.
A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.
A golf course with a pond, a clubhouse, and a hilly backdrop.

1. Inn at Eagle Mountain

Inn at Eagle Mountain
2 mi from Mayo Clinic Scottsdale
United States
Stephanie
£114
includes taxes & fees
25 Oct - 26 Oct
Inn at Eagle Mountain
A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.
A modern hotel with a covered entrance, multiple floors, and a parking lot.
A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.
A modern lobby with a brick wall, seating area, and a flat-screen TV.

2. Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
11.1 mi from Mayo Clinic Scottsdale
United States
greg
£116
includes taxes & fees
26 Oct - 27 Oct
Hyatt Place Phoenix/Mesa
A hotel room with a bed, a desk with a computer, a chair, a sofa, and a TV.
An outdoor dining table set with chairs, string lights, and a sunset view.
A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.
A modern kitchen with a microwave, sink, and dishwasher. There is a dining area with a table and chairs, and a sofa. The room has a large window with a view of the mountains.

3. Home2 Suites by Hilton Mesa Longbow, AZ

Home2 Suites by Hilton Mesa Longbow, AZ
9.2 mi from Mayo Clinic Scottsdale
United States
Damon
£133
includes taxes & fees
1 Nov - 2 Nov
Home2 Suites by Hilton Mesa Longbow, AZ
A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.
A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.
A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.
A bar area with a long counter, multiple stools, and overhead pendant lighting.

4. Hyatt House North Scottsdale

Hyatt House North Scottsdale
8.8 mi from Mayo Clinic Scottsdale
United States
Cassie
£116
includes taxes & fees
25 Oct - 26 Oct
Hyatt House North Scottsdale
Front of property
A spacious living room with a fireplace, two grey sofas, and a patterned rug.
A spacious living room with a fireplace, a dining area with a round table, and a kitchen in the background.
A bedroom with a bed, a ceiling fan, a television, and a door.

5. Close to Hiking! Family-friendly Mesa Retreat

Close to Hiking! Family-friendly Mesa Retreat
8.5 mi from Mayo Clinic Scottsdale
£590
includes taxes & fees
26 Oct - 27 Oct
Close to Hiking! Family-friendly Mesa Retreat
A modern outdoor seating area with sofas and a central fire feature.
A modern hotel lobby with a white sofa, armchairs, a coffee table, and a dining area with chairs and a table. Large windows provide a view of the outdoors.
A hotel lobby with a tiled floor, a large chandelier, and a sign for the Arizona Ballroom.
A hotel courtyard with a swimming pool, palm trees, and a covered seating area.

6. Delta Hotels by Marriott Phoenix Mesa

Delta Hotels by Marriott Phoenix Mesa
11.6 mi from Mayo Clinic Scottsdale
United States
James
£92
includes taxes & fees
25 Oct - 26 Oct
Delta Hotels by Marriott Phoenix Mesa
A hotel lobby with a reception desk, seating area, and a large wall mural.
A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.
A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.
A hotel room with two beds, a desk, a lamp, and a window with curtains.

7. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Central Scottsdale, 5.5 mi from Mayo Clinic Scottsdale
United States
Farzana
£72
includes taxes & fees
25 Oct - 26 Oct
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
A circular fire feature with a stone border, surrounded by a landscaped garden with cacti and shrubs, under a sunset sky.
A modern bar area with seating, a digital menu display, and a beverage refrigerator.
A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and stone pillars.
A modern lobby with a central water feature, seating area, and a stone pillar.

8. Courtyard Scottsdale Salt River

Courtyard Scottsdale Salt River
7.6 mi from Mayo Clinic Scottsdale
United States
Karl
£133
includes taxes & fees
25 Oct - 26 Oct
Courtyard Scottsdale Salt River
A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.
An outdoor seating area with a fire feature, surrounded by a fence and palm trees, under a sunset sky.
A bar area with multiple seating options, a bar counter, and a television screen displaying sports.
A multi-story hotel with a flat roof and balconies, surrounded by well-maintained grass and trees.

9. Embassy Suites by Hilton Phoenix Scottsdale

Embassy Suites by Hilton Phoenix Scottsdale
11.1 mi from Mayo Clinic Scottsdale
United States
Matthew
£133
includes taxes & fees
1 Nov - 2 Nov
Embassy Suites by Hilton Phoenix Scottsdale
A modern hotel with a flat roof, large windows, and a landscaped courtyard.
A swimming pool with lounge chairs and umbrellas, surrounded by a stone wall and a building.
A hotel room with a large bed, a sofa, a small table, a chair, and a TV mounted on the wall.
View from room

10. AC Hotel by Marriott Scottsdale North

AC Hotel by Marriott Scottsdale North
Paradise Valley Village, 8.3 mi from Mayo Clinic Scottsdale
United States
Kristen
£129
includes taxes & fees
30 Oct - 31 Oct
AC Hotel by Marriott Scottsdale North
An outdoor dining area with wicker furniture and candles, overlooking a well-maintained garden and buildings.
A kitchen with a large island, granite countertops, and a mural of a desert landscape.
A hotel with a modern design, featuring a prominent entrance, a landscaped garden with a fountain, and palm trees.
A spacious lobby with a fireplace, seating area, and a dining setup.

11. Sonesta Suites Scottsdale Gainey Ranch

Sonesta Suites Scottsdale Gainey Ranch
7.6 mi from Mayo Clinic Scottsdale
Canada
Rhonda
£154
includes taxes & fees
25 Oct - 26 Oct
Sonesta Suites Scottsdale Gainey Ranch
A swimming pool surrounded by lounge chairs and palm trees, with a modern building in the background.
A bar area with a curved counter, multiple stools, and a sign reading "The Curve".
A Sheraton hotel with a modern design, featuring large windows and a prominent logo on the facade.
A hotel room with a large window offering a view of a body of water and palm trees, a desk with a chair, and a round mirror on the wall.

12. Sheraton Mesa Hotel at Wrigleyville West

Sheraton Mesa Hotel at Wrigleyville West
11.7 mi from Mayo Clinic Scottsdale
United States
Blanca
£121
includes taxes & fees
10 Nov - 11 Nov
Sheraton Mesa Hotel at Wrigleyville West
A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".
A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.
A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.
An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

13. Tru By Hilton Scottsdale Salt River

Tru By Hilton Scottsdale Salt River
5.5 mi from Mayo Clinic Scottsdale
United States
Colleen
£105
includes taxes & fees
8 Nov - 9 Nov
Tru By Hilton Scottsdale Salt River
A modern hotel with a swimming pool, sun loungers, and umbrellas.
A rooftop pool with lounge chairs and a view of mountains.
A multi-story hotel with a parking lot and a road leading to a roundabout.
A hotel room with two beds, a desk, a sofa, and a TV.

14. Hyatt Place Scottsdale - North

Hyatt Place Scottsdale - North
8.8 mi from Mayo Clinic Scottsdale
United States
Ted
£117
includes taxes & fees
25 Oct - 26 Oct
Hyatt Place Scottsdale - North
A hotel room with two beds, a desk with a chair, a TV, and a lamp.
A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.
A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.
A reception area with a stone wall, a wooden reception desk, and a modern elevator.

15. Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
6 mi from Mayo Clinic Scottsdale
United States
LAURA
£94
includes taxes & fees
1 Nov - 2 Nov
Comfort Suites Scottsdale Talking Stick Entertainment District
A resort with multiple buildings, a large pool area, and surrounding mountains.
A dining area with a table set for six, overlooking a scenic landscape.
An outdoor wedding reception with round tables set with white chairs, floral centerpieces, and a view of the city in the background.
Three people in a swimming pool with rocks and a red umbrella in the background.

16. ADERO Scottsdale Resort, Autograph Collection

ADERO Scottsdale Resort, Autograph Collection
2.2 mi from Mayo Clinic Scottsdale
United States
Garrett
£187
includes taxes & fees
18 Oct - 19 Oct
ADERO Scottsdale Resort, Autograph Collection
A modern hotel with a brick facade, large windows, and a covered entrance area.
A hotel room with a desk, two beds, a TV, and a large window.
A modern bar area with a wooden ceiling, bar stools, and a counter with a digital screen.
An outdoor patio area with round tables and chairs, a fire pit, and a large umbrella.

17. Springhill Suites Phoenix Scottsdale Marriott

Springhill Suites Phoenix Scottsdale Marriott
11.3 mi from Mayo Clinic Scottsdale
United States
Lucinda
£118
includes taxes & fees
25 Oct - 26 Oct
Springhill Suites Phoenix Scottsdale Marriott
A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.
A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.
A bar area with a bar counter, multiple chairs, and a sofa.
A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

18. Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
5.4 mi from Mayo Clinic Scottsdale
United States
PATRICK
£88
includes taxes & fees
26 Oct - 27 Oct
Aiden by Best Western Scottsdale North
A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.
An outdoor patio area with stone pillars, fire pit seating, and tables.
A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.
A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.

19. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard
Central Scottsdale, 7.6 mi from Mayo Clinic Scottsdale
United States
Dana
£131
includes taxes & fees
27 Oct - 28 Oct
Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard
A spacious lobby with stone walls, comfortable seating, and a large window offering a mountain view.
A spacious lobby with a central table set for a small gathering, flanked by seating and a modern ceiling design.
A spacious restaurant with wooden flooring, high tables, and chairs, featuring a bar area and large windows overlooking a scenic view.
A spacious living area with a large sectional sofa, wooden coffee tables, and a stone wall.

20. Hilton North Scottsdale At Cavasson

Hilton North Scottsdale At Cavasson
8.3 mi from Mayo Clinic Scottsdale
United States
Marcos
£223
includes taxes & fees
31 Oct - 1 Nov
Hilton North Scottsdale At Cavasson
View all properties

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

Talking Stick Resort

10/10 Excellent
"Amazing place, well maintained and clean. Only issue is that it's a drive to Old Town Scottsdale and and centers. But their Bellhop team and SUV's are available to run you anywhere in a 5 mile radius and are all amazingly friendly. And I believe the gym needs to be bigger with more equipment."
Jim 4-night trip
Posted less than an hour ago
Talking Stick Resort
Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent
"pleasant, good food idyllic setting"
Michael 2-night trip
Posted 6 hours ago
Sonesta Select Scottsdale at Mayo Clinic Campus
Inn at Eagle Mountain

Inn at Eagle Mountain

8/10 Good
"Clean room"
Shane 1-night trip
Posted 18 hours ago
Inn at Eagle Mountain
The Oasis Scottsdale - Bentley Award-Winning Resort Home

The Oasis Scottsdale - Bentley Award-Winning Resort Home

10/10 Excellent
"This is a fantastic vacation spot! The property is as amazing in-person as it is in the pictures and Kris is an excellent host. The courtyard/pool area gives major resort vibes but with the seclusion of a private rental. We definitely plan to be back!"
Geoff S. 5-night trip
Posted 2 days ago
The Oasis Scottsdale - Bentley Award-Winning Resort Home
Spectacular North Scottsdale desert home

Spectacular North Scottsdale desert home

10/10 Excellent
"This Scottsdale home is everything as advertised. Big and beautiful! Excellent for families and friends. I was there with 3 of my friends for a golf weekend and everything was perfect in the house. The house has everything you need. The bedrooms were big and roomy, bathrooms were clean. The kitchen had everything you needed such as appliances, pots and pans forks and spoons. All the accommodations of home.Thanks again, Andrew for sharing your home with us, we had a blast."
Rudolph J. 3-night trip
Posted 2 days ago
Spectacular North Scottsdale desert home
Grand Palms - Luxury Scottsdale Estate w/ Pool

Grand Palms - Luxury Scottsdale Estate w/ Pool

10/10 Excellent
"Our history Mitch was awesome. We loved the pool. We didn’t get to use the hot tub. Next time. Clean home. Needs some updating in the kitchen. So much room in the house. We spent most of our time out on the patio. Awesome. Would rent again."
Glory H. 3-night trip
Posted 3 days ago
Grand Palms - Luxury Scottsdale Estate w/ Pool
Scottsdale Paradise- POOL, Spa, Pickleball/Basketball, Fire Pit & Great HIKING!

Scottsdale Paradise- POOL, Spa, Pickleball/Basketball, Fire Pit & Great HIKING!

10/10 Excellent
"This home was perfect. Exactly as advertised. Perfect spot for our girls weekend with 8 adults. Loved the pickleball court, pool, comfortable seating areas inside and out."
Heather W. 3-night trip
Posted 4 days ago
Scottsdale Paradise- POOL, Spa, Pickleball/Basketball, Fire Pit & Great HIKING!
Luxury Single Story Home w/ Pool House, Heated Pool/Spa, Outdoor Living, Fire Pit, Garage Parking!

Luxury Single Story Home w/ Pool House, Heated Pool/Spa, Outdoor Living, Fire Pit, Garage Parking!

8/10 Good
"House was perfect for boys golf trip. Great house. Spacious and clean"
Ed C. 4-night trip
Posted 3 weeks ago
Luxury Single Story Home w/ Pool House, Heated Pool/Spa, Outdoor Living, Fire Pit, Garage Parking!
9 bd Luxury Oasis, Heated Pool and Spa, Pickle Ball!

9 bd Luxury Oasis, Heated Pool and Spa, Pickle Ball!

10/10 Excellent
"Overall our stay was great. The house is very large, perfect for a big group. It was very clean at check in. The beds were very comfortable. The pool area is fantastic. I think it was pretty great for a long weekend. About the only things I had any complaints about would be that the kitchen is pretty ill equipped to do any actual cooking in, and there should definitely be more plastic dishes and drink ware. We definitely didn’t want to be using glass or ceramic around the pool and on the patio, but we didn’t really have any options. It really was a great house and we would stay here again, we would just plan a little differently for meals."
SYDNEY M. 3-night trip
Posted 3 weeks ago
9 bd Luxury Oasis, Heated Pool and Spa, Pickle Ball!

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?
Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 22 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Mayo Clinic Scottsdale?
Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.
How many hotels will I find close to Mayo Clinic Scottsdale?
Expedia has 22 hotels and other accommodation options within a mile from Mayo Clinic Scottsdale.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to get the best deals available near Mayo Clinic Scottsdale.
What can I see and do near Mayo Clinic Scottsdale?
You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain or SunRidge Canyon Golf Club are some local sights worth checking out.