Title: The Best Hotels Closest to Marian Regional Medical Center in Santa Maria - 2026 Updated Prices | Expedia.co.uk [Santa Maria Travel Guide](https://expedia.co.uk/Santa-Maria.dx3224)[Holiday Rentals in Santa Maria](https://expedia.co.uk/Santa-Maria-Holiday-Rentals.d3224.Travel-Guide-HolidayRentals)[Flights to Santa Maria](https://expedia.co.uk/Cheap-Flights-To-Santa-Maria.d3224.Travel-Guide-Flights)[Things to do in Santa Maria](https://expedia.co.uk/Things-To-Do-In-Santa-Maria.d3224.Travel-Guide-Activities)[Marian Regional Medical Center Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Marian-Regional-Medical-Center.d553248621560560290.Car-Hire-Guide)[Marian Regional Medical Center Holidays](https://expedia.co.uk/Marian-Regional-Medical-Center-Santa-Maria.d553248621560560290.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [22 Mar - 23 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248621560560290&startDate=2026-03-22&endDate=2026-03-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [23 Mar - 24 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248621560560290&startDate=2026-03-23&endDate=2026-03-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248621560560290&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248621560560290&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Marian Regional Medical Center hotels ![2 Queen Designer | Premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/a4111cf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort ADA Suite - 112 | Living area | 50-inch Smart TV with cable channels, Netflix, streaming services](https://images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/8b75e1b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/a90fd08a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Designer | Premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/5b767704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Avanti [](https://www.expedia.co.uk/Santa-Maria-Hotels-Hotel-Avanti.h102791710.Hotel-Information) 1.6 mi from Marian Regional Medical Center 9.0/10 Wonderful (311 reviews) "Recommend this place forsure. Great location and very modern style rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adi £88 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Santa-Maria-Hotels-Hotel-Avanti.h102791710.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/373b886f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/0396337b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/272a77de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Santa Maria Inn [](https://www.expedia.co.uk/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) 1.5 mi from Marian Regional Medical Center 8.4/10 Very good (1,993 reviews) "Nice clean rooms, staff was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonia £70 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/fda3cb7d_edited_c5f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6:00 AM to 11:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/82a54fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking (Oversized Room;with Sofabed) | Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/ae1ae948.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/1170bb3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Big America [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Best-Western-Plus-Big-America.h15345.Hotel-Information) 1.9 mi from Marian Regional Medical Center 8.8/10 Excellent (1,002 reviews) "Pool was enjoyable and clean rooms. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rosie £100 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Best-Western-Plus-Big-America.h15345.Hotel-Information) ![Comfort Room | Desk, free WiFi](https://images.trvl-media.com/lodging/114000000/113750000/113740100/113740019/6a6be06e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/114000000/113750000/113740100/113740019/8da79328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | Desk, free WiFi](https://images.trvl-media.com/lodging/114000000/113750000/113740100/113740019/51470230.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | Bathroom | Soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/114000000/113750000/113740100/113740019/d675b652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Motel [](https://www.expedia.co.uk/Santa-Maria-Hotels-Villa-Motel.h113740019.Hotel-Information) 1.5 mi from Marian Regional Medical Center 8.0/10 Very good (231 reviews) "Good staff, good room service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Damien £52 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Santa-Maria-Hotels-Villa-Motel.h113740019.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/103000000/102600000/102593900/102593847/1d9b8fce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/103000000/102600000/102593900/102593847/1cd435c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, towels](https://images.trvl-media.com/lodging/103000000/102600000/102593900/102593847/5d8205ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/103000000/102600000/102593900/102593847/57a683d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ECONOMY INN [](https://www.expedia.co.uk/Santa-Maria-Hotels-ECONOMY-INN.h102593847.Hotel-Information) 1.5 mi from Marian Regional Medical Center 8.0/10 Very good (87 reviews) "Clean room lovely staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Salina £45 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Santa-Maria-Hotels-ECONOMY-INN.h102593847.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/790000/789200/789178/3533fa91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/1000000/790000/789200/789178/a9e9e3b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/790000/789200/789178/bf9fc606.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 9 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/790000/789200/789178/5eb76be7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santa Maria [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Travelodge-By-Wyndham-Santa-Maria.h789178.Hotel-Information) 1.8 mi from Marian Regional Medical Center 7.8/10 Good (1,002 reviews) "Good hotel, quiet and service also good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) vanda £80 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Travelodge-By-Wyndham-Santa-Maria.h789178.Hotel-Information) ![Standard Room, 2 Double Beds | Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/483bd489.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/bb2c1d01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/566069da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/0e007283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Santa Maria [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Days-Inn-By-Wyndham-Santa-Maria.h1088174.Hotel-Information) 0.6 mi from Marian Regional Medical Center 6.8/10 (1,000 reviews) "Room nice staff friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DARLENE £58 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Days-Inn-By-Wyndham-Santa-Maria.h1088174.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/42000/41946/8f653845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42000/41946/693dc8c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42000/41946/w2000h1120x0y0-aca4f3d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42000/41946/w2000h1325x0y0-3dfbaa9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Santa Maria, CA - South [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Motel-6-Santa-Maria.h41946.Hotel-Information) 0.5 mi from Marian Regional Medical Center 5.8/10 (524 reviews) "You get what you pay for " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leitu £74 includes taxes & fees 1 Apr - 2 Apr [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Motel-6-Santa-Maria.h41946.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/0d7c35a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Refrigerator | Bathroom | Combined shower/bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/46a3a6b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/d2f85309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/70982f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Santa Maria [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Santa-Maria.h38229980.Hotel-Information) 2.4 mi from Marian Regional Medical Center 9.4/10 Exceptional (1,002 reviews) "Very nice place to stay and staff were very respectful and nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina £98 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Santa-Maria.h38229980.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/718cc08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/330cc27f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed (Mobility & Hearing, Roll-In Shower) | Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/46fa7a48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/e01e83cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Santa Maria [](https://www.expedia.co.uk/Santa-Maria-Hotels-Homewood-Suites-By-Hilton-Santa-Maria.h12424.Hotel-Information) 2.3 mi from Marian Regional Medical Center 9.2/10 Wonderful (93 reviews) "Clean property, great staff and awesome breakfast! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pollavet £116 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/Santa-Maria-Hotels-Homewood-Suites-By-Hilton-Santa-Maria.h12424.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/f71ce1c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/e41940c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/be90ec77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/d553e532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santa Maria [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Fairfield-Inn-Suites-By-Marriott-Santa-Maria.h2733222.Hotel-Information) 2.2 mi from Marian Regional Medical Center 8.6/10 Excellent (761 reviews) "room was nice, staff friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randy £106 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Fairfield-Inn-Suites-By-Marriott-Santa-Maria.h2733222.Hotel-Information) ![Suite, 1 Bedroom (1 Queen Bed) | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/8c17c023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/127ce277.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/029aed65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/afc32ceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Santa Maria by IHG [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Candlewood-Suites-Santa-Maria.h2618252.Hotel-Information) 2.2 mi from Marian Regional Medical Center 8.6/10 Excellent (1,000 reviews) "It was surprisingly great and the 2 girls during check inn were very professional and accomadating thank you" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) lupe £78 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Candlewood-Suites-Santa-Maria.h2618252.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2040000/2039900/2039849/e08330df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2040000/2039900/2039849/638e2e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2040000/2039900/2039849/6c756f86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking | Premium bedding, pillow-top beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2040000/2039900/2039849/0fe189f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Solaire Inn & Suites [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Solaire-Inn-Suites.h2039849.Hotel-Information) 2.3 mi from Marian Regional Medical Center 8.2/10 Very good (1,002 reviews) "amazing place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eduardo £42 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Solaire-Inn-Suites.h2039849.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996400/996393/6644aec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/1000000/996400/996393/c7b43f50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996400/996393/97a8080c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/1000000/996400/996393/9fccf45d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Santa Maria, CA - North [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Motel-6-Santa-Maria.h996393.Hotel-Information) 2.3 mi from Marian Regional Medical Center 7.6/10 Good (1,154 reviews) "This place was great to stay for one two nights. Staff was super friendly! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Veronica £55 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Motel-6-Santa-Maria.h996393.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/c2079151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/2344a3d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/10bd6760.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/caf8168a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wine Stone Inn [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Wine-Stone-Inn.h39514495.Hotel-Information) 6.3 mi from Marian Regional Medical Center 9.8/10 Exceptional (622 reviews) "The hotel was very nice, and the staff helpful. The bar was a fun place to be in the evening. We had a wonderful time. ." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judy £152 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Wine-Stone-Inn.h39514495.Hotel-Information) ![Standard Room, 1 King Bed | Desk, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/17000000/16160000/16153000/16152993/e6af4c57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/17000000/16160000/16153000/16152993/780dd7c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Desk, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/17000000/16160000/16153000/16152993/db2f7b23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16160000/16153000/16152993/2ed324bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Colonial Motel [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Colonial-Motel.h16152993.Hotel-Information) 2.1 mi from Marian Regional Medical Center 6.4/10 (192 reviews) "Clean rooms, smaller well kept motel in a good location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darren £84 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Colonial-Motel.h16152993.Hotel-Information) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/598df5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/33b4a0e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/4ed108b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/2c732443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Santa Maria [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Radisson-Hotel-Santa-Maria.h433636.Hotel-Information) 4.2 mi from Marian Regional Medical Center 7.4/10 Good (1,330 reviews) "Clean room staff was really nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Veronica £85 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Radisson-Hotel-Santa-Maria.h433636.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5180000/5175700/5175661/1d731cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5180000/5175700/5175661/625f8ab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Chapter 3 | Individually decorated, individually furnished, iron/ironing board](https://images.trvl-media.com/lodging/6000000/5180000/5175700/5175661/85b5e3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/6000000/5180000/5175700/5175661/2cb34bf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kaleidoscope Inn & Gardens [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Kaleidoscope-Inn-Gardens.h5175661.Hotel-Information) 7.3 mi from Marian Regional Medical Center 8.4/10 Very good (208 reviews) "The place was charming and the room very comfortable and spacious. It had everything you need. The only complaint I would have is that because it is an old Victorian, every window and door is loos and there is no insulation whatsoever. That means that you can hear every sound from every room and even with a breeze the windows and doors rattle all night. I guess that's what old Victorians are like." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina £114 includes taxes & fees 24 Mar - 25 Mar [](https://www.expedia.co.uk/San-Luis-Obispo-Hotels-Kaleidoscope-Inn-Gardens.h5175661.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-05&endDate=2026-04-06®ionId=553248621560560290&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Marian Regional Medical Center | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![2 Queen Designer \| Premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/a4111cf9.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Avanti | 2.5 star property | 9.0Wonderful311 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/373b886f.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Historic Santa Maria Inn | 3.5 star property | 8.4Very good1,993 reviews | View | | | | | | | ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/fda3cb7d_edited_c5f0.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Best Western Plus Big America | 2.5 star property | 8.8Excellent1,002 reviews | View | | | | | | | ![Comfort Room \| Desk, free WiFi](https://images.trvl-media.com/lodging/114000000/113750000/113740100/113740019/6a6be06e.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Villa Motel | 2.0 star property | 8.0Very good231 reviews | View | | | | | | | ![Reception](https://images.trvl-media.com/lodging/103000000/102600000/102593900/102593847/1d9b8fce.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)ECONOMY INN | 2.5 star property | 8.0Very good87 reviews | View | | | | | | ## Top Marian Regional Medical Center Hotel Reviews ![Historic Santa Maria Inn](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/373b886f_y.jpg) ### Historic Santa Maria Inn 10/10 Excellent "Wish there were towel bars/ racks in the bathroom. As I am disabled, the toilet paper is in an awkward location. However, my stay was great and it is highly likely that I will stay there again. " [](https://expedia.co.uk/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Villa Motel](https://images.trvl-media.com/lodging/114000000/113750000/113740100/113740019/6a6be06e_y.jpg) ### Villa Motel 6/10 Okay "Nice enough for an inexpensive stop over. The room didn’t have coffee for those who might need it in the morning, but did have a small fridge and microwave. It also needed black out curtains, as the lighted court yard shone right through the curtains all night. " [](https://expedia.co.uk/Santa-Maria-Hotels-Villa-Motel.h113740019.Hotel-Information) ![Edgewater Inn And Suites](https://images.trvl-media.com/lodging/1000000/900000/894000/893902/3beb869e_y.jpg) ### Edgewater Inn And Suites 6/10 Okay "Very welcoming for our pet staff and everyone so friendly " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Edgewater-Inn-And-Suites.h893902.Hotel-Information) ![SeaCrest OceanFront Hotel](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/b40c24d9_y.jpg) ### SeaCrest OceanFront Hotel 10/10 Excellent "There is a variety of places to sit, visit, watch the waves, or dine. It is very convenient to have breakfast on site. Overall, it exceeded my expectations." [](https://expedia.co.uk/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ![Hotel Avanti](https://images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/a4111cf9_y.jpg) ### Hotel Avanti 6/10 Okay "Staff was nice and rooms were obviously renovated, but I did have a cockroach greet me upon arrival. The hotel itself sits on a ver busy road that is popular for “ cruising “ to drag racing. So it was kind of loud." [](https://expedia.co.uk/Santa-Maria-Hotels-Hotel-Avanti.h102791710.Hotel-Information) ![Sandcastle Hotel on the Beach](https://images.trvl-media.com/lodging/1000000/50000/41000/40915/99213fd0_y.jpg) ### Sandcastle Hotel on the Beach 10/10 Excellent "Great hotel! We were there for only one night. Loved that they had kids toys and chairs to borrow for the beach. We will be staying there again for sure! " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Sandcastle-Hotel-On-The-Beach.h40915.Hotel-Information) ![Oxford Suites Pismo Beach](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/010bbafb_y.jpg) ### Oxford Suites Pismo Beach 10/10 Excellent "We enjoyed our stay. It was clean and comfortable. Very easy access right off of the freeway. There is a social our in which they offer some light snacks and adult guests recieve a ticket for a cocktail or a glass of wine or a beer. They have a nice breakfast as well. " [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![The Agrarian Hotel, BW Signature Collection](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/dea8ddbe_y.jpg) ### The Agrarian Hotel, BW Signature Collection 10/10 Excellent "My wife and I stay at this hotel every time we visit the central coast. It’s very clean and comfortable and a delicious breakfast to top it off. The value is definitely there. We love staying here, I think you will too." [](https://expedia.co.uk/San-Luis-Obispo-Hotels-The-Agrarian-Hotel.h36117545.Hotel-Information) ![Homewood Suites by Hilton Santa Maria](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3836h2557x4y3-ba31f59e_y.jpg) ### Homewood Suites by Hilton Santa Maria 10/10 Excellent "Nice hotel. Loved the complementary breakfast " [](https://expedia.co.uk/Santa-Maria-Hotels-Homewood-Suites-By-Hilton-Santa-Maria.h12424.Hotel-Information) ## Hotels near other Marian Regional Medical Center attractions ### Pacific Conservatory Theatre You can enjoy a show at Pacific Conservatory Theatre on your trip to Santa Maria. While in this romantic area, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6209504) ### Simas Park After visiting Simas Park, make a plan to see the other sights and activities in Santa Maria. While in this romantic area, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6200043) ### Natural History Museum 3.8/5 (52 reviews) You can spend an afternoon studying the exhibits at Natural History Museum in Santa Maria. While in this romantic area, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6209508) ### Regal Edwards Santa Maria & RPX You can take time to visit Regal Edwards Santa Maria & RPX during your travels to Santa Maria. Visit the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941654002322817024) ### Santa Maria Valley Discovery Museum 5.0/5 (2 reviews) You can take time to visit Santa Maria Valley Discovery Museum during your travels to Santa Maria. While in this romantic area, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6200056) ### Santa Maria Valley Historical Society 4.0/5 (1 review) You can spend time browsing the exhibits at Santa Maria Valley Historical Society in Santa Maria. While in this family-friendly area, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561135488) ### Santa Maria Civic Theatre You can enjoy a show at Santa Maria Civic Theatre during your trip to Santa Maria. While in this romantic area, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621556207167) ### Santa Maria Fairpark 4.1/5 (36 reviews) Take the family on an outing to Santa Maria Fairpark during your trip to Santa Maria. While in this romantic area, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558560619) ## Frequently asked questions ### What's the area like around Marian Regional Medical Center? ### Where is the best place to stay close to Marian Regional Medical Center? ### How many hotels will I be able to find near Marian Regional Medical Center? ### If I need to cancel the hotel reservation for my stay near Marian Regional Medical Center, will I receive a refund? ### What can I see and do near Marian Regional Medical Center?