Find hotels in Lupus, MO from £35

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Lupus hotels

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO
2.5 star property
Columbia
8.2 out of 10, Very good, (673 reviews)
"Friendly staff, hot Continental breakfast, clean rooms. Definitely one of the nicer baymonts we've booked into. "
Canada
Tracy
The price is £50
includes taxes & fees
4 Mar - 5 Mar
Baymont by Wyndham Columbia, MO

Best Western Plus Columbia Inn

Best Western Plus Columbia Inn
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,245 reviews)
"Very clean, smelled fresh, staff friendly!"
United States
Darci
The price is £61
includes taxes & fees
1 Mar - 2 Mar
Best Western Plus Columbia Inn

Ramada by Wyndham Columbia

Ramada by Wyndham Columbia
2.5 star property
Columbia
7.6 out of 10, Good, (1,001 reviews)
"Great, will be back next week"
United States
Matthew
The price is £54
includes taxes & fees
8 Mar - 9 Mar
Ramada by Wyndham Columbia

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,002 reviews)
"Great breakfast, great stay!!"
United States
Rebecca
The price is £86
includes taxes & fees
23 Mar - 24 Mar
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,747 reviews)
"Room, staff and breakfast were wonderful."
United States
Marvin
The price is £73
includes taxes & fees
22 Mar - 23 Mar
Country Inn & Suites by Radisson, Columbia, MO

Drury Inn & Suites Columbia Stadium Boulevard

Drury Inn & Suites Columbia Stadium Boulevard
3.0 star property
Columbia
9.4 out of 10, Exceptional, (1,001 reviews)
"Excellent service and stay!"
United States
David
The price is £83
includes taxes & fees
8 Mar - 9 Mar
Drury Inn & Suites Columbia Stadium Boulevard

Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia
3.0 star property
Columbia
9.0 out of 10, Wonderful, (1,249 reviews)
"Rooms were very clean & comfortable! "
United States
stefanie
The price is £68
includes taxes & fees
8 Mar - 9 Mar
Wingate by Wyndham - Columbia

Days Inn by Wyndham Boonville

Days Inn by Wyndham Boonville
2.0 star property
Boonville
6.0 out of 10, (1,000 reviews)
"Quick and easy checkin, bed was great. "
United States
Darwyn
The price is £35
includes taxes & fees
1 Mar - 2 Mar
Days Inn by Wyndham Boonville

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
3.0 star property
Boonville
8.4 out of 10, Very good, (969 reviews)
"Always a good time and exceptional hotel"
United States
Nancy
The price is £73
includes taxes & fees
4 Mar - 5 Mar
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Wyndham Executive Center Columbia

Wyndham Executive Center Columbia
3.5 star property
Columbia
8.2 out of 10, Very good, (1,000 reviews)
"Clean great staff. They have a bar!!"
United States
Tom
The price is £94
includes taxes & fees
1 Mar - 2 Mar
Wyndham Executive Center Columbia

Tru By Hilton Columbia South

Tru By Hilton Columbia South
2.5 star property
Columbia
8.8 out of 10, Excellent, (6 reviews)
"Room was great! Clean and friendly staff"
United States
Tara
The price is £87
includes taxes & fees
22 Mar - 23 Mar
Tru By Hilton Columbia South

Super 8 by Wyndham Columbia East

Super 8 by Wyndham Columbia East
2.0 star property
Columbia
6.2 out of 10, (1,002 reviews)
"Very clean hotel with friendly and helpful staff "
United States
Deborah
The price is £49
includes taxes & fees
8 Mar - 9 Mar
Super 8 by Wyndham Columbia East

Hilton Garden Inn Columbia

Hilton Garden Inn Columbia
3.0 star property
Columbia
8.6 out of 10, Excellent, (529 reviews)
"Very good! "
United States
Solomon
The price is £102
includes taxes & fees
29 Mar - 30 Mar
Hilton Garden Inn Columbia

Holiday Inn Columbia East by IHG

Holiday Inn Columbia East by IHG
3.0 star property
Columbia
8.4 out of 10, Very good, (1,002 reviews)
"Buffet breakfast was a great option and the staff working it were awesome! "
United States
Matthew
The price is £87
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Columbia East by IHG

Quality Inn & Suites Columbia I-70

Quality Inn & Suites Columbia I-70
2.5 star property
Columbia
7.0 out of 10, Good, (836 reviews)
"Clean rooms and excellent service"
United States
Sarah
The price is £52
includes taxes & fees
3 Mar - 4 Mar
Quality Inn & Suites Columbia I-70

Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East
3.0 star property
Columbia
9.6 out of 10, Exceptional, (1,382 reviews)
"Great stay, very clean and very nice!"
United States
Joshua
The price is £82
includes taxes & fees
22 Mar - 23 Mar
Drury Plaza Hotel Columbia East

Quality Inn & Suites Boonville - Columbia

Quality Inn & Suites Boonville - Columbia
2.5 star property
Boonville
7.4 out of 10, Good, (588 reviews)
"The room was clean, staff was super friendly, and the pool and hot tub were excellent"
United States
Kelsey
The price is £77
includes taxes & fees
3 Mar - 4 Mar
Quality Inn & Suites Boonville - Columbia

Hampton Inn Columbia

Hampton Inn Columbia
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,000 reviews)
"Everything was top notch from the room to the great breakfast. Convenient to find, easy parking close to room. Manager and staff very nice and helpful! I will definitely stay here again if in the area. "
United States
Teresa
The price is £88
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn Columbia

Comfort Suites Columbia - University Area

Comfort Suites Columbia - University Area
2.5 star property
Columbia
7.8 out of 10, Good, (967 reviews)
"The staff was great, the room was quiet, ckean and in good repair (looked very new)."
United States
Marsha
The price is £79
includes taxes & fees
1 Mar - 2 Mar
Comfort Suites Columbia - University Area

Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia
2.5 star property
Columbia
8.6 out of 10, Excellent, (1,367 reviews)
"I love the beds they are so comfortable it’s like sleeping on clouds ☁️ "
United States
Jennifer
Stoney Creek Hotel Columbia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Holiday Sale

Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Lupus attractions

Top Lupus Hotel Reviews

More cheap stays in Lupus

Frequently asked questions

When is the best time to go to Lupus?
The best time to visit Lupus, Missouri, is during the spring (April to May) and autumn (September to October) months.

These seasons offer pleasant weather, with mild temperatures and lower humidity, making outdoor activities and exploring the scenic Missouri River bluffs more enjoyable. Spring brings blooming wildflowers, while autumn showcases beautiful fall foliage, adding to the area's natural beauty.

For those looking to participate in local agricultural events or enjoy the outdoors without the intense summer heat, these periods are ideal.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lupus.
How can I save on a Lupus hotel booking with Expedia?
Members always get our best prices. Find our best Lupus hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Lupus hotel?
Prices for hotels in Lupus often vary, but you can find a great deal from £35 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia