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Check prices for these dates

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

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Our top choices for Lexington Medical Center hotels

An outdoor patio with a brick barbecue, wicker furniture, and string lights.

1. Residence Inn Columbia West/Lexington

Residence Inn Columbia West/Lexington
3.0 star property
0.3 mi from Lexington Medical Center
9.2 out of 10, Wonderful, (430 reviews)
"The check in was a bit slow but the property was excellent. The room was great and the breakfast was excellent."
United States
Bruce E
The price is £95
includes taxes & fees
1 Dec - 2 Dec
Residence Inn Columbia West/Lexington
An outdoor patio with wicker furniture, a central fire pit, and red umbrellas.

2. TownePlace Suites Columbia West/Lexington

TownePlace Suites Columbia West/Lexington
3.0 star property
0.3 mi from Lexington Medical Center
9.2 out of 10, Wonderful, (510 reviews)
"We stay at this location often and enjoy proximity to convenient eating options, friendly staff and comfortable rooms. Free breakfast is a plus."
United States
Michael
The price is £96
includes taxes & fees
23 Nov - 24 Nov
TownePlace Suites Columbia West/Lexington
A patio area with wicker furniture, a central fire pit, and outdoor umbrellas.

3. Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport
3.0 star property
0.3 mi from Lexington Medical Center
9.0 out of 10, Wonderful, (1,003 reviews)
"The staff was so friendly and helpful. The food at the restaurant on site was delicious!! The room was clean and bed was comfortable."
United States
SHERI
The price is £82
includes taxes & fees
26 Nov - 27 Nov
Hilton Garden Inn Columbia Airport
A modern building entrance with a brick pathway leading to a glass door.

4. Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport
2.5 star property
0.4 mi from Lexington Medical Center
8.2 out of 10, Very good, (1,001 reviews)
"Great place to stay!"
United States
Vicky
The price is £76
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn Columbia-I-26 Airport
A hotel lobby with a brown sofa, a small table, a refrigerator stocked with snacks, a staircase with a green wall, and a dining area in the background.

5. Sleep Inn Columbia

Sleep Inn Columbia
2.5 star property
1.7 mi from Lexington Medical Center
8.2 out of 10, Very good, (1,223 reviews)
"It was a great stay for me and the family would stay again!"
United States
Emily
The price is £61
includes taxes & fees
26 Nov - 27 Nov
Sleep Inn Columbia
A spacious lobby with a high ceiling, a staircase, a large sofa, a coffee table, and a TV mounted on the wall.

6. Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC
4.0 star property
1.9 mi from Lexington Medical Center
8.0 out of 10, Very good, (1,004 reviews)
"Beds were amazing staff was very friendly and accommodating"
United States
Donna
The price is £74
includes taxes & fees
15 Nov - 16 Nov
Doubletree by Hilton Columbia, SC
A hotel room with a sofa, a small table, a bed, and a painting on the wall.

7. Best Western Executive Inn & Suites

Best Western Executive Inn & Suites
2.5 star property
1.6 mi from Lexington Medical Center
8.0 out of 10, Very good, (745 reviews)
"Nice"
United States
Toyia
The price is £97
includes taxes & fees
3 Nov - 4 Nov
Best Western Executive Inn & Suites
A hotel reception desk with a 'Comfort Inn' sign, a digital screen, and a 'Welcome' mat.

8. Comfort Inn Columbia West

Comfort Inn Columbia West
2.5 star property
1.8 mi from Lexington Medical Center
7.4 out of 10, Good, (1,000 reviews)
"Decent stay for the price. Breakfast is good."
United States
Cornelius
The price is £64
includes taxes & fees
26 Nov - 27 Nov
Comfort Inn Columbia West
A reception area with a stone mosaic wall, a wooden reception desk, and a counter with a green top. There are framed certificates on the wall and a vending machine to the right.

9. Quality Inn Columbia Airport

Quality Inn Columbia Airport
2.5 star property
1.7 mi from Lexington Medical Center
6.8 out of 10, (1,002 reviews)
"i really enjoyed my stay very cleaned and maintained with very helpful staff!"
United States
Jmesha
The price is £51
includes taxes & fees
1 Dec - 2 Dec
Quality Inn Columbia Airport
A living room with a sofa, chairs, a coffee table, a TV, and a radiator.

10. Knights Inn Columbia

Knights Inn Columbia
1.5 star property
1.6 mi from Lexington Medical Center
6.4 out of 10, (558 reviews)
"Help with checking in"
United States
Raheeam
The price is £65
includes taxes & fees
3 Nov - 4 Nov
Knights Inn Columbia
A bar area with wooden chairs, a counter with a computer, and a seating area with a sofa and chairs.

11. Clarion Inn Columbia Airport

Clarion Inn Columbia Airport
2.5 star property
1.7 mi from Lexington Medical Center
6.0 out of 10, (1,001 reviews)
"Do not stay there I repeat, Expedia will not give you your money back!!!!!!!!"
United States
Sheneke
The price is £42
includes taxes & fees
9 Nov - 10 Nov
Clarion Inn Columbia Airport
A hotel room with two beds, a desk with a computer, a chair, and a view of the outdoors.

12. Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest
2.5 star property
1.8 mi from Lexington Medical Center
5.6 out of 10, (1,002 reviews)
"The rooms were dirty. We had our room changed 3 times due to it was dirty. The room had roaches end up getting my money back. My elderly mother and I had to find another hotel somewhere to sleep 11 pm at night ."
United States
Latoya
The price is £57
includes taxes & fees
8 Nov - 9 Nov
Baymont by Wyndham Columbia Northwest
A modern living room with a grey sofa, a coffee table, and a dining area with a table and chairs.

13. Columbia Duet Unit B

Columbia Duet Unit B
2.0 star property
1.8 mi from Lexington Medical Center
The price is £638
includes taxes & fees
9 Nov - 10 Nov
Columbia Duet Unit B
A dining area with a wooden table, chairs, and a lamp. There is a plant on a shelf and a TV mounted on the wall.

14. Columbia Duet - 2 Units

Columbia Duet - 2 Units
3.0 star property
1.8 mi from Lexington Medical Center
The price is £1,085
includes taxes & fees
9 Nov - 10 Nov
Columbia Duet - 2 Units
A spacious indoor area with a long table, multiple chairs, and a seating area with sofas and a TV.

15. The Lantern Hotel Columbia

The Lantern Hotel Columbia
4.0 star property
4.5 mi from Lexington Medical Center
9.8 out of 10, Exceptional, (228 reviews)
"Location for us was perfect. The staff were friendly and very helpful. The hotel was very nice."
United States
Nichole
The price is £117
includes taxes & fees
29 Nov - 30 Nov
The Lantern Hotel Columbia
A modern living room with a blue cabinet, a blue sofa, a round coffee table, and patterned ottomans.

16. Hotel Trundle

Hotel Trundle
3.0 star property
4.5 mi from Lexington Medical Center
9.8 out of 10, Exceptional, (1,004 reviews)
"Great spot to stay."
United States
Nicolas
The price is £140
includes taxes & fees
2 Dec - 3 Dec
Hotel Trundle
A modern hotel lobby with a large dining table, multiple seating areas, and a large screen wall.

17. Hampton Inn & Suites Lexington Columbia

Hampton Inn & Suites Lexington Columbia
2.5 star property
3.4 mi from Lexington Medical Center
9.6 out of 10, Exceptional, (713 reviews)
"Very pleasant stay. Great staff."
United States
Jean
The price is £88
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites Lexington Columbia
An outdoor patio with a stone fire pit, seating, and a covered area with lights.

18. Springhill Suites by Marriott Columbia near Fort Jackson

Springhill Suites by Marriott Columbia near Fort Jackson
2.0 star property
9.6 mi from Lexington Medical Center
9.4 out of 10, Exceptional, (862 reviews)
"I loved my stay!"
United States
Leslie
The price is £91
includes taxes & fees
22 Nov - 23 Nov
Springhill Suites by Marriott Columbia near Fort Jackson
A modern hotel room with a large bed, a seating area, and a TV.

19. Homewood Suites By Hilton Columbia Downtown

Homewood Suites By Hilton Columbia Downtown
3.0 star property
3.9 mi from Lexington Medical Center
9.6 out of 10, Exceptional, (166 reviews)
"Great Place to stay"
United States
Brian
The price is £106
includes taxes & fees
15 Nov - 16 Nov
Homewood Suites By Hilton Columbia Downtown
A modern bar area with a long counter, multiple bar stools, and a decorative wall with geometric patterns.

20. Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown
2.5 star property
3.9 mi from Lexington Medical Center
9.4 out of 10, Exceptional, (972 reviews)
"Great stay"
United States
Jennifer
The price is £82
includes taxes & fees
15 Nov - 16 Nov
Tru By Hilton Columbia Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Lexington Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
An outdoor patio with a brick barbecue, wicker furniture, and string lights.
Residence Inn Columbia West/Lexington
3.0 star property
9.2
Wonderful
430 reviews
View
An outdoor patio with wicker furniture, a central fire pit, and red umbrellas.
TownePlace Suites Columbia West/Lexington
3.0 star property
9.2
Wonderful
510 reviews
View
A patio area with wicker furniture, a central fire pit, and outdoor umbrellas.
Hilton Garden Inn Columbia Airport
3.0 star property
9.0
Wonderful
1,003 reviews
View
A modern building entrance with a brick pathway leading to a glass door.
Hampton Inn Columbia-I-26 Airport
2.5 star property
8.2
Very good
1,001 reviews
View
A hotel lobby with a brown sofa, a small table, a refrigerator stocked with snacks, a staircase with a green wall, and a dining area in the background.
Sleep Inn Columbia
2.5 star property
8.2
Very good
1,223 reviews
View

Top Lexington Medical Center Hotel Reviews

Tru By Hilton Columbia Greystone

Tru By Hilton Columbia Greystone

10/10 Excellent
"This is the 2nd time I booked this hotel in 2 weeks because I loved it so much! Staff is so friendly! Rooms are super clean. Very reasonable price! Breakfast is a nice touch! The river walk is a 3 min drive and it’s awesome! Highly recommend!"
Kellie 1-night trip
Posted 15 hours ago
Tru By Hilton Columbia Greystone

Frequently asked questions

What's the area like around Lexington Medical Center?
Lexington Medical Center is located in West Columbia. Travellers like the surrounding area for its bars. If you're looking for a convenient place to stay, take a look at the 15 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Lexington Medical Center?
Adjacent to Lexington Medical Center, Hilton Garden Inn Columbia Airport is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and free parking. Other good choices within a short distance include Hampton Inn Columbia-I-26 Airport and Residence Inn Columbia West/Lexington.
How many hotels are there near Lexington Medical Center?
Expedia has 15 hotels and other accommodation options within a mile from Lexington Medical Center.
If I need to cancel the hotel reservation for my stay near Lexington Medical Center, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the best options available near Lexington Medical Center.
What can I see and do near Lexington Medical Center?
Study the collections at South Carolina State Museum, Columbia Museum of Art or Robert Mills Historic House and Park. While you're exploring, swing by First Baptist Church, South Carolina State House and Imara Woman to learn a bit about the area. You can check out the local talent at Koger Center for the Arts, Township Auditorium and Town Theatre.