Title: The Best Hotels Closest to Lexington Medical Center in West Columbia - 2026 Updated Prices | Expedia.co.uk [Holiday Rentals in West Columbia](https://expedia.co.uk/West-Columbia-Holiday-Rentals.d7693.Travel-Guide-HolidayRentals)[Flights to West Columbia](https://expedia.co.uk/Cheap-Flights-To-West-Columbia.d7693.Travel-Guide-Flights)[Lexington Medical Center Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Lexington-Medical-Center.d624549612579786752.Car-Hire-Guide)[Lexington Medical Center Holidays](https://expedia.co.uk/Lexington-Medical-Center-West-Columbia.d624549612579786752.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [8 Feb - 9 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624549612579786752&startDate=2026-02-08&endDate=2026-02-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [9 Feb - 10 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624549612579786752&startDate=2026-02-09&endDate=2026-02-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624549612579786752&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624549612579786752&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Lexington Medical Center hotels ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/19000000/18230000/18228600/18228549/2dd545dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed | Living area | 40-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/19000000/18230000/18228600/18228549/w3994h2654x6y8-55e40291.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/19000000/18230000/18228600/18228549/ad21eb76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/19000000/18230000/18228600/18228549/739d2844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Columbia West/Lexington [](https://www.expedia.co.uk/Columbia-Hotels-Residence-Inn-Columbia-WestLexington.h18228549.Hotel-Information) 0.3 mi from Lexington Medical Center 9.2/10 Wonderful (364 reviews) "The staff was very accommodating." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wanda £108 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Residence-Inn-Columbia-WestLexington.h18228549.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3200000/3191900/3191843/8abca080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3200000/3191900/3191843/d933487d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3200000/3191900/3191843/8c7f0988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3200000/3191900/3191843/e3b96f81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Columbia Airport [](https://www.expedia.co.uk/Columbia-Hotels-Hilton-Garden-Inn-Columbia-Airport.h3191843.Hotel-Information) 0.3 mi from Lexington Medical Center 9.0/10 Wonderful (1,001 reviews) "Good amenities, nice room, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas £98 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Hilton-Garden-Inn-Columbia-Airport.h3191843.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/60000000/59790000/59784600/59784598/588e3575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds | 1 bedroom, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/60000000/59790000/59784600/59784598/9b6acf78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/60000000/59790000/59784600/59784598/74db0cbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/60000000/59790000/59784600/59784598/efefafd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites Columbia West/Lexington [](https://www.expedia.co.uk/Columbia-Hotels-TownePlace-Suites-Columbia-WestLexington.h59784598.Hotel-Information) 0.3 mi from Lexington Medical Center 9.2/10 Wonderful (460 reviews) "Great place easy check in easy check out close to everything " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Quinton £102 includes taxes & fees 26 Feb - 27 Feb [](https://www.expedia.co.uk/Columbia-Hotels-TownePlace-Suites-Columbia-WestLexington.h59784598.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/7600/7503/0f42dc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/7600/7503/013897f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/7600/7503/b495eb66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking | Premium bedding, in-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/7600/7503/84f0bcb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Columbia-I-26 Airport [](https://www.expedia.co.uk/Columbia-Hotels-Hampton-Inn-Columbia-I-26-Airport.h7503.Hotel-Information) 0.4 mi from Lexington Medical Center 8.2/10 Very good (1,007 reviews) "The staff was friendly and accommodating! I also loved the complimentary breakfast offered as well as the other food options in the area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamari £75 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Hampton-Inn-Columbia-I-26-Airport.h7503.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/de238acf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/f8fb6cdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/736eada4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/07f6de7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Columbia [](https://www.expedia.co.uk/Columbia-Hotels-Sleep-Inn-At-Bush-River-Road.h126908.Hotel-Information) 1.7 mi from Lexington Medical Center 8.2/10 Very good (1,009 reviews) "Super clean, new carpet, excellent staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marc £67 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Columbia-Hotels-Sleep-Inn-At-Bush-River-Road.h126908.Hotel-Information) ![Suite, 1 King Bed, Non Smoking, Microwave | Pillow-top beds, desk, laptop workspace, WiFi](https://images.trvl-media.com/lodging/1000000/80000/77800/77728/caa478e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/77800/77728/acf0b5f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/80000/77800/77728/12041de1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/80000/77800/77728/338c688c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Executive Inn & Suites [](https://www.expedia.co.uk/Columbia-Hotels-Best-Western-Executive-Inn-Suites.h77728.Hotel-Information) 1.6 mi from Lexington Medical Center 8.0/10 Very good (720 reviews) "The staff was awesome!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayla £87 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Best-Western-Executive-Inn-Suites.h77728.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1100/1090/77a41033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/1100/1090/db46c2f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Balcony (Hearing, Top Floor) | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/1100/1090/b9e38acd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed with Sofa bed | Executive lounge](https://images.trvl-media.com/lodging/1000000/10000/1100/1090/800ef8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Columbia, SC [](https://www.expedia.co.uk/Columbia-Hotels-Doubletree-By-Hilton-Columbia.h1090.Hotel-Information) 1.9 mi from Lexington Medical Center 8.0/10 Very good (1,002 reviews) "Great location, very clean and well kept hotel. Would definitely go again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy £99 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Doubletree-By-Hilton-Columbia.h1090.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43600/43552/85f969b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43600/43552/adc43e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/43600/43552/2d2752e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43600/43552/46138146.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Columbia West [](https://www.expedia.co.uk/Columbia-Hotels-Comfort-Inn-Columbia-Bush-River.h43552.Hotel-Information) 1.8 mi from Lexington Medical Center 7.4/10 Good (1,001 reviews) "Staff was great. Hot breakfast was really good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caprice £58 includes taxes & fees 7 Mar - 8 Mar [](https://www.expedia.co.uk/Columbia-Hotels-Comfort-Inn-Columbia-Bush-River.h43552.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/124300/124257/74c6421c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/130000/124300/124257/db1a489c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/124300/124257/9da4cd64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/124300/124257/251c9c15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Columbia Airport [](https://www.expedia.co.uk/Columbia-Hotels-Quality-Inn.h124257.Hotel-Information) 1.7 mi from Lexington Medical Center 6.8/10 (1,000 reviews) "Friendly staff, good parking, comfortable bed & pillows." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen £50 includes taxes & fees 9 Mar - 10 Mar [](https://www.expedia.co.uk/Columbia-Hotels-Quality-Inn.h124257.Hotel-Information) ![Iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/16000000/15880000/15875600/15875546/3c60d9bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/16000000/15880000/15875600/15875546/fd6032dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/16000000/15880000/15875600/15875546/932c186e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/16000000/15880000/15875600/15875546/4f4aa557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Executive Inn [](https://www.expedia.co.uk/Columbia-Hotels-Executive-Inn.h15875546.Hotel-Information) 0.3 mi from Lexington Medical Center 6.8/10 (152 reviews) "Great location and place to stay while traveling. Older motel but very clean and beds comfortable. Owners very nice. 2nd time staying here. Will stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) coleen £51 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Executive-Inn.h15875546.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/123500/123410/c718d8ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/123500/123410/5e96d4e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/130000/123500/123410/83a1e761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/123500/123410/0504185e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Knights Inn Columbia [](https://www.expedia.co.uk/Columbia-Hotels-Knights-Inn-Columbia.h123410.Hotel-Information) 1.6 mi from Lexington Medical Center 6.4/10 (550 reviews) "For an older property, it was clean, comfortable and affordable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kearney £52 includes taxes & fees 13 Feb - 14 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Knights-Inn-Columbia.h123410.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/22500/22476/5d6e07d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/22500/22476/bad2b208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/22500/22476/f2bdc05a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22476/ea2c5e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarion Inn Columbia Airport [](https://www.expedia.co.uk/Columbia-Hotels-Clarion-Inn-Airport.h22476.Hotel-Information) 1.7 mi from Lexington Medical Center 6.0/10 (1,001 reviews) "Room needed painting and updating. Bed was clean, towels and bathroom were fine. TV was just sitting without a stand leaning against the wall. I’m a low maintenance traveler, it met my needs for the night. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) eric £41 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Columbia-Hotels-Clarion-Inn-Airport.h22476.Hotel-Information) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/17600/17541/5be6ae86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/17600/17541/34ad55ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast on weekdays ](https://images.trvl-media.com/lodging/1000000/20000/17600/17541/03762d6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17600/17541/dadb43c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Columbia Northwest [](https://www.expedia.co.uk/Columbia-Hotels-Baymont-By-Wyndham-Columbia-Northwest.h17541.Hotel-Information) 1.8 mi from Lexington Medical Center 5.4/10 (1,002 reviews) "Friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph £42 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Baymont-By-Wyndham-Columbia-Northwest.h17541.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/532100/532027/5f39b433.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/540000/532100/532027/be440b3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/532100/532027/795b3938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/540000/532100/532027/6959b215.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Columbia [](https://www.expedia.co.uk/Columbia-Hotels-Days-Inn-By-Wyndham-Columbia.h532027.Hotel-Information) 1.7 mi from Lexington Medical Center 4.2/10 (1,002 reviews) "The sink clogged during the second day." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawn £41 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Days-Inn-By-Wyndham-Columbia.h532027.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/110000000/109030000/109029100/109029091/0e6a5b41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![12 bedrooms, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109030000/109029100/109029091/f5378ebe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/110000000/109030000/109029100/109029091/61459727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/110000000/109030000/109029100/109029091/e1e71064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Columbia Duet - 2 Units [](https://www.expedia.co.uk/West-Columbia-Hotels-Columbia-Duet-2-Units.h109029091.Hotel-Information) 1.8 mi from Lexington Medical Center £1,097 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/West-Columbia-Hotels-Columbia-Duet-2-Units.h109029091.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/110000000/109300000/109292600/109292506/c5f84c6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109300000/109292600/109292506/w1042h691x1y0-7d326b38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109300000/109292600/109292506/w1042h694x2y0-c213701d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/110000000/109300000/109292600/109292506/w1042h695x2y2-4f3a5719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Columbia Duet Unit B [](https://www.expedia.co.uk/West-Columbia-Hotels-Columbia-Duet-Unit-B.h109292506.Hotel-Information) 1.8 mi from Lexington Medical Center £660 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/West-Columbia-Hotels-Columbia-Duet-Unit-B.h109292506.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/a1a27db5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/e94102a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/21565fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/abbeba1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lexington Expo Hotel by IHG [](https://www.expedia.co.uk/Columbia-Hotels-Wingate-By-Wyndham-Columbia-Lexington.h1823665.Hotel-Information) 2.2 mi from Lexington Medical Center 9.2/10 Wonderful (1,005 reviews) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Konrad £92 includes taxes & fees 14 Feb - 15 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Wingate-By-Wyndham-Columbia-Lexington.h1823665.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/40000000/39640000/39637100/39637010/38e4995a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/40000000/39640000/39637100/39637010/30a1e4b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/40000000/39640000/39637100/39637010/2c8bbdb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/40000000/39640000/39637100/39637010/5c21e195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Columbia Greystone [](https://www.expedia.co.uk/Columbia-Hotels-Tru-By-Hilton-Columbia-Greystone.h39637010.Hotel-Information) 2.4 mi from Lexington Medical Center 9.2/10 Wonderful (1,002 reviews) "Rooms were very clean and updated well. Staff was friendly and breakfast was good. Would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christian £82 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Tru-By-Hilton-Columbia-Greystone.h39637010.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077175/5707016c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077175/8aecb85c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077175/444c8c69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Accessible, Bathtub (Mobility & Hearing) | Living area | 40-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077175/62f712d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Columbia [](https://www.expedia.co.uk/Columbia-Hotels-Homewood-Suites-By-Hilton-Columbia.h1077175.Hotel-Information) 2.3 mi from Lexington Medical Center 8.2/10 Very good (902 reviews) "Everything was perfect." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jhontise £95 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Homewood-Suites-By-Hilton-Columbia.h1077175.Hotel-Information) ![Desk, iron/ironing board, cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/330000/327600/327551/0bb24139.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/330000/327600/327551/cf06a457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/330000/327600/327551/47356c41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327600/327551/w2992h2000x0y0-446feecc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Limited Columbia [](https://www.expedia.co.uk/Columbia-Hotels-Ramada-Limited-Columbia.h327551.Hotel-Information) 2.6 mi from Lexington Medical Center 7.8/10 Good (962 reviews) "Clean room. Friendly staff. Conveniently located for our stop on the drive back home. Enough variety for a quick breakfast before heading out. No complaints. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle £63 includes taxes & fees 11 Feb - 12 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Ramada-Limited-Columbia.h327551.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-22&endDate=2026-02-23®ionId=624549612579786752&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Lexington Medical Center | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/19000000/18230000/18228600/18228549/2dd545dc.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Residence Inn Columbia West/Lexington | 3.0 star property | 9.2Wonderful364 reviews | View | | | | | | | ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3200000/3191900/3191843/8abca080.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hilton Garden Inn Columbia Airport | 3.0 star property | 9.0Wonderful1,001 reviews | View | | | | | | | ![Terrace/patio](https://images.trvl-media.com/lodging/60000000/59790000/59784600/59784598/588e3575.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)TownePlace Suites Columbia West/Lexington | 3.0 star property | 9.2Wonderful460 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/7600/7503/0f42dc03.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn Columbia-I-26 Airport | 2.5 star property | 8.2Very good1,007 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/de238acf.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Sleep Inn Columbia | 2.5 star property | 8.2Very good1,009 reviews | View | | | | | | ## Top Lexington Medical Center Hotel Reviews ![Sleep Inn Columbia](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/de238acf_y.jpg) ### Sleep Inn Columbia 10/10 Excellent "Clean and friendly staff" [](https://expedia.co.uk/Columbia-Hotels-Sleep-Inn-At-Bush-River-Road.h126908.Hotel-Information) ![Hampton Inn Columbia-I-26 Airport](https://images.trvl-media.com/lodging/1000000/10000/7600/7503/e8ace719_y.jpg) ### Hampton Inn Columbia-I-26 Airport 10/10 Excellent "The staff was friendly and accommodating! I also loved the complimentary breakfast offered as well as the other food options in the area. " [](https://expedia.co.uk/Columbia-Hotels-Hampton-Inn-Columbia-I-26-Airport.h7503.Hotel-Information) ![TownePlace Suites Columbia West/Lexington](https://images.trvl-media.com/lodging/60000000/59790000/59784600/59784598/604294a2_y.jpg) ### TownePlace Suites Columbia West/Lexington 10/10 Excellent "Great location near the hospital. Front desk clerk was friendly. Room was comfortable with full sized fridge. " [](https://expedia.co.uk/Columbia-Hotels-TownePlace-Suites-Columbia-WestLexington.h59784598.Hotel-Information) ![Best Western Executive Inn & Suites](https://images.trvl-media.com/lodging/1000000/80000/77800/77728/677018a3_y.jpg) ### Best Western Executive Inn & Suites 10/10 Excellent "great room, great bed, nice staff!" [](https://expedia.co.uk/Columbia-Hotels-Best-Western-Executive-Inn-Suites.h77728.Hotel-Information) ![Baymont by Wyndham Columbia Northwest](https://images.trvl-media.com/lodging/1000000/20000/17600/17541/830f5312_y.jpg) ### Baymont by Wyndham Columbia Northwest 10/10 Excellent "Easy quick check in. Ok room for the price" [](https://expedia.co.uk/Columbia-Hotels-Baymont-By-Wyndham-Columbia-Northwest.h17541.Hotel-Information) ![Lexington Expo Hotel by IHG](https://images.trvl-media.com/lodging/2000000/1830000/1823700/1823665/e611a2e7_y.jpg) ### Lexington Expo Hotel by IHG 10/10 Excellent "Staff was super helpful and nice. Changed rooms because mini fridge was broken but front desk handled the transfer with grace and a smile. " [](https://expedia.co.uk/Columbia-Hotels-Wingate-By-Wyndham-Columbia-Lexington.h1823665.Hotel-Information) ![Cozy 3-bedroom Home in West Columbia located only 5 minutes from downtown vista.](https://images.trvl-media.com/lodging/115000000/114590000/114581100/114581093/d16f2580_y.jpg) ### Cozy 3-bedroom Home in West Columbia located only 5 minutes from downtown vista. 10/10 Excellent "My family and I booked here last minute for a 2 night stay and found it be everything we needed. The location to the interstate, grocery stores, and restaurants was something we greatly appreciated. Finally, the neighborhood is quiet which was a plus for us. " [](https://expedia.co.uk/West-Columbia-Hotels-Cozy-3-Bedroom-Home-In-Awesome-West-Columbia-With-AC.h114581093.Hotel-Information) ![Doubletree by Hilton Columbia, SC](https://images.trvl-media.com/lodging/1000000/10000/1100/1090/db46c2f4_y.jpg) ### Doubletree by Hilton Columbia, SC 10/10 Excellent "Just that the hotel staff were very courteous and provided everything I asked for. " [](https://expedia.co.uk/Columbia-Hotels-Doubletree-By-Hilton-Columbia.h1090.Hotel-Information) ![Executive Inn](https://images.trvl-media.com/lodging/16000000/15880000/15875600/15875546/94dcd5e7_y.jpg) ### Executive Inn 10/10 Excellent "Room was in good condition. Staff really nice. Several restaurants nearby. " [](https://expedia.co.uk/Columbia-Hotels-Executive-Inn.h15875546.Hotel-Information) ## Hotels near other Lexington Medical Center attractions ![Animals in the zoo. Wild African animals in a summer forest on a sunny day. Outdoor activities with children. Riverbanks Zoo and Garden, Columbia, South Carolina, USA. American flamingos in the zoo](https://images.trvl-media.com/place/6082673/ab3425f0-7f32-4cc8-8563-e91db4581d1a.jpg) ### Riverbanks Zoo and Garden 4.4/5 (613 reviews) Why not meet the animals who call Riverbanks Zoo and Garden home during your holiday in Columbia? You can attend a sporting event while in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082673) ![The view at the end of the canal trail from Columbia's Riverfront Park. It is a beautiful city park! For a video guide of the park and trail, please visit: https://www.hdcarolina.com/episode/riverfront-park-canal-trail](https://images.trvl-media.com/place/764/46704b9e-296f-4aee-a53c-75dc6558f08f.jpg) Photo by Ryan Watts ### Columbia Canal and Riverfront Park Explore the great outdoors at Columbia Canal and Riverfront Park, a lovely green space in Columbia. Experience the area's acclaimed theatre scene or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657312) ### AMF Seven Oaks Lanes You can take time to visit AMF Seven Oaks Lanes during your travels to Columbia. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=937304761106280448) ### Riverbanks Botanical Garden 4.2/5 (31 reviews) Explore the great outdoors at Riverbanks Botanical Garden, a lovely green space in West Columbia. Attend a sporting event while you're in the area or simply enjoy its bars. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635973685783) ### BTM Dutch Square Cinema 14 You can take time to visit BTM Dutch Square Cinema 14 during your travels to Columbia. While in this family-friendly area, you can savour the top-notch restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=942319365720989696) ### Oak Grove Softball Complex After visiting Oak Grove Softball Complex, make a plan to see the other sights and activities in Oak Grove. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911210761664438272) ### West Columbia Riverwalk 4.2/5 (74 reviews) Explore the great outdoors at West Columbia Riverwalk, a lovely green space in West Columbia. Attend a sporting event or simply enjoy the lively bars while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657319) ### Columbia Marionette Theater Enjoy a performance at Columbia Marionette Theater, a theatre with a story to tell in Columbia. Experience the area's acclaimed theatre scene or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657295) ## Frequently asked questions ### What's the area like around Lexington Medical Center? ### Where is the best place to stay near Lexington Medical Center? ### How many hotels are there near Lexington Medical Center? ### If I need to cancel the hotel reservation for my stay near Lexington Medical Center, will I receive a refund? ### What can I see and do near Lexington Medical Center?