The Best Hotels Closest to Lewis and Clark Interpretive Center in St. Louis - 2026 Updated Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Save instantly and earn perks with One Key
Learn about One Key
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Lewis and Clark Interpretive Center hotels

A modern living room with a stone fireplace, a reception desk, and a large window.

A modern living room with a stone fireplace, green and beige sofas, a round coffee table, and large windows offering a view of trees.

A modern lobby with a blue sofa, a white coffee table, and a reception desk in the background.

A Fairfield by Marriott hotel with a modern design, featuring a covered entrance and multiple floors.

1. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

3.9 mi from Lewis and Clark Interpretive Center

Sabra

£88

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

An indoor swimming pool with clear glass walls, a tiled edge, and a ceiling with metal beams. There are lounge chairs and tables around the pool area.

A restaurant with a brick wall, large windows, and a seating area with tables and chairs.

A hotel room with a large bed, a desk, a chair, and a television.

2. Drury Inn & Suites St. Louis Collinsville

9.6 mi from Lewis and Clark Interpretive Center

Wayne

£96

includes taxes & fees

11 Oct - 12 Oct

A modern lobby with patterned armchairs, a fireplace, and a large TV on the wall.

A garden with a stone wall, a wooden pergola, and yellow daffodils.

A modern lobby with a blue patterned carpet, a white sofa, patterned armchairs, and a decorative mirror.

A lobby with a sofa, armchairs, a chandelier, decorative mirrors, and a fireplace.

3. Holiday Inn Express & Suites Edwardsville by IHG

6.8 mi from Lewis and Clark Interpretive Center

Mary

£114

includes taxes & fees

25 Oct - 26 Oct

A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

A hotel room with a large bed, two bedside tables, a desk, and a chair.

A reception area with two dark wooden reception desks, a stone-textured wall, and a sign reading "Comfort INN".

A spacious dining area with high tables and booths, large windows, and a view of greenery outside.

4. Comfort Inn Edwardsville - St. Louis

5.9 mi from Lewis and Clark Interpretive Center

Cynthia

£83

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with balconies, a parking lot with marked spaces, and a clear sky.

A hotel room with two beds, each with a wooden headboard, white bedding, and a patterned bedspread.

A long, straight corridor with a series of doors on one side and a black railing on the other.

A reception desk with a 'NO Pets Allowed' sign, a 'Please ring door bell' sign, and a window with a view of a parking lot.

5. Bel Air Motel

3.9 mi from Lewis and Clark Interpretive Center

Tai

£60

includes taxes & fees

28 Sept - 29 Sept

A brick building with a wooden gazebo in front.

A statue of a Native American figure with a horse, a Route 66 sign, a map, and a clock on the wall.

A compact kitchen with a sink, microwave, and stove, a wooden cabinet, and a television mounted on the wall.

A hotel room with two beds, a dresser, a television, and a bathroom visible through an open door.

6. Country Hearth Inn & Suites Edwardsville St. Louis

6.7 mi from Lewis and Clark Interpretive Center

Sarah

£112

includes taxes & fees

28 Sept - 29 Sept

An outdoor patio with a circular fire pit, seating, and a grill area.

A modern kitchen with stainless steel appliances, wooden cabinets, and a countertop with a coffee maker and mugs.

A multi-story hotel with a covered entrance and a sign reading "Towneplace Suites by Marriott".

An indoor swimming pool with clear water, a 15-meter length marker, and a 5-foot depth marker. There are lounge chairs and a table with chairs around the pool.

7. TownePlace Suites by Marriott St. Louis Edwardsville, IL

6.7 mi from Lewis and Clark Interpretive Center

Linda

£152

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a bed, a desk with a TV, a chair, a sofa, and a window with curtains.

8. Hampton Inn & Suites St. Louis/Alton

8.7 mi from Lewis and Clark Interpretive Center

Kathy

£112

includes taxes & fees

4 Oct - 5 Oct

An indoor swimming pool with a lifeguard chair, a lifebuoy, and a mural of a beach scene.

A hotel room with two beds, a desk with a TV, a chair, and a window with a view of the outside.

A breakfast area with a wooden counter, a microwave, and a coffee machine.

A hotel room with a bed, a desk, a chair, a lamp, a mirror, and a television.

9. Super 8 by Wyndham Troy IL/St. Louis Area

11.1 mi from Lewis and Clark Interpretive Center

Jacqueline

£53

includes taxes & fees

4 Oct - 5 Oct

A spacious dining area with high ceilings, multiple dining tables, and chairs.

A Hampton Inn & Suites with a clear entrance, a parking lot, and a flagpole.

A large indoor pool with clear blue water, surrounded by blue walls and windows.

A hotel reception area with a wooden reception desk, a framed picture of a building, and a blue wall with framed items.

10. Hampton Inn & Suites St. Louis-Edwardsville

6.3 mi from Lewis and Clark Interpretive Center

Tashae

£89

includes taxes & fees

12 Oct - 13 Oct

A modern bathroom with a red bathtub, a white sink, and a shower. There is a bed with a white mattress and a grey curtain in the adjacent room.

A modern kitchen area with a dining table and chairs, a refrigerator, a coffee machine, and a vending machine.

A modern kitchen with stainless steel appliances, a white countertop, and a framed picture on the wall.

A spacious interior with a high ceiling, a staircase with wooden balusters, and a modern kitchen area in the background.

11. Red Lion Inn & Suites Pontoon Beach

3.5 mi from Lewis and Clark Interpretive Center

Jennifer

£62

includes taxes & fees

28 Sept - 29 Sept

A hotel room with a bed, a desk with a television, a chair, a desk lamp, and a wall-mounted rack with keys.

A hotel lobby with a reception desk, seating area, and a bakery display.

A swimming pool with a clear blue water, surrounded by lounge chairs and a sunbed.

12. Red Roof Inn St Louis - Troy, IL

11.2 mi from Lewis and Clark Interpretive Center

crystal

£54

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a desk, a chair, and a wall-mounted lamp.

An indoor swimming pool with a lifeguard on duty sign, a pool lift, and chairs around the pool area.

A breakfast station with self-service options, a sign indicating hot food availability, and a digital menu board displaying breakfast items.

13. Holiday Inn Express Troy by IHG

11.2 mi from Lewis and Clark Interpretive Center

Donald

£106

includes taxes & fees

28 Oct - 29 Oct

A buffet area with a wooden counter, various food items, and a coffee station.

A Comfort Inn hotel with a simple facade, a parking lot, and a clear sky in the background.

A hotel room with a sofa, a small table, a lamp, and a TV.

A hotel room with two beds, a sofa, a desk, and a window with curtains.

14. Comfort Inn Collinsville near St. Louis

9.5 mi from Lewis and Clark Interpretive Center

Jose Rene

£93

includes taxes & fees

19 Oct - 20 Oct

An outdoor patio area with multiple tables and chairs, surrounded by neatly trimmed bushes and a gravel path.

A hotel room with a bed, a sofa, a small table, and a painting on the wall.

A modern building with a blue and white color scheme, labeled "The Great Rivers." It features a parking lot with several cars and a gas station in the foreground.

A parking area with electric vehicle charging stations, marked parking spaces, and a chain-link fence.

15. The Great Rivers, an Ascend Collection Hotel

7.1 mi from Lewis and Clark Interpretive Center

Jo Ann

£75

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a bed, a framed cityscape picture, and a view of a cityscape through a window.

A parking lot with a motel building in the background.

A compact room with a kitchenette, a flat-screen TV mounted above the microwave, a small refrigerator, a wooden dresser, and a door leading to a closet with hanging clothes.

A parking lot with several vehicles, including a red pickup truck and a white van, in front of a building with a balcony.

16. Indian Mound Motel

10.4 mi from Lewis and Clark Interpretive Center

paul

£45

includes taxes & fees

5 Oct - 6 Oct

A hotel lobby with a stone fireplace, a dining area with tables and chairs, and a colorful carpet.

A hotel room with a bed, a sofa, two small tables, a chair, and a painting on the wall.

A vending machine with snacks and drinks, a microwave, and a refrigerator.

A modern lobby with a stone accent wall, a blue sofa, and a reception desk.

17. Fairfield Inn by Marriott St. Louis Collinsville, IL

9.5 mi from Lewis and Clark Interpretive Center

David A.

£90

includes taxes & fees

19 Oct - 20 Oct

A lobby with a blue sofa, patterned cushions, a reception desk, and a mural of a moon and arch.

A hotel with a central entrance, multiple floors, and a clear sky.

A breakfast bar with a microwave, coffee makers, and a fruit display.

A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.

18. La Quinta Inn & Suites by Wyndham Pontoon Beach

4.3 mi from Lewis and Clark Interpretive Center

Weldon

£95

includes taxes & fees

28 Sept - 29 Sept

A modern kitchen with marble countertops, a built-in coffee station, and a seating area with metal chairs and tables.

A hotel room with a large bed, a nightstand with a phone, and wall-mounted lights.

A bathroom with a bathtub, toilet, and a towel rack.

A motel with multiple floors, a parking lot, and a clear sky.

19. Days Inn by Wyndham Troy IL

11.2 mi from Lewis and Clark Interpretive Center

Carol

£59

includes taxes & fees

1 Oct - 2 Oct

A hotel room with two beds, a desk, a chair, and a TV.

A hotel dining area with a buffet setup, including coffee makers and a potted plant.

A gazebo with a stone base and a wooden upper structure, surrounded by a garden with pink flowers and trees.

A hotel office with three desks, each with a computer and chair.

20. Hampton Inn Collinsville

9.5 mi from Lewis and Clark Interpretive Center

Ria

£93

includes taxes & fees

28 Oct - 29 Oct

View all properties

Compare popular hotels close to Lewis and Clark Interpretive Center

Property	Property class	Guest rating
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City	9.2 Wonderful 529 reviews	View
Drury Inn & Suites St. Louis Collinsville	9.6 Exceptional 1,002 reviews	View
Holiday Inn Express & Suites Edwardsville by IHG	9.2 Wonderful 911 reviews	View
Comfort Inn Edwardsville - St. Louis	8.4 Very good 951 reviews	View
Bel Air Motel	8.6 Excellent 240 reviews	View

Top Lewis and Clark Interpretive Center Hotel Reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"This was one of the best hotels I have ever stayed at... from the beautiful rooms... to the amazing rooftop bar... to the luxurious CommonWealth. Priceless establishment!"

Renaissance St. Louis Airport Hotel

10/10 Excellent

"Staff was great! Would come back to stay."

Marriott St. Louis Grand

8/10 Good

"Very small room for 2 beds. The bathroom was bigger than the hotel room. Very disappointed."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Great value, free breakfast and free parking, and helpful and friendly staff."

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"I loved that hotel is near the stadium, also the Farris Wheel right in front of the hotel, but the most thing I liked which most hotels don’t have is “ the happy hour“. Your offer for the dinner each day is awesome. Your stuff is amazing, friendly and patient and very hard working. I really appreciate it."

Super 8 by Wyndham St. Louis North

8/10 Good

"Why don't y'all offer any discounts"

Home2 Suites by Hilton St. Louis Downtown

8/10 Good

"No comment"

Four Seasons Hotel St Louis

10/10 Excellent

"This was the nicest hotel I have ever stayed at!"

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"Great experience and walking distance from Cardinals Stadium and Arch"

Other attractions near Lewis and Clark Interpretive Center

Lewis and Clark Confluence Tower

Bring a camera when you climb this tower, which offers fantastic views across the Mississippi River and provides insight into a fascinating piece of history.

See properties

Lewis and Clark State Memorial Park

Explore the great outdoors at Lewis and Clark State Memorial Park, a lovely green space in Hartford. Discover the area's museums and monuments.

See properties

Hartford Park

After visiting Hartford Park, make a plan to see the other sights and activities in Hartford. Discover the area's museums and monuments.

See properties

Hartford City Hall

Hartford City Hall is just one of the places to see in Hartford, so why not enjoy the other things to explore during your travels? Amble around the area's riverfront or experience its museums.

See properties

Jones-Confluence Point State Park

You can take time to visit Jones-Confluence Point State Park during your travels to West Alton. You can attend a sporting event while in the area.

See properties

Dads Club Park

Explore the great outdoors at Dads Club Park, a lovely green space in South Roxana.

See properties

South Roxana Dad's Club Park

South Roxana Dad's Club Park is just one of the places to see in South Roxana, so why not enjoy the other things to explore during your travels?

See properties

Frequently asked questions

What's the area like around Lewis and Clark Interpretive Center?

Lewis and Clark Interpretive Center is located in a welcoming area of Hartford that travellers like for its sporting events. You'll find 12 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to Lewis and Clark Interpretive Center?

Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and 2 bars. You'll find it 13 mi (20.9 km) from Lewis and Clark Interpretive Center. Other good options around the area include Super 8 by Wyndham St. Louis North and Drury Plaza Hotel St. Louis at the Arch.

How many hotels will I find close to Lewis and Clark Interpretive Center?

Expedia has 12 hotels and other accommodation options a few miles from Lewis and Clark Interpretive Center.

If I need to cancel the hotel reservation for my stay near Lewis and Clark Interpretive Center, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals available near Lewis and Clark Interpretive Center.

What can I see and do near Lewis and Clark Interpretive Center?

You might spend a leisurely day outdoors at Lewis and Clark State Memorial Park and Dads Club Park. Create some family memories at CP Pinball and Saint Louis Zoo WildCare Park. Explore nature at Jones-Confluence Point State Park and Columbia Bottom Conservation Area.

Search Hotels Near Lewis and Clark Interpretive Center, St. Louis

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lewis and Clark Interpretive Center hotels

1. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

2. Drury Inn & Suites St. Louis Collinsville

3. Holiday Inn Express & Suites Edwardsville by IHG

4. Comfort Inn Edwardsville - St. Louis

5. Bel Air Motel

6. Country Hearth Inn & Suites Edwardsville St. Louis

7. TownePlace Suites by Marriott St. Louis Edwardsville, IL

8. Hampton Inn & Suites St. Louis/Alton

9. Super 8 by Wyndham Troy IL/St. Louis Area

10. Hampton Inn & Suites St. Louis-Edwardsville

11. Red Lion Inn & Suites Pontoon Beach

12. Red Roof Inn St Louis - Troy, IL

13. Holiday Inn Express Troy by IHG

14. Comfort Inn Collinsville near St. Louis

15. The Great Rivers, an Ascend Collection Hotel

16. Indian Mound Motel

17. Fairfield Inn by Marriott St. Louis Collinsville, IL

18. La Quinta Inn & Suites by Wyndham Pontoon Beach

19. Days Inn by Wyndham Troy IL

20. Hampton Inn Collinsville

Compare popular hotels close to Lewis and Clark Interpretive Center

Top Lewis and Clark Interpretive Center Hotel Reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Renaissance St. Louis Airport Hotel

Marriott St. Louis Grand

Pear Tree Inn St. Louis Airport

Drury Plaza Hotel St. Louis Union Station

Super 8 by Wyndham St. Louis North

Home2 Suites by Hilton St. Louis Downtown

Four Seasons Hotel St Louis

Drury Plaza Hotel St. Louis at the Arch

Other attractions near Lewis and Clark Interpretive Center

Lewis and Clark Confluence Tower

Lewis and Clark State Memorial Park

Hartford Park

Hartford City Hall

Jones-Confluence Point State Park

Dads Club Park

South Roxana Dad's Club Park

Frequently asked questions