Default HTG hotel image

Search Hotels in La Misión, Cajeme

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for La Misión hotels

A modern reception area with a long reception desk, multiple chairs, two monitors, and a potted plant.

1. City Express by Marriott Ciudad Obregón

City Express by Marriott Ciudad Obregón
3.0 star property
3.5 mi from La Misión
8.6 out of 10, Excellent, (971 reviews)
"Everything was excellent"
United States
Roberto
The price is £44
includes taxes & fees
15 Nov - 16 Nov
City Express by Marriott Ciudad Obregón
A Holiday Inn Express & Suites with a covered entrance, palm trees, and a clear sky.

2. Holiday Inn Express & Suites Ciudad Obregon by IHG

Holiday Inn Express & Suites Ciudad Obregon by IHG
3.0 star property
3.2 mi from La Misión
9.4 out of 10, Exceptional, (917 reviews)
"Clean, breakfast was amazing"
United States
Anabel
The price is £83
includes taxes & fees
29 Nov - 30 Nov
Holiday Inn Express & Suites Ciudad Obregon by IHG
A swimming pool surrounded by palm trees and a building with a curved facade.

3. Best Western Plus San Jorge

Best Western Plus San Jorge
3.0 star property
3.4 mi from La Misión
8.4 out of 10, Very good, (621 reviews)
"Stayed in Obregon a few times and this place we liked the best."
United States
John
The price is £57
includes taxes & fees
20 Nov - 21 Nov
Best Western Plus San Jorge
A spacious hotel lobby with multiple dining areas, a visible kitchen area, and a mezzanine level.

4. Wyndham Garden Ciudad Obregon

Wyndham Garden Ciudad Obregon
4.5 star property
2.5 mi from La Misión
8.0 out of 10, Very good, (731 reviews)
"Please do not stay in this Hotel it is dirty and outdated.. It is unfortunate that Wyndham uses their name on this property… The place looks like your in the early 60’s .."
United States
Fernando
The price is £64
includes taxes & fees
14 Nov - 15 Nov
Wyndham Garden Ciudad Obregon
A rooftop pool area with lounge chairs and a pergola structure.

5. Fiesta Inn Express Ciudad Obregón

Fiesta Inn Express Ciudad Obregón
3.5 star property
3.2 mi from La Misión
8.4 out of 10, Very good, (1,000 reviews)
"great place to stay in Obregón... you can enjoy a breakfast (a very mexican one) every morning that will make your day.. you have more options nearby for lunch and dinner too."
United States
Juan Diego
The price is £86
includes taxes & fees
15 Nov - 16 Nov
Fiesta Inn Express Ciudad Obregón
A hotel pool area with a sign reading "InHouse Hotels" and a clear blue sky.

6. InHouse Hotel Obregón

InHouse Hotel Obregón
4.0 star property
3.1 mi from La Misión
8.8 out of 10, Excellent, (485 reviews)
"Excelente personal"
Mexico
esmeralda
The price is £57
includes taxes & fees
6 Dec - 7 Dec
InHouse Hotel Obregón
An outdoor seating area with multiple tables and chairs, a stone wall, and a staircase leading to an upper level.

7. Quality Inn Ciudad Obregon

Quality Inn Ciudad Obregon
3.0 star property
2.6 mi from La Misión
8.0 out of 10, Very good, (685 reviews)
"Great rooms and friendly staff, great breakfast"
Canada
John-Paul
The price is £50
includes taxes & fees
20 Nov - 21 Nov
Quality Inn Ciudad Obregon
A swimming pool with stone pillars, a green car parked nearby, and a building in the background.

8. Hotel Yori

Hotel Yori
3.0 star property
3.3 mi from La Misión
6.6 out of 10, (183 reviews)
"Good experience for the price. Breakfast was reasonable. We would stay there again"
United States
Kevin
The price is £33
includes taxes & fees
13 Dec - 14 Dec
Hotel Yori
Living room

9. Hotel Napoles

Hotel Napoles
2.5 star property
2.8 mi from La Misión
9.0 out of 10, Wonderful, (49 reviews)
"It’s quiet, good location, service is great."
United States
luz
The price is £33
includes taxes & fees
4 Dec - 5 Dec
Hotel Napoles
A single bed with a headboard, two bedside tables, and two wall-mounted lights.

10. Hotel Posada del Yaqui

Hotel Posada del Yaqui
2.5 star property
1.7 mi from La Misión
8.6 out of 10, Excellent, (144 reviews)
"Courteous staff, clean room and delicious food "
Canada
Juan
The price is £29
includes taxes & fees
4 Dec - 5 Dec
Hotel Posada del Yaqui
A kitchen with a dark wooden island, a microwave, and cabinets. There is a chair with a white cushion in front of the island.

11. Hotel Bugambilias

Hotel Bugambilias
2.5 star property
2.6 mi from La Misión
7.8 out of 10, Good, (180 reviews)
"Excelente "
Mexico
José María
The price is £18
includes taxes & fees
14 Nov - 15 Nov
Hotel Bugambilias
A multi-story hotel with balconies, a parking lot, and several cars parked in front.

12. Hotel Obregon

Hotel Obregon
3.0 star property
2.7 mi from La Misión
7.0 out of 10, Good, (93 reviews)
"Like"
Mexico
AxelFms
The price is £37
includes taxes & fees
13 Dec - 14 Dec
Hotel Obregon
A neatly made bed with a dark blue bedspread, a white door, a small table, and a wall-mounted shelf with a plant and a hanger.

13. HOTEL ESPERANZA

HOTEL ESPERANZA
2.0 star property
7.3 mi from La Misión
8.6 out of 10, Excellent, (7 reviews)
"The room ran out of toilet paper before we even went to bed meaning there was not a lot to start with. The water didn’t stay hot long. The hotel is right by the hwy and train tracks IT IS SOOOOOOOO LOUD!!! Didn’t sleep at all neither did my wife or my dog who sleeps like a dead log. There is not a lot around the hotel even though it looks like it on the map. I wouldn’t stay again I would stay in ciudad Obregón instead. The room and property was Decent and clean, staff were nice. Cute little...
Canada
Ashley
The price is £26
includes taxes & fees
13 Nov - 14 Nov
HOTEL ESPERANZA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in La Misión

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A Holiday Inn Express & Suites with a covered entrance, palm trees, and a clear sky.
Holiday Inn Express & Suites Ciudad Obregon by IHG
3.0 star property
9.4
Exceptional
917 reviews
View
A modern reception area with a long reception desk, multiple chairs, two monitors, and a potted plant.
City Express by Marriott Ciudad Obregón
3.0 star property
8.6
Excellent
971 reviews
View
A hotel pool area with a sign reading "InHouse Hotels" and a clear blue sky.
InHouse Hotel Obregón
4.0 star property
8.8
Excellent
485 reviews
View
A swimming pool surrounded by palm trees and a building with a curved facade.
Best Western Plus San Jorge
3.0 star property
8.4
Very good
621 reviews
View
A rooftop pool area with lounge chairs and a pergola structure.
Fiesta Inn Express Ciudad Obregón
3.5 star property
8.4
Very good
1,000 reviews
View

Where to stay in La Misión

Find the best La Misión areas for the activities you enjoy most.

Parque Industrial

If you're looking for some top things to see and do in Parque Industrial and surrounding area, you can visit Sendero Plaza and Plaza Tutuli Shopping Center.

Top La Misión Hotel Reviews

Hotel Posada del Yaqui

Hotel Posada del Yaqui

8/10 Good
"The price and the cleaning!"
Esther 1-night trip
Posted 15 hours ago
Hotel Posada del Yaqui

Frequently asked questions

When is the best time to go to La Misión?
The best time to go to La Misión, Sonora, Mexico, is during the dry season, which runs from October to May, with the peak months being November through April.

During these months, you'll experience pleasant, warm weather with clear skies and minimal rainfall, making it ideal for enjoying the outdoor activities La Misión is known for. Daytime temperatures typically range from 20°C to 28°C, superb for beach strolls, exploring the local area, or simply relaxing by the pool. The evenings are comfortably cooler, often requiring a light jacket.

This period is particularly well-suited for couples seeking a relaxing getaway. The comfortable climate allows for leisurely days on the beach, enjoying al fresco dining, and exploring the charming town without the intensity of summer heat or humidity. Families will also find this time of year excellent for their holidays, as children can enjoy the beach and outdoor activities without discomfort.

While June to September is the rainy season, characterized by higher humidity and occasional afternoon showers, it can still be a good option for those looking for lower prices and fewer crowds, provided they don't mind the possibility of rain.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in La Misión.
How much is the nightly rate at a La Misión hotel?
Hotel prices in La Misión often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.