Title: The Best Hotels in La Misión, Acuña - 2026 Updated Prices | Expedia.co.uk [Holiday Rentals in Acuña](https://expedia.co.uk/Acuna-Holiday-Rentals.d602273.Travel-Guide-HolidayRentals)[La Misión Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Mision.d553248635976399648.Car-Hire-Guide)[La Misión Holidays](https://expedia.co.uk/La-Mision.d553248635976399648.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [27 Feb - 28 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976399648&startDate=2026-02-27&endDate=2026-02-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [28 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976399648&startDate=2026-02-28&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976399648&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976399648&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for La Misión hotels ![Deluxe Apartment, Balcony, City View | Outdoor dining](https://images.trvl-media.com/lodging/126000000/125130000/125123500/125123403/cdde7249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/126000000/125130000/125123500/125123403/0549645d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/126000000/125130000/125123500/125123403/8cb3636d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/126000000/125130000/125123500/125123403/33776d20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Departamentos MateoS 501 [](https://www.expedia.co.uk/Acuna-Hotels-Departamentos-MateoS-501.h125123403.Hotel-Information) 3.2 mi from La Misión £82 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Acuna-Hotels-Departamentos-MateoS-501.h125123403.Hotel-Information) ![Blackout curtains, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/126000000/125130000/125124300/125124270/6e6eb61c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Interior](https://images.trvl-media.com/lodging/126000000/125130000/125124300/125124270/fd1aa65f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/126000000/125130000/125124300/125124270/9d8d57e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Interior](https://images.trvl-media.com/lodging/126000000/125130000/125124300/125124270/1f309fde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Departamentos Mateos 665 [](https://www.expedia.co.uk/Acuna-Hotels-Departamentos-Mateos-665.h125124270.Hotel-Information) 5 mi from La Misión £87 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Acuna-Hotels-Departamentos-Mateos-665.h125124270.Hotel-Information) ![Deluxe Apartment, City View | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/125000000/124400000/124395200/124395132/83667014.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/125000000/124400000/124395200/124395132/aca54a5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124400000/124395200/124395132/abdb940e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/125000000/124400000/124395200/124395132/9547a21c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Departamentos MateoS 504 [](https://www.expedia.co.uk/Acuna-Hotels-Departamentos-MateoS-504.h124395132.Hotel-Information) 3.2 mi from La Misión £72 includes taxes & fees 28 Feb - 1 Mar [](https://www.expedia.co.uk/Acuna-Hotels-Departamentos-MateoS-504.h124395132.Hotel-Information) ![Deluxe Apartment | Living area](https://images.trvl-media.com/lodging/125000000/124400000/124395400/124395307/03b4e634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/125000000/124400000/124395400/124395307/8494c10e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/125000000/124400000/124395400/124395307/8a8845a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/125000000/124400000/124395400/124395307/1cf5e9d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Departamento MateoS 503 [](https://www.expedia.co.uk/Acuna-Hotels-Departamento-MateoS-503.h124395307.Hotel-Information) 3.2 mi from La Misión £66 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Acuna-Hotels-Departamento-MateoS-503.h124395307.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-13&endDate=2026-03-14®ionId=553248635976399648&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top La Misión Hotel Reviews ![Palms Suites](https://images.trvl-media.com/lodging/84000000/83230000/83221200/83221180/e6df999e_y.jpg) ### Palms Suites 10/10 Excellent "Our stay was very pleasant. Very peaceful and felt so secured. We’ll be back to book this place again for sure! " [](https://expedia.co.uk/Acuna-Hotels-CMG-Suites.h83221180.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? ### How can I save on a La Misión hotel booking with Expedia? ### How much is the nightly rate at a La Misión hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - More ways to book - [Acuña Hotels ](https://www.expedia.co.uk/Acuna-Hotels.d602273.Travel-Guide-Hotels) - [Morelos Hotels ](https://www.expedia.co.uk/Morelos-Hotels.d3000425951.Travel-Guide-Hotels) - [Múzquiz Hotels ](https://www.expedia.co.uk/Muzquiz-Hotels.d553248635640633654.Travel-Guide-Hotels) - [Nava Hotels ](https://www.expedia.co.uk/Nava-Hotels.d553248635640673651.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Piedras Negras ](https://www.expedia.co.uk/Piedras-Negras-Hotels-Gay-Friendly-Hotel.0-0-d6052600-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Piedras Negras Hotels ](https://www.expedia.co.uk/Piedras-Negras-Hotels.d6052600.Travel-Guide-Hotels) - [Hotels near Piedras Negras Intl. ](https://www.expedia.co.uk/Piedras-Negras-Intl-Airport-Hotels.0-aPDS-0.Travel-Guide-Filter-Hotels) - [Villa Unión Hotels ](https://www.expedia.co.uk/Villa-Union-Hotels.d553248635640678083.Travel-Guide-Hotels) - [Flights to Piedras Negras ](https://www.expedia.co.uk/Cheap-Flights-To-Piedras-Negras.d6052600.Travel-Guide-Flights) - [Acuña Holidays ](https://www.expedia.co.uk/Acuna.d602273.Holidays-City-Breaks) - [Visit Allende ](https://www.expedia.co.uk/Allende.dx553248635640642434) - [Visit Piedras Negras ](https://www.expedia.co.uk/Piedras-Negras.dx6052600) - [Suv Car Hire in Acuña ](https://www.expedia.co.uk/SUV-Car-Rentals-In-Acuna.d602273-tSUV.Car-Rental-Guide-Class) - [Book Hotels in La Misión on Expedia.mx ](https://www.expedia.mx/La-Mision-Acuna-Hoteles.0-n553248635976399648-0.Guia-Viajes-Filter-Hoteles)