La Mesa Holidays from £1,070

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Your La Mesa Holiday

Lock in a La Mesa holiday package that includes everything you need and nothing you don't. Good for gift and craft shops, dining and nightlife, think about staying in the neighbourhood of Downtown San Diego. The Magnolia, Santee Lakes and Grossmont College are just a few of the attractions you'll want to explore during your trip to La Mesa. Browse Expedia's wide range of travel options and start organising your perfect holiday to La Mesa today.

Top La Mesa Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Price was £1,730, price is now £1,070 per person
£1,070
per person
28 Jun - 5 Jul
found 14 hours ago
Return direct flight included
London (LHR) to San Diego (SAN)
8.6/10 Excellent! (1,969 reviews)
The staff at the desk were so nice sets the tone for the entire stay will definitely be staying here again

Reviewed on 4 May 2026

Ancora by Avantstay Multi-room Reservation Luxury Resort Pool + Sky Deck Walkable Little Italy

Ancora by Avantstay Multi-room Reservation Luxury Resort Pool + Sky Deck Walkable Little Italy

4 out of 5
Downtown San Diego
Save 100% on your flight
Price was £5,962, price is now £4,189 per person
£4,189
per person
28 Jun - 5 Jul
found 14 hours ago
Return direct flight included
London (LHR) to San Diego (SAN)
No reviews
Fairmont Grand Del Mar

Fairmont Grand Del Mar

5 out of 5
Carmel Valley
Save 100% on your flight
Price was £3,246, price is now £2,338 per person
£2,338
per person
28 Jun - 5 Jul
found 14 hours ago
Return direct flight included
London (LHR) to San Diego (SAN)
9.4/10 Exceptional! (972 reviews)
Had an amazing stay!

Reviewed on 24 Feb 2026

Rancho Bernardo Inn

Rancho Bernardo Inn

4 out of 5
Rancho Bernardo
Price was £2,169, price is now £1,596 per person
£1,596
per person
28 Jun - 5 Jul
found 14 hours ago
Return direct flight included
London (LHR) to San Diego (SAN)
8.8/10 Excellent! (1,001 reviews)
Beautiful room, delicious food, outstanding service. My deep tissue massage and facial at the spa were amazing!

Reviewed on 30 Apr 2026

The Artifact Inn

The Artifact Inn

2 out of 5
Downtown San Diego
Price was £2,173, price is now £1,625 per person
£1,625
per person
13 Jun - 20 Jun
found 1 day ago
Return flight included
London (LON) to San Diego (SAN)
9.2/10 Wonderful! (71 reviews)
Clean rooms and close to downtown. I highly recommend this place to anyone. It was amazing. Will definitely be back.

Reviewed on 30 Apr 2026

La Mesa Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Diego Intl. Airport (SAN)
Population
60,100
Max Temp Winter
18ºC
Max Temp Summer
27ºC
Top Sights
San Diego Zoo, Coronado Beach and Old Town San Diego State Park

Top hotels in La Mesa

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is £189 per night from 10 May to 11 May
£189
10 May - 11 May
includes taxes & fees
9/10 Wonderful! (3,630 reviews)
Location and bar

Reviewed on 5 May 2026

Hard Rock Hotel San Diego
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
The price is £124 per night from 11 May to 12 May
£124
11 May - 12 May
includes taxes & fees
8.6/10 Excellent! (2,002 reviews)
Cute little older hotel. Close to everything we wanted to do

Reviewed on 5 May 2026

The Sofia Hotel
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
The price is £109 per night from 25 May to 26 May
£109
25 May - 26 May
includes taxes & fees
8.8/10 Excellent! (1,510 reviews)
The hotel room was nice and the hotel staff was friendly.

Reviewed on 5 May 2026

The DEXTRO Little Italy, BW Premier Collection
See all 8,425 properties in La Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Popular places to visit

Mount Helix Park

Learn about the local history of Casa de Oro-Mount Helix with a stop at Mount Helix Park. Amble around this family-friendly area's waterfront or attend a sporting event.

Mount Helix Park

What to do in La Mesa

LEGOLAND® California Resort

LEGOLAND® California Resort

£66
per adult
84% of travellers recommend
LEGOLAND® California Resort
San Diego: Luggage Storage in Marina

San Diego: Luggage Storage in Marina

£7
per adult
80% of travellers recommend
San Diego: Luggage Storage in Marina
San Diego City Lights Night Tour

San Diego City Lights Night Tour

£36
per adult
96% of travellers recommend
San Diego City Lights Night Tour
See all activities in La Mesa

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.