The Best Hotels Closest to Knapp Medical Center in Weslaco - 2026 Updated Prices

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Our top choices for Knapp Medical Center hotels

A modern kitchen with grey cabinets, stainless steel appliances, and a dining area with a glass table and chairs.

A modern kitchen with stainless steel appliances, a dining table with chairs, and a potted plant.

A modern building with a covered walkway and a parking lot.

A modern bedroom with a bed, nightstands, a dresser, a mirror, and a decorative wall piece.

1. Elegant Apartment 10 min to Mercedes Outlets

1.5 mi from Knapp Medical Center

kraig

£108

includes taxes & fees

15 Sept - 16 Sept

A bed with white bedding and pillows against a wooden headboard.

A hotel room with a blue sofa, a wooden coffee table, and two framed abstract artworks on the wall.

A reception area with a glass partition, a reception desk, a black leather chair, and a tiled floor.

A coffee station with two coffee machines, a coffee press, and various coffee-related items.

2. Holiday Inn Express Hotel & Suites Weslaco by IHG

1.4 mi from Knapp Medical Center

Alnoor

£73

includes taxes & fees

11 Oct - 12 Oct

A hotel with a swimming pool, lounge chairs, and palm trees.

A fitness room with a treadmill, exercise bike, and fan.

A kitchenette with a coffee machine, microwave, toaster, and various appliances.

A hotel room with two beds, a desk with a coffee machine, a trash bin, and framed pictures on the wall.

3. Super 8 by Wyndham Weslaco

1.2 mi from Knapp Medical Center

Luis

£49

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a bed, bedside table, and a small table with a chair.

A yellow building with a covered entrance and a garden in front.

A spacious dining area with multiple round tables and chairs, a stone wall, and a reception desk.

A hotel sign, a parking lot, and a building with a tiled roof.

4. Weslaco Inn Weslaco/Mercedes

0.8 mi from Knapp Medical Center

Bartolo

£56

includes taxes & fees

15 Sept - 16 Sept

A library with bookshelves, a globe, and a mural.

A brick building with a glass door and windows, a concrete ground, and a small awning.

A spacious kitchen with a dining area, a ceiling fan, and a view of the outside.

A hotel room with two beds, a desk, a chair, and a TV.

5. Vali Ho Motel By OYO Weslaco Mercedes

0.6 mi from Knapp Medical Center

William

£45

includes taxes & fees

24 Sept - 25 Sept

A restaurant interior with a seating area, tables, and a counter.

A modern interior with a reception desk, a black couch, and a dining area with chairs and tables.

A modern bathroom with a granite countertop sink, a large mirror, and a coffee machine.

A modern interior with a counter, seating area, and a TV screen.

6. Express Inn

1.3 mi from Knapp Medical Center

Kassandra

£50

includes taxes & fees

13 Sept - 14 Sept

A modern kitchen with a dining area, featuring stainless steel appliances, grey cabinets, and a black dining table with chairs.

A modern living room with a dark-colored sofa, a small wooden side table, and a TV mounted on the wall.

A bedroom with two beds, a nightstand, a wall-mounted tree decoration, and two white doors.

A white door with a 'D' marking, a doormat with 'Welcome' written on it, a blue window with blinds, and a wall-mounted light fixture.

7. Apartment With 3 Bedrooms 40 Minutes From South Padre

1.5 mi from Knapp Medical Center

Julia

£109

includes taxes & fees

13 Sept - 14 Sept

A modern living room with a flat-screen TV, two light blue armchairs, a brown sofa, and a glass coffee table.

A modern kitchen with a marble countertop, four red velvet chairs with gold legs, and stainless steel appliances.

A modern bedroom with a four-poster bed, a ceiling fan, a bedside table with a lamp, a bench, and a chair.

8. Beautiful Apartment 9 min to Mercedes Outlets

1.5 mi from Knapp Medical Center

Jorge

£111

includes taxes & fees

15 Sept - 16 Sept

A modern snack area with a refrigerator, shelves stocked with snacks, and a sign indicating the location.

A hotel room with a bed, a desk with a TV, a kitchenette, a bathroom, and a living area with a sofa and lamp.

A modern hotel with a prominent "HOME 2" sign, a covered entrance, and a well-lit facade.

9. Home2 Suites By Hilton San Juan

10.3 mi from Knapp Medical Center

Latasha

£70

includes taxes & fees

20 Sept - 21 Sept

A breakfast buffet area with a sign that reads "HAPPY BREAKFAST STARTS HERE."

A pool area with lounge chairs, a stone wall, and palm trees in the background.

A hotel reception desk with a 'Welcome to the Lone Star' sign, a 'Hilton Honors' badge, and a 'Suite Shop' sign.

A hotel room with two beds, a desk, a chair, and a large window.

10. Hampton Inn Weslaco

2.6 mi from Knapp Medical Center

Jorge

£81

includes taxes & fees

20 Sept - 21 Sept

A modern hotel lobby with a bar area, seating, and a television.

A hotel with a red roof and a green sign indicating it is a Marriott hotel. There are palm trees and a well-maintained lawn in front.

A spacious living area with a kitchen, bar area, and seating.

A modern living area with a sofa, chairs, a coffee table, and a decorative vase.

11. La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall

6.1 mi from Knapp Medical Center

Eliseo

£69

includes taxes & fees

13 Sept - 14 Sept

A breakfast buffet area with various food items and a sign that reads "HAPPY BREAKFAST STARTS HERE".

A pool area with lounge chairs, a pool, and palm trees.

A hotel room with two beds, a desk, a chair, a large window, and a radiator.

12. Hampton Inn Weslaco

2.6 mi from Knapp Medical Center

Isaac

£81

includes taxes & fees

19 Sept - 20 Sept

A hotel room with a bed, a desk, a chair, a table, a ceiling fan, a TV, and a door.

A bathroom with a bathtub, shower, and toilet.

A small kitchenette with a microwave, a sink, and a cabinet. There is a framed picture on the wall and a tiled backsplash.

13. Texas Inn Donna

4.3 mi from Knapp Medical Center

Lisa

£52

includes taxes & fees

12 Oct - 13 Oct

A hotel dining area with wooden tables and chairs, a central bar, and a kitchen in the background.

A Comfort Inn & Suites with a pool area featuring lounge chairs and a stone facade.

A multi-story Comfort Inn & Suites with a covered entrance, palm trees, and a parking lot.

A hotel lobby with a Christmas tree, a blue sofa, two armchairs, a small table with a lamp, and a wooden door labeled "Office".

14. Comfort Inn & Suites Donna near I-2

5.4 mi from Knapp Medical Center

maria

£60

includes taxes & fees

4 Oct - 5 Oct

A modern building with a red and beige facade, large windows, and a parking lot with several cars.

A hotel reception area with a glass door entrance, a reception desk, and a sign promoting a mobile app.

A Taco Palenque restaurant with a parking lot and a building with a 'NOW OPEN' sign.

A swimming pool with a metal ladder, a lifeguard chair, and a red building in the background.

15. Motel 6 Weslaco, TX

2.1 mi from Knapp Medical Center

Eugenio

£53

includes taxes & fees

24 Sept - 25 Sept

A modern lobby with a reception desk, blue seating area, and a kitchen in the background.

A Best Western hotel with a brick facade, multiple windows, and a clear sky.

A modern kitchen with a central island, dark cabinetry, and a purple accent wall.

A hotel room with a blue sofa, a wooden coffee table, a patterned carpet, and framed artwork on the walls.

16. Best Western Town Center Inn

2.4 mi from Knapp Medical Center

Benjamin

£74

includes taxes & fees

23 Sept - 24 Sept

A spacious indoor area with multiple tables and chairs, large windows, and a ceiling fan.

A hotel room with a bed, a chair, a nightstand with a lamp, a vanity with a mirror and lights, and a framed picture on the wall.

A brick building with a brown awning labeled 'Victoria Restaurant.' There are palm trees and a parking lot in front.

A spacious room with a wooden floor, a large chandelier, and a modern ceiling design.

17. Victoria Palms Inn & Suites

3.3 mi from Knapp Medical Center

raudel

£48

includes taxes & fees

14 Sept - 15 Sept

A breakfast bar with various food items and a beverage dispenser.

A reception desk with a stone facade, a glass partition, and a sign for Quality Inn & Suites.

A lobby with seating, a Pepsi refrigerator, snack shelves, and a digital kiosk.

A hotel room with a bed, a nightstand, a lamp, a sofa, a ceiling fan, and a door.

18. Quality Inn & Suites at The Outlets Mercedes/Weslaco

5.4 mi from Knapp Medical Center

Martin

£55

includes taxes & fees

4 Oct - 5 Oct

A Rodeway Inn with a covered entrance, palm trees, and a clear blue sky.

A hotel room with two beds, each with patterned bedspreads, a nightstand with a lamp, and two framed pictures on the wall.

A reception area with a wooden counter, a framed picture on the wall, and a sign about rewards.

A hotel room with a large bed, two bedside tables with lamps, and two framed pictures on the wall.

19. Rodeway Inn San Juan

11.5 mi from Knapp Medical Center

Danielle

£38

includes taxes & fees

4 Oct - 5 Oct

A bathroom with a granite countertop, a sink, and a mirror. There are towels hanging on a rack, a shower curtain rod, and a trash bin.

A reception area with a glass door entrance, a reception desk, a ceiling fan, and a Christmas tree.

A building with a sign reading "TEXAS INN" and a garden with red roses in front.

A parking lot with multiple cars and a swimming pool.

20. Texas Inn La Feria

9.6 mi from Knapp Medical Center

Dale

£61

includes taxes & fees

13 Sept - 14 Sept

View all properties

Compare popular hotels close to Knapp Medical Center

Property	Property class	Guest rating
Elegant Apartment 10 min to Mercedes Outlets	9.8 Exceptional 6 reviews	View
Holiday Inn Express Hotel & Suites Weslaco by IHG	9.0 Wonderful 1,000 reviews	View
Super 8 by Wyndham Weslaco	8.8 Excellent 1,001 reviews	View
Weslaco Inn Weslaco/Mercedes	8.4 Very good 653 reviews	View
Vali Ho Motel By OYO Weslaco Mercedes	8.4 Very good 235 reviews	View

Top Knapp Medical Center Hotel Reviews

Rodeway Inn San Juan

8/10 Good

"The only thing was that breakfast was not served at the time they said it was on a Saturday."

Wyndham Garden McAllen at La Plaza Mall

10/10 Excellent

"Nice"

Motel 6 Weslaco, TX

10/10 Excellent

"Liked the fact the room was nice and clean."

La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall

8/10 Good

"Nice hotel"

Best Western Town Center Inn

10/10 Excellent

"O"

Texas Inn Donna

10/10 Excellent

"Our Stay was Great! Clean, Comfortable rooms. Parking was conveniently in front of our room. Convenient access to Highway."

Holiday Inn Express Hotel & Suites Pharr by IHG

10/10 Excellent

"Excellent staff"

La Quinta Inn & Suites by Wyndham Pharr RGV Medical Center

10/10 Excellent

"Stephanie is awesome really clean breakfast is Gretel"

Quality Inn & Suites at The Outlets Mercedes/Weslaco

10/10 Excellent

"Clean room and great parking lot"

Frequently asked questions

What's the area like around Knapp Medical Center?

Knapp Medical Center is located in a budget-friendly area of Weslaco that travellers like for its cathedral. If you're looking for a convenient place to stay, take a look at the 21 hotels and other accommodation options you'll find within a mile.

What's the best place to stay close to Knapp Medical Center?

Weslaco Inn Weslaco/Mercedes is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. It's located just a short 0.8 mi (1.4 km) from Knapp Medical Center. Other good options within 5 miles include Super 8 by Wyndham Weslaco and Holiday Inn Express Hotel & Suites Weslaco by IHG.

How many hotels should I expect to find near Knapp Medical Center?

Expedia has 21 hotels and other accommodation options within a mile from Knapp Medical Center.

If I need to cancel the hotel reservation for my stay near Knapp Medical Center, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review top deals close to Knapp Medical Center.

Search Hotels Near Knapp Medical Center, Weslaco

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Our top choices for Knapp Medical Center hotels

1. Elegant Apartment 10 min to Mercedes Outlets

2. Holiday Inn Express Hotel & Suites Weslaco by IHG

3. Super 8 by Wyndham Weslaco

4. Weslaco Inn Weslaco/Mercedes

5. Vali Ho Motel By OYO Weslaco Mercedes

6. Express Inn

7. Apartment With 3 Bedrooms 40 Minutes From South Padre

8. Beautiful Apartment 9 min to Mercedes Outlets

9. Home2 Suites By Hilton San Juan

10. Hampton Inn Weslaco

11. La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall

12. Hampton Inn Weslaco

13. Texas Inn Donna

14. Comfort Inn & Suites Donna near I-2

15. Motel 6 Weslaco, TX

16. Best Western Town Center Inn

17. Victoria Palms Inn & Suites

18. Quality Inn & Suites at The Outlets Mercedes/Weslaco

19. Rodeway Inn San Juan

20. Texas Inn La Feria

Compare popular hotels close to Knapp Medical Center

Top Knapp Medical Center Hotel Reviews

Rodeway Inn San Juan

Wyndham Garden McAllen at La Plaza Mall

Motel 6 Weslaco, TX

La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall

Best Western Town Center Inn

Texas Inn Donna

Holiday Inn Express Hotel & Suites Pharr by IHG

La Quinta Inn & Suites by Wyndham Pharr RGV Medical Center

Quality Inn & Suites at The Outlets Mercedes/Weslaco

Frequently asked questions