Isla del Rey Holiday Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

The Latest Isla del Rey Holiday Packages

Price found within the past 48 hours. Click for updated prices.
  • 1 Sept - 5 Sept

    Riande Aeropuerto Hotel & Casino + Flight

    Tocumen
    4 nights
    4.0 star property
    8.4/10 - Very good (1,809 reviews)
    Return Georgetown (GEO) - Panama City (PTY)
    GEO - PTYDirect PTY - GEO1 stop
    £821
    £599
    per traveller
    found 1 day ago
    Riande Aeropuerto Hotel & Casino
  • 11 Sept - 16 Sept

    Central Hotel Panama Casco Viejo + Flight

    Casco Viejo
    5 nights
    4.0 star property
    9.2/10 - Wonderful (1,005 reviews)
    "The staff are very professional and helpful; the property is in excellent condition."
    Reviewed August 1, 2026
    Return Georgetown (GEO) - Panama City (PTY)
    GEO - PTYDirect PTY - GEODirect
    Save 100% on your flight
    £1,244
    £716
    per traveller
    found 1 day ago
    Central Hotel Panama Casco Viejo
  • 1 Sept - 5 Sept

    Megapolis Hotel Panamá + Flight

    San Francisco
    4 nights
    4.5 star property
    8.4/10 - Very good (1,626 reviews)
    "Buen servicion el hotel en perfecta condiciones 10 de 10"
    Reviewed August 2, 2026
    Return Georgetown (GEO) - Panama City (PTY)
    GEO - PTYDirect PTY - GEO1 stop
    £1,193
    £817
    per traveller
    found 1 day ago
    Megapolis Hotel Panamá
  • 1 Sept - 5 Sept

    Decapolis Hotel Panama City + Flight

    San Francisco
    4 nights
    4.0 star property
    8.6/10 - Excellent (1,718 reviews)
    Return Georgetown (GEO) - Panama City (PTY)
    GEO - PTYDirect PTY - GEO1 stop
    £855
    £644
    per traveller
    found 1 day ago
    Decapolis Hotel Panama City
  • 2 Oct - 8 Oct

    Victoria Hotel and Suites Panama + Flight

    Bella Vista
    6 nights
    3.5 star property
    8.2/10 - Very good (1,000 reviews)
    "My stay at this hotel was 9 nights and i extended another 3 day/nights . The breakfast was almost the same everyday,upon asking if they do have different stuff i was told No thats what they select. All the staff was good throughout my stay except the receptionist who gave out my info to persons at the front desk mind you they werent staying there .i felt unsafe"
    Reviewed July 29, 2026
    Return Georgetown (GEO) - Panama City (PTY)
    GEO - PTYDirect PTY - GEO1 stop
    £784
    £612
    per traveller
    found 2 days ago
    Victoria Hotel and Suites Panama

Isla del Rey Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

Why should I book my Isla del Rey holiday with Expedia?

Expedia has you covered for all aspects of your Isla del Rey getaway. You'll always land the best deals around, but when you bundle your hotel, flights and/or car hire into a holiday package, you'll get even more savings. Looking to truly make the most of your break? Add a few fun activities and tours to your customised package. Expedia offers flexible cancellation policies on most bookings, so there's no need to stress if you have to change your plans. Head over to our Customer Service Portal link to find out more.

When is the best time of year to holiday in Isla del Rey?

If you love the excitement that comes with peak season, travel to Isla del Rey in March, May and October. Travelling during the quieter months of January, July and December will help you avoid the crowds. With daytime average temperatures of 25ºC, January is the coolest month in Isla del Rey. The warmest month is April, when you can expect average temperatures of 27ºC during the day. Whatever the weather conditions, you'll find plenty to keep you occupied here.

How do I get a cheap holiday to Isla del Rey?

Combining your flight and hotel with Expedia won't just save you time — it'll save you cash too. An Isla del Rey holiday makes it simple to organise your dream adventure. With more than 400 airlines throughout the world to select from, finding convenient flights that fit your busy schedule won't be a hassle. On top of that, we have over 321,000 hotels globally to select from. Now that's what we call choice. No matter who you are, Expedia can show you the world. Learn more about how you can save money on your next holiday when you combine your flight and hotel bookings with Expedia.

Do I need a visa for my Isla del Rey holiday?

Official government websites will have all the information you need on visa requirements, application procedures and necessary documentation. Your nationality and the purpose of your visit, whether it be for holidays or business, will determine if you need a visa for Isla del Rey. Also ensure your passport is up to date and has at least six months validity remaining beyond your return date. Finalise all your travel planning well ahead of time to avoid any nasty last-minute surprises.

What should I wear on my Isla del Rey holiday?

Do some research into the sorts of things people in Isla del Rey wear, and maybe even look up fashion pages on social media for inspiration. You'll want to create a versatile wardrobe full of pieces that suit your destination and showcase your unique sense of style. The weather will influence your choice of clothing, so monitor the forecasts for the places you'll be travelling to. Isla del Rey is at its warmest in April, with average daytime temperatures of 27ºC. January is the coolest time of year here with the mercury averaging 25ºC in the daytime.

What does an Expedia Isla del Rey holiday include?

Choose from a combination of flights, hotels and hire cars. Once you've made your booking, add some experiences and tours. Want to pick your airfare class? That's also easy to do. The choice is yours when it comes to putting together your dream Isla del Rey getaway. With Expedia you'll always have the flexibility to personalise your holiday in Isla del Rey. And when it comes to properties, we've got a variety of styles. Many visitors to this exciting destination opt to stay in hotels.

Does Expedia offer Book Now, Pay Later Isla del Rey holidays?

Yes, we do. Expedia has teamed up with online lender Klarna to help you conveniently pay for your holiday in manageable instalments. Simply select the payment plan that suits best during the checkout process and take away the stress of budgeting for your next trip. Remember to bundle your flights, car hire and hotel with Expedia to get the biggest bang for your buck. Check out our flexible payment options below:

  • Pay monthly holidays: Klarna offers manageable monthly payment plans that work for all budget sizes, so you can escape on that well-deserved holiday now.
  • No-deposit holidays: If not paying upfront for your trip makes hitting that "book now" button more stress-free, go for a no-deposit holiday plan with Klarna so you can Book Now, Pay Later!

Can I choose my airline with an Isla del Rey Expedia holiday?

Yes, you're in control. We have access to over 400 partner airlines worldwide, so you can design your Isla del Rey adventure according to your budget and needs.