Title: Isernia Holiday Homes from £53: Search Holiday Homes in Isernia | Expedia.co.uk [Isernia Travel Guide](https://expedia.co.uk/Isernia.dx6123603)[Hotels in Isernia](https://expedia.co.uk/Isernia-Hotels.d6123603.Travel-Guide-Hotels)[Holiday Rentals in Isernia](https://expedia.co.uk/Isernia-Holiday-Rentals.d6123603.Travel-Guide-HolidayRentals)[Flights to Isernia](https://expedia.co.uk/Cheap-Flights-To-Isernia.d6123603.Travel-Guide-Flights)[Isernia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Isernia.d6123603.Car-Hire-Guide)[Isernia Holidays](https://expedia.co.uk/Isernia.d6123603.Holidays-City-Breaks) ![Pesche - Panoramica dai vicoli](https://images.trvl-media.com/place/6123603/46b9e970-ecd0-4568-9acd-668fde8713e6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6123603/46b9e970-ecd0-4568-9acd-668fde8713e6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6123603&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [24 Apr - 26 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6123603&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [22 May - 24 May](https://www.expedia.co.uk/Hotel-Search?regionId=6123603&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [19 Jun - 21 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=6123603&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Isernia holiday homes ![Terrace/patio](https://images.trvl-media.com/lodging/110000000/109120000/109110900/109110821/9a972550.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/110000000/109120000/109110900/109110821/50f49837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109120000/109110900/109110821/8d0d390f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109120000/109110900/109110821/9786bef7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Alley [](https://www.expedia.co.uk/Isernia-Hotels-The-Alley.h109110821.Hotel-Information) Isernia £150 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Isernia-Hotels-The-Alley.h109110821.Hotel-Information) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114270000/114266500/114266475/65b38fb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/115000000/114270000/114266500/114266475/ca78f000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/115000000/114270000/114266500/114266475/58c5c387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/115000000/114270000/114266500/114266475/3de1fe10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cassino-two-room apartment-park rondo [](https://www.expedia.co.uk/Cassino-Hotels-Cassino-Two-Room-Apartment-Park-Rondo.h114266475.Hotel-Information) Cassino £129 includes taxes & fees 27 Feb - 28 Feb [](https://www.expedia.co.uk/Cassino-Hotels-Cassino-Two-Room-Apartment-Park-Rondo.h114266475.Hotel-Information) ![1 bedroom, free WiFi](https://images.trvl-media.com/lodging/45000000/44970000/44963900/44963819/90-75a69e1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/45000000/44970000/44963900/44963819/90-bc707c6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/45000000/44970000/44963900/44963819/90-6bc083a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/45000000/44970000/44963900/44963819/180-e69328c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Colonial house Ciociara [](https://www.expedia.co.uk/Cervaro-Hotels-Colonial-House-Ciociara.h44963819.Hotel-Information) Cervaro £53 includes taxes & fees 27 Feb - 28 Feb [](https://www.expedia.co.uk/Cervaro-Hotels-Colonial-House-Ciociara.h44963819.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/107000000/106440000/106437100/106437003/17883f37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106440000/106437100/106437003/56c66670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/107000000/106440000/106437100/106437003/79f366a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106440000/106437100/106437003/3bf344a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Home Tenuta Fortilù [](https://www.expedia.co.uk/Santa-Maria-Del-Molise-Hotels-Tenuta-Fortilu-Entire-Villa-Exclusively-With-Private-Pool.h106437003.Hotel-Information) Santa Maria del Molise £415 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Santa-Maria-Del-Molise-Hotels-Tenuta-Fortilu-Entire-Villa-Exclusively-With-Private-Pool.h106437003.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/104000000/103360000/103358400/103358356/cc55ae24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103360000/103358400/103358356/61d0b961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/104000000/103360000/103358400/103358356/4be59816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103360000/103358400/103358356/c46a028d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Tana degli Orsetti Barrea (AQ) (open-air museum) overlooking the lake [](https://www.expedia.co.uk/Barrea-Hotels-La-Tana-Degli-Orsetti-Barrea.h103358356.Hotel-Information) Barrea £272 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Barrea-Hotels-La-Tana-Degli-Orsetti-Barrea.h103358356.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/117000000/116510000/116500200/116500169/dc69837f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/117000000/116510000/116500200/116500169/w1170h1462x0y19-e7c01c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/117000000/116510000/116500200/116500169/9c80ea7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116510000/116500200/116500169/w1200h1597x0y0-bbfa52b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jenny's House 5 minutes from the A1 Caianello exit. [](https://www.expedia.co.uk/Marzano-Appio-Hotels-Jennys-House-5-Minutes-From-The-A1-Caianello-Exit.h116500169.Hotel-Information) Campania £71 includes taxes & fees 28 Feb - 1 Mar [](https://www.expedia.co.uk/Marzano-Appio-Hotels-Jennys-House-5-Minutes-From-The-A1-Caianello-Exit.h116500169.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/115000000/114300000/114294700/114294644/233f3597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel cot, WiFi](https://images.trvl-media.com/lodging/115000000/114300000/114294700/114294644/eef292d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114300000/114294700/114294644/f901e60b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/115000000/114300000/114294700/114294644/91f01bfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Largo Zeza Fifteen Holiday Home [](https://www.expedia.co.uk/Bojano-Hotels-Vrbo-Property.h114294644.Hotel-Information) Bojano £360 includes taxes & fees 27 Feb - 28 Feb [](https://www.expedia.co.uk/Bojano-Hotels-Vrbo-Property.h114294644.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120457900/120457894/ca69d2e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120460000/120457900/120457894/937192a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120460000/120457900/120457894/f0177f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, bidet, towels](https://images.trvl-media.com/lodging/121000000/120460000/120457900/120457894/b3ee10ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Delle Fate [](https://www.expedia.co.uk/San-Gregorio-Matese-Hotels-Vrbo-Property.h120457894.Hotel-Information) Gallo Matese £178 includes taxes & fees 12 Mar - 13 Mar [](https://www.expedia.co.uk/San-Gregorio-Matese-Hotels-Vrbo-Property.h120457894.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/36000000/35850000/35845300/35845272/dece4af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/36000000/35850000/35845300/35845272/809501f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/36000000/35850000/35845300/35845272/77fb7ddb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/36000000/35850000/35845300/35845272/w1751h1187x0y4-cd022bee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Restored farmhouse in the Molise countryside [](https://www.expedia.co.uk/Vinchiaturo-Hotels-Restored-Farmhouse-In-The-Molise-Countryside.h35845272.Hotel-Information) Vinchiaturo £597 includes taxes & fees 27 Feb - 28 Feb [](https://www.expedia.co.uk/Vinchiaturo-Hotels-Restored-Farmhouse-In-The-Molise-Countryside.h35845272.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/98000000/97330000/97322100/97322053/bc6ac6e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/98000000/97330000/97322100/97322053/067aad20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/98000000/97330000/97322100/97322053/3acc30bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/98000000/97330000/97322100/97322053/fa8c61a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home "Residence Fonte Eremita" with Mountain View, Shared Garden & Wi-Fi [](https://www.expedia.co.uk/Roccaraso-Hotels-Vacation-Home-Residence-Fonte-Eremita-With-Mountain-View.h97322053.Hotel-Information) Roccaraso £582 includes taxes & fees 27 Feb - 28 Feb [](https://www.expedia.co.uk/Roccaraso-Hotels-Vacation-Home-Residence-Fonte-Eremita-With-Mountain-View.h97322053.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-12&endDate=2026-03-13®ionId=6123603&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AA_SPRING_PROMO_6123603) ## Find holiday rentals that suit your style Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Isernia%2C+Molise%2C+Italy®ionId=6123603&latLong=41.596043%2C14.233161&adults=2&startDate=2026-05-27&d1=2026-05-27&endDate=2026-05-30&d2=2026-05-30&lodging=APARTMENT) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Isernia%2C+Molise%2C+Italy®ionId=6123603&latLong=41.596043%2C14.233161&adults=2&startDate=2026-05-27&d1=2026-05-27&endDate=2026-05-30&d2=2026-05-30&lodging=VACATION_HOME) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=Isernia%2C+Molise%2C+Italy®ionId=6123603&latLong=41.596043%2C14.233161&adults=2&startDate=2026-05-27&d1=2026-05-27&endDate=2026-05-30&d2=2026-05-30&lodging=VILLA) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Isernia%2C+Molise%2C+Italy®ionId=6123603&latLong=41.596043%2C14.233161&adults=2&startDate=2026-05-27&d1=2026-05-27&endDate=2026-05-30&d2=2026-05-30&lodging=COTTAGE) Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Isernia%2C+Molise%2C+Italy®ionId=6123603&latLong=41.596043%2C14.233161&adults=2&startDate=2026-05-27&d1=2026-05-27&endDate=2026-05-30&d2=2026-05-30&lodging=CABIN) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FIsernia-Private-Holiday-Homes.d6123603-aaPrivateHolidayHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FIsernia-Private-Holiday-Homes.d6123603-aaPrivateHolidayHomes.Travel-Guide-Accommodation) ## Top Isernia Hotel Reviews ![Hotel Tiffany's](https://images.trvl-media.com/lodging/8000000/7180000/7179500/7179473/84737001_y.jpg) ### Hotel Tiffany's 10/10 Excellent "We had a great stay. Staff were welcoming and the room was clean and bright." [](https://expedia.co.uk/Roccaraso-Hotels-Hotel-Tiffanys.h7179473.Hotel-Information) ![Hotel Villa Danilo](https://images.trvl-media.com/lodging/23000000/22350000/22348300/22348293/1af69b37_y.jpg) ### Hotel Villa Danilo 10/10 Excellent "All was very pleasant and the room was warm! " [](https://expedia.co.uk/Gamberale-Hotels-Hotel-Villa-Danilo.h22348293.Hotel-Information) ![5 Miglia Hotel & SPA](https://images.trvl-media.com/lodging/17000000/16710000/16704600/16704505/702cb441_y.jpg) ### 5 Miglia Hotel & SPA 6/10 Okay "We never got to the hotel because I had a bad fall on the morning we were due to travel and so we had to cancel the trip. I was very disappointed not to be able to travel but hopefully I will get there another time. " [](https://expedia.co.uk/Rivisondoli-Hotels-5-Miglia-Hotel-SPA.h16704505.Hotel-Information) ![Best Western Hotel Rocca](https://images.trvl-media.com/lodging/4000000/3980000/3974100/3974048/118b47f4_y.jpg) ### Best Western Hotel Rocca 8/10 Good "Had a wonderful dinner. Shower was a bit small and the safe didn’t work but the staff were very helpful and nice " [](https://expedia.co.uk/Cassino-Hotels-Best-Western-Hotel-Rocca.h3974048.Hotel-Information) ![Hotel La Pace](https://images.trvl-media.com/lodging/19000000/18580000/18580000/18579979/abf303cf_y.jpg) ### Hotel La Pace 10/10 Excellent "We would stay here again." [](https://expedia.co.uk/Cassino-Hotels-Hotel-La-Pace.h18579979.Hotel-Information) ![Hotel Il Tiglio](https://images.trvl-media.com/lodging/4000000/3500000/3495100/3495089/f8dbec4a_y.jpg) ### Hotel Il Tiglio 10/10 Excellent "Mario was fantastic, personable, friendly, and took care of me at check in, booked a restaurant, etc..." [](https://expedia.co.uk/Castel-Di-Sangro-Hotels-Il-Tiglio-Hotel.h3495089.Hotel-Information) ## Find out more about Isernia ## Isernia Holiday Homes information | Number of reviews | | | ----------------- | ---------------- | | Accommodation | 62 Holiday Homes | | Lowest Price | £53 | | Highest Price | £597 | ## Explore a world of travel with Expedia - More ways to book - [Book Holiday Homes in Isernia on Expedia.it ](https://www.expedia.it/Isernia-Case-Vacanze-Private.d6123603-aaCaseVacanzePrivate.Guida-Viaggi-Alloggi)