Title: South Central Houston Travel Guide: Best of South Central Houston, Houston Travel 2026 | Expedia.co.uk [Hotels in South Central Houston](https://expedia.co.uk/South-Central-Houston-Houston-Hotels.0-n553248635976476176-0.Travel-Guide-Filter-Hotels)[Flights to Houston](https://expedia.co.uk/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.co.uk/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[South Central Houston Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-Central-Houston.d553248635976476176.Car-Hire-Guide)[South Central Houston Holidays](https://expedia.co.uk/South-Central-Houston.d553248635976476176.Holidays-City-Breaks) # South Central Houston Travel Guide ## Houston ![TMC](https://images.trvl-media.com/place/1503/58fd4720-60ea-4071-96b7-0d260c453508.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Taken from the back parking garage. ](https://images.trvl-media.com/place/1503/c78fddf6-c308-473d-b348-f8218b064137.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Taken along bike trail.](https://images.trvl-media.com/place/1503/a12ec45d-6ec7-489a-b481-8042a607dcfa.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Random structure in the museum district. ](https://images.trvl-media.com/place/1503/c2fa5b78-23a5-4fe5-b734-bea4da710c3b.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Another beautiful day in Houston.](https://images.trvl-media.com/place/1503/afb972ac-3993-4d8a-9604-7c2419ec0a38.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit South Central Houston Things to do Hotels Where to stay [Houston travel guide](https://expedia.co.uk/Houston.dx178265) --- ### Popular places to visit ![Rice University in Houston, Texas](https://images.trvl-media.com/place/501268/a41362fa-e6d4-492a-b448-4229167d03cd.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Rice University Enjoy the student vibe when you visit Rice University during your travels in Houston. Experience the area's lively festivals and fascinating museums. [](https://expedia.co.uk/Rice-University-South-Central-Houston.d501268.Attraction) ![Houston Zoo](https://images.trvl-media.com/place/6082223/4aa2a7c3-abd4-427b-9029-5d992410e1c3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Zoo 4.5/5(3 reviews) Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo. [](https://expedia.co.uk/Houston-Zoo-Southeast-Houston.d6082223.Attraction) ![Overcast view of the campus of University of Houston](https://images.trvl-media.com/place/501270/408ddf29-422d-4d68-b78b-92cf2e736df0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### University of Houston 4/5(1 review) Take a campus tour or just explore the area of University of Houston during your travels in Houston. Experience the great live music and lively festivals in this vibrant area. [](https://expedia.co.uk/University-Of-Houston-Houston.d501270.Attraction) ![The most happening place for toddlers in houston](https://images.trvl-media.com/place/1503/96c11d98-39b2-41f9-b570-bdc68afb4888.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Children's Museum of Houston 5/5(1 review) You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's acclaimed art galleries and great live music. [](https://expedia.co.uk/Childrens-Museum-Of-Houston-Houston.d6082211.Attraction) ![Houston Natural Science Museum featuring heritage elements and interior views](https://images.trvl-media.com/place/501256/4e455af8-0f6d-48a6-81ba-874182e2abef.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Natural Science Museum 5/5(5 reviews) You can spend time browsing the exhibits at Houston Natural Science Museum during your trip to Houston. Experience the area's great live music and acclaimed theatre scene. [](https://expedia.co.uk/Houston-Natural-Science-Museum-Houston.d501256.Attraction) ![Medical business district in Houston, TX](https://images.trvl-media.com/place/553248635389802729/c571dc10-dfbf-4d76-b73d-945d319a78ce.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Methodist Hospital If Houston Methodist Hospital is what brings you to town, hopefully you'll have a chance to explore more of Houston. [](https://expedia.co.uk/Houston-Methodist-Hospital-Houston.d553248635389802729.Attraction) ### Things to do ![Astroville Tunnel Tour of Downtown Houston](https://mediaim.expedia.com/localexpert/1358845/93d97319-081a-4fec-9e57-9de4737dfee7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Astroville Tunnel Tour of Downtown Houston (Air-Conditioned) £19 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/astroville-tunnel-tour-of-downtown-houston-air-conditioned.a1358845.activity-details) ![Houston: Sloomoo Institute Entry Ticket](https://mediaim.expedia.com/localexpert/48181877/0194cadc-0356-4ecd-a787-6fed90663fc8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston: Sloomoo Institute Entry Ticket £24 per adult [](https://expedia.co.uk/things-to-do/houston-sloomoo-institute-entry-ticket.a48181877.activity-details) ![Houston Museum of Natural Science: Cockrell Butterfly Center](https://mediaim.expedia.com/localexpert/44625315/13581a0d-ea47-46d7-8fcf-d3fc7aa4909c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Museum of Natural Science: Butterfly Center Ticket £11 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/houston-museum-of-natural-science-butterfly-center-ticket.a44625315.activity-details) ![Houston: Houston Botanic Garden Entry Ticket](https://mediaim.expedia.com/localexpert/46150646/bfc34474-c86f-4151-a485-5cc63efe2aab.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston: Houston Botanic Garden Entry Ticket £9 per adult **80%** of travellers recommend [](https://expedia.co.uk/things-to-do/houston-houston-botanic-garden-entry-ticket.a46150646.activity-details) ![Houston: Museum of Natural Science General Admission Ticket](https://mediaim.expedia.com/localexpert/44624726/7df2f7a9-1343-48ce-acab-88df62f142d4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Museum of Natural Science General Admission Ticket £19 per adult **98%** of travellers recommend [](https://expedia.co.uk/things-to-do/houston-museum-of-natural-science-general-admission-ticket.a44624726.activity-details) ![Houston: Holocaust Museum Houston Entry Ticket](https://mediaim.expedia.com/localexpert/47985204/cc6c178c-7c2f-47f0-8536-736f4d600e99.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston: Holocaust Museum Houston Entry Ticket £16 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/houston-holocaust-museum-houston-entry-ticket.a47985204.activity-details) [See all activities in Houston](https://expedia.co.uk/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities) --- ## Top hotels in South Central Houston ![Hotel Zaza Houston Museum District](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/0f950f88_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Zaza Houston Museum District 5701 Main Street Houston TX £237 3 Apr - 4 Apr includes taxes & fees Stay at this luxury aparthotel in Houston. Enjoy free Wi-Fi, a full-service spa and a rooftop terrace. Our guests praise the helpful staff in their reviews. ... 9/10 Wonderful! (1,926 reviews) Great vibe Reviewed on 22 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=03%2F04%2F2026&endDate=04%2F04%2F2026&selected=3306&PinnedHotelID=3306&HadPinnedHotel=true®ionId=553248635976476176) ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/77443f8e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Houston Plaza/Medical Center 6633 Travis St Houston TX £74 5 Apr - 6 Apr includes taxes & fees Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ... 8.4/10 Very Good! (1,865 reviews) Extremely noisy. Starting around 6:00AM there was constant noise. Carts rolling, walkie talkies , loud talking in the halls. Did not get a good night's sleep. Reviewed on 23 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=25188&PinnedHotelID=25188&HadPinnedHotel=true®ionId=553248635976476176) ![Downtowner Inns - Houston Downtown](https://images.trvl-media.com/lodging/118000000/117470000/117463300/117463205/e139024d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Downtowner Inns - Houston Downtown 2510 Hamilton St Houston TX £77 5 Apr - 6 Apr includes taxes & fees Stay at this hotel in Houston. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Toyota Center and Daikin Park are located nearby. 8.2/10 Very Good! (86 reviews) Everything was great for me I’ll be staying there again ! Staff there are very friendly Reviewed on 24 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=117463205&PinnedHotelID=117463205&HadPinnedHotel=true®ionId=553248635976476176) ![InterContinental Houston by IHG](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/2ea79db9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### InterContinental Houston by IHG 6750 Main St Houston TX £161 29 Mar - 30 Mar includes taxes & fees Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ... 9.2/10 Wonderful! (1,008 reviews) This an excellent hotel. Great for shuttle to NRG Stadium. Had buffet breakfast and it was delicious and restaurant staff was very nice and attentive. Parking garage next to hotel. The elevator takes you directly into the lobby. Reviewed on 23 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=29%2F03%2F2026&endDate=30%2F03%2F2026&selected=23830866&PinnedHotelID=23830866&HadPinnedHotel=true®ionId=553248635976476176) ![The Westin Houston Medical Center/Museum District](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/a994a387_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Westin Houston Medical Center/Museum District 1709 DRYDEN ROAD Houston TX £184 5 Apr - 6 Apr includes taxes & fees Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ... 9.2/10 Wonderful! (1,130 reviews) Daniel who was the bartender on duty when we checked in could not have been nicer. Room was more than fine. Clean hotel. One thing that did bother us from a security standpoint: anyone without a key can access any floor in the hotel. This is a big security concern. Reviewed on 20 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=39618635&PinnedHotelID=39618635&HadPinnedHotel=true®ionId=553248635976476176) ![DoubleTree by Hilton Houston Medical Center Hotel & Suites](https://images.trvl-media.com/lodging/1000000/10000/6700/6636/w3830h2557x6y0-b53d88b4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### DoubleTree by Hilton Houston Medical Center Hotel & Suites 6800 Main Street Houston TX £93 12 Apr - 13 Apr includes taxes & fees Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff in ... 8.4/10 Very Good! (545 reviews) Breakfast was pricey Reviewed on 19 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=12%2F04%2F2026&endDate=13%2F04%2F2026&selected=6636&PinnedHotelID=6636&HadPinnedHotel=true®ionId=553248635976476176) [See all 1,036 properties in South Central Houston](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=25%2F03%2F2026&endDate=26%2F03%2F2026®ionId=553248635976476176) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check South Central Houston hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976476176&startDate=2026-03-24&endDate=2026-03-25)[24 Mar - 25 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976476176&startDate=2026-03-24&endDate=2026-03-25) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976476176&startDate=2026-03-25&endDate=2026-03-26)[25 Mar - 26 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976476176&startDate=2026-03-25&endDate=2026-03-26) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976476176&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026)[27 Mar - 29 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976476176&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976476176&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026)[3 Apr - 5 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976476176&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026) --- ### Other neighbourhoods around South Central Houston ![Historic area of Houston.](https://images.trvl-media.com/place/1503/8a1d6680-853c-4601-8634-3ddc57cd8b28.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Greater Third Ward If you're spending time in Greater Third Ward, check out sights like Barbara Jordan & Mickey Leland Archives or Fertitta Center and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station. [](https://expedia.co.uk/Houston-Greater-Third-Ward.dx553248635976008254) ![Phoenix midtown skyline with a Saguaro Cactus and other desert scenery in the foreground.](https://images.trvl-media.com/place/6282039/f3a43cb9-8929-48c1-b277-aa868fe68431.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Midtown Midtown is well liked for its restaurants and live music. If you're hoping to get in some sightseeing, Houston Fire Museum and Midtown Arts and Theater Center Houston are top spots, and you can jump on the metro at McGowen Station or Ensemble/HCC Station to get around. [](https://expedia.co.uk/Houston-Midtown.dx6282039) ![Houston_EastDowntownHouston_6004016_9](https://images.trvl-media.com/place/6004016/c3f22058-7cd4-4678-81b9-53d4bbf939ff.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### East Downtown Houston 1/5(1 area review) The restaurants and live music are just a few things visitors like about East Downtown Houston. Shell Energy Stadium and Giant Beatles Statues are worthwhile spots to check out, and you can hop on the metro at Leeland/Third Ward Station or EaDo/Stadium Station to get around the larger area. [](https://expedia.co.uk/Houston-East-Downtown-Houston.dx6004016) ![TMC](https://images.trvl-media.com/place/1503/58fd4720-60ea-4071-96b7-0d260c453508.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Museum District Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city. [](https://expedia.co.uk/Houston-Houston-Museum-District.dx6164045) ![Taken from the parking garage. #UrbanJungle](https://images.trvl-media.com/place/1503/584a0ee8-b413-46fb-ad95-8f02fd4ce2b2.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Houston Central Business District If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station. [](https://expedia.co.uk/Houston-Houston-Central-Business-District.dx553248635976473213) ![Discovery Green showing city views, modern architecture and a high-rise building](https://images.trvl-media.com/place/6082195/fa70078e-ab30-43a5-aa06-e3a763da2444.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown Houston 4/5(25 area reviews) Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams. [](https://expedia.co.uk/Houston-Downtown-Houston.dx800037) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # South Central Houston Travel Guide ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app