South Central Houston Travel Guide

Houston

A water feature with multiple tiers and a circular viewing platform at the top.
A city skyline at night with illuminated skyscrapers and a large brick plaza in the foreground.
A train on tracks with graffiti on a nearby building.
A park with a gazebo, a fountain, and tall buildings in the background.
A water feature with a cascading waterfall, a grassy hill, and a tall building in the background.

Stay near popular South Central Houston attractions

A large historic building with a red roof and arched windows, surrounded by a well-maintained garden and a clear blue sky.

Rice University

8.6/10 (1,772 reviews)
Walk around the campus of Rice University, a top university in Houston. Experience the area's acclaimed theatre scene and lively festivals.
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Things to do

Picture 3 for Activity Houston: Space Center Houston Admission Ticket

Houston: Space Center Houston Admission Ticket

£22
per adult
92% of travellers recommend
Houston: Space Center Houston Admission Ticket
Houston: Guided City Tour by an Open-Top Double Decker Bus

Houston: Guided City Tour by an Open-Top Double Decker Bus

£30
per adult
98% of travellers recommend
Houston: Guided City Tour by an Open-Top Double Decker Bus
HOP ON- HOP OFF

Houston's Official City & Mural Tour!

£30
per adult
88% of travellers recommend
Houston's Official City & Mural Tour!
Houston: Sloomoo Institute Entry Ticket

Houston: Sloomoo Institute Entry Ticket

£24
per adult
Houston: Sloomoo Institute Entry Ticket
Discover Houston Self Guided City Tour

Discover Houston: A Self-Guided City Tour

£1
per adult
100% of travellers recommend
Discover Houston: A Self-Guided City Tour
Artechouse Houston Ticket

Artechouse Houston Ticket

£23
per adult
Artechouse Houston Ticket
See all activities in Houston

Top hotels in South Central Houston

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
The price is £215 per night from 16 Aug to 17 Aug
£215
16 Aug - 17 Aug
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular ...
Hotel Zaza Houston Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is £78 per night from 30 Aug to 31 Aug
£78
30 Aug - 31 Aug
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ...
Hilton Houston Plaza/Medical Center
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
The price is £147 per night from 8 Aug to 9 Aug
£147
8 Aug - 9 Aug
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ...
9.4/10 Exceptional! (1,012 reviews)
"Ok"

Reviewed on 7 Aug 2026

InterContinental Houston by IHG
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
The price is £133 per night from 6 Sept to 7 Sept
£133
6 Sept - 7 Sept
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ...
The Westin Houston Medical Center/Museum District
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

4 out of 5
6580 Fannin Street Houston TX
The price is £148 per night from 29 Aug to 30 Aug
£148
29 Aug - 30 Aug
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free local area shuttle and room service. Our guests praise the helpful staff ...
9/10 Wonderful! (1,009 reviews)
"Customer service is great at this hotel!"

Reviewed on 7 Aug 2026

Houston Marriott Medical Center/Museum District
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
The price is £106 per night from 21 Aug to 22 Aug
£106
21 Aug - 22 Aug
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff in ...
8.4/10 Very good! (654 reviews)
"Very nice hotel to stay in and had warm cookies which was a nice treat ."

Reviewed on 5 Aug 2026

DoubleTree by Hilton Houston Medical Center Hotel & Suites
See all 1,257 properties in South Central Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.
A cityscape with modern skyscrapers and a park with trees and people.

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.

A large, modern shopping mall with a glass ceiling and multiple levels.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

A cityscape with tall buildings, including a prominent one with 'Texas Children's Hospital' on it, under a partly cloudy sky.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

An art gallery with a minimalist design, featuring a central bench and large abstract paintings on the walls.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or The Chapel of St. Basil while you're exploring the area.

South Central Houston Travel Guide

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