A brick-paved street lined with historic buildings and a yellow fire hydrant.

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Check prices for these dates

Tonight
26 Sept - 27 Sept
Tomorrow
27 Sept - 28 Sept
Next weekend
2 Oct - 4 Oct
In two weeks
9 Oct - 11 Oct

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Our top choices for Historic Main Street hotels

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.
A spacious lobby with a large sectional sofa, a reception desk, and a bar area.
A gym with treadmills, stationary bikes, and a weight machine.
A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

1. Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
1.1 mi from Historic Main Street
United States
Robert
£119
includes taxes & fees
1 Oct - 2 Oct
Drury Plaza Hotel St. Louis St. Charles
A modern kitchen with a central island, breakfast bar, and various appliances.
A hotel room with a large bed, a desk, a chair, and a window with a view.
A modern hotel reception area with a receptionist desk, a large welcome sign, and a view of the cityscape through the glass doors.
An indoor swimming pool with blue walls, a tiled floor, and lounge chairs.

2. Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
0.9 mi from Historic Main Street
United States
Daniel
£104
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn & Suites St. Charles Old Town Area
A spacious indoor lobby with multiple seating areas, including round tables and sofas, and a central water feature.
A multi-story hotel with a central courtyard, a parking lot, and a green-roofed building.
A hotel room with a sofa, armchairs, a coffee table, a desk, and a large window with curtains.
A grand staircase with a wooden railing leading to a lower level, surrounded by potted plants and a patterned carpet.

3. Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
1.3 mi from Historic Main Street
United States
Anthony
£120
includes taxes & fees
11 Oct - 12 Oct
Embassy Suites by Hilton St. Louis St. Charles
A large hotel with a prominent tower and multiple parking areas.
A spacious lobby with a patterned carpet, a reception desk, and a seating area with a sofa and chairs.
A crowded indoor space with a chandelier, brick walls, and tables where people are seated and standing.
A bar area with a long counter, multiple screens, and seating.

4. Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
1.8 mi from Historic Main Street
United States
Nicole
£96
includes taxes & fees
19 Oct - 20 Oct
Hollywood Casino & Hotel St. Louis
A modern hotel with a prominent Hilton logo, multiple floors, and a well-lit entrance.
A modern lounge area with seating arrangements, tables, and hanging pendant lights.
A modern lounge area with sofas, tables, and chairs, featuring a mix of seating arrangements and a central coffee station.
A self-service beverage station with a refrigerated display and a microwave.

5. Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
1.3 mi from Historic Main Street
United States
Meridith
£121
includes taxes & fees
4 Oct - 5 Oct
Tru by Hilton St. Charles St. Louis, MO
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A bakery display case with various pastries and cakes.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
0.9 mi from Historic Main Street
United States
Melissa
£145
includes taxes & fees
12 Oct - 13 Oct
Ameristar Casino Resort and Spa
A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.
A spacious lobby with a reception desk, a seating area with a sofa, a vending machine, and a wall-mounted clock.
A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.
A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.

7. Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
1 mi from Historic Main Street
United States
Bryan
£76
includes taxes & fees
18 Oct - 19 Oct
Comfort Suites St Charles - St Louis
A spacious lobby with a modern design, featuring a large seating area with sofas and chairs, a patterned carpet, and a view of the outside through large windows.
A modern kitchen with white cabinets, a long countertop, and overhead lighting.

8. Elimwood Hotel, a Ramada by Wyndham

Elimwood Hotel, a Ramada by Wyndham
1.9 mi from Historic Main Street
United States
Christina
£66
includes taxes & fees
1 Oct - 2 Oct
Elimwood Hotel, a Ramada by Wyndham
A restaurant with a long wooden table, cushioned seating, and decorative lanterns.
A compact kitchen with dark wooden cabinets, a built-in microwave, and a stainless steel refrigerator.
A hotel room with a kitchenette, a sofa, a desk, and a large window with curtains.
A hotel room with two beds, a nightstand with a lamp, a framed picture on the wall, and a patterned carpet.

9. Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG
1.8 mi from Historic Main Street
United States
Bryan
£96
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn St. Louis Arpt West-Earth City by IHG
A spacious lobby with a reception desk, seating area, and a fireplace.
A living room with a beige sofa, a wooden coffee table, a patterned rug, a potted plant, and two framed pictures on the wall.
A dining area with round tables and white chairs, a kitchen counter with appliances, and a framed picture on the wall.
A lobby with a fireplace, several potted plants, a television, and a sofa.

10. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
1 mi from Historic Main Street
United States
Tom
£67
includes taxes & fees
27 Sept - 28 Sept
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.
A hotel room with a bed, a desk, a television, and a lamp.
A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.
A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

11. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
6.6 mi from Historic Main Street
United States
Monica
£80
includes taxes & fees
4 Oct - 5 Oct
Pear Tree Inn St. Louis Airport
A spacious lobby with a central round table, two sofas, and a chandelier.
A buffet setup with various food items and a decorative vase of flowers.
A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.
An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

12. Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
9.8 mi from Historic Main Street
United States
Cassandra
£114
includes taxes & fees
25 Oct - 26 Oct
Drury Plaza Hotel St. Louis Chesterfield
A modern kitchen with a bar area, wooden cabinets, and pendant lighting.
A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.
A modern hotel entrance with a glass canopy, large windows, and a brick facade.
A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

13. Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
9.9 mi from Historic Main Street
United States
Chelsea
£113
includes taxes & fees
29 Sept - 30 Sept
Hyatt Place St. Louis/Chesterfield
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.
A hotel room with a desk, chair, TV, and a framed picture on the wall.
A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.
A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

14. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
6.6 mi from Historic Main Street
United States
Tessa
£83
includes taxes & fees
27 Sept - 28 Sept
Wingate by Wyndham St. Louis Airport
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.
A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.
A modern lobby with blue seating, a reception desk, and large windows.
A modern dining area with a long table, multiple chairs, and a unique chandelier.

15. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
7.5 mi from Historic Main Street
United States
Maxine
£102
includes taxes & fees
3 Oct - 4 Oct
Hyatt Select St. Louis Airport
A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.
A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.
A pool area with two hot tubs, seating, and a view of the outdoors.
A hotel reception area with a counter, seating, and a staircase.

16. Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
7 mi from Historic Main Street
United States
Hope
£102
includes taxes & fees
4 Oct - 5 Oct
Drury Inn & Suites St. Louis Airport
An outdoor patio with a built-in grill, seating area, and stone walls.
A multi-story hotel with a parking lot in front.
An indoor swimming pool with clear glass walls, sunlit seating area, and lifeguard station.
A spacious lounge area with a stone fireplace, comfortable seating, and a large TV screen.

17. Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
9.4 mi from Historic Main Street
United States
Brandon
£167
includes taxes & fees
3 Oct - 4 Oct
Residence Inn by Marriott St. Louis Chesterfield
An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.
A dining area with tables and chairs, a blue sofa, and a patterned carpet.
A hotel lobby with a reception desk, seating area, and a view of the parking lot.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

18. Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport
7.3 mi from Historic Main Street
United States
Leia
£116
includes taxes & fees
8 Oct - 9 Oct
Hampton Inn By Hilton St Louis Airport
A modern lounge area with a stone fireplace, a blue sofa, and a small table.
A modern lobby with a blue sofa, a reception desk, and a snack bar.
A Fairfield Inn & Suites Marriott hotel entrance with a modern design, featuring a brick facade, a covered entrance area, and a clear sky in the background.
An indoor swimming pool with lounge chairs and tables, large windows, and a clock on the wall.

19. Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport
5.9 mi from Historic Main Street
United States
Deoshae
£115
includes taxes & fees
4 Oct - 5 Oct
Fairfield Inn & Suites St Louis Westport
An outdoor patio area with wicker furniture, a stone fire pit, and a building in the background.
A modern bar area with wooden furniture, a counter with a menu, and a seating area with tables and chairs.
A Courtyard by Marriott hotel with a modern design, multiple floors, and a flat roof.

20. Courtyard by Marriott St. Louis St. Peters

Courtyard by Marriott St. Louis St. Peters
5.3 mi from Historic Main Street
United States
Krischel
£109
includes taxes & fees
4 Oct - 5 Oct
Courtyard by Marriott St. Louis St. Peters
View all properties

Compare popular hotels close to Historic Main Street

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.
Drury Plaza Hotel St. Louis St. Charles
9.6
Exceptional
1,001 reviews
View
A modern kitchen with a central island, breakfast bar, and various appliances.
Hampton Inn & Suites St. Charles Old Town Area
9.0
Wonderful
739 reviews
View
A spacious indoor lobby with multiple seating areas, including round tables and sofas, and a central water feature.
Embassy Suites by Hilton St. Louis St. Charles
8.8
Excellent
1,000 reviews
View
A large hotel with a prominent tower and multiple parking areas.
Hollywood Casino & Hotel St. Louis
8.6
Excellent
2,240 reviews
View
A modern hotel with a prominent Hilton logo, multiple floors, and a well-lit entrance.
Tru by Hilton St. Charles St. Louis, MO
8.6
Excellent
876 reviews
View

Top Historic Main Street Hotel Reviews

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent
"Staff was welcoming and very helpful with a situation that occurred with our booking!"
Kathy 3-night trip
Posted 19 hours ago
Country Inn & Suites by Radisson, St. Charles Historic District
The Rustic Revival | Charming 2BR Retreat

The Rustic Revival | Charming 2BR Retreat

10/10 Excellent
"The Host ensured our needs were taken care. Perfect location!"
Phyllis N. 4-night trip
Posted 3 weeks ago
The Rustic Revival | Charming 2BR Retreat
Driftwood Den | Boho 2BR | Dog-Friendly

Driftwood Den | Boho 2BR | Dog-Friendly

10/10 Excellent
"Clean, easy parking, easy egress and ingress"
Rachel M. 5-night trip
Posted 1 month ago
Driftwood Den | Boho 2BR | Dog-Friendly
Stylish 2BR Retreat - Concrete & Canopy

Stylish 2BR Retreat - Concrete & Canopy

10/10 Excellent
"This is our new favorite property in St. Charles. Between the location, size of the space and the designated parking spot, we will definitely be staying here again!"
Billi G. 2-night trip
Posted 1 month ago
Stylish 2BR Retreat - Concrete & Canopy
The Foundry Flat | Industrial-Inspired 2-Bedroom

The Foundry Flat | Industrial-Inspired 2-Bedroom

10/10 Excellent
"Everything was exactly as described. St. Charles is an awesome place!"
Michael 2-night trip
Posted 1 month ago
The Foundry Flat | Industrial-Inspired 2-Bedroom
The Global Getaway | World-Inspired 2-Bedroom Stay

The Global Getaway | World-Inspired 2-Bedroom Stay

10/10 Excellent
"Perfect location to Main Street.Hosts were easy to communicate with.No issues with the unit"
Tony M. 4-night trip
Posted 1 month ago
The Global Getaway | World-Inspired 2-Bedroom Stay
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

10/10 Excellent
"The home was very inviting! All of the hosts extra touches so appreciated (coffee pods, snacks, etc). Beds were comfortable and all necessities were available. A wonderful stay! We will definitely return."
Cathilynne F. 3-night trip
Posted 2 months ago
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
The St. Charles Guest House, lovely historic home, fun for families and groups

The St. Charles Guest House, lovely historic home, fun for families and groups

10/10 Excellent
"The location of the house was fabulous. You are literally steps from the Main Street of historic St. Charles. Walking distance to several restaurants, shops, dessert stops and coffee shops. We also enjoyed the greater St Charles area and it was a quick drive into St Louis.The house is well stocked (could use some more towels) with a nice kitchen area. We enjoyed the game room and living room reading corner. Love being able to come home with clean clothes so appreciate the washer and dryer.We hit St Charles during a heat wave and the house really struggled to get cooler than 75 degrees. We also didn’t realize how many steps there were throughout the house. The staircase upstairs is fairly steep. To get to the master bedroom one must maneuver several steps and climb from the steps into the bed. We were fine just wanted to give others the heads up if accessibility was an issue.We truly enjoyed the St Charles area and hope to visit again soon!"
Erin T. 4-night trip
Posted 2 months ago
The St. Charles Guest House, lovely historic home, fun for families and groups
Hearth & Harvest | Historic St. Charles 2BR

Hearth & Harvest | Historic St. Charles 2BR

10/10 Excellent
"This is one place that I would book again and again. Yes, however, the one-bedroom is on the main street, so there's outside noise, but I'm thankful to have a TV to drown out some of the chatter and music from outside. High ceilings great vibes."
George G. 2-night trip
Posted 2 months ago
Hearth & Harvest | Historic St. Charles 2BR

Other attractions near Historic Main Street

A person holding a guitar.
Photo by HA

Frontier Park

You can find out about the history of St. Charles with a stop at Frontier Park. Visit the shops and top-notch restaurants in this walkable area.
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A steel bridge over a calm river with lush greenery and trees in the background.

Katy Trail

9.0/10 (158 reviews)
You can take time to visit Katy Trail during your travels to St. Charles. Experience the great live music and acclaimed theatre scene in this family-friendly area.
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First Missouri State Capitol Historic Site

8.2/10 (25 reviews)
You can learn about the history of St. Charles with a stop at First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theatre scene in this family-friendly area.
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Missouri Artists on Main

You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Visit the shops and top-notch restaurants in this family-friendly area.
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Lewis & Clark Boathouse and Nature Center

8.8/10 (113 reviews)
You can spend time studying the exhibits at Lewis & Clark Boathouse and Nature Center during your trip to St. Charles. Experience the great live music and acclaimed theatre scene in this family-friendly area.
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Frenchtown Heritage Museum

You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Visit the shops and top-notch restaurants in this family-friendly area.
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Lindenwood University

8.6/10 (183 reviews)
Enjoy the student vibe at Lindenwood University during your stay in St. Charles. Experience the acclaimed theatre scene and great live music in this family-friendly area.
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St Charles Convention Center

8.4/10 (223 reviews)
After visiting St Charles Convention Center, make a plan to see the other sights and activities in St. Charles. Discover the top-notch restaurants and great live music in this family-friendly area.
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Frequently asked questions

What's the area like around Historic Main Street?
Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 104 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Historic Main Street?
Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Another good option is Country Inn & Suites by Radisson, St. Charles Historic District, located just 0.6 mi (1 km) away.
How many hotels are there near Historic Main Street?
Expedia has 104 hotels and other accommodation options within a mile from Historic Main Street.
If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to get the best options available near Historic Main Street.
What can I see and do near Historic Main Street?
Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main and Historic Aircraft Restoration Museum, you'll experience some of the local culture.