The Best Hotels Closest to Historic Main Street in St. Louis - 2026 Updated Prices

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Our top choices for Historic Main Street hotels

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

1. Drury Plaza Hotel St. Louis St. Charles

1.1 mi from Historic Main Street

Madhusudhana Rao

includes taxes & fees

22 Nov - 23 Nov

A brick building with a sign reading "Country Inn & Suites."

2. Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District, 0.6 mi from Historic Main Street

Stewart

includes taxes & fees

6 Dec - 7 Dec

A modern kitchen with a central island, breakfast bar, and various appliances.

3. Hampton Inn & Suites St. Charles Old Town Area

0.9 mi from Historic Main Street

Sara

includes taxes & fees

29 Nov - 30 Nov

A multi-level hotel lobby with numerous seating areas, a central water feature, and a variety of plants.

4. Embassy Suites by Hilton St. Louis St. Charles

1.3 mi from Historic Main Street

Elyse

includes taxes & fees

22 Nov - 23 Nov

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

5. Ameristar Casino Resort and Spa

0.9 mi from Historic Main Street

Carter

includes taxes & fees

25 Nov - 26 Nov

A bar area with a long counter, multiple screens, and seating.

6. Hollywood Casino & Hotel St. Louis

1.8 mi from Historic Main Street

Shayla

includes taxes & fees

6 Dec - 7 Dec

7. Tru by Hilton St. Charles St. Louis, MO

1.3 mi from Historic Main Street

Alissa

includes taxes & fees

22 Nov - 23 Nov

A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

8. Comfort Suites St Charles - St Louis

1 mi from Historic Main Street

Shawna

includes taxes & fees

6 Dec - 7 Dec

A spacious living room with a large sectional sofa, a coffee table, and a fireplace. There is a television mounted on the wall and a chandelier hanging from the ceiling.

9. Best Western Plus The Charles Hotel

1 mi from Historic Main Street

Steven

includes taxes & fees

12 Nov - 13 Nov

A spacious bar area with a long wooden counter, multiple bar stools, and a variety of bar tools.

10. Holiday Inn St. Louis Arpt West-Earth City by IHG

1.8 mi from Historic Main Street

marilyn

includes taxes & fees

29 Nov - 30 Nov

11. Elimwood Hotel, a Ramada by Wyndham

1.9 mi from Historic Main Street

Lucas

includes taxes & fees

17 Nov - 18 Nov

A spacious lobby with a reception desk, seating area, and a fireplace.

12. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1 mi from Historic Main Street

Gonzalo

includes taxes & fees

14 Nov - 15 Nov

A spacious lobby with a central round table, two sofas, and a chandelier.

13. Drury Plaza Hotel St. Louis Chesterfield

9.8 mi from Historic Main Street

messia

includes taxes & fees

19 Nov - 20 Nov

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

14. Pear Tree Inn St. Louis Airport

6.6 mi from Historic Main Street

Rebecca

includes taxes & fees

19 Nov - 20 Nov

An outdoor patio with a built-in grill, seating area, and stone walls.

15. Residence Inn by Marriott St. Louis Chesterfield

9.4 mi from Historic Main Street

Roberta

includes taxes & fees

24 Nov - 25 Nov

A spacious lobby with a high ceiling, a dining area, and a seating area with sofas and a coffee table.

16. Drury Inn & Suites St. Louis St. Peters

7.5 mi from Historic Main Street

Michael

includes taxes & fees

22 Nov - 23 Nov

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

17. Wingate by Wyndham St. Louis Airport

6.6 mi from Historic Main Street

Cindy

includes taxes & fees

18 Nov - 19 Nov

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.

18. Holiday Inn Express & Suites St Peters by IHG

9.8 mi from Historic Main Street

Roxanne

includes taxes & fees

15 Nov - 16 Nov

A modern hotel with a prominent entrance, a landscaped courtyard, and a well-lit facade.

19. AC Hotel by Marriott St. Louis Chesterfield

9.5 mi from Historic Main Street

Richard

includes taxes & fees

24 Nov - 25 Nov

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

20. Hyatt Select St. Louis Airport

7.5 mi from Historic Main Street

Thadora

includes taxes & fees

13 Nov - 14 Nov

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Compare popular hotels close to Historic Main Street

Property	Property class	Guest rating
Drury Plaza Hotel St. Louis St. Charles	3.0 star property	9.6 Exceptional 1,001 reviews	View
Country Inn & Suites by Radisson, St. Charles Historic District	2.5 star property	9.4 Exceptional 1,109 reviews	View
Hampton Inn & Suites St. Charles Old Town Area	2.5 star property	9.0 Wonderful 762 reviews	View
Embassy Suites by Hilton St. Louis St. Charles	3.5 star property	8.8 Excellent 1,002 reviews	View
Ameristar Casino Resort and Spa	4.5 star property	8.8 Excellent 1,088 reviews	View

Hotels recommended for families near Historic Main Street

Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District

includes taxes & fees

6 Dec - 7 Dec

Top Historic Main Street Hotel Reviews

Ameristar Casino Resort and Spa

8/10 Good

"We were here for a wedding. Our room was very nice but my son’s bathroom was disgusting and not clean, they had to switch rooms and the only compensation they gave them was a food voucher. Not acceptable with blood and vomit not cleaned from previous guest. We expected more for this caliber of hotel."

Main Street 2BR - Walk to Dining & Riverfront

8/10 Good

"Great location for walking Main Street. The place was clean however, I don’t believe the floors had been mopped before my arrival. The second day I had to pick something off the floor using a paper towel and it was very dirty. More like I had already stayed there more than a week. Also, if you are traveling with a dog, there isn’t anywhere close for your dogs to find grass. There is Main Street, of course, but for dogs to do their business, the best place is on the Katy Trail. That’s great during the day but for evening walks before bed not convenient. Also be aware if staying through Friday or Saturday nights, it gets very loud outside due to Main Street restaurants and bars staying open until 1:30 a.m. This property is directly across from Tony’s and their bar and the Q, are the late night spots. If you’re planning to join in on the fun, no problem but if you’re trying to sleep, not good. The unit has sound machines in their bedrooms which might work for some but the quality is not the best. Overall, the place was nice and up to date. The cleanliness I would have given 5-stars but the dirty floors lowered to 4-stars."

Historic Main 2BR | Free Parking | Brick & Beam

8/10 Good

"The property was very clean. I would have given it five stars however, if you are expecting a restful night this is not the place. We weren’t familiar with the area, and didn’t realize we were staying across the street from a bar with a roof top open until 1am. The walls of this place are very thin, and you will hear every drunken yell. To include some one yelling at pedestrians as they walked by “HEY pick a number between 1 and 8!” Over and over and over. It was about 3 am before things quieted down. There were cars revving their engines just outside the window until 2 am as well. Like I stated before the room is very clean and nice just not the best location if you are expecting a restful getaway."

Other attractions near Historic Main Street

Frontier Park

You can find out about the history of St. Charles with a stop at Frontier Park. Visit the shops and top-notch restaurants in this walkable area.

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Frequently asked questions

What's the area like around Historic Main Street?

Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 103 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay close to Historic Main Street?

Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Another good option is Country Inn & Suites by Radisson, St. Charles Historic District, located just 0.6 mi (1 km) away.

How many hotels are there near Historic Main Street?

Expedia has 103 hotels and other accommodation options within a mile from Historic Main Street.

If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to get the best options available near Historic Main Street.

What can I see and do near Historic Main Street?

Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main and Historic Aircraft Restoration Museum, you'll experience some of the local culture.

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Our top choices for Historic Main Street hotels

1. Drury Plaza Hotel St. Louis St. Charles

2. Country Inn & Suites by Radisson, St. Charles Historic District

3. Hampton Inn & Suites St. Charles Old Town Area

4. Embassy Suites by Hilton St. Louis St. Charles

5. Ameristar Casino Resort and Spa

6. Hollywood Casino & Hotel St. Louis

7. Tru by Hilton St. Charles St. Louis, MO

8. Comfort Suites St Charles - St Louis

9. Best Western Plus The Charles Hotel

10. Holiday Inn St. Louis Arpt West-Earth City by IHG

11. Elimwood Hotel, a Ramada by Wyndham

12. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

13. Drury Plaza Hotel St. Louis Chesterfield

14. Pear Tree Inn St. Louis Airport

15. Residence Inn by Marriott St. Louis Chesterfield

16. Drury Inn & Suites St. Louis St. Peters

17. Wingate by Wyndham St. Louis Airport

18. Holiday Inn Express & Suites St Peters by IHG

19. AC Hotel by Marriott St. Louis Chesterfield

20. Hyatt Select St. Louis Airport

Compare popular hotels close to Historic Main Street

Hotels recommended for families near Historic Main Street

Country Inn & Suites by Radisson, St. Charles Historic District

Top Historic Main Street Hotel Reviews

Ameristar Casino Resort and Spa

Other attractions near Historic Main Street

Frontier Park

Frequently asked questions