Title: Hotels in Greencastle, MO - Best Greencastle Hotels from £48 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Greencastle](https://expedia.co.uk/Greencastle-Holiday-Rentals.d553248634983462000.Travel-Guide-HolidayRentals)[Greencastle Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Greencastle.d553248634983462000.Car-Hire-Guide)[Greencastle Holidays](https://expedia.co.uk/Greencastle.d553248634983462000.Holidays-City-Breaks) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Greencastle, MO from £48 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Greencastle Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Greencastle%2C+Missouri%2C+United+States+of+America®ionId=553248634983462000&latLong=40.262523%2C-92.877981&adults=2&startDate=2025-10-23&d1=2025-10-23&endDate=2025-10-25&d2=2025-10-25&amenities=PETS) ## Check prices for these dates Tonight [9 Oct - 10 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983462000&startDate=2025-10-09&endDate=2025-10-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983462000&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983462000&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983462000&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Greencastle hotels and places to stay ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/093bb3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/f7bdd93b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/f3c5f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Kirksville Kirksville 6.6/10 (1001) "My wife got food poisoning from breakfast we would like a refund " £48 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/0cfe6b5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/33e2a913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/06554a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Studio Suite, 1 King Bed, Non Smoking | Jetted bathtub](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/b428c708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Kirksville University Area Kirksville 7.6/10 Good (888) "Friendly staff, clean rooms" £54 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/ebcfa50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/0822c1df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/8218b8bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Kirksville Kirksville 9.2/10 Wonderful (541) "Clean hotel with friendly staff. " £103 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information) ![Room, 2 Double Beds, Non Smoking | Pillow-top beds, desk, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/4afe2a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/fd2e50c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/9c660a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Kirksville-University Area Kirksville 9.0/10 Wonderful (110) "Clean room, quick check in, very friendly staff." £54 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/781fda5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/a8e8f4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/26642d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Kirksville - University Area by IHG Kirksville 9.2/10 Wonderful (491) "Good breakfast. Clean. " £107 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/2dd82658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/45e37c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/74b6e2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Down duvets, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/7d76c669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Kirksville Kirksville 7.6/10 Good (388) "Good place " £64 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/fa987a1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, free toiletries, towels](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/cf6ce139.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed | Desk, free cots/infant beds, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/b5263971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/9b5928a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Knights Inn Kirksville Kirksville 7.2/10 Good (248) "It was ok" £57 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-23&endDate=2025-10-24®ionId=553248634983462000&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FGreencastle-Hotels.d553248634983462000.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FGreencastle-Hotels.d553248634983462000.Travel-Guide-Hotels) ## Top Greencastle Hotel Reviews ![Super 8 by Wyndham Kirksville-University Area](//images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg) ### Super 8 by Wyndham Kirksville-University Area 10/10 Excellent "Nice " [](https://expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![New tiny home in an incredible private setting among all nature has to offer.](//images.trvl-media.com/lodging/118000000/117030000/117029100/117029091/2899d4ac_y.jpg) ### New tiny home in an incredible private setting among all nature has to offer. 10/10 Excellent "Loved this place! Can't wait to come back! " [](https://expedia.co.uk/Kirksville-Hotels-New-Tiny-Home-In-An-Incredible-Private-Setting-Among-All-Nature-Has-To-Offer.h117029091.Hotel-Information) ![Thousand Hills](//images.trvl-media.com/lodging/107000000/106800000/106792500/106792431/855824fb_y.jpg) ### Thousand Hills 10/10 Excellent "Beautiful views and cabins are decently spaced for privacy." [](https://expedia.co.uk/Kirksville-Hotels-Thousand-Hills.h106792431.Hotel-Information) ![Home in the Heart of Kirksville](//images.trvl-media.com/lodging/104000000/103100000/103097400/103097370/1c70daa1_y.jpg) ### Home in the Heart of Kirksville 10/10 Excellent "We were in town for a wedding and the house was perfect for us! It was comfortable and had everything we needed and more! We appreciated the early check-in and loved the homey feel location had. Will stay here again if we are in the area!! Thank you! " [](https://expedia.co.uk/Kirksville-Hotels-Home-In-The-Heart-Of-Kirksville.h103097370.Hotel-Information) ![Little Blue Cottage - Charming 1-bedroom cottage in Kirksville](//images.trvl-media.com/lodging/109000000/108400000/108390200/108390143/acd401ea_y.jpg) ### Little Blue Cottage - Charming 1-bedroom cottage in Kirksville 10/10 Excellent "A lot of old homes that are not well taken care of. " [](https://expedia.co.uk/Kirksville-Hotels-Little-Blue-Cottage-Charming-1-Bedroom-Cottage-In-Kirksville.h108390143.Hotel-Information) ![Base Camp Cottage](//images.trvl-media.com/lodging/112000000/111840000/111833600/111833563/aa1f0009_y.jpg) ### Base Camp Cottage 10/10 Excellent "This house was perfect for my family to stay in. Our family was having a reunion in Thousand Hills State Park and this was just a short drive away. I SO appreciated that there were a few little toys for my kids to play with. The house had everything we needed and was very clean. Would definitely recommend! " [](https://expedia.co.uk/Kirksville-Hotels-Base-Camp-Cottage.h111833563.Hotel-Information) ![Country Cabin In The Woods](//images.trvl-media.com/lodging/105000000/104310000/104308300/104308277/529c3996_y.jpg) ### Country Cabin In The Woods 10/10 Excellent "The cabin was a great get away from the town. Very remote and peaceful cabin. Very clean. Could have used some brighter lighting. It was difficult to play games at the kitchen table after sunset. Thank you!!!" [](https://expedia.co.uk/Kirksville-Hotels-Country-Cabin-In-The-Woods.h104308277.Hotel-Information) ![Queen's Quarters : 3 bedroom/ 1 bath Townhome, Centrally Located.](//images.trvl-media.com/lodging/115000000/114470000/114461200/114461156/a5beb5e9_y.jpg) ### Queen's Quarters : 3 bedroom/ 1 bath Townhome, Centrally Located. 10/10 Excellent "The perfect place for our needs. Right near town, with easy access to the restaurants and shops. " [](https://expedia.co.uk/Kirksville-Hotels-Queens-Quarters-3-Bedroom-1-Bath-Townhome.h114461156.Hotel-Information) ## More cheap stays in Greencastle ![Baymont by Wyndham Kirksville University Area](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/0cfe6b5f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Kirksville University Area 2702 South Franklin, Kirksville, MO £54 19 Oct - 20 Oct includes taxes & fees 7.6/10 Good! (887 reviews) [](https://expedia.co.uk/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information) ![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Kirksville-University Area 1101 Country Club Dr, Kirksville, MO £54 19 Oct - 20 Oct includes taxes & fees 9/10 Wonderful! (109 reviews) [](https://expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![Hampton Inn Kirksville](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Kirksville 2604 N. Baltimore Street, Kirksville, MO £103 19 Oct - 20 Oct includes taxes & fees 9/10 Wonderful! (541 reviews) [](https://expedia.co.uk/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information) ![Holiday Inn Express & Suites Kirksville - University Area by IHG](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Kirksville - University Area by IHG 2523 South Franklin St., Kirksville, MO £107 2 Nov - 3 Nov includes taxes & fees 9.2/10 Wonderful! (491 reviews) [](https://expedia.co.uk/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) ![Quality Inn Kirksville](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/2dd82658_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Kirksville 2209 N Baltimore St, Kirksville, MO £64 2 Nov - 3 Nov includes taxes & fees 7.4/10 Good! (388 reviews) [](https://expedia.co.uk/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information) ![Days Inn by Wyndham Kirksville](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Kirksville 3805 S Baltimore St, Kirksville, MO £48 13 Oct - 14 Oct includes taxes & fees 6.6/10 (1,005 reviews) [](https://expedia.co.uk/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) ## Frequently asked questions ### What's the best place for a stay in Greencastle? > [Super 8 by Wyndham Kirksville-University Area](https://www.expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information), located 17.4 mi (27.9 km) from the heart of Greencastle, is a top choice for your stay, based on our traveller data. Other good options for your visit to the area are [Days Inn by Wyndham Kirksville](https://www.expedia.co.uk/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) and [Baymont by Wyndham Kirksville University Area](https://www.expedia.co.uk/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information). See all available [top hotels](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983462000), or [vacation rentals in Greencastle](https://www.expedia.co.uk/Greencastle-Holiday-Rentals.d553248634983462000.Travel-Guide-HolidayRentals). ### What are some of the best holiday rentals that Greencastle has to offer? > [Country's Edge Retreat](https://www.expedia.co.uk/Greentop-Hotels-Countrys-Edge-Retreat.h120064921.Hotel-Information): This holiday home rental outside of Greencastle offers a patio, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a stovetop and a microwave, so that you can cook with friends or family. See all [vacation rentals in Greencastle](https://www.expedia.co.uk/Greencastle-Holiday-Rentals.d553248634983462000.Travel-Guide-HolidayRentals). ### If I need to cancel my hotel reservation in Greencastle, will I receive a refund? > Yes, the majority of hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983462000&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Greencastle. ### How is it to stay in Greencastle? > Visitors will definitely enjoy all that Greencastle has to offer. There are 43 hotels and other accommodation options in the surrounding area. Find out more about [Greencastle](https://www.expedia.co.uk/Greencastle.dx553248634983462000). ### What should I do while I'm visiting Greencastle? > [Thousand Hills State Park](https://www.expedia.co.uk/Thousand-Hills-State-Park-Kirksville.d553248621532649029.Attraction) is one of the places to visit in the surrounding area. Take a look at what more there is to see and do in Expedia's [Greencastle guide](https://www.expedia.co.uk/Greencastle.dx553248634983462000). ### What's the seasonal weather like in Greencastle? > The hottest months are usually July and August, with an average temperature of 23°C, while the coldest months are January and February, with an average of 0°C. 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[Milan Holidays](https://www.expedia.co.uk/Milan.d3000445240.Holidays-City-Breaks) - [Visit Moberly](https://www.expedia.co.uk/Moberly.dx8708) - [Visit Northeast Missouri](https://www.expedia.co.uk/Northeast-Missouri.dx6058818) - [Car hire in Budget Carrer De Can Rius 16-18, Llevant](https://www.expedia.co.uk/Budget-at-Carrer-De-Can-Rius-16-18.v102383.Car-Rental-Guide-Location) - [Car hire Breckenridge](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Breckenridge.d553248634983084594.Car-Hire-Guide) - [Rental cars Kirksville Municipal airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Kirksville-Municipal.d6028673.Car-Hire-Guide) - [Car hire in National Car Rental Airport Terminal 1 Intl Depart Counter 708 Ground Floor 226](https://www.expedia.co.uk/National-Car-Rental-at-Airport-Terminal-1-Intl-Depart-Counter-708-Ground-Floor-226-Belgrade-SRB.v107037.Car-Rental-Guide-Location) - [Ok Mobility Rental Cars in Northeast Missouri](https://www.expedia.co.uk/OK-Mobility-Car-Rentals-In-Northeast-Missouri.d6058818-c1057.Car-Rental-Guide-Suppliers) - 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