Grand Isle Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

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    Better together

    Save up to £335 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Packages with flights are ATOL protected

Your Grand Isle Holiday

Make planning your travels stress-free by creating a holiday package to Grand Isle. We'll take care of the minutiae, so you can focus on discovering everything this neighbourhood has to offer. What to see first? Your trip to Grand Isle wouldn't be complete without stopping at nearby Mexico Beach. Stop daydreaming and start doing. When you're ready to lock in your next holiday to Grand Isle, Expedia will help you get there.

Where to stay in Grand Isle

Find the best Grand Isle areas and neighborhoods for the activities you enjoy most. Learn more about Grand Isle
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Downtown Port St. Joe

If you're spending some time in Downtown Port St. Joe, Port Saint Joe City Hall and Port St. Joe Marina are top sights worth seeing.

Find hotels in Downtown Port St. Joe

Top hotels in Grand Isle

Days Inn by Wyndham Panama City/Callaway

Days Inn by Wyndham Panama City/Callaway

2 out of 5
435 North Tyndall Parkway, Hwy 98 & Hwy 22, Panama City, FL
Fully refundableReserve now, pay when you stay
The price is £50 per night from 18 Aug to 19 Aug
£50
18 Aug - 19 Aug
includes taxes & fees
6.6/10 (449 reviews)
"This property was right across from the beach. And the pool over looking the water was very nice"

Reviewed on 3 Aug 2025

Days Inn by Wyndham Panama City/Callaway
Comfort Suites

Comfort Suites

2.5 out of 5
264 N Tyndall Pkwy, Panama City, FL
Fully refundableReserve now, pay when you stay
The price is £72 per night from 17 Aug to 18 Aug
£72
17 Aug - 18 Aug
includes taxes & fees
8.4/10 Very Good! (684 reviews)
"It was not too far from the beach and other activities"

Reviewed on 7 Aug 2025

Comfort Suites
Extended Stay America Select Suites - Panama City - Callaway

Extended Stay America Select Suites - Panama City - Callaway

2.5 out of 5
902 N Tyndall Parkway, Panama City, FL
Fully refundableReserve now, pay when you stay
The price is £58 per night from 13 Aug to 14 Aug
£58
13 Aug - 14 Aug
includes taxes & fees
6.2/10 (479 reviews)
"Amazing location"

Reviewed on 24 Jul 2025

Extended Stay America Select Suites - Panama City - Callaway
See all 2,153 properties in Grand Isle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Grand Isle travel package cost?
From as little as . Yes, you read that right. Our Grand Isle travel packages are a great way to stretch your budget further. Combine your favourite flights, hotels and rental car and get out and see this exciting destination.
If I'm not able to travel, can I cancel my Grand Isle travel package?
Yes you can, and we're here to help. You may be able to cancel or change your Grand Isle travel package for free within 24 hours of booking. However, you may be charged a fee by your airline, hotel or car rental company if your booking is older than that. If your travel plans suddenly change, browse our Customer Service Portal for further information.
How do I get a cheap travel package to Grand Isle?
Combining your hotel and flight with Expedia won't just save you time — it'll save you a few dollars too. A Grand Isle travel package makes it easy to organise the perfect trip. With more than 550 airlines worldwide to pick from, finding convenient flights that fit your schedule won't be a problem. On top of that, we have over 1,000,000 hotels globally to take your pick of. Talk about choice! No matter who you are, Expedia can show you the world.
Does Expedia offer Book Now, Pay Later Grand Isle holidays?
Good news! We do. Expedia has joined forces with online lender Klarna to help you easily pay for your trip in instalments. Simply pick the payment plan best suited to your needs during checkout and take away the stress of budgeting for your next trip. Make sure you bundle your flights, accommodation and activities with Expedia to get the biggest bang for your holiday buck. Take a look at our flexible payment options below:

  • Pay monthly holidays: Make your holiday dreams come true sooner with Klarna's manageable monthly instalment plans. If paying just a little each month works for you, pick this option at checkout.
  • Pay in instalments holidays: If you want to pay off your escape across multiple transactions, holidays paid in instalments might be the best option for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to hit that "book now" button, opt for a low deposit holiday payment plan with Klarna.

Where should I stay in Grand Isle?
Grand Isle is home to several fascinating places to explore, including Mexico Beach. Book a hotel close by and make sightseeing hassle-free.
What are the top hotels in Grand Isle?
If it's your first time staying in Grand Isle, book a room at MainStay Suites or The Port Inn and Cottages, Ascend Hotel Collection. Both hotels have good amenities and are popular options with lots of travellers.
How far in advance should I book my Grand Isle holiday?
It's always wise to book early. Air carriers generally advertise flight tickets around a year prior to departure, and this is an excellent opportunity to pick up some of the cheapest prices. Boss just told you to take some holiday time next month? No problem! Expedia are never short of fantastic bargains to send you off on the getaway of your dreams, at an affordable price.
What does an Expedia Grand Isle travel package include?
With Expedia, you can select any combination of hotels, flights and car rentals to build your ideal Grand Isle travel package. Once you've made your booking, you can add on fun stuff like day tours and activities. Remember, the more you bundle, the more dollars you'll save!
What should I know before booking a Grand Isle travel package?
Locking in all the parts of your trip together is a terrific way to save. Combine your car rentals, flights and hotels into one package. But you're not restricted to hotels. Expedia has all sorts of properties, including holiday rentals such as beachfront villas and short-term homes. You've got loads of choices!
Can I choose my airline with a Grand Isle Expedia travel package?
Most definitely. Expedia has more than 550 partner airlines to select from across the world. With such a big range of choice, finding the ideal carrier to whisk you away to Grand Isle will be easy.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.