What's it like in East End?

Travellers will be sure to find plenty to entertain them in Sanibel's East End neighbourhood. Make sure that you visit Sanibel Island Northern Beach and Sanibel Island Lighthouse as part of your East End travel plans.

Where is the best place to stay in East End?

Based on our traveller data, Sanibel Inn is one of the top choices for your stay in East End. This hotel is a short 6-minute walk from Sanibel Island Southern Beach, and it offers a private beach and a restaurant. Other good choices for your stay in the neighbourhood include Tarpon Tale Inn and Sunshine Island Inn .

How many hotels will I find in the East End area?

Expedia has 620 hotels and other accommodation options in East End to choose from, making this an ideal home base for exploring the greater Sanibel area.

If I need to cancel my hotel reservation in East End, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to view top deals in East End.

What are the top things to see and do in East End?

Dip your toes in the water at Sanibel Island Northern Beach, Sanibel Island Southern Beach and Causeway Islands Beaches while you're in East End. Sanibel Island Lighthouse and Periwinkle Way are also a couple of places to visit in the neighbourhood. Sanibel Sea School, Sanibel Moorings Botanical Gardens and Bailey's Beach are just a few of the places to visit in and around East End. Dunes Golf and Tennis Club and Causeway Islands Beach are also worth a visit when you're out sightseeing in Sanibel.

The Best Hotels in East End, Sanibel - 2026 Updated Prices

A coastal scene with a lighthouse, beach, and ocean.

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Our top choices for East End hotels

A rustic outdoor bathroom with a wooden deck, a white sink, and various seashells scattered around.

1. Tarpon Tale Inn

East End

Marianella

A pathway leading to a pool area with lounge chairs and umbrellas, surrounded by tropical plants and a thatched-roof structure.

2. Sanibel Inn

East End

William

includes taxes & fees

5 Oct - 6 Oct

A beach with a variety of seashells and pebbles.

3. Sanibel Island Beach Resort

Mid Island, 1.3 mi from East End

Shana

includes taxes & fees

5 Oct - 6 Oct

An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

4. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

6.6 mi from East End

Gigette

includes taxes & fees

7 Oct - 8 Oct

A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

5. Residence Inn by Marriott Fort Myers Sanibel

4.6 mi from East End

jennifer

includes taxes & fees

5 Oct - 6 Oct

A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

6. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

4.9 mi from East End

Jorge

includes taxes & fees

11 Oct - 12 Oct

7. The Anchor Inn

Mid Island, 1.1 mi from East End

Jamie

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

8. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

6.4 mi from East End

Robert

includes taxes & fees

8 Oct - 9 Oct

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

9. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

5.3 mi from East End

Ana

includes taxes & fees

5 Oct - 6 Oct

A hotel room with a large bed, two bedside tables with lamps, a nightstand, and a window with curtains.

10. Candlewood Suites Fort Myers Sanibel Gateway by IHG

8 mi from East End

John

includes taxes & fees

6 Oct - 7 Oct

A pathway flanked by palm trees and wooden buildings with thatched roofs.

11. Kona Kai Motel

Mid Island, 1.6 mi from East End

Karen

includes taxes & fees

5 Oct - 6 Oct

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

12. The Lighthouse Resort Inn & Suites

4.7 mi from East End

Donna

includes taxes & fees

2 Nov - 3 Nov

A beach view with rows of empty wine glasses lined up on a balcony.

13. Lani Kai Beachfront Resort

4.9 mi from East End

ROBERT

includes taxes & fees

12 Oct - 13 Oct

A balcony with a table and chairs, large windows, and a view of the sea.

14. The Westin Cape Coral Resort At Marina Village

6.7 mi from East End

Eric

includes taxes & fees

25 Oct - 26 Oct

A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

15. Marriott Sanibel Harbour Resort & Spa

3.1 mi from East End

Charles

includes taxes & fees

18 Oct - 19 Oct

A large, clear swimming pool with multiple lounge areas and palm trees.

16. Margaritaville Beach Resort Fort Myers

4.7 mi from East End

Jose

includes taxes & fees

5 Oct - 6 Oct

An outdoor seating area with tables and chairs, surrounded by palm trees and a thatched-roof structure.

17. Dolphin Key Resort

9.4 mi from East End

james

includes taxes & fees

5 Oct - 6 Oct

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

18. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

9.5 mi from East End

Brett R

includes taxes & fees

11 Oct - 12 Oct

A modern hotel lobby with a seating area, a reception desk, and a dining area.

19. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

9.1 mi from East End

Taylor

includes taxes & fees

1 Nov - 2 Nov

A balcony with tables set for dining, overlooking a beach with palm trees and the ocean.

20. The Bay Inn at Lani Kai

4.9 mi from East End

Andrea

includes taxes & fees

5 Oct - 6 Oct

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Where to stay in East End

Find the best East End areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

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West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

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A street lined with palm trees and a sign for Periwinkle Place Shops.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

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A beach with clear turquoise water, a sandy shore, and a weathered driftwood structure.

Gulf Shores

When in Gulf Shores, you can plan a visit to Bowman's Beach and J. N. Ding Darling National Wildlife Refuge, some noteworthy sights in the nearby area.

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Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

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Top East End Hotel Reviews

Amazing Direct Ocean Gulf Front Beach Views Condo, pool and hot tub are open!

10/10 Excellent

"The property was beautiful. The balcony was the best part! Property had everything we needed. Can’t wait to come back."

Luxury Villa Lighthouse Across from the Beach

8/10 Good

"The property is beautiful. Great location. Close to everything. We walked to the beach. Watched the manatees and iguanas in the back yard. I don't remember seeing in the addbut their were bikes and beach buggies loaded and ready for borrow. There were a few issues with our stay but Break Away was great and very responsive to our issues."

The Lovebird-sleeps 3! Great value on Sanibel-walk to dining, shops and Historic East End Lighthouse

8/10 Good

"Cute little cottage. The shower was Quite small. Could have used another table for kitchen prep, dish drying, etc but we made it work. Free bicycles and some beach stuff. Outdoor shower/Clean up area. Great beaches!! Overall great stay on Sanibel Island!"

Beachfront Condo + Heated Pool, Hot Tub, Tennis + Walk to Dining

10/10 Excellent

"We loved Jill's condo! The location was excellent. Short walk over the boardwalk to the beach was lovely. Water station to rinse off sandy feet and beach items was so handy too. The newly renovated community pool was outstanding. Lots of pool items to use from floats to noodles...we were so thankful to have access to them because we didn't bring our own since we flew down. The condo was great and fit our family of 5. The kitchen was all we needed for a week stay and many meals at the condo. The screened in balcony had a beautiful view of the ocean and pool and the screen kept out the pesky no-see-um flies. There was also a closet filled with beach chairs, beach umbrellas, and beach toys. Beach towels and bath towels were also included. So wonderful to have these! Thank you!! :)"

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Our top choices for East End hotels

1. Tarpon Tale Inn

2. Sanibel Inn

3. Sanibel Island Beach Resort

4. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

5. Residence Inn by Marriott Fort Myers Sanibel

6. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

7. The Anchor Inn

8. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

9. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

10. Candlewood Suites Fort Myers Sanibel Gateway by IHG

11. Kona Kai Motel

12. The Lighthouse Resort Inn & Suites

13. Lani Kai Beachfront Resort

14. The Westin Cape Coral Resort At Marina Village

15. Marriott Sanibel Harbour Resort & Spa

16. Margaritaville Beach Resort Fort Myers

17. Dolphin Key Resort

18. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

19. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

20. The Bay Inn at Lani Kai

Where to stay in East End

Mid Island

West End

Beachview Country Club Estates

Gulf Shores

Sanctuary

Top East End Hotel Reviews

Amazing Direct Ocean Gulf Front Beach Views Condo, pool and hot tub are open!

Frequently asked questions