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Search Hotels Near Florida Keys National Marine Sanctuary, Key West

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5 Sept - 6 Sept
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6 Sept - 7 Sept
Next weekend
11 Sept - 13 Sept
In two weeks
18 Sept - 20 Sept

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Our top choices for Florida Keys National Marine Sanctuary hotels

1. Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
Downtown Key West, 0.6 mi from Florida Keys National Marine Sanctuary
United States
John
£152
includes taxes & fees
9 Sept - 10 Sept
Almond Tree Inn Hotel - Adults Only

2. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
Uptown - Upper Duval, 0.5 mi from Florida Keys National Marine Sanctuary
United States
Nicholas
£149
includes taxes & fees
7 Sept - 8 Sept
Orchid Key Inn - Adults Only

3. Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
Historic Seaport, 0.6 mi from Florida Keys National Marine Sanctuary
United States
Robin
£124
includes taxes & fees
9 Sept - 10 Sept
Simonton Court Historic Inn & Cottages

4. The Gardens Hotel

The Gardens Hotel
Downtown Key West, 0.5 mi from Florida Keys National Marine Sanctuary
United States
Brian
£140
includes taxes & fees
7 Sept - 8 Sept
The Gardens Hotel

5. The Marquesa Hotel

The Marquesa Hotel
Old Town Key West, 0.6 mi from Florida Keys National Marine Sanctuary
United States
LISA
£201
includes taxes & fees
21 Sept - 22 Sept
The Marquesa Hotel

6. The Porch on Frances Inn

The Porch on Frances Inn
Old Town Key West, 1 mi from Florida Keys National Marine Sanctuary
United States
Corrynne
£116
includes taxes & fees
7 Sept - 8 Sept
The Porch on Frances Inn

7. H2O Suites - Adults Only

H2O Suites - Adults Only
Uptown - Upper Duval, 0.7 mi from Florida Keys National Marine Sanctuary
United States
Kourosh
£261
includes taxes & fees
8 Sept - 9 Sept
H2O Suites - Adults Only

8. The Conch House Heritage Inn

The Conch House Heritage Inn
Old Town Key West, 0.7 mi from Florida Keys National Marine Sanctuary
United States
John
£148
includes taxes & fees
13 Sept - 14 Sept
The Conch House Heritage Inn

9. Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Old Town Key West, 1.1 mi from Florida Keys National Marine Sanctuary
United States
Jaime
£110
includes taxes & fees
8 Sept - 9 Sept
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

10. Duval House

Duval House
Downtown Key West, 0.5 mi from Florida Keys National Marine Sanctuary
United States
Robert
£94
includes taxes & fees
8 Sept - 9 Sept
Duval House

11. Douglas House - Adults Only

Douglas House - Adults Only
Uptown - Upper Duval, 0.6 mi from Florida Keys National Marine Sanctuary
United States
michael
£95
includes taxes & fees
8 Sept - 9 Sept
Douglas House - Adults Only

12. Tropical Inn

Tropical Inn
Downtown Key West, 0.5 mi from Florida Keys National Marine Sanctuary
United States
Anthony
£145
includes taxes & fees
7 Sept - 8 Sept
Tropical Inn

13. Island City House Hotel

Island City House Hotel
Historic Seaport, 0.8 mi from Florida Keys National Marine Sanctuary
United States
Paul
£128
includes taxes & fees
7 Sept - 8 Sept
Island City House Hotel

14. The Grand Guesthouse

The Grand Guesthouse
Old Town Key West, 1 mi from Florida Keys National Marine Sanctuary
United States
Travis
£147
includes taxes & fees
7 Sept - 8 Sept
The Grand Guesthouse

15. The Mermaid & Alligator

The Mermaid & Alligator
Old Town Key West, 0.8 mi from Florida Keys National Marine Sanctuary
United States
Johnny
£150
includes taxes & fees
7 Sept - 8 Sept
The Mermaid & Alligator

16. Santa Maria Suites

Santa Maria Suites
Uptown - Upper Duval, 0.8 mi from Florida Keys National Marine Sanctuary
United States
June Young
£282
includes taxes & fees
7 Sept - 8 Sept
Santa Maria Suites

17. Silver Palms Inn & Historic Homes

Silver Palms Inn & Historic Homes
Old Town Key West, 0.8 mi from Florida Keys National Marine Sanctuary
United States
Shawn
£117
includes taxes & fees
8 Sept - 9 Sept
Silver Palms Inn & Historic Homes

18. Westwinds Inn

Westwinds Inn
Historic Seaport, 0.9 mi from Florida Keys National Marine Sanctuary
United States
John
£97
includes taxes & fees
13 Sept - 14 Sept
Westwinds Inn

19. Coco Plum Inn

Coco Plum Inn
Downtown Key West, 0.4 mi from Florida Keys National Marine Sanctuary
United States
Jake
£112
includes taxes & fees
7 Sept - 8 Sept
Coco Plum Inn

20. Ambrosia Key West

Ambrosia Key West
Old Town Key West, 0.7 mi from Florida Keys National Marine Sanctuary
United Kingdom
Kate
£112
includes taxes & fees
8 Sept - 9 Sept
Ambrosia Key West
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Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Almond Tree Inn Hotel - Adults Only
10.0
Exceptional
1,012 reviews
View
Property grounds
Orchid Key Inn - Adults Only
9.8
Exceptional
1,007 reviews
View
Queen with Pool View | Minibar, in-room safe, iron/ironing board, free WiFi
Simonton Court Historic Inn & Cottages
9.8
Exceptional
1,005 reviews
View
Exterior detail
The Gardens Hotel
9.8
Exceptional
1,003 reviews
View
Exterior
The Marquesa Hotel
9.8
Exceptional
1,002 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

8/10 Good
"Other then the ceiling fan and ceiling fan light coming on and off ( all night long)because next rooms remote worked ours to, huge pain in the rear , it was a good hotel great location for bar crawling"
Kenneth 2-night trip
Posted 6 hours ago
Southernmost Beach Resort and Guesthouses
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

10/10 Excellent
"A beautiful gem of property. Perfect location, close to downtown but far enough away to be peaceful. VERY nice breakfast buffet, simple but everything you need. On demand Starbucks coffee machine in the lobby. Social hour features nuts, crackers and cheese and decent wine. Nice touch. Quite an old property but steps are being taken to refurbish. This is not fancy ritzy property, it is exactly what you want for a quaint relaxing stay. As with all of Key West, this place has chickens. That can be quite aggressive and are not supposed to be fed. Ground maintenance tries hard to keep the area clean, but you have to constantly dodge chicken poop Parking is expensive, but well worth it since you can walk just about anywhere"
Lark 2-night trip
Posted 14 hours ago
The Cabana Inn Key West - Adults Only
Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only

10/10 Excellent
"Great check in experience. Room was very nice and roomy! We didn’t eat breakfast- just grabbed coffee. I’d stay here again."
Pilar 2-night trip
Posted 1 day ago
Orchid Key Inn - Adults Only
Southwinds Motel

Southwinds Motel

8/10 Good
"It was small and old fashioned, but it had an old Florida vibe that we loved. Everything we needed was there. The staff were very helpful."
Michele 2-night trip
Posted 1 day ago
Southwinds Motel
Douglas House - Adults Only

Douglas House - Adults Only

10/10 Excellent
"Great place to stay! Awesome Property and Management!"
michael 1-night trip
Posted 1 day ago
Douglas House - Adults Only
Pier House Resort & Spa

Pier House Resort & Spa

10/10 Excellent
"Great place , beach , pool are the best"
Patrick Sean 4-night trip
Posted 1 day ago
Pier House Resort & Spa
Lighthouse Hotel - Key West Historic Inns

Lighthouse Hotel - Key West Historic Inns

10/10 Excellent
"Loved the look and feel of the property, an oasis within Old Town. Walkable, near everything. Loved the ability to use the bikes, which we used constantly the whole time. Lovely grounds, pool, room, staff. I will be coming back to this property over and over again."
Lance 2-night trip
Posted 1 day ago
Lighthouse Hotel - Key West Historic Inns
Tranquility Guest House

Tranquility Guest House

10/10 Excellent
"The room was clean and the staff was very friendly. Highly recommended"
Mutlu 2-night trip
Posted 2 days ago
Tranquility Guest House
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

10/10 Excellent
"The staff were outstanding, especially Anna at the front desk. They all were so warm and welcoming. The rooms were spacious and clean. The pool was clean and mostly quiet (which was nice and relaxing)."
sharon 3-night trip
Posted 3 days ago
Hyatt Centric Key West Resort and Spa

Other attractions near Florida Keys National Marine Sanctuary

A yellow exhibit labeled 'NOAA's AQUARIUS UNDERSEA LAB' with a circular window and a door.

Florida Keys Eco - Discovery Center

8.8/10 (128 reviews)
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
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A brick corridor with arched ceilings and benches.

Fort Zachary Taylor Historic State Park

9.0/10 (4,544 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
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A wooden signpost with directional arrows pointing to various cities and their distances.
Photo by Martin Pettersson

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
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The Monroe County Courthouse with a clock tower, surrounded by trees and a clear blue sky.

Jackson Square

8.8/10 (110 reviews)
You can learn about the history of Key West with a trip to Jackson Square. Stroll along the seaside or discover the area's beautiful sunsets.
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Coffee Butler Amphitheater

You can make plans for a show at Coffee Butler Amphitheater during your trip to Key West. Discover the area's lively bars and its entertainment choices.
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USCGC Ingham Maritime Museum

You can spend an afternoon browsing the exhibits at USCGC Ingham Maritime Museum during your trip to Key West.
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Truman Waterfront Park

You can take time to visit Truman Waterfront Park during your travels to Key West. Discover the area's lively bars and its great live music.
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We Cycle Key West

You can do some window-shopping at We Cycle Key West during your stay in Key West.
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Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, cycling and lively festivals. If you're looking for a convenient place to stay, take a look at the 1492 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Florida Keys National Marine Sanctuary?
Adjacent to Florida Keys National Marine Sanctuary, Tranquility Guest House is one of the top choices for your stay based on our traveller data, and this hotel offers an outdoor pool and free WiFi. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.
How many hotels will I find near Florida Keys National Marine Sanctuary?
Expedia has 1492 hotels and other accommodation options within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals near Florida Keys National Marine Sanctuary.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Coffee Butler Amphitheater and Key West Film Society if you're interested in local theatre.