Beginning of main content
Nectar
Collect Nectar points

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Top Trending Hotels Near Florida Keys National Marine Sanctuary

See all 415 Hotels near Florida Keys National Marine Sanctuary

Get 200 Nectar points when you book your hotel

Simply enter your Nectar card number when prompted. Your points will be credited 30 days after you return from your trip.

Southernmost Beach Resort

Southernmost Beach Resort

0.6 mi from Florida Keys National Marine Sanctuary
    4.0 out of 5.0
     
     

    Located in Key West, this beachfront hotel is in the city centre and within 1 mi (2 km) of South Beach, Fort Zachary Taylor Historic State Park and Southernmost ...

    £192 per night for 2 guests

    Southernmost Beach Resort£192
    Weatherstation Inn

    Weatherstation Inn

    0.4 mi from Florida Keys National Marine Sanctuary
      2.5 out of 5.0
       
       

      Situated in the historical district, this boutique bed & breakfast is within a 5-minute walk of Harry S. Truman Little White House and Audubon House and Tropical ...

      £165 per night for 2 guests

      Weatherstation Inn£165
      Marrero's Guest Mansion

      Marrero's Guest Mansion

      0.4 mi from Florida Keys National Marine Sanctuary
        3.5 out of 5.0
         
         

        Located in Key West Historic District, this bed & breakfast is steps away from Jackson Square, San Carlos Institute - Casa Cuba and Key West Film Society.

        £136 per night for 2 guests

        Marrero's Guest Mansion£136
        The Cabana Inn Key West-Adults Only

        The Cabana Inn Key West-Adults Only

        0.4 mi from Florida Keys National Marine Sanctuary
          3.0 out of 5.0
           
           

          Located in Key West Historic District, this guesthouse is within a 10-minute walk of Jackson Square, Ernest Hemingway Home and Museum and Audubon House and Tropical ...

          £124 per night for 2 guests

          The Cabana Inn Key West-Adults Only£124
          Heron House - Adult Only

          Heron House - Adult Only

          0.6 mi from Florida Keys National Marine Sanctuary
            3.5 out of 5.0
             
             

            Located in Key West Historic District, this bed & breakfast is within a 10-minute walk of San Carlos Institute - Casa Cuba, Audubon House and Tropical Gardens ...

            £107 per night for 2 guests

            Heron House - Adult Only£107
            2CoolFish Apartment 2

            2CoolFish Apartment 2

            0.3 mi from Florida Keys National Marine Sanctuary
              3.5 out of 5.0
               
               

              Situated in Key West, this condo is close to Jackson Square, Audubon House and Tropical Gardens and Ernest Hemingway Home and Museum. Also nearby are Mallory ...

              2CoolFish Apartment 2Get Rates

              2CoolFish Apartment 2Get Rates
              The Southernmost Inn-Adults Only

              The Southernmost Inn-Adults Only

              0.6 mi from Florida Keys National Marine Sanctuary
                2.5 out of 5.0
                 
                 

                Located in Key West Historic District, this hotel is within a 10-minute walk of Key West Butterfly and Nature Conservatory and Ernest Hemingway Home and Museum. ...

                £118 per night for 2 guests

                The Southernmost Inn-Adults Only£118
                The Marker Waterfront Resort Key West

                The Marker Waterfront Resort Key West

                0.8 mi from Florida Keys National Marine Sanctuary
                  4.0 out of 5.0
                   
                   

                  Located in Key West Historic District, this hotel is within 1 mi (2 km) of Mallory Square and Florida Keys National Marine Sanctuary. Southernmost Point is 1.5 ...

                  £162 per night for 2 guests

                  The Marker Waterfront Resort Key West£162
                  Ocean Key Resort - A Noble House Resort

                  Ocean Key Resort - A Noble House Resort

                  0.7 mi from Florida Keys National Marine Sanctuary
                    4.0 out of 5.0
                     
                     

                    Located in Key West Historic District, this spa resort is steps away from Ripley's Believe It or Not and Mallory Square. Audubon House and Tropical Gardens and ...

                    Pier House Resort & Spa

                    Pier House Resort & Spa

                    0.7 mi from Florida Keys National Marine Sanctuary
                      4.0 out of 5.0
                       
                       

                      Located in Key West Historic District, this beachfront resort is in the city centre, just steps away from Ripley's Believe It or Not, Key West Shipwreck Museum ...

                      £249 per night for 2 guests

                      Pier House Resort & Spa£249