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Top Trending Hotels Near Florida Keys National Marine Sanctuary

Almond Tree Inn Hotel - Adults Only

3.5 star property
10.0 out of 10, Exceptional, (1010)
"Wonderful little hotel that was relaxing with great breakfast. "
The price is £155
includes taxes & fees
4 Sept - 5 Sept
Almond Tree Inn Hotel - Adults Only

The Gardens Hotel

4.0 star property
9.8 out of 10, Exceptional, (1003)
"What a fantastic place this is, very clean and classy. I would stay here again!"
The price is £161
includes taxes & fees
10 Sept - 11 Sept
The Gardens Hotel

Orchid Key Inn - Adults Only

3.5 star property
9.8 out of 10, Exceptional, (1010)
"Excellent friendly staff and beautiful property. "
The price is £155
includes taxes & fees
2 Sept - 3 Sept
Orchid Key Inn - Adults Only

Coco Plum Inn

3.0 star property
9.6 out of 10, Exceptional, (438)
"Great location, nice staff."
The price is £134
includes taxes & fees
3 Sept - 4 Sept
Coco Plum Inn

The Marquesa Hotel

3.5 star property
9.8 out of 10, Exceptional, (1004)
"Beautiful place so really enjoyed it"
The price is £178
includes taxes & fees
22 Sept - 23 Sept
The Marquesa Hotel

Simonton Court Historic Inn & Cottages

2.5 star property
9.8 out of 10, Exceptional, (810)
"Awesome place to stay with a great staff"
The price is £112
includes taxes & fees
10 Sept - 11 Sept
Simonton Court Historic Inn & Cottages

H2O Suites - Adults Only

3.5 star property
9.8 out of 10, Exceptional, (553)
"This was the best stay I had in a long time felt like I was in the safest place in America very friendly environment people are warm and welcoming I will definitely be back soon and the concierge Winfield was amazing during my stay I love the environment and place very relaxing "
The price is £249
includes taxes & fees
4 Sept - 5 Sept
H2O Suites - Adults Only

The Mermaid & Alligator

3.5 star property
9.8 out of 10, Exceptional, (256)
"Absolutely loved staying here and are already looking at dates to come back!"
The Mermaid & Alligator

Weatherstation Inn

2.5 star property
9.4 out of 10, Exceptional, (952)
"The staff went above and beyond for us to have a great vacation and stay! "
The price is £141
includes taxes & fees
8 Sept - 9 Sept
Weatherstation Inn

Duval House

3.0 star property
9.4 out of 10, Exceptional, (1015)
"Perfect location, adequate parking, delicious breakfast!"
The price is £107
includes taxes & fees
1 Sept - 2 Sept
Duval House

Island City House Hotel

3.0 star property
9.6 out of 10, Exceptional, (1001)
"Great location. Appreciated having access to a pool and liked the separate living area with kitchen amenities. "
The price is £138
includes taxes & fees
2 Sept - 3 Sept
Island City House Hotel

Santa Maria Suites

4.0 star property
9.6 out of 10, Exceptional, (1004)
"Best place to stay great staff and the rooms are beautiful "
The price is £226
includes taxes & fees
17 Sept - 18 Sept
Santa Maria Suites

Ambrosia Key West

3.5 star property
9.4 out of 10, Exceptional, (1003)
"Loved the Ambrosia and would definitely stay here again. Location is excellent, very walkable, we didnt need our car for the entire stay. Hotel is quiet and staff are very welcoming. "
The price is £127
includes taxes & fees
2 Sept - 3 Sept
Ambrosia Key West

Ella's Cottages - Key West Historic Inns

3.5 star property
9.4 out of 10, Exceptional, (368)
"Loved our stay. "
The price is £212
includes taxes & fees
8 Sept - 9 Sept
Ella's Cottages - Key West Historic Inns

The Grand Guesthouse

2.5 star property
9.6 out of 10, Exceptional, (1003)
"Great place and a great value. Very clean & a comfortable bed."
The Grand Guesthouse

Westwinds Inn

3.5 star property
9.4 out of 10, Exceptional, (1007)
"Great place with a great staff! Close to everything!"
Westwinds Inn

Southernmost House

4.0 star property
9.4 out of 10, Exceptional, (1009)
"This hotel is beautiful, love the history Bed comfortable Would definitely come and stay here again"
The price is £221
includes taxes & fees
14 Sept - 15 Sept
Southernmost House

Caribbean House

3.0 star property
9.0 out of 10, Wonderful, (258)
"Great stay!"
The price is £101
includes taxes & fees
8 Sept - 9 Sept
Caribbean House

Opal Key Resort & Marina, Key West

4.0 star property
9.2 out of 10, Wonderful, (1014)
"Great stay! "
The price is £245
includes taxes & fees
1 Sept - 2 Sept
Opal Key Resort & Marina, Key West

Paradise Inn Key West - Adults Only

3.5 star property
9.2 out of 10, Wonderful, (1002)
"Great hotel we have stayed here several times and love it every time. "
Paradise Inn Key West - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Florida Keys National Marine Sanctuary Hotel Reviews

Destinations near Key West

Harry S. Truman Little White House
Harry S. Truman Little White House featuring a house

Harry S. Truman Little White House

4.5/5(12 reviews)

Visit the winter home of President Harry S. Truman to see where some of America’s most important post-war decisions were made.

Duval Street
Duval Street

Duval Street

4.5/5(47 reviews)

Along one of the southernmost streets in the continental U.S., enjoy a lively area filled with shops, pubs, restaurants and lots of sidewalk acts and vendors.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?

Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, cycling and lively festivals. If you're looking for a convenient place to stay, take a look at the 1578 hotels and other accommodation options you'll find within a mile.

What's the best place to stay close to Florida Keys National Marine Sanctuary?

Southernmost Beach Resort and Guesthouses is one of the top choices for your stay based on our traveller data, and this hotel offers 3 outdoor pools and a full-service spa. It's located just a short 0.7 mi (1.1 km) from Florida Keys National Marine Sanctuary. Other good choices close by include Hyatt Centric Key West Resort and Spa and La Concha Key West, Autograph Collection.

How many hotels will I find near Florida Keys National Marine Sanctuary?

Expedia has 1578 hotels and other accommodation options within a mile from Florida Keys National Marine Sanctuary.

If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled before the hotel’s cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals near Florida Keys National Marine Sanctuary.

What can I see and do near Florida Keys National Marine Sanctuary?

Florida Keys Eco - Discovery Center, Harry S. Truman Little White House and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Red Barn Theater, Waterfront Playhouse and Key West Film Society if you're interested in local theatre.