A field with a truck and a power line.

Search Business Hotels in Eastern South Dakota

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Eastern South Dakota Business Hotels

Tonight
13 Oct - 14 Oct
Tomorrow
14 Oct - 15 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Eastern South Dakota business-friendly hotels

A compact bathroom with a white sink, a bathtub, and a large mirror.
A grassy area with several evergreen trees.
A hotel lobby with a dining area, a kitchen, and a staircase leading to an upper floor.
An indoor swimming pool with clear water, surrounded by wooden walls and a tiled floor. There are chairs and a table near the pool, and a clock on the wall.

1. De Smet Super Deluxe Inn and Suites

De Smet Super Deluxe Inn and Suites
De Smet
United States
T
£83
includes taxes & fees
12 Nov - 13 Nov
De Smet Super Deluxe Inn and Suites
An outdoor patio area with seating and a fire feature, surrounded by modern architecture and plants.
A group of people at a social event in a spacious indoor venue with tables and chairs arranged for dining or socializing.
A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.
A modern lobby with a white sofa, pendant lighting, and a gold sculpture.

2. Holiday Inn Express & Suites Sioux City North-Event Center by IHG

Holiday Inn Express & Suites Sioux City North-Event Center by IHG
Dakota Dunes
United States
Dustin and Karen
£77
includes taxes & fees
12 Nov - 13 Nov
Holiday Inn Express & Suites Sioux City North-Event Center by IHG
A hotel room with a large bed, a separate bathroom with a bathtub, and a seating area.
A hotel hallway with carpeted floors and doors on both sides.
A reception desk with a wooden finish and a sign that reads "American Inn." There is a refrigerator stocked with beverages and snacks, and a small shelf with various items.
A multi-story American Inn with a prominent sign, a covered entrance, and a landscaped driveway.

3. AmericInn by Wyndham Hartford SD

AmericInn by Wyndham Hartford SD
Hartford
United States
Laurel
£68
includes taxes & fees
25 Oct - 26 Oct
AmericInn by Wyndham Hartford SD
A hotel room with a large bed, a blue sofa, a nightstand with a lamp, and a mural of a waterfall on the wall.
A hotel lobby with a fireplace, seating area, and a bar.
A multi-story hotel with a covered entrance, brick facade, and a large tree in front.
A spacious indoor area with tables and chairs, large windows, and a kitchenette area.

4. Clarion Pointe Sioux Falls Airport

Clarion Pointe Sioux Falls Airport
Northwest Sioux Falls
United States
Roger
£74
includes taxes & fees
25 Oct - 26 Oct
Clarion Pointe Sioux Falls Airport
A modern bar area with a wooden ceiling, bar stools, and a variety of liquor bottles.
Room
A bar area with a wooden ceiling, multiple shelves of liquor bottles, and bar stools.
A Best Western PLUS hotel with a modern design, featuring a covered entrance and multiple floors.

5. Best Western Plus Lakeview Hotel

Best Western Plus Lakeview Hotel
Madison
United States
Christina
£115
includes taxes & fees
25 Oct - 26 Oct
Best Western Plus Lakeview Hotel
A spacious kitchen with a large island, modern pendant lights, and a ceiling fan.
A modern kitchen with stainless steel appliances, dark wood cabinets, and a tiled floor.
Two people sitting on Adirondack chairs facing a lake, with picnic tables and benches in the background.
A spacious room with wooden walls and ceiling, featuring a large chandelier, multiple windows, and a central seating area with tables and chairs.

6. Lewis and Clark Resort

Lewis and Clark Resort
Yankton
United States
Jeff
£90
includes taxes & fees
4 Nov - 5 Nov
Lewis and Clark Resort
A swimming pool with clear blue water, surrounded by a tiled deck and a seating area with chairs and tables.
A modern hotel room with a kitchenette, a sofa, a dining table, a small round table, a bed, and a view of the outdoors.
A hotel room with a bed, a sofa, a desk, and a chair.
A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and a clear view of the building's facade.

7. Comfort Inn & Suites at Sanford Sports Complex

Comfort Inn & Suites at Sanford Sports Complex
Northwest Sioux Falls
United States
Michelle Marie
£87
includes taxes & fees
25 Oct - 26 Oct
Comfort Inn & Suites at Sanford Sports Complex
A reception area with a wooden reception desk, a computer, and a chair.
A modern kitchen with blue cabinets, a white brick backsplash, and a stainless steel refrigerator.
Exterior
A living room with a fireplace, a clock, and a bookshelf.

8. Country Inn & Suites by Radisson, Dakota Dunes, SD

Country Inn & Suites by Radisson, Dakota Dunes, SD
Dakota Dunes
United States
James
£64
includes taxes & fees
8 Nov - 9 Nov
Country Inn & Suites by Radisson, Dakota Dunes, SD
An indoor swimming pool with arched windows, a 'No Diving' sign, and a lifebuoy.
A hotel lobby with a reception desk, a coffee station, and seating area with chairs and a table.
A hotel with a large driveway, a covered entrance, and a parking area with several vehicles.
A hotel room with a large bed, two bedside lamps, a chair, a window with curtains, and a wall-mounted air conditioner.

9. Super 8 by Wyndham Brookings

Super 8 by Wyndham Brookings
Brookings
Canada
Robert
£64
includes taxes & fees
1 Nov - 2 Nov
Super 8 by Wyndham Brookings
A hotel lobby with a reception desk, seating area, and a view of the outside.
A modern kitchen with a central island, bar stools, and pendant lighting.
A hotel room with a bed, a desk with a television, a blue chair, a blue sofa with a red pillow, and a framed picture on the wall.
An outdoor patio with lounge chairs and a small table, surrounded by trees and a grassy area.

10. Hampton Inn North Sioux City

Hampton Inn North Sioux City
North Sioux City
United States
Crystal
£74
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn North Sioux City
View all properties

Top Eastern South Dakota Hotel Reviews

Clarion Pointe Sioux Falls Airport

Clarion Pointe Sioux Falls Airport

10/10 Excellent
"Everything was awesome, except when we were in the breakfast area of the lobby, they were doing some kind of work on an electric panel or server or something, and the worker was making all sorts of very loud noise during breakfast. Now I understand things sometimes need to be fixed or updated, but it seems like they could have scheduled if after breakfast hours were over?? Other than that the property and staff were great! Definitely would stay again next time we’re in Sioux Falls."
Rana Karin 1-night trip
Posted less than an hour ago
Clarion Pointe Sioux Falls Airport
Microtel Inn & Suites by Wyndham Sioux Falls

Microtel Inn & Suites by Wyndham Sioux Falls

10/10 Excellent
"Clean room and would stay here again"
Cheryl 1-night trip
Posted 2 hours ago
Microtel Inn & Suites by Wyndham Sioux Falls
Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls

10/10 Excellent
"Great stay! Hot tub not working, which was disappointment because I had specifically called about it in the morning. Otherwise wonderful property, breakfast and location."
Dennette 1-night trip
Posted 2 hours ago
Clubhouse Hotel Suites Sioux Falls
AeroStay Hotel

AeroStay Hotel

10/10 Excellent
"So handy to park for both the airport and hotel."
Leisha 1-night trip
Posted 2 hours ago
AeroStay Hotel
Kelly Inn & Suites Mitchell South Dakota

Kelly Inn & Suites Mitchell South Dakota

10/10 Excellent
"Friendly staff makes you feel welcome"
Daniel 1-night trip
Posted 3 hours ago
Kelly Inn & Suites Mitchell South Dakota
Country Inn & Suites by Radisson, Sioux Falls

Country Inn & Suites by Radisson, Sioux Falls

10/10 Excellent
"Definitely would stay again! Not the best location, but what is during construction season. I would highly recommend, even if the shower had a teeny tiny drip. :)"
Jen 1-night trip
Posted 9 hours ago
Country Inn & Suites by Radisson, Sioux Falls
Thunderbird Lodge

Thunderbird Lodge

10/10 Excellent
"Very clean. There updating the property. Price was great. Recommend to stay here"
Nicole 1-night trip
Posted 13 hours ago
Thunderbird Lodge
La Quinta Inn & Suites by Wyndham Sioux Falls

La Quinta Inn & Suites by Wyndham Sioux Falls

8/10 Good
"Other guests need to be aware that they allow pets. Had a dog barking in the lobby area."
Warren 1-night trip
Posted 1 day ago
La Quinta Inn & Suites by Wyndham Sioux Falls
The Dakota

The Dakota

10/10 Excellent
"Staff made sure we had what we needed. Mind you, we were there a short time, so never saw cleaning staff."
Lorraine 3-night trip
Posted 1 day ago
The Dakota

Frequently asked questions

How much do business hotels in Eastern South Dakota cost?
Expect to pay between £51 and £115 per night for business hotels in Eastern South Dakota. Top deals on stays that are suitable for corporate travellers are just a few clicks away on Expedia. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business hotels are there in Eastern South Dakota?
Eastern South Dakota has 114 business hotels to pick from. Whether you're hosting a conference or meeting or working remotely, these properties come with the services and amenities you need to be productive.
Why book your business hotel in Eastern South Dakota with Expedia?
Here at Expedia, we make it our job to help you locate the perfect stay at the right price. From fancy, corporate-friendly retreats to affordable motor inns loaded with amenities, you'll have your next work trip booked in a few quick clicks.
How can I find cheap business hotels in Eastern South Dakota?
Select the "business friendly" filter, located just under the "traveller experience" heading, to find cheap business hotels in Eastern South Dakota. Then refine your search by your per-night budget. Choosing a stay away from the centre is another good way to save.

Explore a world of travel with Expedia