East Seneca Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to £335 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Packages with flights are ATOL protected

Your East Seneca Holiday

Say bye-bye to the stress of planning and hello to a East Seneca holiday package. With your travel details organised before you leave, you can focus on discovering this city, starting with Downtown Buffalo, which is great for nightlife, shopping and bars and pubs. A trip to East Seneca is a superb opportunity to sightsee. Check out well-known attractions like Highmark Stadium, Buffalo and Erie County Botanical Gardens and Walden Galleria Mall. Don't put off exploring this city any longer. The ultimate East Seneca holiday is a few clicks away with Expedia.

Where to stay in East Seneca

Find the best East Seneca areas and neighborhoods for the activities you enjoy most. Learn more about East Seneca
Buffalo which includes a monument, a skyscraper and a city

Downtown Buffalo

4 out of top 10 points of interest in this area
4.5/5(10 area reviews)

Known for its great bars and great live music, there's plenty to explore in Downtown Buffalo. You can visit top attractions like Chippewa District and Statler Tower, and jump on the metro at Fountain Plaza Station or Lafayette Square Station to see more of the city.

Find hotels in Downtown Buffalo

Top hotels in East Seneca

M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave, Buffalo, NY
Fully refundableReserve now, pay when you stay
The price is £83 per night from 21 Aug to 22 Aug
£83
21 Aug - 22 Aug
includes taxes & fees
7.2/10 Good! (1,960 reviews)
"Good trip"

Reviewed on 18 Aug 2025

M Hotel Buffalo
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza, Buffalo, NY
Fully refundableReserve now, pay when you stay
The price is £107 per night from 1 Sept to 2 Sept
£107
1 Sept - 2 Sept
includes taxes & fees
7.8/10 Good! (1,501 reviews)
Happy one nighters
"The desk, valet and staff were friendly and welcoming. An item was left in the room and housekeeping retrieved it and held it until we were able to return."

Reviewed on 19 Aug 2025

Hyatt Regency Buffalo / Hotel and Conference Center
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St, Buffalo, NY
Fully refundableReserve now, pay when you stay
The price is £80 per night from 20 Aug to 21 Aug
£80
20 Aug - 21 Aug
includes taxes & fees
7.8/10 Good! (2,611 reviews)
"I like the rooms space and the air conditioner"

Reviewed on 17 Aug 2025

Buffalo Airport Hotel
See all 759 properties in East Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does an East Seneca travel package cost?
We make it simple to explore the world, with East Seneca packages starting from just . You'll have the flexibility to bundle your preferred hotels, airlines and car rental. For the ultimate escape, why not add some activities and tours to your itinerary?
If I'm not able to travel, can I cancel my East Seneca travel package?
Yes, you can. We totally understand that things don't always go to plan, so we're happy to help if you have to make changes to your East Seneca travel package. It may be possible to cancel or amend your itinerary at no cost if you've booked in the last 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Look up our Customer Service Portal for more information. Also, check your itinerary for the nitty-gritty on change fees.
How do I get a cheap travel package to East Seneca?
Booking a flight and hotel together with Expedia won't just save precious time — it'll save you a nice amount too. An East Seneca travel package makes it easy to put together the ideal trip. With more than 550 airlines throughout the world to pick from, finding flights that suit your busy schedule will be no sweat. On top of that, we've got over 1,000,000 hotel options globally to take your pick of. Talk about choice! No matter who you are, Expedia brings the world within your reach.
Does Expedia offer Book Now, Pay Later East Seneca holidays?
Expedia has joined forces with online lender Klarna to make booking your next break a little easier on the wallet. Paying in instalments means you can spread the costs of your next adventure, leaving you with more cash to splash while you're away. Klarna has several payment plans to pick from, so you're sure to find something that falls within your budget. Browse these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month sounds best for you, Klarna offers just that! Paying in easy monthly instalments will make that dream holiday possible.
  • Pay in instalments holidays: If you'd prefer to pay off your getaway across multiple transactions, holidays paid in instalments might be right for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: Pressing the "book now" button is easier with this payment plan. Simply put down a small deposit on your booking and then start packing your suitcase.

Where should I stay in East Seneca?
With so much to do in East Seneca, we recommend you book a room in a hotel close to its attractions. Charles E. Burchfield Nature and Art Centre, Southgate Plaza and Enjoy The Journey Art Gallery are some good ones to put on your to-do list.
What are the top hotels in East Seneca?
Country Inn & Suites by Radisson, Buffalo South I-90, NY and Hampton Inn Buffalo South I90 are a couple of the most sought-after hotels in East Seneca. Why not look up the amenities and facilities at each and then decide?
How far in advance should I book my East Seneca holiday?
To bag rock-bottom prices, book early. Airlines typically release flights, along with some of the lowest fares, up to 12 months in advance. Hotels, car rental and activities should also be booked early so you can have the pick of the bunch. If you've decided on a last-minute getaway in East Seneca, there are always plenty of great deals to be had on Expedia. Book something in today!
What does an Expedia East Seneca travel package include?
Flights, rental cars and hotels, or any combination of them — it's totally up to you. Whether you're venturing to East Seneca on a family road trip or travelling by yourself, there's a bundle to suit your budget and style. Once you've made your booking, why not add on one or two tours and experiences?
What should I know before booking an East Seneca travel package?
Design deals to match your budget with an Expedia package. Flights, hotels, rental cars — we've got everything you need to plan your getaway. You'll save a tidy sum just by combining your bookings. Whether you're going on a ski trip or relaxing on a sunny beach, your ideal getaway is just a few clicks away.
Can I choose my airline with an East Seneca Expedia travel package?
Expedia has access to more than 550 airline partners worldwide, so you certainly can. Just choose your preferred air carrier and create the perfect East Seneca getaway.

Popular places to visit

University At Buffalo - North Campus

University At Buffalo - North Campus

Walk around the campus of University At Buffalo - North Campus, a top university in Amherst. Experience the area's great live music and entertainment choices.

University At Buffalo - North Campus

Walden Galleria Mall

You can browse for the perfect souvenirs at Walden Galleria Mall during your visit to Cheektowaga. Experience the area's entertainment choices and acclaimed theatre scene.

Walden Galleria Mall

Things to do

Welcome to the Pan-American Exposition.

Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour

£10
per adult
100% of travellers recommend
Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour
The Station Master

Niagara Falls USA and Underground Railroad Heritage Tour

£93
per adult
Niagara Falls USA and Underground Railroad Heritage Tour
Niagara Falls Self-Guided Driving Audio Tour from Toronto

Niagara Falls Self-Guided Driving Audio Tour from Toronto

£13
per traveller
Niagara Falls Self-Guided Driving Audio Tour from Toronto
See all activities in Buffalo

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.