A coastal scene with a lighthouse, beach, and ocean.

Search Hotels in East End, Sanibel

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
26 Jun - 28 Jun
Next weekend
3 Jul - 5 Jul

Filter by

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Star rating

Our top choices for East End hotels

Property amenity

Tarpon Tale Inn

Tarpon Tale Inn
3.0 star property
East End
9.6 out of 10, Exceptional, (407 reviews)
"Owner is really friendly room is very clean nice place."
United States
Daniel
The price is £181
includes taxes & fees
29 Jun - 30 Jun
Tarpon Tale Inn
Exterior

Sanibel Inn

Sanibel Inn
3.0 star property
East End
9.2 out of 10, Wonderful, (1,006 reviews)
"Wonderful place to stay! Unfortunately the weather wasn’t perfect but the weekend was great and the restaurant was delicious!"
United States
Tracy
The price is £349
includes taxes & fees
28 Jun - 29 Jun
Sanibel Inn
Reception

HomeTowne Studios by Red Roof Fort Myers

HomeTowne Studios by Red Roof Fort Myers
2.5 star property
15.9 mi from East End
8.8 out of 10, Excellent, (21 reviews)
"This is a new hotel and everything was excellent!"
United States
Mercedes E
The price is £72
includes taxes & fees
7 Jul - 8 Jul
HomeTowne Studios by Red Roof Fort Myers
3 restaurants; breakfast, lunch, dinner and brunch served

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
4.9 mi from East End
9.0 out of 10, Wonderful, (1,653 reviews)
"Great place to stay!! We very much enjoyed it!!"
United States
Sherry
The price is £146
includes taxes & fees
1 Jul - 2 Jul
Lani Kai Beachfront Resort
1 King Bed Suite w/ Efficiency Non Smoking | Premium bedding, down duvets, desk, laptop workspace

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral
2.0 star property
13.9 mi from East End
7.6 out of 10, Good, (342 reviews)
"Clean room, nice breakfast and wonderful staff!"
United States
Christina
The price is £54
includes taxes & fees
17 Jul - 18 Jul
Quality Inn Fort Myers Cape Coral
2 outdoor pools, pool cabanas (surcharge), pool umbrellas

The Perry Hotel Naples

The Perry Hotel Naples
4.5 star property
18.2 mi from East End
9.6 out of 10, Exceptional, (895 reviews)
"Great stay!"
United States
Wojciech
The price is £164
includes taxes & fees
5 Jul - 6 Jul
The Perry Hotel Naples
Interior

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
16.1 mi from East End
9.6 out of 10, Exceptional, (1,106 reviews)
"Great staff, awesome airport shuttle!"
United States
Carlos
The price is £70
includes taxes & fees
2 Jul - 3 Jul
Holiday Inn Express & Suites Fort Myers Airport by IHG
View from room

Pointe Estero Beach Resort

Pointe Estero Beach Resort
2.0 star property
8.1 mi from East End
9.2 out of 10, Wonderful, (1,007 reviews)
"The beach view was amazing, very clean property"
United States
Kara
The price is £362
includes taxes & fees
8 Jul - 9 Jul
Pointe Estero Beach Resort
Exterior

Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral
2.5 star property
14.2 mi from East End
7.6 out of 10, Good, (307 reviews)
"Nice place"
United States
najwa
The price is £50
includes taxes & fees
3 Jul - 4 Jul
Woodspring Suites Fort Myers - Cape Coral
Lobby

Days Inn & Suites by Wyndham Bonita Springs North Naples

Days Inn & Suites by Wyndham Bonita Springs North Naples
2.5 star property
18.9 mi from East End
8.0 out of 10, Very good, (1,006 reviews)
"Clean room, great breakfast "
Canada
Prajeshkumar
The price is £64
includes taxes & fees
28 Jun - 29 Jun
Days Inn & Suites by Wyndham Bonita Springs North Naples
Free daily buffet breakfast

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
4.6 mi from East End
8.8 out of 10, Excellent, (1,000 reviews)
"I would stay here again good breakfast nice heated pool good distance to beaches"
United States
Cheryl
The price is £77
includes taxes & fees
28 Jun - 29 Jun
Residence Inn by Marriott Fort Myers Sanibel
Terrace/patio

Hampton Inn Bonita Springs/Naples-North

Hampton Inn Bonita Springs/Naples-North
2.5 star property
16.1 mi from East End
9.0 out of 10, Wonderful, (1,001 reviews)
"Hotel was clean, comfortable quiet great location to get to the beach old downtown Bonita and the restaurant Next-Door, aqua is exceptional as everything you need for a good getaway"
United States
randy
The price is £77
includes taxes & fees
28 Jun - 29 Jun
Hampton Inn Bonita Springs/Naples-North
Deluxe Single Room | Living area | 55-inch Smart TV with cable channels, streaming services

The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 1.1 mi from East End
9.8 out of 10, Exceptional, (48 reviews)
"We had a great time and would definitely stay there again!"
United States
William Edward
The price is £190
includes taxes & fees
23 Jul - 24 Jul
The Anchor Inn
Deluxe King Studio Waterfront | Water view

Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs
3.0 star property
14.8 mi from East End
8.8 out of 10, Excellent, (805 reviews)
"Very convenient hotel to access Bonita Beach. The hotel staff was friendly, everything was clean, the location is beautiful with a dock on the water if you need to get picked up by a boat!"
United States
Colin
The price is £87
includes taxes & fees
30 Jun - 1 Jul
Latitude 26 Waterfront Boutique Resort - Bonita Springs
Exterior

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
4.2 mi from East End
9.4 out of 10, Exceptional, (1,390 reviews)
"Great place to visit"
United States
Karen
The price is £244
includes taxes & fees
1 Jul - 2 Jul
Pink Shell Beach Resort and Marina
Restaurant

The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
4.9 mi from East End
7.8 out of 10, Good, (439 reviews)
"Enjoyed our stay!"
United States
Steve
The price is £134
includes taxes & fees
25 Jun - 26 Jun
The Bay Inn at Lani Kai
Exterior

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
6.6 mi from East End
9.2 out of 10, Wonderful, (1,003 reviews)
"Great location"
United States
Kenneth A.
The price is £71
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Lobby

Fairfield Inn & Suites by Marriott Bonita Springs

Fairfield Inn & Suites by Marriott Bonita Springs
3.0 star property
18.6 mi from East End
9.4 out of 10, Exceptional, (540 reviews)
"Excellent clean hotel"
United States
William
The price is £83
includes taxes & fees
30 Jun - 1 Jul
Fairfield Inn & Suites by Marriott Bonita Springs
View from room

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
4.9 mi from East End
8.2 out of 10, Very good, (1,227 reviews)
"I have stayed here many times it is clean, reasonably priced and local to the island"
United States
Gabriel
The price is £61
includes taxes & fees
14 Jul - 15 Jul
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
BBQ/picnic Area

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
13.3 mi from East End
9.6 out of 10, Exceptional, (272 reviews)
"It was so peaceful"
United States
Jovan
The price is £118
includes taxes & fees
30 Jun - 1 Jul
Matlacha on Shoreview
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in East End

Find the best East End areas for the activities you enjoy most.
A coastal scene with a lighthouse, beach, and ocean.

Mid Island

If you're spending some time in Mid Island, Sanibel Island Southern Beach and Periwinkle Way are top sights worth seeing.

A coastal scene with a lighthouse, beach, and ocean.

West End

If you're spending some time in West End, Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge are top sights worth seeing.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Seashells on Sanibel Island, Florida

Gulf Shores

When in Gulf Shores, you can plan a visit to Bowman's Beach and J. N. Ding Darling National Wildlife Refuge, some noteworthy sights in the nearby area.

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Turner Beach and Castaways Marina.

Top East End Hotel Reviews

Sanibel Inn

Sanibel Inn

10/10 Excellent
"We really enjoyed our stay and plan to return in the future! The room was very clean and well-appointed. Front desk, cabana, tiki bar, and restaurant staff were all extremely friendly and personable. Beautiful grounds. Great pool area. Both the poolside bar and Italian restaurant had excellent food. Plenty of lounge chairs and umbrellas available daily on the beach. Pro-tip for venturing off the resort: bikes are available for rent (free), but there aren’t very many places within close walking- or biking-distance, especially with the heat and humidity. Highly recommend renting a car if you’re planning on doing any shopping or adventuring (Blind Pass Beach on Captiva was absolutely amazing and The Bubble Room has excellent food and was fun to visit.)"
Erin 4-night trip
Posted 16 hours ago
Sanibel Inn

Frequently asked questions

What's it like in East End?
Travellers will be sure to find plenty to entertain them in Sanibel's East End neighbourhood. Looking for sights you might find in a travel guide about East End? Consider a visit to Sanibel Island Southern Beach while you're in the neighbourhood.
Where is the best place to stay in East End?
Based on our traveller data, Sanibel Inn is one of the top choices for your stay in East End. This hotel is a short 6-minute walk from Sanibel Island Southern Beach, and it offers a private beach and a restaurant. Other good choices for your stay in the neighbourhood include Seahorse Cottages on Sanibel - Adults Only and Tarpon Tale Inn.
How many hotels will I find in the East End area?
Expedia has 617 hotels and other accommodation options in East End to choose from, making this an ideal home base for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in East End, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to view top deals in East End.
What are the top things to see and do in East End?
Dip your toes in the water at Sanibel Island Southern Beach, Sanibel Island Northern Beach and Causeway Islands Beaches while you're in East End. Sanibel Island Lighthouse and Periwinkle Way are also a couple of places to visit in the neighbourhood. Sanibel Sea School, Sanibel Moorings Botanical Gardens and Bailey's Beach are just a few of the places to visit in and around East End. Dunes Golf and Tennis Club and Causeway Islands Beach are also worth a visit when you're out sightseeing in Sanibel.