Distrito Santa Isabel Holidays
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Top Distrito Santa Isabel Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
Megapolis Hotel Panamá
San Francisco
Price was £730, price is now £507 per person
£507
per person
24 Jan - 26 Jan
found 2 hours ago
Return flight included
Kingston (KIN) to Panama City (PTY)
8.6/10 Excellent! (1,803 reviews)
La mejor opción sin duda para hospedarse en ciudad de Panamá.
Reviewed on 31 Oct 2026
American Trade Hotel
Casco Viejo
Price was £647, price is now £547 per person
£547
per person
24 Jan - 26 Jan
found 2 hours ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9.4/10 Exceptional! (820 reviews)
The room was clean, and the staff was very attentive. However, the hot water was inconsistent, the shower drain seemed partially clogged, the bathroom lighting was insufficient, and the street noise was loud. Improvements in these areas would make the stay more comfortable.
Reviewed on 27 Oct 2026
Amarla Boutique Hotel Casco Viejo Adults Only
Casco Viejo
Price was £736, price is now £631 per person
£631
per person
24 Jan - 26 Jan
found 2 hours ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9.6/10 Exceptional! (146 reviews)
It was a great place to stay, right in the center of old Panama City. Even though it is small it is very quaint and efficiently run. It is also convenient that they have a restaurant in-house. Just making stuff convenient
Reviewed on 31 Oct 2026
Distrito Santa Isabel Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Top hotels in Distrito Santa Isabel
Caribbean Haven Of Nature 'Preci Beach'
Nombre de Dios Colon
10/10 Exceptional! (32 reviews)
"This is a great place to slow down and enjoy the sea and on-site amenities, including a pool, hot tub, sand volleyball court, and kid-friendly play spaces. This is very much a home that the owners make available to guests. Cone, the on-site custodian, is available and helpful. It is somewhat remote ..."
Reviewed on 2 Oct 2026
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
Santa Isabel Colon
10/10 Exceptional! (31 reviews)
"This was an incredible stay with so many lovely preparation of meals from Lucy and Jose. They were helpful and so thoughtful. We rested, relaxed, and spent leisurely days being together as a family. If only this happened more often! What a great trip. I am sad it ended so soon. Thank you to a wonderful ..."
Reviewed on 1 Jan 2026
Caribbean getaway: beach cottage just on the sand
Palenque Provincia de Colón
Fully refundable
The price is £237 per night from 1 Nov to 2 Nov
£237
1 Nov - 2 Nov
includes taxes & fees
9/10 Wonderful! (4 reviews)
"the view is beautiful! We were taken care of well."
Reviewed on 26 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
