Title: South Eastern Region Gay-Friendly Hotels, Malta: South Eastern Region Hotel Guide | Expedia.co.uk [South Eastern Region Hotels](https://expedia.co.uk/Destinations-In-South-Eastern-Region.d708606516594679808.Hotel-Destinations)[Holiday Rentals in South Eastern Region](https://expedia.co.uk/Destinations-In-South-Eastern-Region.d708606516594679808.Holiday-Rental-Destinations)[South Eastern Region Car Hire](https://expedia.co.uk/Destinations-In-South-Eastern-Region.d708606516594679808.Car-Hire-Destinations)[South Eastern Region Holidays](https://expedia.co.uk/South-Eastern-Region.d708606516594679808.Holidays-City-Breaks) ![A public garden in Valletta with a view over the Grand Harbour, the location of the 1565 Great Siege when the Ottoman Empire tried, unsuccessfully, to invade Malta, then held by the Knights of St John. #Hometown #lifeatexpedia #history](https://images.trvl-media.com/place/2341/f0d37574-d737-4b42-a97e-de9b4bca1245.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michael Camilleri ![](https://images.trvl-media.com/place/2341/f0d37574-d737-4b42-a97e-de9b4bca1245.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## South Eastern Region Accommodation: Most Popular Cities to Stay ![Valletta showing a sunset, heritage architecture and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/85000/85030-Valletta.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Valletta [](https://expedia.co.uk/Valletta-Hotels-Gay-Friendly-Hotel.0-0-d2341-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/2/c1ce5c34cb8bbb990dab997bd339d205.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Birgu [](https://expedia.co.uk/Birgu-Hotels-Gay-Friendly-Hotel.0-0-d6234091-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/2/61e068037f0587d94f940b1bd9b67c58.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Floriana [](https://expedia.co.uk/Floriana-Hotels-Gay-Friendly-Hotel.0-0-d6233901-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/2/6d9f102759634ccd8819e46ef6e91a5f.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Marsaskala [](https://expedia.co.uk/Marsaskala-Hotels-Gay-Friendly-Hotel.0-0-d601857-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![Tarxien Temples showing building ruins](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/85000/85148-Tarxien-Temples.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Tarxien [](https://expedia.co.uk/Tarxien-Hotels-Gay-Friendly-Hotel.0-0-d6234071-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![Grand Harbour which includes a bay or harbour, a coastal town and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/85000/85055-Grand-Harbour.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Senglea [](https://expedia.co.uk/Senglea-Hotels-Gay-Friendly-Hotel.0-0-d6234087-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ## Check availability on South Eastern Region Gay-Friendly Hotels Tonight [12 Feb - 13 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=708606516594679808&startDate=2026-02-12&endDate=2026-02-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Tomorrow [13 Feb - 14 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=708606516594679808&startDate=2026-02-13&endDate=2026-02-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=708606516594679808&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=708606516594679808&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_708606516594679808) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Eastern-Region-Gay-Friendly-Hotel.0-0-d708606516594679808-tGayFriendlyHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Eastern-Region-Gay-Friendly-Hotel.0-0-d708606516594679808-tGayFriendlyHotel.Hotel-Filter-Destinations) ## Top South Eastern Region Hotel Reviews ![The Cumberland Hotel by NEU Collective](https://images.trvl-media.com/lodging/22000000/21950000/21949200/21949161/efa194f2_y.jpg) ### The Cumberland Hotel by NEU Collective 10/10 Excellent "Super convenient location. All of the staff we encountered were pleasant and helpful. Recommend this hotel." [](https://expedia.co.uk/Valletta-Hotels-The-Cumberland-Hotel-By-NEU-Collective.h21949161.Hotel-Information) ![Grand Hotel Excelsior](https://images.trvl-media.com/lodging/2000000/1690000/1685900/1685894/7e68052b_y.jpg) ### Grand Hotel Excelsior 10/10 Excellent "Clean, large room. Good breakfast. Friendly staff . Great location." [](https://expedia.co.uk/Floriana-Hotels-Grand-Hotel-Excelsior.h1685894.Hotel-Information) ![Melior Boutique Hotel](https://images.trvl-media.com/lodging/75000000/74640000/74630900/74630899/f33df52b_y.jpg) ### Melior Boutique Hotel 10/10 Excellent "Polite & very helpful staff. Great service. Very clean and well maintained rooms. Ideal location for staying in Valletta." [](https://expedia.co.uk/Valletta-Hotels-Melior-Boutique-Hotel.h74630899.Hotel-Information) ![Rosselli](https://images.trvl-media.com/lodging/25000000/24950000/24944700/24944700/da3ec971_y.jpg) ### Rosselli 10/10 Excellent "I had a fantastic stay at Rosselli. I’m not even sure where to start…! The staff were really friendly and helpful. The room was wonderful - very comfy bed, great amenities, extremely spacious and even had a sauna! Location is fantastic - right in the middle of Valletta and close to everything but the room was really quiet, which was an unexpected bonus in such a noisy, busy city! Thanks again to the team for such an amazing welcome / stay - I will definitely be back! " [](https://expedia.co.uk/Valletta-Hotels-Rosselli.h24944700.Hotel-Information) ![San Karlu Hotel](https://images.trvl-media.com/lodging/108000000/107080000/107073200/107073143/f0c54f7b_y.jpg) ### San Karlu Hotel 10/10 Excellent "Loved everything about this hotel: great staff, interesting layout and rooms, super quiet location, dramatic rooftop deck and we really appreciated the assistance of Patricia on the desk! We had a sudden need for a hotel for two nights and couldn’t be happier we found this one. " [](https://expedia.co.uk/Valletta-Hotels-San-Karlu-Hotel.h107073143.Hotel-Information) ![The Gomerino Hotel](https://images.trvl-media.com/lodging/69000000/68610000/68601700/68601666/8dc34db9_y.jpg) ### The Gomerino Hotel 10/10 Excellent "This hotel is truly exceptional, the room was spotless, the breakfast was delicious and it is in a fantastic location in Valletta for restaurants and cocktail bars. The staff are excellent and very friendly. Even the prices for drinks out of the in room mini bar are very reasonable for a hotel." [](https://expedia.co.uk/Valletta-Hotels-The-Gomerino-Hotel.h68601666.Hotel-Information) ![Iniala Harbour House](https://images.trvl-media.com/lodging/47000000/46980000/46973500/46973445/7d9a591a_y.jpg) ### Iniala Harbour House 10/10 Excellent "Impeccable service and got an unexpected upgrade to the most luxurious suite. Tasting menu at ION restaurant was amazing. Would definitely recommend - especially the package with the meal and spa treatment and we will be back. " [](https://expedia.co.uk/Valletta-Hotels-Iniala-Harbour-House.h46973445.Hotel-Information) ![19 Rooms](https://images.trvl-media.com/lodging/20000000/19780000/19771200/19771178/2aa6c377_y.jpg) ### 19 Rooms 10/10 Excellent "Very big, comfortable bed. Extra touches like free coffee, cake and local wine was very nice." [](https://expedia.co.uk/Valletta-Hotels-19-Rooms.h19771178.Hotel-Information) ![66 Saint Pauls & Spa](https://images.trvl-media.com/lodging/23000000/22210000/22209400/22209369/6bbe973f_y.jpg) ### 66 Saint Pauls & Spa 10/10 Excellent "Absolutely charming hotel and staff. Great breakfast with lots of home made baking changing daily. Lovely surprise to get a welcome drink. We had the penthouse which was lovely - lots of space to relax and am amazing view. Oh and the location was perfect too. Highly recommended. 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