Title: Top Hotels in San Fransisco District - Compare San Fransisco District Hotels | Expedia.co.uk [Holiday Rentals in San Fransisco District](https://expedia.co.uk/Destinations-In-San-Fransisco-District.d553248635975750662.Holiday-Rental-Destinations)[San Fransisco District Car Hire](https://expedia.co.uk/Destinations-In-San-Fransisco-District.d553248635975750662.Car-Hire-Destinations)[San Fransisco District Holidays](https://expedia.co.uk/San-Fransisco-District.d553248635975750662.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [9 Mar - 10 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975750662&startDate=2026-03-09&endDate=2026-03-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Mar - 11 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975750662&startDate=2026-03-10&endDate=2026-03-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975750662&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [20 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975750662&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for San Fransisco District hotels ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/34474832.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/a93eba24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/w1080h571x0y5-5632f012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Single Room | Desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/0083006b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL VISTA LAGO [](https://www.expedia.co.uk/Nuevo-Santiago-Hotels-HOTEL-VISTA-LAGO.h95675257.Hotel-Information) La Pena 9.4/10 Exceptional (100 reviews) "Great atmosphere around the restaurant and pool. We found it very relaxing in an otherwise busy city. Restaurant makes good meals and the service is great." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Conrad £63 includes taxes & fees 10 Mar - 11 Mar [](https://www.expedia.co.uk/Nuevo-Santiago-Hotels-HOTEL-VISTA-LAGO.h95675257.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15240000/15230100/15230045/3ec28799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/16000000/15240000/15230100/15230045/d889f979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/16000000/15240000/15230100/15230045/6880fd32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Waterslide](https://images.trvl-media.com/lodging/16000000/15240000/15230100/15230045/a4044dcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel La Hacienda [](https://www.expedia.co.uk/Santiago-Hotels-Hotel-La-Hacienda.h15230045.Hotel-Information) Rodrigo Luque 8.6/10 Excellent (4 reviews) "Nos gustó mucho la decoración, la comida excelente, encontrar un espacio temático mexicano fuera de este país es muy especial" ![Panama](https://a.travel-assets.com/egds/marks/flags/pa.svg) Anonymous traveller [](https://www.expedia.co.uk/Santiago-Hotels-Hotel-La-Hacienda.h15230045.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/126000000/125160000/125156600/125156525/bc379b20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/126000000/125160000/125156600/125156525/9f57b914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/126000000/125160000/125156600/125156525/525d00c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Internet](https://images.trvl-media.com/lodging/126000000/125160000/125156600/125156525/df462606.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Perfect 1-bedroom bungalow with AC in peaceful Playa reina [](https://www.expedia.co.uk/Canto-Del-Llano-Hotels-Perfect-1-Bedroom-Bungalow-With-AC-In-Peaceful-Playa-Reina.h125156525.Hotel-Information) Santiago £80 includes taxes & fees 10 Mar - 11 Mar [](https://www.expedia.co.uk/Canto-Del-Llano-Hotels-Perfect-1-Bedroom-Bungalow-With-AC-In-Peaceful-Playa-Reina.h125156525.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/26000000/25090000/25087400/25087317/94ab9042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/26000000/25090000/25087400/25087317/3e8ff1a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25090000/25087400/25087317/8755f27f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Quadruple Room, 2 Double Beds, Shared Bathroom, Corner | Free WiFi](https://images.trvl-media.com/lodging/26000000/25090000/25087400/25087317/d0a031e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal Brisas Calobreñas [](https://www.expedia.co.uk/Calobre-Hotels-Hostal-Brisas-Calobrenas.h25087317.Hotel-Information) Calobre [](https://www.expedia.co.uk/Calobre-Hotels-Hostal-Brisas-Calobrenas.h25087317.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-23&endDate=2026-03-24®ionId=553248635975750662&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_SPRING_PROMO_553248635975750662) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-San-Fransisco-District.d553248635975750662.Hotel-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-San-Fransisco-District.d553248635975750662.Hotel-Destinations) ## Top San Fransisco District Hotel Reviews ![Hotel Anachoreo](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/32d16900_y.jpg) ### Hotel Anachoreo 10/10 Excellent "This is a great place to unwind and enjoy the spectacular view. The room was quiet, clean and comfortable. The breakfast was convenient and large. I highly recommend the massage. " [](https://expedia.co.uk/Santa-Fe-Hotels-Hotel-Anachoreo.h27775675.Hotel-Information) ![Hotel Mykonos Panama](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/1db3bbb0_y.jpg) ### Hotel Mykonos Panama 10/10 Excellent "Nice" [](https://expedia.co.uk/Santiago-Hotels-Hotel-Mykonos-Panama.h5270392.Hotel-Information) ![Hotel Gran David](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/bb11ab13_y.jpg) ### Hotel Gran David 10/10 Excellent "Mi experiencia reciente en el Hotel Gran David en Veraguas ha sido muy positiva, especialmente al notar una evolución muy favorable en comparación con mi estancia de hace tres años. El personal es sumamente amable y atento, lo que te hace sentir bienvenido desde el primer instante, y tanto las instalaciones como el buffet de desayuno son de excelente calidad. Como único punto a considerar, el hotel se encuentra justo a un costado de la Carretera Panamericana, por lo que el ruido del tráfico constante, especialmente de camiones pesados, puede ser notable; si eres de sueño ligero, recomiendo solicitar una habitación alejada de la carretera. Asimismo, la administración debería mejorar la señalización de sus estacionamientos, ya que existen plazas adicionales detrás del hotel que no resultan obvias al llegar. En general, es una opción muy sólida y recomendable en la zona por su gran servicio y oferta gastronómica." [](https://expedia.co.uk/Santiago-Hotels-Hotel-Gran-David.h12003378.Hotel-Information) ![HOTEL VISTA LAGO](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/34474832_y.jpg) ### HOTEL VISTA LAGO 10/10 Excellent "Great place to stay, quiet…" [](https://expedia.co.uk/Nuevo-Santiago-Hotels-HOTEL-VISTA-LAGO.h95675257.Hotel-Information) ![Hotel Galería](https://images.trvl-media.com/lodging/28000000/27580000/27570800/27570722/7a530baa_y.jpg) ### Hotel Galería 10/10 Excellent "Clean room, comfy bed. Great restaurant with a free breakfast. What more could two weary travelers want. " [](https://expedia.co.uk/Santiago-Hotels-Hotel-Galeria.h27570722.Hotel-Information) ![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg) ### Private Over the Water Cabin on San Blas Island 10/10 Excellent "Very nice. And I liked the food " [](https://expedia.co.uk/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in San Fransisco District - [San Francisco Hotels ](https://expedia.co.uk/San-Francisco-Hotels.d829297101453152256.Travel-Guide-Hotels) - [Los Hatillos Hotels ](https://expedia.co.uk/Los-Hatillos-Hotels.d829297110689017856.Travel-Guide-Hotels) - [San Juan Hotels ](https://expedia.co.uk/San-Juan-Hotels.d829297113390129152.Travel-Guide-Hotels) - [Corral Falso Hotels ](https://expedia.co.uk/Corral-Falso-Hotels.d829297104315764736.Travel-Guide-Hotels) - [Remance Hotels ](https://expedia.co.uk/Remance-Hotels.d829297107396464640.Travel-Guide-Hotels) - [San José Hotels ](https://expedia.co.uk/San-Jose-Hotels.d829297115954941952.Travel-Guide-Hotels) ### Explore more hotels - [Hotel Mykonos Panama ](https://expedia.co.uk/Santiago-Hotels-Hotel-Mykonos-Panama.h5270392.Hotel-Information) - [Hotel Gran David ](https://expedia.co.uk/Santiago-Hotels-Hotel-Gran-David.h12003378.Hotel-Information) - [Private Over the Water Cabin on San Blas Island ](https://expedia.co.uk/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information) - [HOTEL VISTA LAGO ](https://expedia.co.uk/Nuevo-Santiago-Hotels-HOTEL-VISTA-LAGO.h95675257.Hotel-Information) - [Hotel Galería ](https://expedia.co.uk/Santiago-Hotels-Hotel-Galeria.h27570722.Hotel-Information) - [Hotel Anachoreo ](https://expedia.co.uk/Santa-Fe-Hotels-Hotel-Anachoreo.h27775675.Hotel-Information) - [La Qhia Eco Retreat ](https://expedia.co.uk/Santa-Fe-Hotels-La-Qhia-Eco-Retreat.h29430099.Hotel-Information) - [Hotel Plaza ](https://expedia.co.uk/Santiago-Hotels-Hotel-Plaza.h23252582.Hotel-Information) - [Hotel La Hacienda ](https://expedia.co.uk/Santiago-Hotels-Hotel-La-Hacienda.h15230045.Hotel-Information) - [Complete private villa ](https://expedia.co.uk/Olivias-Village-1927.h123049080.Hotel-Information) [See a list of all hotels in San Fransisco District](https://expedia.co.uk/All-San-Fransisco-District-Hotels.d553248635975750662.Travel-Guide-City-All-Hotels) ### Expedia's Latest Trends Hotels - 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