San Fransisco District Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Top San Fransisco District Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Casa Panamá

Hotel Casa Panamá

4 out of 5
Casco Viejo
Price was £1,034, price is now £748 per person
£748
per person
11 Aug - 20 Aug
found 2 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
7.6/10 Good! (682 reviews)
Todo muy cerca , muy buena ubicación

Reviewed on 22 May 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was £2,118, price is now £1,238 per person
£1,238
per person
11 Aug - 20 Aug
found 2 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
9.2/10 Wonderful! (1,017 reviews)
Central to everything

Reviewed on 20 May 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was £1,745, price is now £1,070 per person
£1,070
per person
11 Aug - 20 Aug
found 2 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
8.4/10 Very Good! (1,524 reviews)
Was a good experience overall

Reviewed on 24 May 2026

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
San Francisco
Price was £1,267, price is now £921 per person
£921
per person
11 Aug - 20 Aug
found 2 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
9/10 Wonderful! (1,010 reviews)
Great hotel and close to everything. Beautiful view to the city, clean and safe.

Reviewed on 24 May 2026

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5 out of 5
Casco Viejo
Price was £1,943, price is now £1,412 per person
£1,412
per person
11 Aug - 20 Aug
found 2 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
9.8/10 Exceptional! (648 reviews)
Easily one the best hotel stays ever. Great property. Great food. Excellent service.

Reviewed on 14 May 2026

San Fransisco District Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós

Top hotels in San Fransisco District

Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway Nuevo Santiago Veraguas
Fully refundableReserve now, pay when you stay
The price is £66 per night from 26 May to 27 May
£66
26 May - 27 May
includes taxes & fees
Hotel Mykonos Panama
Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana Santiago Veraguas
Fully refundableReserve now, pay when you stay
The price is £58 per night from 26 May to 27 May
£58
26 May - 27 May
includes taxes & fees
8.6/10 Excellent! (404 reviews)
"Tuvimos una cena muy agradable mi hija y yo. Disfrutamos de las almejas, una fantástica corvina y la pasta de tres hongos, acompañadas de vino blanco. Todo estuvo excelente."

Reviewed on 21 May 2026

Hotel Gran David
HOTEL VISTA LAGO

HOTEL VISTA LAGO

3 out of 5
Rincón Largo La Pena Santiago de Veraguas
Fully refundableReserve now, pay when you stay
The price is £58 per night from 19 Jun to 20 Jun
£58
19 Jun - 20 Jun
includes taxes & fees
9.4/10 Exceptional! (112 reviews)
"Lugar exclusivo. Atención personalizada. Hermosa vista. Muy privado y silencioso."

Reviewed on 8 May 2026

HOTEL VISTA LAGO
See all 25 properties in San Fransisco District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a San Fransisco District travel package cost?
Our San Fransisco District packages, which begin at just £748, are the best way to save money. Select your favourite hotels, flights and more to create a personalized trip.
If I'm not able to travel, can I cancel my San Fransisco District travel package?
Yes, you can cancel your San Fransisco District booking if your travel plans have changed. Whether you'll incur a fee or not depends on your hotel, airline or car rental company. It may be possible to change or cancel your booking for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
How do I get a cheap travel package to San Fransisco District?
Lock in flights that fit your schedule, add a hotel room to your booking and watch the savings rack up with a San Fransisco District travel package. It's as easy as that! From hotels and flights to activities and rental cars, Expedia makes travelling cheaply a cinch. And with more than 550 air carriers and 1,000,000 properties globally to pick from, you'll never be short of choice.
Does Expedia offer Book Now, Pay Later San Fransisco District holidays?
Expedia has partnered with online lender Klarna to make booking your next break easier on your wallet. Paying by instalment means you can spread the costs of your next big holiday, leaving you with more cash to splash while you're away. Klarna has several payment plans to pick from, so you're sure to find something that fits your budget. Browse these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month sounds right for you, Klarna can help. Paying in easy monthly instalments will make that dream holiday possible.
  • Pay in instalments holidays: If you'd prefer to pay for your getaway in multiple transactions, holidays paid in instalments might be right for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: Hitting the "book now" button is much easier with this payment option. Simply put down a small deposit on your escape and then start packing your suitcase.

How far in advance should I book my San Fransisco District holiday?
Your safest bet is to book early. Air carriers usually advertise flights around a year in advance, and this is when you can pick up some of the cheapest prices. Boss just told you to use up some holiday time next week? No sweat. Expedia are never short of fantastic deals to send you on the getaway of your dreams, at a price you can afford.
What does an Expedia San Fransisco District travel package include?
You can choose from any combination of flights, rental cars and hotels. Once you've made your booking, you can also add on experiences and tours. Want to pick your airfare class? That's easy to do too. The choice is yours when it comes to putting together your perfect San Fransisco District trip.
What should I know before booking a San Fransisco District travel package?
Booking all the parts of your getaway together is a great way to save. Bundle your car rentals, flights and hotels into a tidy little package. But it's not just hotels. Expedia has all sorts of properties, including holiday rentals such as oceanfront condos and spacious residences. Your choices are almost endless!
Can I choose my airline with a San Fransisco District Expedia travel package?
Yes, the choice is yours. We have access to over 550 airlines worldwide, so you can design your San Fransisco District holiday according to your travel preferences.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.