Title: Top Hotels in Orangeburg County - Compare Orangeburg County Hotels | Expedia.co.uk [Holiday Rentals in Orangeburg County](https://expedia.co.uk/Destinations-In-Orangeburg-County.d553248635996998003.Holiday-Rental-Destinations)[Orangeburg County Car Hire](https://expedia.co.uk/Destinations-In-Orangeburg-County.d553248635996998003.Car-Hire-Destinations)[Orangeburg County Holidays](https://expedia.co.uk/Orangeburg-County.d553248635996998003.Holidays-City-Breaks) ![DEG7A9 Bald cypress forest in autumn at the Cuddo Unit of the Santee Refuge, SC.](https://images.trvl-media.com/place/9953/a26d5a16-8cd2-405d-94ab-122a2f63e661.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/9953/a26d5a16-8cd2-405d-94ab-122a2f63e661.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Orangeburg County Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/2/d91715fa11e9d5570856838fd5bd4287.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Orangeburg [](https://expedia.co.uk/Orangeburg-Hotels.d6058108.Travel-Guide-Hotels) ## Check prices for these dates Tonight [22 Feb - 23 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635996998003&startDate=2026-02-22&endDate=2026-02-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [23 Feb - 24 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635996998003&startDate=2026-02-23&endDate=2026-02-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635996998003&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635996998003&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Orangeburg County hotels ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/320acff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very good (1,435 reviews) "Room were very clean and staff was very helpful. I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charolette £66 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/40f69ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee [](https://www.expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) Santee 9.2/10 Wonderful (730 reviews) "Large, clean room, friendly staff, nice breakfast. Would stay again. Also a nice Mexican restaurant nearby for dinner. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £89 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/99c8fb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c836e9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/eb4d1288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c5155ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) Orangeburg 9.2/10 Wonderful (1,006 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas £94 includes taxes & fees 9 Mar - 10 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2556x0y4-5cb4ef80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2558x3y4-5a11a251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2557x0y3-a96a0495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2482x3y0-b2c385e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) Orangeburg 7.8/10 Good (1,003 reviews) "Clean rooms, good location, nice and polite staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenya £78 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) Santee 9.8/10 Exceptional (1,005 reviews) "Room had everything we wanted... very clean & fresh, microwave, fridge, comfy beds. Hotel was very nice and close to everything needed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcia £103 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Free breakfast ](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Iron/ironing board, free cots/infant beds, free rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/1ffbf2b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) Santee 9.6/10 Exceptional (1,001 reviews) "Liked the size of the room, the staff and the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Virginia £101 includes taxes & fees 3 Mar - 4 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/a0deabe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/71b46ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/a9d1fec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) Orangeburg 8.4/10 Very good (728 reviews) "Overall a great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Troy £69 includes taxes & fees 4 Mar - 5 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5f0b6fe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5ef3d5ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) Santee 8.2/10 Very good (1,003 reviews) "Everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie £95 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/c19ebd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/c4341f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/ee5c02dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/37c1c14e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Orangeburg by IHG [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) Orangeburg 8.6/10 Excellent (807 reviews) "Accommodations were great. The staff is very courteous. Overall I enjoyed my stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Calvin £88 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) ![Room, 2 Queen Beds, Accessible, Non Smoking (Efficiency) | Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/2dd4e6c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/2f324808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/cc6b1fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/c5e580c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) Orangeburg 8.0/10 Very good (578 reviews) "Nice room and great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle £87 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/67da47be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/044c704d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn [](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) Santee 8.8/10 Excellent (1,004 reviews) "Courteous reception,clean rooms and great breakfast! Have been there many times in the last 15 years and I will return.!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Roger £92 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/44be5cac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/ca4d16db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/e844503c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) Orangeburg 9.4/10 Exceptional (783 reviews) "We travel regularly and this was the best breakfast of any of the places we had stayed. Facility was clean and service was friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet £107 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e5b64ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e0b4742d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/8229e487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) Orangeburg 8.8/10 Excellent (703 reviews) "3rd stay at this location would highly recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Athanassios £93 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) ![Frette Italian sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/0b55a618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall) | Frette Italian sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) Santee 8.0/10 Very good (1,006 reviews) "Clean rooms, nice staff, decent breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale £89 includes taxes & fees 24 Feb - 25 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/d4b79aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/c4ff1065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Smoking | Bathroom sink](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/13cfcb42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) Orangeburg 8.2/10 Very good (1,001 reviews) "The evening clerk is a joy, so friendly and helpful! Room clean and comfortable. Nice stay for passing through. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra £65 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/4c792a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/50891687.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee I-95 [](https://www.expedia.co.uk/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) Santee 6.0/10 (477 reviews) "Clean room but needs an exhaust fan in the bathroom " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leesa £49 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/b15e751d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3e8501ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/581bc335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/cfcbf535.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Orangeburg North [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) Orangeburg 6.0/10 (1,000 reviews) "The rooms were clean and staff was courteous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yojuana £47 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) ![Suite, 1 King Bed, Accessible, Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/81259c64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/706081d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/d44bb419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/3f3e2740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information) Orangeburg 6.2/10 (637 reviews) "Clean and staff very pleasant" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Larry £52 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/ca4e9299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/7655013c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/fd9a2ff0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham, Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) Orangeburg 6.8/10 (917 reviews) "Always a pleasure to stay, staff is very welcoming and the breakfast is a great plus!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra £47 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) ![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Tent | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/9123f55d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Terrace/patio](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/w4138h5635x0y0-48933ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/b0419165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bells Marina & Resort [](https://www.expedia.co.uk/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) Eutawville 8.6/10 Excellent (89 reviews) "Super quaint, quiet, nice little get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen [](https://www.expedia.co.uk/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-08&endDate=2026-03-09®ionId=553248635996998003&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_SPRING_PROMO_553248635996998003) ## Great weekend hotel deals in Orangeburg County, SC ### Showing deals for:**6 Mar - 8 Mar** ### Image gallery for Beautiful brick home w/ large porch and 3 bedrooms ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/w1198h1600x0y0-8fa30947.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Beautiful brick home w/ large porch and 3 bedrooms Bowman **9.2/10**Wonderful (5 reviews) 7% off £339 for 2 nights, 1 home £170 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-06&endDate=2026-03-08&selected=112528151&adults=2) ### Image gallery for Lake Marion - Majestic Big Water View! ![Exterior](https://images.trvl-media.com/lodging/105000000/104220000/104211700/104211609/d39bc1a3.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Lake Marion - Majestic Big Water View! Santee **10/10**Exceptional (9 reviews) 6% off £517 for 2 nights, 1 apartment £259 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-06&endDate=2026-03-08&selected=104211609&adults=2) ### Image gallery for The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot. ![Property grounds](https://images.trvl-media.com/lodging/55000000/54180000/54171600/54171514/6ea35a79.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot. Eutawville **10/10**Exceptional (39 reviews) 6% off £364 for 2 nights, 1 home £182 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-06&endDate=2026-03-08&selected=54171514&adults=2) ### Image gallery for Waterfront Condo on Lake Marion ![Interior](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/67115d00.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Waterfront Condo on Lake Marion Santee **10/10**Exceptional (6 reviews) 7% off £801 for 2 nights, 1 room £401 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-06&endDate=2026-03-08&selected=102018216&adults=2) ### Image gallery for Bells Marina & Resort ![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Bells Marina & Resort Eutawville **8.6/10**Excellent (89 reviews) 16% off £189 for 2 nights, 1 room £95 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-06&endDate=2026-03-08&selected=91244689&adults=2) ### Image gallery for Best Western Plus Santee Inn ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Best Western Plus Santee Inn Santee **8.8/10**Excellent (1,004 reviews) 20% off £239 for 2 nights, 1 room £120 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-06&endDate=2026-03-08&selected=21863&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations) ## Top Orangeburg County Hotel Reviews ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg) ### Fairfield Inn & Suites by Marriott Santee 10/10 Excellent "The room was spacious. " [](https://expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Comfort Inn & Suites Orangeburg](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f_y.jpg) ### Comfort Inn & Suites Orangeburg 10/10 Excellent "Great accommodations, friendly and kind staff plus the bonus daily breakfast options for their guest as well." [](https://expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e_y.jpg) ### Comfort Inn & Suites Santee 10/10 Excellent "Everything was great! The staff, the room" [](https://expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "Very clean amenities " [](https://expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3_y.jpg) ### Best Western Plus Santee Inn 10/10 Excellent "Courteous reception,clean rooms and great breakfast! Have been there many times in the last 15 years and I will return.!" [](https://expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5_y.jpg) ### Tru by Hilton Orangeburg 10/10 Excellent "Very clean room but on the small side as compared to other rooms we stay in." [](https://expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg) ### Tru By Hilton Santee 10/10 Excellent "No frills but comfortable, clean, modern establishment with friendly, welcoming staff. Better than most conveniently situated motels near 95\. Good value. " [](https://expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27_y.jpg) ### Fairfield Inn by Marriott Orangeburg 10/10 Excellent "Great room and staff" [](https://expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg) ### Baymont by Wyndham Santee 10/10 Excellent "Clean room, quiet, good continental breakfast. Friendly staff." [](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Orangeburg County - [Santee Hotels ](https://expedia.co.uk/Santee-Hotels.d9953.Travel-Guide-Hotels) - [Orangeburg Hotels ](https://expedia.co.uk/Orangeburg-Hotels.d6058108.Travel-Guide-Hotels) - [Eutawville Hotels ](https://expedia.co.uk/Eutawville-Hotels.d3000455924.Travel-Guide-Hotels) - [Holly Hill Hotels ](https://expedia.co.uk/Holly-Hill-Hotels.d3000455972.Travel-Guide-Hotels) - [Vance Hotels ](https://expedia.co.uk/Vance-Hotels.d3000456153.Travel-Guide-Hotels) - [Bowman Hotels ](https://expedia.co.uk/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [Neeses Hotels ](https://expedia.co.uk/Neeses-Hotels.d3000456036.Travel-Guide-Hotels) - [Cordova Hotels ](https://expedia.co.uk/Cordova-Hotels.d553248634998610573.Travel-Guide-Hotels) - [Cope Hotels ](https://expedia.co.uk/Cope-Hotels.d3000455896.Travel-Guide-Hotels) - [North Hotels ](https://expedia.co.uk/North-Hotels.d553248634999378506.Travel-Guide-Hotels) - [Rowesville Hotels ](https://expedia.co.uk/Rowesville-Hotels.d3000353220.Travel-Guide-Hotels) - [Norway Hotels ](https://expedia.co.uk/Norway-Hotels.d553248634998816179.Travel-Guide-Hotels) - [Whetsell Hotels ](https://expedia.co.uk/Whetsell-Hotels.d553248635974902828.Travel-Guide-Hotels) - [Woodford Hotels ](https://expedia.co.uk/Woodford-Hotels.d553248634998789873.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near I.P. Stanback Museum & Planetarium ](https://expedia.co.uk/IP-Stanback-Museum-Planetarium-Hotels.0-l553248621561867626-0.Travel-Guide-Filter-Hotels) ### Hotels near Orangeburg County Airports - [Columbia Metropolitan Airport Hotels ](https://expedia.co.uk/Columbia-Metropolitan-Airport-Hotels.0-aCAE-0.Travel-Guide-Filter-Hotels) - [Charleston Intl. Airport Hotels ](https://expedia.co.uk/Charleston-Intl-Airport-Hotels.0-aCHS-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Tru By Hilton Santee ](https://expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) - [Baymont by Wyndham Santee ](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) - [Tru by Hilton Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) - [Fairfield Inn & Suites by Marriott Santee ](https://expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) - [Hampton Inn Santee-I-95 ](https://expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) - [SpringHill Suites by Marriott Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) - [Travelodge by Wyndham Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) - [Spark by Hilton Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) - [Fairfield Inn by Marriott Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) - [Comfort Inn & Suites Orangeburg ](https://expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) [See a list of all hotels in Orangeburg County](https://expedia.co.uk/All-Orangeburg-County-Hotels.d553248635996998003.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Orangeburg County on Expedia.com ](https://www.expedia.com/Destinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Hotels in Orange County](https://expedia.co.uk/Destinations-In-Orange-County.d603224.Hotel-Destinations) - [All-Inclusive Hotels in San Diego County](https://expedia.co.uk/Destinations-In-San-Diego-County-All-Inclusive-Hotel.0-0-d178304-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Charleston Historic District Hotels](https://expedia.co.uk/Charleston-Historic-District-Charleston-Hotels.0-n6057948-0.Travel-Guide-Filter-Hotels) - [Hotels in San Diego County](https://expedia.co.uk/Destinations-In-San-Diego-County.d178304.Hotel-Destinations) - [All-Inclusive Hotels in Los Angeles County](https://expedia.co.uk/Destinations-In-Los-Angeles-County-All-Inclusive-Hotel.0-0-d6056560-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Beach Resorts & Hotels in San Diego County](https://expedia.co.uk/Destinations-In-San-Diego-County-Beach-Hotels.0-0-d178304-tBeachHotels.Hotel-Filter-Destinations) - [Luxury Hotels in Door County](https://expedia.co.uk/Destinations-In-Door-County-Luxury-Hotel.0-0-d6059811-tLuxuryHotel.Hotel-Filter-Destinations) - [Downtown Charleston Hotels](https://expedia.co.uk/Downtown-Charleston-Charleston-Hotels.0-n553248633938969537-0.Travel-Guide-Filter-Hotels) - [Cherry Grove Beach Hotels](https://expedia.co.uk/Cherry-Grove-Beach-North-Myrtle-Beach-Hotels.0-n553248621561867974-0.Travel-Guide-Filter-Hotels) - [Hotels in Door County](https://expedia.co.uk/Destinations-In-Door-County.d6059811.Hotel-Destinations) - [South of the Border Hotels](https://expedia.co.uk/South-Of-The-Border-Hamer-Hotels.0-n3000456123-0.Travel-Guide-Filter-Hotels) Flights - [Cheap Flights to Myrtle Beach](https://expedia.co.uk/Cheap-Flights-To-Myrtle-Beach-Intl.d5396813.Travel-Guide-Flights) - [Flights to Orange County](https://expedia.co.uk/Destinations-In-Orange-County.d603224.Flight-Destinations) Cars - [Car hire in Florence](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Florence-Regional.d6027805.Car-Hire-Guide) - [Car hire in Charleston](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Charleston-Intl.d5457987.Car-Hire-Guide) - [Car hire in Orange County](https://expedia.co.uk/Destinations-In-Orange-County.d603224.Car-Hire-Destinations) - [convertible Car Hire in San Diego County](https://expedia.co.uk/Convertible-Car-Rentals-In-San-Diego-County.d178304-tConvertible.Car-Rental-Destination-Class) Activities - [Things to do in San Diego County](https://expedia.co.uk/Things-To-Do-In-San-Diego-County.d178304.Travel-Guide-Activities) - [Things to do in Orange County](https://expedia.co.uk/Things-To-Do-In-Orange-County.d603224.Travel-Guide-Activities) Packages - [Orange County Holidays](https://expedia.co.uk/Orange-County.d603224.Holidays-City-Breaks) - [Family Kingdom Amusement Park](https://expedia.co.uk/Family-Kingdom-Amusement-Park-Myrtle-Beach.d6079999.Attraction) - [Cherry Grove Beach Holidays](https://expedia.co.uk/Cherry-Grove-Beach.d553248621561867974.Holidays-City-Breaks) - [Coastal Grand Mall](https://expedia.co.uk/Coastal-Grand-Mall-Myrtle-Beach.d553248635261002225.Attraction) - [Ripley's Aquarium](https://expedia.co.uk/Ripleys-Aquarium-Myrtle-Beach.d6079963.Attraction) - [San Diego County Holidays](https://expedia.co.uk/San-Diego-County.d178304.Holidays-City-Breaks) General - [Visit North Slope Borough](https://expedia.co.uk/North-Slope-Borough.dx6228899) - [Visit Charleston Historic District](https://expedia.co.uk/Charleston-Charleston-Historic-District.dx6057948) - [Visit Suffolk County](https://expedia.co.uk/Suffolk-County.dx553248635083916458) - [Visit Los Angeles County](https://expedia.co.uk/Los-Angeles-County.dx6056560) - [Visit Harbour Town](https://expedia.co.uk/Hilton-Head-Island-Harbour-Town.dx553248635976470650) ## Frequently asked questions ### How much do hotels in Orangeburg County cost? ### When is the best time to go to Orangeburg County? ### How can I find cheap hotels in Orangeburg County? ### What are the best hotels in Orangeburg County for families? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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