De Soto Holidays from £472

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your De Soto Holiday

Experience the unique character and personality of De Soto with a tailor-made De Soto holiday package. From its welcoming locals to its rich history, you'll never have a boring moment in this city. A trip to De Soto wouldn't be complete without visiting a few top attractions, starting with Victoria Glaces Conservation Area Trailhead. No matter your travel plans or budget, organising a tailored De Soto holiday is a cinch with Expedia.

Top De Soto Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

3.5 out of 5
Price was £568, price is now £472 per person
£472
per person
20 Dec - 25 Dec
found 12 hours ago
Return direct flight included
Midland (MAF) to St. Louis (STL)
8/10 Very good! (1,004 reviews)

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was £805, price is now £489 per person
£489
per person
20 Dec - 25 Dec
found 12 hours ago
Return direct flight included
Midland (MAF) to St. Louis (STL)
9.2/10 Wonderful! (1,677 reviews)
Was clean, room was large and comfortable. Bed was comfortable and stay was very relaxing. Nice simple breakfast with both packaged and fresh food, Was away from the city so was quieter, than staying in other towns. Staff was very friendly and helpful.

Reviewed on 12 Nov 2026

The Cheshire

The Cheshire

4 out of 5
Price was £779, price is now £604 per person
£604
per person
20 Dec - 25 Dec
found 12 hours ago
Return direct flight included
Midland (MAF) to St. Louis (STL)
8.8/10 Excellent! (1,010 reviews)

Moonrise Hotel

Moonrise Hotel

4 out of 5
Delmar Loop
Price was £765, price is now £598 per person
£598
per person
20 Dec - 25 Dec
found 12 hours ago
Return direct flight included
Midland (MAF) to St. Louis (STL)
9/10 Wonderful! (2,047 reviews)

Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
Edmundson
Price was £696, price is now £577 per person
£577
per person
20 Dec - 25 Dec
found 12 hours ago
Return direct flight included
Midland (MAF) to St. Louis (STL)
8/10 Very good! (1,002 reviews)

De Soto Essential Information

Language
English
Currency
U.S dollars
Population
6,500
Max Temp Winter
7ºC
Max Temp Summer
32ºC

Top hotels in De Soto

Gated 35-Acre De Soto Estate: Pool, Lake & Patio!

Gated 35-Acre De Soto Estate: Pool, Lake & Patio!

De Soto MO
10/10 Exceptional! (9 reviews)
"Hosts were responsive and very helpful! We had a larger group and it fit everyone comfortably all of the amenities made it so much fun! Great property and would definitely recommend!"

Reviewed on 11 Oct 2026

Get rates
Gated 35-Acre De Soto Estate: Pool, Lake & Patio!
Secluded cabin on private property

Secluded cabin on private property

De Soto MO
10/10 Exceptional! (82 reviews)
"The perfect getaway place. Fall colors, quiet surroundings and beautifully decorated cabin. The thoughtful hosts have created the best possible stay imaginable."

Reviewed on 29 Oct 2026

Get rates
Secluded cabin on private property
82 Acre Hobby Farm with Lincoln Log Cabin

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto MO
The price is £198 per night from 15 Nov to 16 Nov
£198
15 Nov - 16 Nov
includes taxes & fees
10/10 Exceptional! (49 reviews)
"Very clean and decorated for Halloween. Nothing spooky, just sweet. Very rural (what we were going for!) but close to De Soto and Crystal City MO. Had deer (5) and wild turkey (2) each morning. The entire space is a loft, but easy to climb the stairs. Had a great time."

Reviewed on 12 Oct 2026

82 Acre Hobby Farm with Lincoln Log Cabin
See all 206 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Stay near popular De Soto attractions

Eastside Community Park

This area park offers a playground, basketball court, and shaded pavilion for family gatherings. Enjoy a picnic under mature trees or shoot hoops while children explore the age-appropriate play equipment.
See properties

Frequently asked questions

How much does a De Soto travel package cost?
Our De Soto packages, which start from just £472, are an ideal way to save precious money. Handpick your favourite hotels, flights and rental car to create your ideal itinerary.
If I'm not able to travel, can I cancel my De Soto travel package?
If your holiday plans in De Soto have changed, it's good to know that you can cancel or amend your booking. If you booked in the last 24 hours, you may be eligible for a refund. If your booking was made more than 24 hours ago, your hotel, airline or car rental company may impose a fee. To learn more, check our Customer Service Portal.
How do I get a cheap travel package to De Soto?
Just imagine all the wonderful things you could do in De Soto with a pile of extra cash in your wallet. Watch your savings stack up when you combine your travel bookings into a De Soto travel package. You have loads of choice when you book your trip with Expedia too. In fact, you can take your pick of more than 550 air carriers and 1,000,000 hotels worldwide. Whether you're heading away with the family or going it alone, planning a getaway to De Soto is better with a package.
Does Expedia offer Book Now, Pay Later De Soto holidays?
Your bank balance shouldn't stop you from taking a holiday, so Expedia has come up with a solution to help. Now that we've teamed up with online lender Klarna, it's easier than ever to book a terrific getaway without draining your savings. Klarna offers flexible payment options at checkout that take the stress out of budgeting for your trip. Check out these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month works for you, Klarna offers just that! Paying in convenient monthly instalments will make your holiday dreams possible.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay off your trip over multiple transactions.
  • Low deposit holidays: If paying a small percentage of your trip (rather than the total upfront) makes it easier to hit that "book now" button, go for a low deposit holiday payment plan from Klarna.

What are the top hotels in De Soto?
If it's your very first time in De Soto, make a reservation at Quality Inn Festus or Quality Inn & Suites Arnold - St Louis. Both hotels offer friendly service and are favourites among many savvy travellers.
How far in advance should I book my De Soto holiday?
It can be hard to know exactly when the best time is to book your holiday to De Soto. But usually the earlier you book, the lower the prices. Sometimes, you can book your flights and hotels up to a year before your departure date. If you're considering a last-minute getaway, no need to worry! There are plenty of fantastic bargains advertised on Expedia every day.
What does an Expedia De Soto travel package include?
Flights, hotels and car rentals — we bring you the very best deals. All you'll have to do is decide on your preferred combination. After you've made your booking, you can add on the exciting stuff like day tours and sightseeing activities. Our travel packages make it simple to create an awesome De Soto holiday.
What should I know before booking a De Soto travel package?
Whether it's relaxation or adventure you're seeking, a De Soto travel package lets you organise your escape your way. Plus, you'll get access to great discounts when you combine your accommodation with your flights and rental car. The more you bundle, the more you'll save!
Can I choose my airline with a De Soto Expedia travel package?
Yes, the choice is yours. We offer more than 550 airlines throughout the world, so you can customize your De Soto getaway according to your style and budget.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.