Title: Cross Border Xpress in Otay Mesa | Expedia.co.uk [Cross Border Xpress Hotels](https://expedia.co.uk/Cross-Border-Xpress-Hotels.0-l938550730988875776-0.Travel-Guide-Filter-Hotels)[Cross Border Xpress Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Cross-Border-Xpress.d938550730988875776.Car-Hire-Guide)[Otay Mesa Holidays](https://expedia.co.uk/Otay-Mesa.d6263723.Holidays-City-Breaks) # Cross Border Xpress ## Visit Cross Border Xpress Activities --- --- ## Plan a trip to see Cross Border Xpress Price found within the past 48 hours. Click for updated prices. ![City24 Hotel Little Italy Mission Hills](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6ef835b1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### City24 Hotel Little Italy Mission Hills Middletown £1,480 per person 9 Jun - 12 Jun found 12 hours ago Return flight included London (STN) to San Diego (SAN) 9.6/10 Exceptional! (127 reviews) Large apartment type room. Very clean, home feel, near airport. Super friendly and helpful staff. Would recommend 10/10!!! Reviewed on 26 Mar 2026 ![Avalon 2 Unit Buyout Avantstay Mins to Gaslampbeautiful Deck w/ BBQ](https://images.trvl-media.com/lodging/84000000/83970000/83963100/83963009/677bfefa_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Avalon 2 Unit Buyout Avantstay Mins to Gaslampbeautiful Deck w/ BBQ Middletown £2,105 per person 9 Jun - 12 Jun found 12 hours ago Return flight included London (STN) to San Diego (SAN) No reviews ![Avalon III by Avantstay Mins to Gaslamp, Zoo & Airport Beautiful Deck w/ BBQ](https://images.trvl-media.com/lodging/84000000/83970000/83963000/83962973/0e6caa30_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Avalon III by Avantstay Mins to Gaslamp, Zoo & Airport Beautiful Deck w/ BBQ Middletown £1,620 per person 9 Jun - 12 Jun found 12 hours ago Return flight included London (STN) to San Diego (SAN) No reviews ### Popular places to visit #### High Performance Center in Tijuana Catch an event at High Performance Center in Tijuana during your trip to Tijuana. 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[](https://expedia.co.uk/Alameda-Otay-Tijuana.d553248635976357197.Attraction) --- ## Top Hotel Deals ## Check availability on hotels close to Cross Border Xpress [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=938550730988875776&startDate=2026-03-30&endDate=2026-03-31)[30 Mar - 31 Mar](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=938550730988875776&startDate=2026-03-30&endDate=2026-03-31) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=938550730988875776&startDate=2026-03-31&endDate=2026-04-01)[31 Mar - 1 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=938550730988875776&startDate=2026-03-31&endDate=2026-04-01) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=938550730988875776&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026)[3 Apr - 5 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=938550730988875776&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=938550730988875776&startDate=10%2F04%2F2026&endDate=12%2F04%2F2026)[10 Apr - 12 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=938550730988875776&startDate=10%2F04%2F2026&endDate=12%2F04%2F2026) ![Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/3f975189_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG 2296 Niels Bohr Ct San Diego CA [](https://expedia.co.uk/San-Diego-Hotels-Holiday-Inn-Express-Hotel-Suites-San-Diego-Otay-Mesa.h1632358.Hotel-Information) ![Welcome to Sun-Kissed Retreat, your home-away-from-home in sunny San Diego!](https://images.trvl-media.com/lodging/120000000/119360000/119351600/119351566/w1080h718x0y1-6ff5545d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Welcome to Sun-Kissed Retreat, your home-away-from-home in sunny San Diego! 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San Diego CA [](https://expedia.co.uk/San-Diego-Hotels-Luxury-San-Diego-Home-W-Pool.h94350263.Hotel-Information) ![5Bedroom/3Bathroom Beautiful San Diego Home w/ Pool, Spa, AC, W/D & 2-Car Garage](https://images.trvl-media.com/lodging/127000000/126440000/126430200/126430200/fb00a0c4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 5Bedroom/3Bathroom Beautiful San Diego Home w/ Pool, Spa, AC, W/D & 2-Car Garage San Diego CA [](https://expedia.co.uk/San-Diego-Hotels-5Bedroom3Bathroom-Beautiful-San-Diego-Home-W-Pool.h126430200.Hotel-Information) ![Luxe San Diego Getaway w/ Pool & Ocean Views](https://images.trvl-media.com/lodging/95000000/94330000/94320300/94320224/bcb46595_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Luxe San Diego Getaway w/ Pool & Ocean Views San Diego CA [](https://expedia.co.uk/San-Diego-Hotels-San-Diego-Luxury-Vacation-Home-W-Pool.h94320224.Hotel-Information) [See all 521 properties in Cross Border Xpress](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=938550730988875776) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.